Stabilizing effects of calcium alginate microspheres on mycobacterium bovis BCG intended for oral vaccination

Journal of Microencapsulation

Volumn 23, Issue 8, 2006, Pages 844-854

  Dobakhti, F ^a   Rahimi, F ^a   Dehpour, A R ^b   Taghikhani, M ^c   Ajdary, S ^c   Rafiei, S ^b   Rafiee Tehrani, M ^a  

^a Tehran University of Medical Sciences   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c PASTEUR INSTITUTE OF IRAN   (Iran)

Author keywords

Alginate; Bacillus Calmette Guerin (BCG); Microsphere; Simulated gastric fluid (SGF); Stability

Indexed keywords

ALGINIC ACID; BCG VACCINE; CALCIUM ALGINATE; MICROSPHERE; OLIVE OIL;

ACIDITY; ARTICLE; BACTERIAL VIABILITY; BCG VACCINATION; CONTROLLED STUDY; CULTURE MEDIUM; DISPERSION; DRUG STABILITY; EMULSION; ENCAPSULATION; GELATION; MYCOBACTERIUM BOVIS; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PH; SIMULATION; STOMACH JUICE; TEMPERATURE; TIME;

ADMINISTRATION, ORAL; ALGINATES; BCG VACCINE; CALCIUM; CAPSULES; DRUG CARRIERS; GASTRIC ACID; GLUCURONIC ACID; GOLD; HEXURONIC ACIDS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MYCOBACTERIUM BOVIS; PARTICLE SIZE; SODIUM; SOLUTIONS; VACCINATION;

EID: 33847346822     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/02652040601034013     Document Type: Article

References (39)

