메뉴 건너뛰기




Volumn 309, Issue 8, 2015, Pages G648-G661

Phenotypic divergence in two lines of L-Fabp-/- mice reflects substrain differences and environmental modifiers

Author keywords

C57BL 6 substrain; Divergent phenotypes; Fatty acid binding protein; Gene knockout; Jax mice; Lipid trafficking; Microbiome; Triglyceride

Indexed keywords

ADENOVIRUS VECTOR; ANTIBIOTIC AGENT; ESSENTIAL FATTY ACID; FATTY ACID BINDING PROTEIN; GENOMIC DNA; MESSENGER RNA; SATURATED FATTY ACID; THEOBROMA OIL; TRIACYLGLYCEROL; ANTIINFECTIVE AGENT; FABP1 PROTEIN, MOUSE; FAT INTAKE;

EID: 84945186499     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00170.2015     Document Type: Article
Times cited : (17)

References (39)
  • 1
    • 84885434881 scopus 로고    scopus 로고
    • Genomic structure and genetic drift in C57BL/6 congenic metabolic mutant mice
    • Almodovar AJ, Luther RJ, Stonebrook CL, Wood PA. Genomic structure and genetic drift in C57BL/6 congenic metabolic mutant mice. Mol Genet Metab 110: 396-400, 2013.
    • (2013) Mol Genet Metab , vol.110 , pp. 396-400
    • Almodovar, A.J.1    Luther, R.J.2    Stonebrook, C.L.3    Wood, P.A.4
  • 3
    • 77949262245 scopus 로고    scopus 로고
    • High dietary fat exacerbates weight gain and obesity in female liver fatty acid binding protein gene-ablated mice
    • Atshaves BP, McIntosh AL, Storey SM, Landrock KK, Kier AB, Schroeder F. High dietary fat exacerbates weight gain and obesity in female liver fatty acid binding protein gene-ablated mice. Lipids 45: 97-110, 2010.
    • (2010) Lipids , vol.45 , pp. 97-110
    • Atshaves, B.P.1    McIntosh, A.L.2    Storey, S.M.3    Landrock, K.K.4    Kier, A.B.5    Schroeder, F.6
  • 4
    • 3843053654 scopus 로고    scopus 로고
    • Liver fatty acid-binding protein gene ablation inhibits branched-chain fatty acid metabolism in cultured primary hepatocytes
    • Atshaves BP, McIntosh AM, Lyuksyutova OI, Zipfel W, Webb WW, Schroeder F. Liver fatty acid-binding protein gene ablation inhibits branched-chain fatty acid metabolism in cultured primary hepatocytes. J Biol Chem 279: 30954-30965, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 30954-30965
    • Atshaves, B.P.1    McIntosh, A.M.2    Lyuksyutova, O.I.3    Zipfel, W.4    Webb, W.W.5    Schroeder, F.6
  • 5
    • 79959391575 scopus 로고    scopus 로고
    • Mispairing C57BL/6 substrains of genetically engineered mice and wild-type controls can lead to confounding results as it did in studies of JNK2 in acetaminophen and concanavalin A liver injury
    • Bourdi M, Davies JS, Pohl LR. Mispairing C57BL/6 substrains of genetically engineered mice and wild-type controls can lead to confounding results as it did in studies of JNK2 in acetaminophen and concanavalin A liver injury. Chem Res Toxicol 24: 794-796, 2011.
    • (2011) Chem Res Toxicol , vol.24 , pp. 794-796
    • Bourdi, M.1    Davies, J.S.2    Pohl, L.R.3
  • 6
    • 0023626080 scopus 로고
    • Essential fatty acid deficiency during pregnancy in the rat: Influence of dietary carbohydrates
    • Cardot P, Chambaz J, Thomas G, Rayssiguier Y, Bereziat G. Essential fatty acid deficiency during pregnancy in the rat: influence of dietary carbohydrates. J Nutr 117: 1504-1513, 1987.
    • (1987) J Nutr , vol.117 , pp. 1504-1513
