A multicenter, randomized, double-blind, placebo-controlled trial to test efficacy and safety of magnetic resonance imaging-based thrombolysis in wake-up stroke (WAKE-UP)

International Journal of Stroke

Volumn 9, Issue 6, 2014, Pages 829-836

  Thomalla, Götz ^a   Fiebach, Jochen B ^b   Østergaard, Leif ^c   Pedraza, Salvador ^d   Thijs, Vincent ^e,f,g   Nighoghossian, Norbert ^h   Roy, Pascal ^h   Muir, Keith W ⁱ   Ebinger, Martin ^b   Cheng, Bastian ^a   Galinovic, Ivana ^b   Cho, Tae Hee ^h   Puig, Josep ^d   Boutitie, Florent ^h   Simonsen, Claus Z ^c   Endres, Matthias ^b   Fiehler, Jens ^a   Gerloff, Christian ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d HOSPITAL JOSEP TRUETA   (Spain)

^e UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^f DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^g UNIVERSITY OF LEUVEN   (Belgium)

^h HOSPICES CIVILS DE LYON   (France)

ⁱ UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Acute ischemic stroke; Clinical trials; Diffusion weighted imaging; Fluid attenuated inversion recovery imaging; Protocols; Thrombolysis

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR; FIBRINOLYTIC AGENT; RECOMBINANT PROTEIN;

ARTICLE; BLOOD CLOT LYSIS; CEREBROVASCULAR ACCIDENT; HUMAN; MORTALITY; MULTICENTER STUDY (TOPIC); NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PATIENT SAFETY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RANKIN SCALE; THERAPY EFFECT; TREATMENT OUTCOME; ADVERSE EFFECTS; BRAIN ISCHEMIA; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DOUBLE BLIND PROCEDURE; FIBRINOLYTIC THERAPY; IMAGE PROCESSING; MULTICENTER STUDY; PATHOPHYSIOLOGY; PATIENT SELECTION; PROCEDURES; SAMPLE SIZE; SLEEP; STROKE; TIME;

BRAIN ISCHEMIA; CLINICAL PROTOCOLS; DIFFUSION MAGNETIC RESONANCE IMAGING; DOUBLE-BLIND METHOD; FIBRINOLYTIC AGENTS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; PATIENT SELECTION; RECOMBINANT PROTEINS; SAMPLE SIZE; SLEEP; STROKE; THROMBOLYTIC THERAPY; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME;

EID: 84904577807     PISSN: 17474930     EISSN: 17474949     Source Type: Journal    
DOI: 10.1111/ijs.12011     Document Type: Article

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