1. Aldwell, FE,.Baird, MA,.Fitzpatrick, CE,.Mclellan, AD,.Cross, ML,.Lambeth, MR and Buchan, GS (2005) Oral vaccination of mice with lipid-encapsulated mycobacterium bovis BCG: Anatomical sites of bacterial replication and immune activity. Immunology and Cell Biology, 83, pp. 549-553.
2. Aldwell, FE,.Cross, ML,.Fitzpatrick, CE,.Lambeth, MR,.Lisle, GW and Buddle, BM (2006) Oral delivery of lipid-encapsulated mycobacterium bovis BCG extends survival of the bacillus in vivo and induces a long-term protective immune response against tuberculosis. Vaccine, 24, pp. 2071-2078.
3. Aldwell, FE,.Keen, DL,.Parlan, NA,.Skinner, MA,.Lisle, GW and Buddle, BM (2003) Oral vaccination with mycobacterium bovis BCG in a lipid formulation induces resistance to pulmonary tuberculosis in brush tail possums. Vaccine, 22, pp. 70-76.
4. Aldwell, FE,.Tukker, IG,.Lisle, GW and Buddle, BM (2003) Oral delivery of mycobacterium bovis BCG in a lipid formulation induces resistance to pulmonary tuberculosis in mice. Infection and Immunity, 71, pp. 101-108.
5. Bhopatkar, D.,.Anal, AK and Stevens, WF (2005) Ionotropic alginate beads for controlled intestinal delivery: Effect of chitosan and barium counter-ions on entrapment and release. Journal of Microencapsulation, 22, pp. 91-100.
6. Boon, C. and Dick, T. (2002) Mycobacterium bovis BCG response regulator essential for hypoxic dormancy. Journal of Bacteriology, 184, pp. 6760-6767.
7. Bowersock, TL,.Hogenesch, H.,.Suckow, M.,.Guimond, P.,.Martin, S.,.Borie, D.,.Torregrosa, S.,.Park, H. and Park, K. (1999) Oral vaccination of animals with antigens encapsulated in alginate microspheres. Vaccine, 17, pp. 1804-1811.
8. Bowersock, TL,.Park, K. and Poter, RE (1899) Alginate-based vaccine compositions.
9. Chattaraj, SC,.Rathinavelu, A. and Das, SK (1999) Biodegradable microparticles of influenza viral vaccine: Comparison of the effects of routes of administration on the in vivo immune response in mice. Journal of Controlled Release, 58, pp. 223-232.
10. Desai, MP,.Labhasetwar, V.,.Amidon, GL and Levy, RJ (1996) Gastrointestinal uptake of biodegradable microparticles: Effect of particle size. Pharmaceutical Research, 13, pp. 1838-1845.
11. Esquisabel, A.,.Hernandez, RM,.Igartua, M.,.Gascon, AR,.Calvo, B. and Pedraz, JL (2000) Effect of lecithins on BCG-alginate-PLL microcapsule particle size and stability upon storage. Journal of Microencapsulation, 17, pp. 363-372.
12. Fine, PEM,.Carneiro, IAM,.Milstien, JB and Clements, CJ (1999) Issues relating to the use of BCG in immunization programmes., World Health Organization, Department of Vaccines and Biologicals, Geneva
13. Gheorghiu, M.,.Lagranderie, M. and Balazuc, AM (1996) Stabilisation of BCG vaccines. New approaches to stabilisation of vaccine potency. Developments in Biological Standards, 87, pp. 251-261.
14. Guo, JF,.Jourdian, GW and Maccallum, DK (1989) Culture and growth characteristics of chondrocytes encapsulated in alginate beads. Connective Tissue Research, 19, pp. 277-297.
15. Kierstan, M. and Bucke, C. (1977) The immobilization of microbial cells, subcellular organelles, and enzymes in calcium alginate gels. Biotechnology and Bioengineering, 19, pp. 387-397.
16. Kim, B.,.Bowersock, T.,.Griebel, P.,.Kidan, A.,.Babuik, LA,.Sanchez, M.,.Attah-poku, S.,.Kaushik, RS and Mutwiri, GK (2002) Mucosal immune response following oral immunization with rotavirus antigens encapsulated in alginate microspheres. Journal of Controlled Release, 85, pp. 191-202.
17. Kremer, L.,.Dupre, L.,.Riveau, G.,.Capron, A. and Locht, C. (1998) Systemic and mucosal immune responses after intranasal administration of recombinant mycobacterium bovis bacillus Calmette-Guerin expressing glutathione S-transferase from schistosoma haematobium. Infection and Immunity, 66, pp. 5669-5676.
18. Kumar, TM,.Paul, W.,.Sharma, CP and Kuriachan, MA (2005) Bioadhesive, pH responsive micromatrix for oral delivery of insulin. Trends in Biomaterials and Artificial Organs, 18, pp. 198-202.
19. Kwok, KK,.Groves, MJ and Burgess, DJ (1991) Production of 5-15μm diameter alginate-polylysine microcapsules by an air-atomization technique. Pharmaceutical Research, 8, pp. 341-344.
20. Lagranderie, M.,.Chavarot, P.,.Balazuc, AM and Marchal, G. (2000) Immunogenicity and protective capacity of mycobacterium bovis BCG after oral or intragastric administration in mice. Vaccine, 18, pp. 1186-1195.
21. Lee, S.,.Ang, WS and Elimelech, M. (2006) Fouling of reverse osmosis membranes by hydrophilic organic matter: Implication for water reuse. Desalination, 187, pp. 313-321.
22. Lee, S. and Elimelech, M. (2006) Relating organic fouling of reverse osmosis membrane to intermolecular adhesion forces. Environmental Science & Technology, 40, pp. 980-987.
23. Lemoine, D.,.Wauters, F.,.Bouchend'homme, S. and Preat, V. (1998) Preparation and characterization of alginate microspheres containing a model antigen. International Journal of Pharmaceutics, 176, pp. 9-19.
24. Lim, A.,.Eleuterio, M.,.Hutter, B.,.Murugasu-Oei, B. and Dick, T. (1999) Oxygen depletion-induced dormancy in mycobacterium bovis BCG. Journal of Bacteriology, 181, pp. 2252-2256.
25. Lin, YH,.Liang, HF,.Chung, CK,.Chen, MC and Sung, HW (2005) Physically crosslinked alginate/N,O-carboxymethyl chitosan hydrogels with calcium for oral delivery of protein drugs. Biomaterials, 26, pp. 2105-2113.
26. Mortatti, RC,.Maia, LC and Fonseca, LS (1987) Absorption of Mycobacterium bovis BCG administered by the oral route. Vaccine, 5, pp. 109-114.
27. Ostberg, T.,.Lund, EM and Graggner, C. (1994) Calcium alginate matrices for oral multiple unit administration: I.v release characteristics in different media. International Journal of Pharmaceutics, 112, pp. 241-248.
28. Plorde, JJ (2004) Mycobacteria. Sherris medical microbiology., pp. 439-456. McGraw-Hill, New York
29. Qurrat-ul-ain,.Sharma, S.,.Lhuller, GK and Garag, SK (2003) Alginate-based oral drug delivery system for tuberculosis: Pharmacokinetics and therapeutic effects. Journal of Antimicrobial Chemotherapy, 51, pp. 931-938.
30. Sankalia, MG,.Mashru, RC,.Sankalia, JM and Sutaria, VB (2005) Papain entrapment in alginate beads for stability improvement and site-specific delivery: Physicochemical characterization and factorial optimization using neural network modeling. AAPS Pharmaceutical Sciences & Technology, 6, pp. E209-E222.
31. Silva, CM,.Ribeiro, AJ,.Figueiredo, M.,.Ferreira, D. and Veiga, F. (2006) Microencapsulation of hemoglobin in chitosan-coated alginate microspheres prepared by emulsification/internal gelation. The AAPS Journal, 7, pp. E903-E913.
32. Simpson, NE,.Grants, SC,.Blackband, SJ and Constantinidis, J. (2003) NMR properties of alginate microbeads. Biomaterials, 24, pp. 4941-4948.
33. Smidsrod, O. and Skjak-Braek, G. (1990) Alginate as immobilization matrix for cells. Trends in Biotechnology, 8, pp. 71-78.
34. Smith, KC,.Plothin, A.,.Stark, JR and Orenstein, A. (1999) Bacillus Calmette-Guerin vaccine. Vaccine., pp. 111-139. WB Saunders Company, Philadelphia
35. Sone, T.,.Nagamori, E.,.Ikeuchi, T.,.Mizukami, A.,.Takakura, Y.,.Kajiyama, S.,.Fukusaki, E.,.Harashima, S.,.Kobayashi, A. and Fukui, K. (2002) A novel gene delivery system in plants with calcium alginate micro-beads. Journal of Bioscience and Bioengineering, 94, pp. 87-91.
36. Suckow, MA,.Bowersock, TL,.Park, H. and Park, K. (1996) Oral immunization of rabbits against pasteurella multocida with an alginate microsphere delivery system. Journal of Biomaterials Science, Polymer Edition, 8, pp. 131-139.
37. Takka, S. and Acarturk, F. (1999) Calcium alginate microparticles for oral administration: I: Effect of sodium alginate type on drug release and drug entrapment efficiency. Journal of Microencapsulation, 16, pp. 275-290.
38. Wan, J.,.Gordon, JB,.Muirhead, K.,.Hickey, MW and Coventry, MJ (1997) Incorporation of nisin in micro-particles of calcium alginate. Letters in Applied Microbiology, 24, pp. 153-158.
39. Yeh, P.,.Ellens, H. and Smith, PL (1998) Physiological consideration in the design of particulate dosage forms for oral vaccine delivery. Advanced Drug Delivery Reviews, 34, pp. 123-133.