    • Cardot, P.1    Chambaz, J.2    Thomas, G.3    Rayssiguier, Y.4    Bereziat, G.5
  • 7
    • 84879126852 scopus 로고    scopus 로고
    • Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease
    • Chen A, Tang Y, Davis V, Hsu FF, Kennedy SM, Song H, Turk J, Brunt EM, Newberry EP, Davidson NO. Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease. Hepatology 57: 2202-2212, 2013.
    • (2013) Hepatology , vol.57 , pp. 2202-2212
    • Chen, A.1    Tang, Y.2    Davis, V.3    Hsu, F.F.4    Kennedy, S.M.5    Song, H.6    Turk, J.7    Brunt, E.M.8    Newberry, E.P.9    Davidson, N.O.10
  • 8
    • 0015803897 scopus 로고
    • Fat absorption in essential fatty acid deficiency: A model experimental approach to studies of the mechanism of fat malabsorption of unknown etiology
    • Clark SB, Ekkers TE, Singh A, Balint JA, Holt PR, Rodgers JB Jr. Fat absorption in essential fatty acid deficiency: a model experimental approach to studies of the mechanism of fat malabsorption of unknown etiology. J Lipid Res 14: 581-588, 1973.
    • (1973) J Lipid Res , vol.14 , pp. 581-588
    • Clark, S.B.1    Ekkers, T.E.2    Singh, A.3    Balint, J.A.4    Holt, P.R.5    Rodgers, J.B.6
  • 9
    • 1442314719 scopus 로고    scopus 로고
    • Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPAR_ in fasting mice
    • Erol E, Kumar LS, Cline GW, Shulman GI, Kelly DP, Binas B. Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPAR_ in fasting mice. FASEB J 18: 347-349, 2004.
    • (2004) FASEB J , vol.18 , pp. 347-349
    • Erol, E.1    Kumar, L.S.2    Cline, G.W.3    Shulman, G.I.4    Kelly, D.P.5    Binas, B.6
  • 10
    • 33747032052 scopus 로고    scopus 로고
    • Deletion of nicotinamide nucleotide transhydrogenase: A new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice
    • Freeman HC, Hugill A, Dear NT, Ashcroft FM, Cox RD. Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice. Diabetes 55: 2153-2156, 2006.
    • (2006) Diabetes , vol.55 , pp. 2153-2156
    • Freeman, H.C.1    Hugill, A.2    Dear, N.T.3    Ashcroft, F.M.4    Cox, R.D.5
  • 11
    • 84922782211 scopus 로고    scopus 로고
    • Enterocyte fatty acid-binding proteins (FABPs): Different functions of liver and intestinal FABPs in the intestine
    • Gajda AM, Storch J. Enterocyte fatty acid-binding proteins (FABPs): different functions of liver and intestinal FABPs in the intestine. Prostaglandins Leukot Essent Fatty Acids 93: 9-16, 2015.
    • (2015) Prostaglandins Leukot Essent Fatty Acids , vol.93 , pp. 9-16
    • Gajda, A.M.1    Storch, J.2
  • 12
    • 84886909998 scopus 로고    scopus 로고
    • Direct comparison of mice null for liver or intestinal fatty acid-binding proteins reveals highly divergent phenotypic responses to high fat feeding
    • Gajda AM, Zhou YX, Agellon LB, Fried SK, Kodukula S, Fortson W, Patel K, Storch J. Direct comparison of mice null for liver or intestinal fatty acid-binding proteins reveals highly divergent phenotypic responses to high fat feeding. J Biol Chem 288: 30330-30344, 2013.
    • (2013) J Biol Chem , vol.288 , pp. 30330-30344
    • Gajda, A.M.1    Zhou, Y.X.2    Agellon, L.B.3    Fried, S.K.4    Kodukula, S.5    Fortson, W.6    Patel, K.7    Storch, J.8
  • 16
    • 84884212935 scopus 로고    scopus 로고
