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Volumn 6, Issue 29, 2015, Pages 26946-26959

Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma

Author keywords

Annexin A2 (ANXA2); Chemotherapy; Epithelial mesenchymal transition (EMT); Nasopharyngeal carcinoma (NPC); Radiotherapy

Indexed keywords

CISPLATIN; DOCETAXEL; FLUOROURACIL; LIPOCORTIN 2; NERVE CELL ADHESION MOLECULE; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; VINCRISTINE; ANTINEOPLASTIC AGENT; ANXA2 PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 84944459557     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4521     Document Type: Article
Times cited : (43)

References (53)
  • 1
    • 79960055303 scopus 로고    scopus 로고
    • Can Global Variation of Nasopharynx Cancer Be Retrieved from the Combined Analyses of IARC Cancer Information (CIN) Databases?
    • Sun X, Tong LP, Wang YT, Wu YX, Sheng HS, Lu LJ, Wang W. Can Global Variation of Nasopharynx Cancer Be Retrieved from the Combined Analyses of IARC Cancer Information (CIN) Databases? PloS one. 2011; 6:e22039.
    • (2011) PloS one. , vol.6
    • Sun, X.1    Tong, L.P.2    Wang, Y.T.3    Wu, Y.X.4    Sheng, H.S.5    Lu, L.J.6    Wang, W.7
  • 2
    • 33846705453 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma: molecular biomarker discovery and progress
    • Cho WC. Nasopharyngeal carcinoma: molecular biomarker discovery and progress. Mol cancer. 2007; 6:1.
    • (2007) Mol cancer. , vol.6 , pp. 1
    • Cho, W.C.1
  • 3
    • 0030221501 scopus 로고    scopus 로고
    • Epstein-Barr virus infection and the pathogenesis of nasopharyngeal carcinoma: Viral gene expression, tumour cell phenotype, and the role of the lymphoid stroma
    • Niedobitek G, Agathanggelou A, Nicholls JM. Epstein-Barr virus infection and the pathogenesis of nasopharyngeal carcinoma: Viral gene expression, tumour cell phenotype, and the role of the lymphoid stroma. Semin Cancer Biol. 1996; 7:165-174.
    • (1996) Semin Cancer Biol. , vol.7 , pp. 165-174
    • Niedobitek, G.1    Agathanggelou, A.2    Nicholls, J.M.3
  • 5
    • 10844236518 scopus 로고    scopus 로고
    • Recent perspectives in the role of chemotherapy in the management of advanced nasopharyngeal carcinoma
    • Ma BB, Chan AT. Recent perspectives in the role of chemotherapy in the management of advanced nasopharyngeal carcinoma. Cancer. 2005; 103:22-31.
    • (2005) Cancer. , vol.103 , pp. 22-31
    • Ma, B.B.1    Chan, A.T.2
  • 6
    • 84863269918 scopus 로고    scopus 로고
    • Effective treatment of metastatic forms of Epstein-Barr virus-associated nasopharyngeal carcinoma with a novel adenovirus-based adoptive immunotherapy
    • Smith C, Tsang J, Beagley L, Chua D, Lee V, Li V, Moss DJ, Coman W, Chan KH, Nicholls J, Kwong D, Khanna R. Effective treatment of metastatic forms of Epstein-Barr virus-associated nasopharyngeal carcinoma with a novel adenovirus-based adoptive immunotherapy. Cancer Res. 2012; 72:1116-1125.
    • (2012) Cancer Res. , vol.72 , pp. 1116-1125
    • Smith, C.1    Tsang, J.2    Beagley, L.3    Chua, D.4    Lee, V.5    Li, V.6    Moss, D.J.7    Coman, W.8    Chan, K.H.9    Nicholls, J.10    Kwong, D.11    Khanna, R.12
  • 7
    • 79960143714 scopus 로고    scopus 로고
    • Immunophenotyping at the time of diagnosis distinguishes two groups of nasopharyngeal carcinoma patients: implications for adoptive immunotherapy
    • Li J, Chen QY, Mo H, Zhang YL, Huang ZF, Zeng YX. Immunophenotyping at the time of diagnosis distinguishes two groups of nasopharyngeal carcinoma patients: implications for adoptive immunotherapy. Int J Biol Sci. 2011; 7:607-617.
    • (2011) Int J Biol Sci. , vol.7 , pp. 607-617
    • Li, J.1    Chen, Q.Y.2    Mo, H.3    Zhang, Y.L.4    Huang, Z.F.5    Zeng, Y.X.6
  • 8
    • 84886945467 scopus 로고    scopus 로고
    • A new approach for cellular immunotherapy of nasopharyngeal carcinoma
