메뉴 건너뛰기




Volumn 15, Issue 4, 2015, Pages 455-468

Gene and protein expression of O-GlcNAc-cycling enzymes in human laryngeal cancer

Author keywords

Laryngeal cancer; O GlcNAc; OGA (MGEA5); OGT; Tumor front grading (TFG)

Indexed keywords

ENZYME; MESSENGER RNA; N ACETYLGLUCOSAMINE; O GLCNACASE; O LINKED BETA N ACETYLGLUCOSAMINE TRANSFERASE; UNCLASSIFIED DRUG; HISTONE ACETYLTRANSFERASE; HYALURONOGLUCOSAMINIDASE; MGEA5 PROTEIN, HUMAN; N ACETYLGLUCOSAMINYLTRANSFERASE; PROTEOME; TUMOR ANTIGEN;

EID: 84945257368     PISSN: 15918890     EISSN: 15919528     Source Type: Journal    
DOI: 10.1007/s10238-014-0318-1     Document Type: Article
Times cited : (29)

References (38)
  • 1
    • 84896322689 scopus 로고    scopus 로고
    • Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology
    • COI: 1:CAS:528:DC%2BC2cXks1Smtrw%3D, PID: 24524620
    • Vaidyanathan K, Durning S, Wells L. Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology. Crit Rev Biochem Mol Biol. 2014;49(2):140–63.
    • (2014) Crit Rev Biochem Mol Biol , vol.49 , Issue.2 , pp. 140-163
    • Vaidyanathan, K.1    Durning, S.2    Wells, L.3
  • 2
    • 77951935988 scopus 로고    scopus 로고
    • Mechanism, structure, and inhibition of O-GlcNAc processing enzymes
    • COI: 1:CAS:528:DC%2BC3cXisVKlsLo%3D, PID: 20396401
    • Gloster TM, Vocadlo DJ. Mechanism, structure, and inhibition of O-GlcNAc processing enzymes. Curr Signal Transduct Ther. 2010;5(1):74–91.
    • (2010) Curr Signal Transduct Ther , vol.5 , Issue.1 , pp. 74-91
    • Gloster, T.M.1    Vocadlo, D.J.2
  • 3
    • 77953713601 scopus 로고    scopus 로고
    • Modulation of transcription factor function by O-GlcNAc modification
    • PID: 20202486
    • Ozcan S, Andrali SS, Cantrell JE. Modulation of transcription factor function by O-GlcNAc modification. Biochim Biophys Acta. 2010;1799(5–6):353–64.
    • (2010) Biochim Biophys Acta , vol.1799 , Issue.5-6 , pp. 353-364
    • Ozcan, S.1    Andrali, S.S.2    Cantrell, J.E.3
  • 4
    • 84903767444 scopus 로고    scopus 로고
    • O-GlcNAc profiling: from proteins to proteomes
    • PID: 24593906
    • Ma J, Hart GW. O-GlcNAc profiling: from proteins to proteomes. Clin Proteomics. 2014;11(1):8. doi:10.1186/1559-0275-11-8.
    • (2014) Clin Proteomics , vol.11 , Issue.1 , pp. 8
    • Ma, J.1    Hart, G.W.2
  • 5
    • 84880648662 scopus 로고    scopus 로고
    • O-GlcNAc cycling: a link between metabolism and chronic disease
    • COI: 1:CAS:528:DC%2BC3sXhsVSqtLvF, PID: 23642195
    • Bond MR, Hanover JA. O-GlcNAc cycling: a link between metabolism and chronic disease. Annu Rev Nutr. 2013;33:205–29.
    • (2013) Annu Rev Nutr , vol.33 , pp. 205-229
    • Bond, M.R.1    Hanover, J.A.2
  • 7
    • 80052068559 scopus 로고    scopus 로고
    • O-GlcNAc signalling: implications for cancer cell biology
    • COI: 1:CAS:528:DC%2BC3MXhtVehs73E, PID: 21850036
    • Slawson C, Hart GW. O-GlcNAc signalling: implications for cancer cell biology. Nat Rev Cancer. 2011;11(9):678–84.