    • The effect of varying ratios of docosahexaenoic acid and arachidonic acid in the prevention and reversal of biochemical essential fatty acid deficiency in a murine model
    • Le HD, Fallon EM, Kalish BT, de Meijer VE, Meisel JA, Gura KM, Nose V, Pan AH, Bistrian BR, Puder M. The effect of varying ratios of docosahexaenoic acid and arachidonic acid in the prevention and reversal of biochemical essential fatty acid deficiency in a murine model. Metabolism 62: 499-508, 2013.
    • (2013) Metabolism , vol.62 , pp. 499-508
    • Le, H.D.1    Fallon, E.M.2    Kalish, B.T.3    De Meijer, V.E.4    Meisel, J.A.5    Gura, K.M.6    Nose, V.7    Pan, A.H.8    Bistrian, B.R.9    Puder, M.10
  • 19
    • 54749090896 scopus 로고    scopus 로고
    • Liver fatty acid-binding protein gene-ablated female mice exhibit increased age-dependent obesity
    • Martin GG, Atshaves BP, McIntosh AL, Mackie JT, Kier AB, Schroeder F. Liver fatty acid-binding protein gene-ablated female mice exhibit increased age-dependent obesity. J Nutr 138: 1859-1865, 2008.
    • (2008) J Nutr , vol.138 , pp. 1859-1865
    • Martin, G.G.1    Atshaves, B.P.2    McIntosh, A.L.3    Mackie, J.T.4    Kier, A.B.5    Schroeder, F.6
  • 20
    • 27744551398 scopus 로고    scopus 로고
    • Liver fatty-acid-binding protein (L-FABP) gene ablation alters liver bile acid metabolism in male mice
    • Martin GG, Atshaves BP, McIntosh AL, Mackie JT, Kier AB, Schroeder F. Liver fatty-acid-binding protein (L-FABP) gene ablation alters liver bile acid metabolism in male mice. Biochem J 391: 549-560, 2005.
    • (2005) Biochem J , vol.391 , pp. 549-560
    • Martin, G.G.1    Atshaves, B.P.2    McIntosh, A.L.3    Mackie, J.T.4    Kier, A.B.5    Schroeder, F.6
  • 22
    • 0038498152 scopus 로고    scopus 로고
    • Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene
    • Martin GG, Danneberg H, Kumar LS, Atshaves BP, Erol E, Bader M, Schroeder F, Binas B. Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene. J Biol Chem 278: 21429-21438, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 21429-21438
    • Martin, G.G.1    Danneberg, H.2    Kumar, L.S.3    Atshaves, B.P.4    Erol, E.5    Bader, M.6    Schroeder, F.7    Binas, B.8
  • 23
    • 0141594833 scopus 로고    scopus 로고
    • Ablation of the liver fatty acid binding protein gene decreases fatty acyl CoA binding capacity and alters fatty acyl CoA pool distribution in mouse liver
    • Martin GG, Huang H, Atshaves BP, Binas B, Schroeder F. Ablation of the liver fatty acid binding protein gene decreases fatty acyl CoA binding capacity and alters fatty acyl CoA pool distribution in mouse liver. Biochemistry 42: 11520-11532, 2003.
    • (2003) Biochemistry , vol.42 , pp. 11520-11532
    • Martin, G.G.1    Huang, H.2    Atshaves, B.P.3    Binas, B.4    Schroeder, F.5
  • 27
    • 67349138642 scopus 로고    scopus 로고
    • Diet-induced alterations in intestinal and extrahepatic lipid metabolism in liver fatty acid binding protein knockout mice
    • Newberry EP, Kennedy SM, Xie Y, Luo J, Davidson NO. Diet-induced alterations in intestinal and extrahepatic lipid metabolism in liver fatty acid binding protein knockout mice. Mol Cell Biochem 326: 79-86, 2009.
    • (2009) Mol Cell Biochem , vol.326 , pp. 79-86
    • Newberry, E.P.1    Kennedy, S.M.2    Xie, Y.3    Luo, J.4    Davidson, N.O.5