    • Smith C, Khanna R. A new approach for cellular immunotherapy of nasopharyngeal carcinoma. Oncoimmunology. 2012; 1:1440-1442.
    • (2012) Oncoimmunology. , vol.1 , pp. 1440-1442
    • Smith, C.1    Khanna, R.2
  • 18
    • 33750812269 scopus 로고    scopus 로고
    • Angiogenesis-associated protein annexin II in breast cancer: selective expression in invasive breast cancer and contribution to tumor invasion and progression
    • Sharma MR, Koltowski L, Ownbey RT, Tuszynski GP, Sharma MC. Angiogenesis-associated protein annexin II in breast cancer: selective expression in invasive breast cancer and contribution to tumor invasion and progression. Exp Mol Pathol. 2006; 81:146-156.
    • (2006) Exp Mol Pathol. , vol.81 , pp. 146-156
    • Sharma, M.R.1    Koltowski, L.2    Ownbey, R.T.3    Tuszynski, G.P.4    Sharma, M.C.5
  • 19
    • 41749085986 scopus 로고    scopus 로고
    • Proteomic comparison of nasopharyngeal cancer cell lines C666-1 and NP69 identifies down-regulation of annexin II and beta2-tubulin for nasopharyngeal carcinoma
    • Chan CM, Wong SC, Lam MY, Hui EP, Chan JK, Lo ES, Cheuk W, Wong MC, Tsao SW, Chan AT. Proteomic comparison of nasopharyngeal cancer cell lines C666-1 and NP69 identifies down-regulation of annexin II and beta2-tubulin for nasopharyngeal carcinoma. Arch Pathol Lab Med. 2008; 132:675-683.
    • (2008) Arch Pathol Lab Med. , vol.132 , pp. 675-683
    • Chan, C.M.1    Wong, S.C.2    Lam, M.Y.3    Hui, E.P.4    Chan, J.K.5    Lo, E.S.6    Cheuk, W.7    Wong, M.C.8    Tsao, S.W.9    Chan, A.T.10
  • 21
  • 22
    • 84922632417 scopus 로고    scopus 로고
    • Annexin A2 in renal cell carcinoma: expression, function, and prognostic significance
    • e11-21
    • Yang SF, Hsu HL, Chao TK, Hsiao CJ, Lin YF, Cheng CW. Annexin A2 in renal cell carcinoma: expression, function, and prognostic significance. Urol Oncol. 2015; 33:22. e11-21.
    • (2015) Urol Oncol. , vol.33 , pp. 22
    • Yang, S.F.1    Hsu, H.L.2    Chao, T.K.3    Hsiao, C.J.4    Lin, Y.F.5    Cheng, C.W.6
  • 23
    • 84920197820 scopus 로고    scopus 로고
    • Overexpression of ANXA2 predicts adverse outcomes of patients with malignant tumors: a systematic review and meta-analysis
    • Liu X, Ma D, Jing X, Wang B, Yang W, Qiu W. Overexpression of ANXA2 predicts adverse outcomes of patients with malignant tumors: a systematic review and meta-analysis. Med Oncol. 2015; 32:392.
    • (2015) Med Oncol. , vol.32 , pp. 392
    • Liu, X.1    Ma, D.2    Jing, X.3    Wang, B.4    Yang, W.5    Qiu, W.6
  • 24
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol. 2006; 7:131-142.
    • (2006) Nat Rev Mol Cell Biol. , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 25
    • 70450198396 scopus 로고    scopus 로고
    • Epithelialmesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelialmesenchymal transitions in development and disease. Cell. 2009; 139:871-890.
    • (2009) Cell. , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 26
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2014; 15:178-196.
    • (2014) Nat Rev Mol Cell Biol. , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 27
  • 29
    • 33751585018 scopus 로고    scopus 로고
    • Annexin2 coating the surface of enlargeosomes is needed for their regulated exocytosis
    • Lorusso A, Covino C, Priori G, Bachi A, Meldolesi J, Chieregatti E. Annexin2 coating the surface of enlargeosomes is needed for their regulated exocytosis. Embo J. 2006; 25:5443-5456.
    • (2006) Embo J. , vol.25 , pp. 5443-5456
    • Lorusso, A.1    Covino, C.2    Priori, G.3    Bachi, A.4    Meldolesi, J.5    Chieregatti, E.6
  • 30
    • 34249035506 scopus 로고    scopus 로고
    • Enlargeosome traffic: exocytosis triggered by various signals is followed by endocytosis, membrane shedding or both
    • Cocucci E, Racchetti G, Podini P, Meldolesi J. Enlargeosome traffic: exocytosis triggered by various signals is followed by endocytosis, membrane shedding or both. Traffic. 2007; 8:742-757.
