P53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells

Biochemical and Biophysical Research Communications

Volumn 467, Issue 2, 2015, Pages 348-353

  Cappadone, C ^a   Stefanelli, C ^a   Malucelli, E ^a   Zini, M ^b   Onofrillo, C ^a   Locatelli, A ^a   Rambaldi, M ^a   Sargenti, A ^a   Merolle, L ^c   Farruggia, G ^a,d   Graziadio, A ^a   Montanaro, L ^a   Iotti, S ^a,d  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c SINCROTRONE TRIESTE   (Italy)

^d NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

Author keywords

Apoptosis; Indole derivative; Osteosarcoma; p53; SaOS2; U2OS

Indexed keywords

ALKALINE PHOSPHATASE; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; NSC 743420; PROTEIN P53; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE INHIBITOR 1A; NSC743420; SMALL INTERFERING RNA; THIAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL; PRIORITY JOURNAL; SAOS 2 CELL LINE; U2OS CELL LINE; WILD TYPE; ANTAGONISTS AND INHIBITORS; CELL CYCLE CHECKPOINT; DRUG EFFECTS; GENE EXPRESSION; GENETICS; METABOLISM; OSTEOBLAST; PATHOLOGY; TUMOR CELL LINE;

ALKALINE PHOSPHATASE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE EXPRESSION; HUMANS; INDOLES; OSTEOBLASTS; RNA, SMALL INTERFERING; THIAZOLES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84944394512     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.09.154     Document Type: Article

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