Effects of Acute Lithium Treatment on Brain Levels of Inflammatory Mediators in Poststroke Rats

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Boyko, Matthew ^a   Nassar, Ahmad ^b   Kaplanski, Jacob ^b   Zlotnik, Alexander ^a   Sharon Granit, Yael ^b   Azab, Abed N ^b  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; LITHIUM CHLORIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE; LITHIUM; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BRAIN HOMOGENATE; BRAIN ISCHEMIA; BRAIN LEVEL; BRAIN REGION; CONTROLLED STUDY; DRUG EFFECT; FEVER; MALE; MEDIATOR; MIDDLE CEREBRAL ARTERY OCCLUSION; MORTALITY; NONHUMAN; RAT; SINGLE DRUG DOSE; ANIMAL; BRAIN; DISEASE MODEL; METABOLISM; PATHOLOGY; STROKE; WISTAR RAT;

ANIMALS; BRAIN; CYTOKINES; DISEASE MODELS, ANIMAL; INFLAMMATION MEDIATORS; LITHIUM; MALE; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; STROKE;

EID: 84944348482     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/916234     Document Type: Article

References (39)

1. World Health Organization, The Global Burden of Disease: 2004 Update,WorldHealth Organization, Geneva, Switzerland, 2008
2. D. Lloyd-Jones, R. J. Adams, T. M. Brown et al., "Heart disease and stroke statistics-2010 update: a report from the American Heart Association," Circulation, vol. 121, no. 7, pp. e46-e215, 2010
3. W. D. Rosamond, A. R. Folsom, L. E. Chambless et al., "Stroke incidence and survival among middle-aged adults: 9-year follow-up of the Atherosclerosis Risk in Communities (ARIC) cohort," Stroke, vol. 30, no. 4, pp. 736-743, 1999
4. C. Iadecola and J. Anrather, "The immunology of stroke: from mechanisms to translation," Nature Medicine, vol. 17, no. 7, pp. 796-808, 2011
5. E. Tarkowski, L. Rosengren, C. Blomstrand et al., "Intrathecal release of pro-and anti-inflammatory cytokines during stroke," Clinical & Experimental Immunology, vol. 110, no. 3, pp. 492-499, 1997
6. N. Vila, J. Castillo, A. Dávalos, and A. Chamorro, "Proinflammatory cytokines and early neurological worsening in ischemic stroke," Stroke, vol. 31, no. 10, pp. 2325-2329, 2000
7. D. Frenkel, Z. Huang, R. Maron et al., "Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells," The Journal of Immunology, vol. 171, no. 12, pp. 6549-6555, 2003
8. J. Castillo, A. Dávalos, J. Marrugat, and M. Noya, "Timing for fever-related brain damage in acute ischemic stroke," Stroke, vol. 29, no. 12, pp. 2455-2460, 1998
9. D. M. Greer, S. E. Funk,N. L. Reaven, M. Ouzounelli, and G. C. Uman, "Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis," Stroke, vol. 39, no. 11, pp. 3029-3035, 2008
10. K. Kikuchi, E. Tanaka, Y. Murai, and S. Tancharoen, "Clinical trials in acute ischemic stroke," CNS Drugs, vol. 28, no. 10, pp. 929-938, 2014
11. R. H. Belmaker, "Bipolar disorder,"The New England Journal of Medicine, vol. 351, no. 5, pp. 476-486, 2004
12. S. Nonaka, C. J. Hough, and D.-M. Chuang, "Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx," Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 5, pp. 2642-2647, 1998
13. J. Xu, J. Culman, A. Blume, S. Brecht, and P. Gohlke, "Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death," Stroke, vol. 34,no. 5, pp. 1287-1292, 2003
14. A. Nassar and A. N. Azab, "Effects of lithium on inflammation," ACS Chemical Neuroscience, vol. 5, no. 6, pp. 451-458, 2014
15. E. Z. Longa, P. R. Weinstein, S. Carlson, and R. Cummins, "Reversible middle cerebral artery occlusion without craniectomy in rats," Stroke, vol. 20, no. 1, pp. 84-91, 1989
16. M. Boyko, A. Zlotnik, B. F. Gruenbaum et al., "Pyruvate's blood glutamate scavenging activity contributes to the spectrum of its neuroprotectivemechanisms in a ratmodel of stroke," European Journal of Neuroscience, vol. 34, no. 9, pp. 1432-1441, 2011
17. M. A. Nunes, T. A. Viel, and H. S. Buck, "Microdose lithium treatment stabilized cognitive impairment in patients with Alzheimer's disease," Current Alzheimer Research, vol. 10, no. 1, pp. 104-107, 2013
18. F. Fornai, P. Longone, L. Cafaro et al., "Lithium delays progression ofamyotrophic lateral sclerosis," Proceedings of theNational Academy of Sciences of the United States of America, vol. 105, no. 6, pp. 2052-2057, 2008