    • (2007) Traffic. , vol.8 , pp. 742-757
    • Cocucci, E.1    Racchetti, G.2    Podini, P.3    Meldolesi, J.4
  • 31
    • 34948817753 scopus 로고    scopus 로고
    • The Ca2+-dependent exocytosis of enlargeosomes is greatly reinforced by genistein via a non-tyrosine kinase-dependent mechanism
    • Prada I, Cocucci E, Racchetti G, Meldolesi J. The Ca2+-dependent exocytosis of enlargeosomes is greatly reinforced by genistein via a non-tyrosine kinase-dependent mechanism. FEBS letters. 2007; 581:4932-4936.
    • (2007) FEBS letters. , vol.581 , pp. 4932-4936
    • Prada, I.1    Cocucci, E.2    Racchetti, G.3    Meldolesi, J.4
  • 32
    • 84870611322 scopus 로고    scopus 로고
    • Genotoxic agents promote the nuclear accumulation of annexin A2: role of annexin A2 in mitigating DNA damage
    • Madureira PA, Hill R, Lee PW, Waisman DM. Genotoxic agents promote the nuclear accumulation of annexin A2: role of annexin A2 in mitigating DNA damage. PloS one. 2012; 7:e50591.
    • (2012) PloS one. , vol.7
    • Madureira, P.A.1    Hill, R.2    Lee, P.W.3    Waisman, D.M.4
  • 35
    • 56749156112 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 mediates serine 25 phosphorylation and nuclear entry of annexin A2 via PI-PLC-PKCalpha/ PKCbeta pathway
    • Luo W, Yan G, Li L, Wang Z, Liu H, Zhou S, Liu S, Tang M, Yi W, Dong Z, Cao Y. Epstein-Barr virus latent membrane protein 1 mediates serine 25 phosphorylation and nuclear entry of annexin A2 via PI-PLC-PKCalpha/ PKCbeta pathway. Mol Carcinog. 2008; 47:934-946.
    • (2008) Mol Carcinog. , vol.47 , pp. 934-946
    • Luo, W.1    Yan, G.2    Li, L.3    Wang, Z.4    Liu, H.5    Zhou, S.6    Liu, S.7    Tang, M.8    Yi, W.9    Dong, Z.10    Cao, Y.11
  • 36
    • 36949034117 scopus 로고    scopus 로고
    • Mechanisms of disease: the PI3K-Akt-PTEN signaling node-an intercept point for the control of angiogenesis in brain tumors
    • Castellino RC, Durden DL. Mechanisms of disease: the PI3K-Akt-PTEN signaling node-an intercept point for the control of angiogenesis in brain tumors. Nat Clin Pract Neurol. 2007; 3:682-693.
    • (2007) Nat Clin Pract Neurol. , vol.3 , pp. 682-693
    • Castellino, R.C.1    Durden, D.L.2
  • 37
    • 33750890673 scopus 로고    scopus 로고
    • Radiationenhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway
    • Cheng JC, Chou CH, Kuo ML, Hsieh CY. Radiationenhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway. Oncogene. 2006; 25:7009-7018.
    • (2006) Oncogene. , vol.25 , pp. 7009-7018
    • Cheng, J.C.1    Chou, C.H.2    Kuo, M.L.3    Hsieh, C.Y.4
  • 38
    • 78649669332 scopus 로고    scopus 로고
    • Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of survival
    • Kanagasabai R, Karthikeyan K, Vedam K, Qien W, Zhu Q, Ilangovan G. Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of survival. Mol Cancer Res. 2010; 8:1399-1412.
    • (2010) Mol Cancer Res. , vol.8 , pp. 1399-1412
    • Kanagasabai, R.1    Karthikeyan, K.2    Vedam, K.3    Qien, W.4    Zhu, Q.5    Ilangovan, G.6
  • 39
    • 50349099779 scopus 로고    scopus 로고
    • Emerging role for AS160/ TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic
    • Sakamoto K, Holman GD. Emerging role for AS160/ TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic. Am J Physiol Endocrinol Metab. 2008; 295:E29-37.
    • (2008) Am J Physiol Endocrinol Metab. , vol.295 , pp. E29-37
    • Sakamoto, K.1    Holman, G.D.2
  • 40
    • 74049133619 scopus 로고    scopus 로고
    • Subcellular targeting strategies for drug design and delivery
    • Rajendran L, Knolker HJ, Simons K. Subcellular targeting strategies for drug design and delivery. Nat Rev Drug Discov. 2010; 9:29-42.
    • (2010) Nat Rev Drug Discov. , vol.9 , pp. 29-42
    • Rajendran, L.1    Knolker, H.J.2    Simons, K.3
  • 41