  • 29
    • 0347065337 scopus 로고    scopus 로고
    • Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acidbinding protein gene
    • Newberry EP, Xie Y, Kennedy S, Han X, Buhman KK, Luo J, Gross RW, Davidson NO. Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acidbinding protein gene. J Biol Chem 278: 51664-51672, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 51664-51672
    • Newberry, E.P.1    Xie, Y.2    Kennedy, S.3    Han, X.4    Buhman, K.K.5    Luo, J.6    Gross, R.W.7    Davidson, N.O.8
  • 30
    • 33750998524 scopus 로고    scopus 로고
    • Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice
    • Newberry EP, Xie Y, Kennedy SM, Luo J, Davidson NO. Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice. Hepatology 44: 1191-1205, 2006.
    • (2006) Hepatology , vol.44 , pp. 1191-1205
    • Newberry, E.P.1    Xie, Y.2    Kennedy, S.M.3    Luo, J.4    Davidson, N.O.5
  • 31
    • 77953513138 scopus 로고    scopus 로고
    • A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ER
    • Siddiqi S, Saleem U, Abumrad NA, Davidson NO, Storch J, Siddiqi SA, Mansbach CM 2nd. A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ER. J Lipid Res 51: 1918-1928, 2010.
    • (2010) J Lipid Res , vol.51 , pp. 1918-1928
    • Siddiqi, S.1    Saleem, U.2    Abumrad, N.A.3    Davidson, N.O.4    Storch, J.5    Siddiqi, S.A.6    Mansbach, C.M.7
  • 33
    • 79961117132 scopus 로고    scopus 로고
    • The human fatty acid-binding protein family: Evolutionary divergences and functions
    • Smathers RL, Petersen DR. The human fatty acid-binding protein family: evolutionary divergences and functions. Hum Genomics 5: 170-191, 2011.
    • (2011) Hum Genomics , vol.5 , pp. 170-191
    • Smathers, R.L.1    Petersen, D.R.2
  • 34
    • 0035789203 scopus 로고    scopus 로고
    • Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
    • Specht CG, Schoepfer R. Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice. BMC Neurosci 2: 11, 2001.
    • (2001) BMC Neurosci , vol.2 , pp. 11
    • Specht, C.G.1    Schoepfer, R.2
  • 35
    • 77958456869 scopus 로고    scopus 로고
    • Tissue-specific functions in the fatty acid-binding protein family
    • Storch J, Thumser AE. Tissue-specific functions in the fatty acid-binding protein family. J Biol Chem 285: 32679-32683, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 32679-32683
    • Storch, J.1    Thumser, A.E.2
  • 36
    • 0023637058 scopus 로고
    • Impaired platelet aggregation and thromboxane generation in essential fatty acid-deficient rats
    • Takahashi R, Manku MS, Horrobin DF. Impaired platelet aggregation and thromboxane generation in essential fatty acid-deficient rats. J Nutr 117: 1520-1526, 1987.
    • (1987) J Nutr , vol.117 , pp. 1520-1526
    • Takahashi, R.1    Manku, M.S.2    Horrobin, D.F.3
  • 39
    • 67649675014 scopus 로고    scopus 로고
    • Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice
    • Xie Y, Newberry EP, Kennedy SM, Luo J, Davidson NO. Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice. J Lipid Res 50: 977-987, 2009.
    • (2009) J Lipid Res , vol.50 , pp. 977-987
    • Xie, Y.1    Newberry, E.P.2    Kennedy, S.M.3    Luo, J.4    Davidson, N.O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.