19. E. J. Goetzl, S. An, and W. L. Smith, "Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases,"TheFASEB Journal, vol. 9, no. 11,pp. 1051-1058, 1995
20. J. Kaplanski, A. Nassar, Y. Sharon-Granit, A. Jabareen, S. L. Kobal, and A. N. Azab, "Lithium attenuates lipopolysaccharideinduced hypothermia in rats," European Review forMedical and Pharmacological Sciences, vol. 18, no. 12, pp. 1829-1837, 2014
21. F. Bosetti, J. Rintala, R. Seemann et al., "Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E2 concentration in rat brain," Molecular Psychiatry, vol. 7, no. 8, pp. 845-850, 2002
22. F. Li, T. Omae, and M. Fisher, "Spontaneous hyperthermia and itsmechanism in the intraluminal suture middle cerebral artery occlusion model of rats," Stroke, vol. 30, no. 11, pp. 2464-2471, 1999
23. J. J. Legos, A. A. Mangoni, S. J. Read et al., "Programmable microchip monitoring of post-stroke pyrexia: effects of aspirin and paracetamol on temperature and infarct size in the rat," Journal of Neuroscience Methods, vol. 113, no. 2, pp. 159-166, 2002
24. K. Walentynowicz, M. Szefer, B. Wojtal, P. Terlecki, S. Wrotek, and W. Kozak, "Role of prostaglandins in heme-induced fever," Journal of Physiology and Pharmacology, vol. 57,no. 8, pp. 73-82, 2006
25. P. Rider, Y. Carmi, E. Voronov, and R. N. Apte, "Interleukin-1," Seminars in Immunology, vol. 25, no. 6, pp. 430-438, 2013
26. N. M. Luheshi, K. J. Kovács, G. Lopez-Castejon, D. Brough, and A. Denes, "Interleukin-1 expression precedes IL-1 after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues," Journal of Neuroinflammation, vol. 8, article 186, 2011
27. J. Scheller, A. Chalaris, D. Schmidt-Arras, and S. Rose-John, "The pro-and anti-inflammatory properties of the cytokine interleukin-6," Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1813, no. 5, pp. 878-888, 2011
28. T. H. S. Ng, G. J. Britton, E. V. Hill, J. Verhagen, B. R. Burton, and D. C. Wraith, "Regulation of adaptive immunity; the role of interleukin-10," Frontiers in Immunology, vol. 4, article 129, 2013
29. N. Vila, J. Castillo, A. Dávalos, A. Esteve, A. M. Planas, and A . Chamorro, "Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke," Stroke, vol. 34, no. 3, pp. 671-675, 2003
30. D. A. A. Vignali and V. K. Kuchroo, "IL-12 family cytokines: immunological playmakers," Nature Immunology, vol. 13, no. 8, pp. 722-728, 2012
31. F. Konoeda, T. Shichita, H. Yoshida et al., "Therapeutic effect of IL-12/23 and their signaling pathway blockade on brain ischemia model," Biochemical and Biophysical Research Communications, vol. 402, no. 3, pp. 500-506, 2010
32. K. Narasimhalu, J. Lee,Y. L. Leong et al., "Inflammatorymarkers and their association with post stroke cognitive decline," International Journal of Stroke, vol. 10, no. 4, pp. 513-518, 2015
33. H. Zelová and J. Hosek, "TNF- signalling and inflammation: interactions between old acquaintances," Inflammation Research, vol. 62, no. 7, pp. 641-651, 2013
34. A. Modabbernia, S. Taslimi, E. Brietzke, and M. Ashrafi, "Cytokine alterations in bipolar disorder: a meta-analysis of 30 studies," Biological Psychiatry, vol. 74, no. 1, pp. 15-25, 2013
35. J. R. Caso, J. M. Pradillo, O. Hurtado, P. Lorenzo, M. A. Moro, and I. Lizasoain, "Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke," Circulation, vol. 115, no. 12, pp. 1599-1608, 2007
36. R. Zhou, Z. Yang, X. Tang, Y. Tan, X. Wu, and F. Liu, "Propofol protects against focal cerebral ischemia via inhibition of microglia-mediated proinflammatory cytokines in a rat model of experimental stroke," PLoS ONE, vol. 8, no. 12, Article ID e82729, 2013
37. S. Nonaka and D. M. Chuang, "Neuroprotective effects of chronic lithiumon focal cerebral ischemia in rats," NeuroReport, vol. 9, no. 9, pp. 2081-2084, 1998
38. R. Sheng, L.-S. Zhang, R. Han, B. Gao, X.-Q. Liu, and Z.-H. Qin, "Combined prostaglandin E1 and lithium exert potent neuroprotection in a rat model of cerebral ischemia," Acta Pharmacologica Sinica, vol. 32, no. 3, pp. 303-310, 2011
39. S. E. Mohammadianinejad, N. Majdinasab, S. A. Sajedi, F. Abdollahi, M. M. Moqaddam, and F. Sadr, "The effect of lithiumin post-stroke motor recovery: a double-blind, placebocontrolled, randomized clinical trial," Clinical Neuropharmacology, vol. 37, no. 3, pp. 73-78, 2014.