    • 27844461512 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways
    • Larue L, Bellacosa A. Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways. Oncogene. 2005; 24:7443-7454.
    • (2005) Oncogene. , vol.24 , pp. 7443-7454
    • Larue, L.1    Bellacosa, A.2
  • 42
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer. 2008; 8:755-768.
    • (2008) Nat Rev Cancer. , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 43
    • 84915749487 scopus 로고    scopus 로고
    • Cancer stem cells-important players in tumor therapy resistance
    • Colak S, Medema JP. Cancer stem cells-important players in tumor therapy resistance. FEBS J. 2014; 281:4779-4791.
    • (2014) FEBS J. , vol.281 , pp. 4779-4791
    • Colak, S.1    Medema, J.P.2
  • 44
    • 84923248130 scopus 로고    scopus 로고
    • A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms
    • Cojoc M, Mabert K, Muders MH, Dubrovska A. A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms. Semin Cancer Biol. 2015; 31:16-27.
    • (2015) Semin Cancer Biol. , vol.31 , pp. 16-27
    • Cojoc, M.1    Mabert, K.2    Muders, M.H.3    Dubrovska, A.4
  • 46
    • 79957846955 scopus 로고    scopus 로고
    • The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells
    • Li H, Gao Q, Guo L, Lu SH. The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. Cancer Biol Ther. 2011; 11:950-958.
    • (2011) Cancer Biol Ther. , vol.11 , pp. 950-958
    • Li, H.1    Gao, Q.2    Guo, L.3    Lu, S.H.4
  • 47
    • 84866555389 scopus 로고    scopus 로고
    • EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like sidepopulation cells in non-small cell lung cancer
    • Singh S, Trevino J, Bora-Singhal N, Coppola D, Haura E, Altiok S, Chellappan SP. EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like sidepopulation cells in non-small cell lung cancer. Mol Cancer. 2012; 11:73.
    • (2012) Mol Cancer. , vol.11 , pp. 73
    • Singh, S.1    Trevino, J.2    Bora-Singhal, N.3    Coppola, D.4    Haura, E.5    Altiok, S.6    Chellappan, S.P.7
  • 48
    • 84875881470 scopus 로고    scopus 로고
    • Activation of protein kinase CK2 attenuates FOXO3a functioning in a PML-dependent manner: implications in human prostate cancer
    • Chatterjee A, Chatterjee U, Ghosh MK. Activation of protein kinase CK2 attenuates FOXO3a functioning in a PML-dependent manner: implications in human prostate cancer. Cell Death Dis. 2013; 4:e543.
    • (2013) Cell Death Dis. , vol.4
    • Chatterjee, A.1    Chatterjee, U.2    Ghosh, M.K.3
  • 49
    • 84906962169 scopus 로고    scopus 로고
    • Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies
    • Mimeault M, Batra SK. Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies. Mol Aspects Med. 2014; 39:3-32.
    • (2014) Mol Aspects Med. , vol.39 , pp. 3-32
    • Mimeault, M.1    Batra, S.K.2
  • 50
    • 84927126692 scopus 로고    scopus 로고
    • DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2
    • Qin J, Ji J, Deng R, Tang J, Yang F, Feng GK, Chen WD, Wu XQ, Qian XJ, Ding K, Zhu XF. DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2. Oncotarget. 2015; 6:6944-6958.
    • (2015) Oncotarget. , vol.6 , pp. 6944-6958
    • Qin, J.1    Ji, J.2    Deng, R.3    Tang, J.4    Yang, F.5    Feng, G.K.6    Chen, W.D.7    Wu, X.Q.8    Qian, X.J.9    Ding, K.10    Zhu, X.F.11
  • 53
    • 0032078889 scopus 로고    scopus 로고
    • Chromosomal abnormalities of a new nasopharyngeal carcinoma cell line (NPC-BM1) derived from a bone marrow metastatic lesion
    • Liao SK, Perng YP, Shen YC, Chung PJ, Chang YS, Wang CH. Chromosomal abnormalities of a new nasopharyngeal carcinoma cell line (NPC-BM1) derived from a bone marrow metastatic lesion. Cancer Genet Cytogenet. 1998; 103:52-58.
    • (1998) Cancer Genet Cytogenet. , vol.103 , pp. 52-58
    • Liao, S.K.1    Perng, Y.P.2    Shen, Y.C.3    Chung, P.J.4    Chang, Y.S.5    Wang, C.H.6


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