    • (2011) Nat Rev Cancer , vol.11 , Issue.9 , pp. 678-684
    • Slawson, C.1    Hart, G.W.2
  • 8
    • 84885315910 scopus 로고    scopus 로고
    • O-GlcNAc in cancer biology
    • COI: 1:CAS:528:DC%2BC3sXhtVOisr3P, PID: 23836420
    • Ma Z, Vosseller K. O-GlcNAc in cancer biology. Amino Acids. 2013;45(4):719–33.
    • (2013) Amino Acids , vol.45 , Issue.4 , pp. 719-733
    • Ma, Z.1    Vosseller, K.2
  • 9
    • 84897566671 scopus 로고    scopus 로고
    • Regulation of cancer metabolism by O-GlcNAcylation
    • PID: 24323367
    • Li Z, Yi W. Regulation of cancer metabolism by O-GlcNAcylation. Glycoconj J. 2013;31(3):185–91.
    • (2013) Glycoconj J , vol.31 , Issue.3 , pp. 185-191
    • Li, Z.1    Yi, W.2
  • 10
    • 84905216343 scopus 로고    scopus 로고
    • O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41
    • COI: 1:CAS:528:DC%2BC2cXht1KrtrfP, PID: 24744147
    • Olivier-Van Stichelen S, Dehennaut V, Buzy A, et al. O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41. FASEB J. 2014;28(8):3325–38.
    • (2014) FASEB J , vol.28 , Issue.8 , pp. 3325-3338
    • Olivier-Van Stichelen, S.1    Dehennaut, V.2    Buzy, A.3
  • 11
    • 84882607514 scopus 로고    scopus 로고
    • O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells
    • COI: 1:CAS:528:DC%2BC3sXht1Ois7%2FO, PID: 23720054
    • Itkonen HM, Minner S, Guldvik IJ, et al. O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells. Cancer Res. 2013;73(16):5277–87.
    • (2013) Cancer Res , vol.73 , Issue.16 , pp. 5277-5287
    • Itkonen, H.M.1    Minner, S.2    Guldvik, I.J.3
  • 12
    • 84877823153 scopus 로고    scopus 로고
    • Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer
    • COI: 1:CAS:528:DC%2BC3sXnslajtbo%3D, PID: 23680148
    • Cooks T, Pateras IS, Tarcic O, et al. Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer. Cancer Cell. 2013;23(5):634–46.
    • (2013) Cancer Cell , vol.23 , Issue.5 , pp. 634-646
    • Cooks, T.1    Pateras, I.S.2    Tarcic, O.3
  • 13
    • 84856693441 scopus 로고    scopus 로고
    • Mutant p53 protein, master regulator of human malignancies: a report on the Fifth Mutant p53 Workshop
    • COI: 1:STN:280:DC%2BC38%2FmsFOhsg%3D%3D, PID: 22095277
    • Blandino G, Deppert W, Hainaut P, et al. Mutant p53 protein, master regulator of human malignancies: a report on the Fifth Mutant p53 Workshop. Cell Death Differ. 2012;19(1):180–3.
    • (2012) Cell Death Differ , vol.19 , Issue.1 , pp. 180-183
    • Blandino, G.1    Deppert, W.2    Hainaut, P.3
  • 14
    • 84878225772 scopus 로고    scopus 로고
    • Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells
    • COI: 1:CAS:528:DC%2BC3sXot1Wjsbk%3D, PID: 23592772
    • Ma Z, Vocadlo DJ, Vosseller K. Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells. J Biol Chem. 2013;288(21):15121–30.
    • (2013) J Biol Chem , vol.288 , Issue.21 , pp. 15121-15130
    • Ma, Z.1    Vocadlo, D.J.2    Vosseller, K.3
  • 15
    • 62549161375 scopus 로고    scopus 로고
    • Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification
    • COI: 1:CAS:528:DC%2BD1MXivF2jtro%3D, PID: 19202066
    • Kawauchi K, Araki K, Tobiume K, Tanaka N. Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification. Proc Natl Acad Sci USA. 2009;106(9):3431–6.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.9 , pp. 3431-3436
    • Kawauchi, K.1    Araki, K.2    Tobiume, K.3    Tanaka, N.4
  • 16
    • 77952429792 scopus 로고    scopus 로고
    • Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
    • COI: 1:CAS:528:DC%2BC3cXisFOkt7s%3D, PID: 20190804
    • Caldwell SA, Jackson SR, Shahriari KS, et al. Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1. Oncogene. 2010;29(19):2831–42.
