Immunization with Single Oral Dose of Alginate-Encapsulated BCG Elicits Effective and Long-Lasting Mucosal Immune Responses

Scandinavian Journal of Immunology

Volumn 82, Issue 6, 2015, Pages 489-497

  Hosseini, M ^a   Dobakhti, F ^b   Pakzad, S R ^c   Ajdary, S ^a  

^a PASTEUR INSTITUTE OF IRAN   (Iran)

^b MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c MINISTRY OF HEALTH AND MEDICAL EDUCATION   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; BCG VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERLEUKIN 4; BACTERIUM ANTIBODY; IMMUNOLOGICAL ADJUVANT; MICROCAPSULE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL GROWTH; BCG VACCINATION; CELL PROLIFERATION; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DRUG EFFICACY; ENCAPSULATION; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; INTERFERON PRODUCTION; LUNG; MOUSE; MUCOSAL IMMUNITY; MYCOBACTERIUM BOVIS BCG; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; SPLEEN CELL; ANIMAL; BAGG ALBINO MOUSE; BLOOD; CUTANEOUS DRUG ADMINISTRATION; IMMUNOLOGY; METABOLISM; MICROCAPSULE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; ORAL DRUG ADMINISTRATION; PROCEDURES; RESPIRATORY TRACT MUCOSA; SPLEEN; TUBERCULOSIS, PULMONARY; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; ALGINATES; ANIMALS; ANTIBODIES, BACTERIAL; BCG VACCINE; CAPSULES; FEMALE; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERFERON-GAMMA; INTERLEUKIN-4; LUNG; MICE; MICE, INBRED BALB C; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; RESPIRATORY MUCOSA; SPLEEN; TUBERCULOSIS, PULMONARY; VACCINATION;

EID: 84945307905     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/sji.12351     Document Type: Article

References (26)

1. Flynn JL, Chan J. Tuberculosis: latency and reactivation. Infect Immun 2001;69:4195-201.
2. Gupta A, Kaul A, Tsolaki AG, Kishore U, Bhakta S. Mycobacterium tuberculosis: immune evasion, latency and reactivation. Immunobiology 2012;217:363-74.
3. Dye C, Williams BG. The population dynamics and control of tuberculosis. Science 2010;328:856-61.
4. Nunn P, Williams B, Floyd K, Dye C, Elzinga G, Raviglione M. Tuberculosis control in the era of HIV. Nat Rev Immunol 2005;5:819-26.
5. Colditz GA, Berkey CS, Mosteller F et al. The efficacy of bacillus Calmette-Guerin vaccination of newborns and infants in the prevention of tuberculosis: meta-analyses of the published literature. Pediatrics 1995;96:29-35.
6. Yuki Y, Kiyono H. Mucosal vaccines: novel advances in technology and delivery. Expert Rev Vaccines 2009;8:1083-97.
7. Williams A, Reljic R, Naylor I et al. Passive protection with immunoglobulin A antibodies against tuberculous early infection of the lungs. Immunology 2004;111:328-33.
8. Lopez Y, Yero D, Falero-Diaz G et al. Induction of a protective response with an IgA monoclonal antibody against Mycobacterium tuberculosis 16 kDa protein in a model of progressive pulmonary infection. Int J Med Microbiol 2009;299:447-52.
9. Diogo GR, Reljic R. Development of a new tuberculosis vaccine: is there value in the mucosal approach? Immunotherapy 2014;6:1001-13.
10. Olivares N, Leon A, Lopez Y et al. The effect of the administration of human gamma globulins in a model of BCG infection in mice. Tuberculosis 2006;86:268-72.
11. Chen L, Wang J, Zganiacz A, Xing Z. Single intranasal mucosal Mycobacterium bovis BCG vaccination confers improved protection compared to subcutaneous vaccination against pulmonary tuberculosis. Infect Immun 2004;72:238-46.
12. Davis SS. Nasal vaccines. Adv Drug Deliv Rev 2001;51:21-42.
13. Lotte A, Wasz-Hockert O, Poisson N, Dumitrescu N, Verron M, Couvet E. BCG complications. Estimates of the risks among vaccinated subjects and statistical analysis of their main characteristics. Adv Tuberc Res 1984;21:107-93.
14. Lagranderie M, Chavarot P, Balazuc AM, Marchal G. Immunogenicity and protective capacity of Mycobacterium bovis BCG after oral or intragastric administration in mice. Vaccine 2000;18:1186-95.
15. Nograles N, Abdullah S, Shamsudin MN, Billa N, Rosli R. Formation and characterization of pDNA-loaded alginate microspheres for oral administration in mice. J Biosci Bioeng 2012;113:133-40.
16. Kim B, Bowersock T, Griebel P et al. Mucosal immune responses following oral immunization with rotavirus antigens encapsulated in alginate microspheres. J Control Release 2002;85:191-202.
17. Ajdary S, Dobakhti F, Taghikhani M, Riazi-Rad F, Rafiei S, Rafiee-Tehrani M. Oral administration of BCG encapsulated in alginate microspheres induces strong Th1 response in BALB/c mice. Vaccine 2007;25:4595-601.
18. Dobakhti F, Rahimi F, Dehpour AR et al. Stabilizing effects of calcium alginate microspheres on Mycobacterium bovis BCG intended for oral vaccination. J Microencapsul 2006;23:844-54.
19. Agarwal T, Narayana SN, Pal K, Pramanik K, Giri S, Banerjee I. Calcium alginate - carboxymethyl cellulose beads for colon targeted drug delivery. Int J Biol Macromol 2015;75:409-417.
20. Otterlei M, Ostgaard K, Skjak-Braek G, Smidsrod O, Soon-Shiong P, Espevik T. Induction of cytokine production from human monocytes stimulated with alginate. J Immunother (1991) 1991;10:286-91.
21. Dobakhti F, Naghibi T, Taghikhani M et al. Adjuvanticity effect of sodium alginate on subcutaneously injected BCG in BALB/c mice. Microbes Infect 2009;11:296-301.
22. Aldwell FE, Tucker IG, de Lisle GW, Buddle BM. Oral delivery of Mycobacterium bovis BCG in a lipid formulation induces resistance to pulmonary tuberculosis in mice. Infect Immun 2003;71:101-8.
23. Balu S, Reljic R, Lewis MJ et al. A novel human IgA monoclonal antibody protects against tuberculosis. J Immunol 2011;186:3113-9.
24. Teitelbaum R, Glatman-Freedman A, Chen B et al. A mAb recognizing a surface antigen of Mycobacterium tuberculosis enhances host survival. Proc Natl Acad Sci USA 1998;95:15688-93.
25. Glatman-Freedman A, Casadevall A. Serum therapy for tuberculosis revisited: reappraisal of the role of antibody-mediated immunity against Mycobacterium tuberculosis. Clin Microbiol Rev 1998;11:514-32.
26. Lagranderie M, Balazuc AM, Abolhassani M et al. Development of mixed Th1/Th2 type immune response and protection against Mycobacterium tuberculosis after rectal or subcutaneous immunization of newborn and adult mice with Mycobacterium bovis BCG. Scand J Immunol 2002;55:293-303.