Bone marrow stromal cells protect acute myeloid leukemia cells from anti-CD44 therapy partly through regulating PI3K/Akt-p27Kip1 axis

Molecular Carcinogenesis

Volumn 54, Issue 12, 2015, Pages 1678-1685

  Chen, Ping ^a   Huang, Huifang ^a   Wu, Juanying ^a   Lu, Rong ^a   Wu, Yong ^a   Jiang, Xi ^a   Yuan, Qin ^a   Chen, Yuanzhong ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

A3D8; Acute myeloid leukemia; Bone marrow stroma; P27Kip1; PI3K Akt

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY A3D8; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; CD44 PROTEIN, HUMAN; CDKN1B PROTEIN, HUMAN; HERMES ANTIGEN;

ACUTE MYELOBLASTIC LEUKEMIA; ADULT; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BONE MARROW STROMA CELL; CANCER RESISTANCE; CELL ADHESION; COCULTURE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; LEUKEMIA CELL; MALE; MESENCHYMAL STEM CELL; MIDDLE AGED; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE; DRUG EFFECTS; DRUG RESISTANCE; IMMUNOLOGY; LEUKEMIA, MYELOID, ACUTE; MESENCHYMAL STROMA CELL; METABOLISM; TUMOR CELL LINE;

ADULT; ANTIBODIES, MONOCLONAL; ANTIGENS, CD44; CELL LINE, TUMOR; COCULTURE TECHNIQUES; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOPLASM; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84944630038     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22239     Document Type: Article

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