    • (2010) Oncogene , vol.29 , Issue.19 , pp. 2831-2842
    • Caldwell, S.A.1    Jackson, S.R.2    Shahriari, K.S.3
  • 17
    • 77955401818 scopus 로고    scopus 로고
    • GlcNAcylation plays an essential role in breast cancer metastasis
    • COI: 1:CAS:528:DC%2BC3cXpsVCnurs%3D, PID: 20610629
    • Gu Y, Mi W, Ge Y, et al. GlcNAcylation plays an essential role in breast cancer metastasis. Cancer Res. 2010;70(15):6344–51.
    • (2010) Cancer Res , vol.70 , Issue.15 , pp. 6344-6351
    • Gu, Y.1    Mi, W.2    Ge, Y.3
  • 18
    • 78449288408 scopus 로고    scopus 로고
    • Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition
    • COI: 1:CAS:528:DC%2BC3cXhtlSgurzJ, PID: 20959806
    • Park SY, Kim HS, Kim NH, et al. Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition. EMBO J. 2010;29(22):3787–96.
    • (2010) EMBO J , vol.29 , Issue.22 , pp. 3787-3796
    • Park, S.Y.1    Kim, H.S.2    Kim, N.H.3
  • 19
    • 84859484538 scopus 로고    scopus 로고
    • Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis
    • COI: 1:CAS:528:DC%2BC38XkvVWlsLs%3D, PID: 22275356
    • Lynch TP, Ferrer CM, Jackson SR, Shahriari KS, Vosseller K, Reginato MJ. Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis. J Biol Chem. 2012;287(14):11070–81.
    • (2012) J Biol Chem , vol.287 , Issue.14 , pp. 11070-11081
    • Lynch, T.P.1    Ferrer, C.M.2    Jackson, S.R.3    Shahriari, K.S.4    Vosseller, K.5    Reginato, M.J.6
  • 20
    • 84864766367 scopus 로고    scopus 로고
    • O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation
    • COI: 1:CAS:528:DC%2BC38XmsF2hsL0%3D, PID: 21461968
    • Zhu Q, Zhou L, Yang Z, et al. O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation. Med Oncol. 2012;29(2):985–93.
    • (2012) Med Oncol , vol.29 , Issue.2 , pp. 985-993
    • Zhu, Q.1    Zhou, L.2    Yang, Z.3
  • 21
    • 84894076239 scopus 로고    scopus 로고
    • Overexpression of O-GlcNAc by prostate cancer cells is significantly associated with poor prognosis of patients
    • COI: 1:CAS:528:DC%2BC2cXpt1Wr, PID: 24366413
    • Kamigaito T, Okaneya T, Kawakubo M, Shimojo H, Nishizawa O, Nakayama J. Overexpression of O-GlcNAc by prostate cancer cells is significantly associated with poor prognosis of patients. Prostate Cancer Prostatic Dis. 2014;17(1):18–22.
    • (2014) Prostate Cancer Prostatic Dis , vol.17 , Issue.1 , pp. 18-22
    • Kamigaito, T.1    Okaneya, T.2    Kawakubo, M.3    Shimojo, H.4    Nishizawa, O.5    Nakayama, J.6
  • 22
    • 84890934219 scopus 로고    scopus 로고
    • O-GlcNAcylation of cofilin promotes breast cancer cell invasion
    • COI: 1:CAS:528:DC%2BC3sXhvFymurvN, PID: 24214978
    • Huang X, Pan Q, Sun D, et al. O-GlcNAcylation of cofilin promotes breast cancer cell invasion. J Biol Chem. 2013;288(51):36418–25.
    • (2013) J Biol Chem , vol.288 , Issue.51 , pp. 36418-36425
    • Huang, X.1    Pan, Q.2    Sun, D.3
  • 23
    • 84892396362 scopus 로고    scopus 로고
    • Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer
    • COI: 1:CAS:528:DC%2BC3sXhvFens7vI, PID: 24126823
    • Phueaouan T, Chaiyawat P, Netsirisawan P, et al. Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer. Oncol Rep. 2013;30(6):2929–36.
    • (2013) Oncol Rep , vol.30 , Issue.6 , pp. 2929-2936
    • Phueaouan, T.1    Chaiyawat, P.2    Netsirisawan, P.3
  • 24
    • 84863642965 scopus 로고    scopus 로고
    • Prediction of bladder cancer based on urinary content of MGEA5 and OGT mRNA level
    • COI: 1:CAS:528:DC%2BC38XhtFSnsr7F, PID: 22783592
    • Rozanski W, Krzeslak A, Forma E, et al. Prediction of bladder cancer based on urinary content of MGEA5 and OGT mRNA level. Clin Lab. 2012;58(5–6):579–83.
