Synthesis of ((3R,6R)-6-Methylpiperidin-3-yl)methanol via Biocatalytic Transamination and Crystallization-Induced Dynamic Resolution

Organic Process Research and Development

Volumn 19, Issue 10, 2015, Pages 1418-1423

  Chung, John Y L ^a   Marcune, Benjamin ^a   Strotman, Hallena R ^a   Petrova, Rositza I ^a   Moore, Jeffrey C ^a   Dormer, Peter G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; KETONES; METHANOL; MIXTURES;

ACID MIXTURES; ASYMMETRIC SYNTHESIS; CRYSTALLIZATION-INDUCED DYNAMIC RESOLUTIONS; DIETHYL MALONATES; KEY OPERATIONS; METHYL VINYL KETONES; MICHAEL REACTIONS; RECEPTOR ANTAGONISTS;

SYNTHESIS (CHEMICAL);

EID: 84944736299     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/acs.oprd.5b00259     Document Type: Article

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