    • (2012) Clin Lab , vol.58 , Issue.5-6 , pp. 579-583
    • Rozanski, W.1    Krzeslak, A.2    Forma, E.3
  • 25
    • 84865276011 scopus 로고    scopus 로고
    • O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl-β-D-glucosaminidase silencing on cell phenotype and transcriptome
    • COI: 1:CAS:528:DC%2BC38Xht1Wrs7vL, PID: 22730328
    • Yehezkel G, Cohen L, Kliger A, Manor E, Khalaila I. O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl-β-D-glucosaminidase silencing on cell phenotype and transcriptome. J Biol Chem. 2012;287(34):28755–69.
    • (2012) J Biol Chem , vol.287 , Issue.34 , pp. 28755-28769
    • Yehezkel, G.1    Cohen, L.2    Kliger, A.3    Manor, E.4    Khalaila, I.5
  • 26
    • 79751525993 scopus 로고    scopus 로고
    • O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy
    • COI: 1:CAS:528:DC%2BC3MXit1yntL4%3D, PID: 21255644
    • Mi W, Gu Y, Han C, et al. O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy. Biochim Biophys Acta. 2011;1812(4):514–9.
    • (2011) Biochim Biophys Acta , vol.1812 , Issue.4 , pp. 514-519
    • Mi, W.1    Gu, Y.2    Han, C.3
  • 27
    • 84857126294 scopus 로고    scopus 로고
    • Expression of genes encoding for enzymes associated with O-GlcNAcylation in endometrial carcinomas: clinicopathologic correlations
    • PID: 22384635
    • Krześlak A, Wójcik-Krowiranda K, Forma E, Bieńkiewicz A, Bryś M. Expression of genes encoding for enzymes associated with O-GlcNAcylation in endometrial carcinomas: clinicopathologic correlations. Ginekol Pol. 2012;83(1):22–6.
    • (2012) Ginekol Pol , vol.83 , Issue.1 , pp. 22-26
    • Krześlak, A.1    Wójcik-Krowiranda, K.2    Forma, E.3    Bieńkiewicz, A.4    Bryś, M.5
  • 28
    • 0035964998 scopus 로고    scopus 로고
    • Increased N-acetyl-beta-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins
    • COI: 1:CAS:528:DC%2BD3MXmvVKku7s%3D, PID: 11566258
    • Slawson C, Pidala J, Potter R. Increased N-acetyl-beta-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins. Biochim Biophys Acta. 2001;1537(2):147–57.
    • (2001) Biochim Biophys Acta , vol.1537 , Issue.2 , pp. 147-157
    • Slawson, C.1    Pidala, J.2    Potter, R.3
  • 29
    • 77954818058 scopus 로고    scopus 로고
    • The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM
    • PID: 20180029
    • Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol. 2010;17:1471–4.
    • (2010) Ann Surg Oncol , vol.17 , pp. 1471-1474
    • Edge, S.B.1    Compton, C.C.2
  • 30
    • 34347403941 scopus 로고    scopus 로고
    • Tumor front grading in prediction of survival and lymph node metastases in patients with laryngeal carcinoma
    • COI: 1:STN:280:DC%2BD2s7lslKksg%3D%3D, PID: 17357309
    • Starska K, Kulig A, Lukomski M. Tumor front grading in prediction of survival and lymph node metastases in patients with laryngeal carcinoma. Adv Med Sci. 2006;51:200–4.
    • (2006) Adv Med Sci , vol.51 , pp. 200-204
    • Starska, K.1    Kulig, A.2    Lukomski, M.3
  • 31
    • 84880627384 scopus 로고    scopus 로고
    • Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer
    • COI: 1:CAS:528:DC%2BC3sXovVSrt7o%3D, PID: 23576270
    • Champattanachai V, Netsirisawan P, Chaiyawat P, et al. Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer. Proteomics. 2013;13(14):2088–99.
    • (2013) Proteomics , vol.13 , Issue.14 , pp. 2088-2099
    • Champattanachai, V.1    Netsirisawan, P.2    Chaiyawat, P.3
  • 32
    • 84874077524 scopus 로고    scopus 로고
    • Overexpression of O-GlcNAc-transferase associates with aggressiveness of mass-forming cholangiocarcinoma
    • PID: 23480751
    • Phoomak C, Silsirivanit A, Wongkham C, Sripa B, Puapairoj A, Wongkham S. Overexpression of O-GlcNAc-transferase associates with aggressiveness of mass-forming cholangiocarcinoma. Asian Pac J Cancer Prev. 2012;13(Suppl):101–5.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 101-105
    • Phoomak, C.1    Silsirivanit, A.2    Wongkham, C.3    Sripa, B.4    Puapairoj, A.5    Wongkham, S.6
  • 33
    • 84872263925 scopus 로고    scopus 로고
    • O-GlcNAc processing enzymes: catalytic mechanisms, substrate specificity, and enzyme regulation
    • COI: 1:CAS:528:DC%2BC38Xhs1Gkt7zJ, PID: 23146438
    • Vocadlo DJ. O-GlcNAc processing enzymes: catalytic mechanisms, substrate specificity, and enzyme regulation. Curr Opin Chem Biol. 2012;16(5–6):488–97.
    • (2012) Curr Opin Chem Biol , vol.16 , Issue.5-6 , pp. 488-497
    • Vocadlo, D.J.1
  • 34
    • 65649143861 scopus 로고    scopus 로고
    • Enzymatic characterization and inhibition of the nuclear variant of human O-GlcNAcase
    • COI: 1:CAS:528:DC%2BD1MXmtlKksLw%3D, PID: 19423084
    • Macauley MS, Vocadlo DJ. Enzymatic characterization and inhibition of the nuclear variant of human O-GlcNAcase. Carbohydr Res. 2009;344(9):1079–84.
    • (2009) Carbohydr Res , vol.344 , Issue.9 , pp. 1079-1084
    • Macauley, M.S.1    Vocadlo, D.J.2
  • 35
    • 79961138782 scopus 로고    scopus 로고
    • A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome
    • COI: 1:CAS:528:DC%2BC3MXhtlWitbbF, PID: 21807949
    • Keembiyehetty CN, Krzeslak A, Love DC, Hanover JA. A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome. J Cell Sci. 2011;124(16):2851–60.
    • (2011) J Cell Sci , vol.124 , Issue.16 , pp. 2851-2860
    • Keembiyehetty, C.N.1    Krzeslak, A.2    Love, D.C.3    Hanover, J.A.4
  • 36
    • 33646890020 scopus 로고    scopus 로고
    • Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development
    • COI: 1:CAS:528:DC%2BD28XkvVSrs7Y%3D, PID: 16505006
    • Whisenhunt TR, Yang X, Bowe DB, Paterson AJ, Van Tine BA, Kudlow JE. Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development. Glycobiology. 2006;16(6):551–63.
    • (2006) Glycobiology , vol.16 , Issue.6 , pp. 551-563
    • Whisenhunt, T.R.1    Yang, X.2    Bowe, D.B.3    Paterson, A.J.4    Van Tine, B.A.5    Kudlow, J.E.6
  • 37
    • 0030959555 scopus 로고    scopus 로고
    • Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats
    • COI: 1:CAS:528:DyaK2sXisVGqs7s%3D, PID: 9083067
    • Kreppel LK, Blomberg MA, Hart GW. Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats. J Biol Chem. 1997;272(14):9308–15.
    • (1997) J Biol Chem , vol.272 , Issue.14 , pp. 9308-9315
    • Kreppel, L.K.1    Blomberg, M.A.2    Hart, G.W.3
  • 38
    • 84888321789 scopus 로고    scopus 로고
    • Preclinical evaluation of the novel monoclonal antibody H6-11 for prostate cancer imaging
    • COI: 1:CAS:528:DC%2BC3sXhtlSgsbrJ, PID: 23964702
    • Jin H, Xu M, Padakanti PK, Liu Y, Lapi S, Tu Z. Preclinical evaluation of the novel monoclonal antibody H6-11 for prostate cancer imaging. Mol Pharm. 2013;10(10):3655–64.
    • (2013) Mol Pharm , vol.10 , Issue.10 , pp. 3655-3664
    • Jin, H.1    Xu, M.2    Padakanti, P.K.3    Liu, Y.4    Lapi, S.5    Tu, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.