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Volumn 36, Issue 10, 2015, Pages 8093-8100

Inhibition of LDHA suppresses tumor progression in prostate cancer

Author keywords

LDHA; Progression; Prostate cancer; Warburg effect

Indexed keywords

3 DIHYDROXY 6 METHYL 7 (PHENYLMETHYL) 4 PROPYLNAPHTHALENE 1 CARBOXYLIC ACID; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CATHEPSIN B; GELATINASE B; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A; LACTIC ACID; MESSENGER RNA; PROTEINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UROKINASE; ISOENZYME; LACTATE DEHYDROGENASE 5;

EID: 84944280952     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3540-x     Document Type: Article
Times cited : (117)

References (17)
  • 2
    • 27944474670 scopus 로고    scopus 로고
    • Growth inhibitory effect of doxazosin on prostate and bladder cancer cells. Is the serotonin receptor pathway involved?
    • COI: 1:CAS:528:DC%2BD2MXht12it7bL, PID: 16309229
    • Siddiqui EJ, Shabbir M, Thompson CS, Mumtaz FH, Mikhailidis DP. Growth inhibitory effect of doxazosin on prostate and bladder cancer cells. Is the serotonin receptor pathway involved? Anticancer Res. 2005;25:4281–6.
    • (2005) Anticancer Res , vol.25 , pp. 4281-4286
    • Siddiqui, E.J.1    Shabbir, M.2    Thompson, C.S.3    Mumtaz, F.H.4    Mikhailidis, D.P.5
  • 3
    • 29844443964 scopus 로고    scopus 로고
    • Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies
    • COI: 1:CAS:528:DC%2BD2MXhtlCmsbbP, PID: 16195239
    • Mimeault M, Batra SK. Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies. Carcinogenesis. 2006;27:1–22.
    • (2006) Carcinogenesis , vol.27 , pp. 1-22
    • Mimeault, M.1    Batra, S.K.2
  • 4
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • COI: 1:CAS:528:DC%2BD2cXptFegt7w%3D, PID: 15516961
    • Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004;4:891–9.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 5
    • 84905979612 scopus 로고    scopus 로고
    • A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer
    • COI: 1:CAS:528:DC%2BC2cXhtlCltr3N
    • Shi M, Cui J, Du J, Wei D, Jia Z, Zhang J, et al. A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer. Clin Cancer Res: Off J Am Assoc Cancer Res. 2014;20:4370–80.
    • (2014) Clin Cancer Res: Off J Am Assoc Cancer Res , vol.20 , pp. 4370-4380
    • Shi, M.1    Cui, J.2    Du, J.3    Wei, D.4    Jia, Z.5    Zhang, J.6
  • 6
    • 84867097473 scopus 로고    scopus 로고
    • Knockdown of lactate dehydrogenase a suppresses tumor growth and metastasis of human hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC38XhsVehtLrL, PID: 22897481
    • Sheng SL, Liu JJ, Dai YH, Sun XG, Xiong XP, Huang G. Knockdown of lactate dehydrogenase a suppresses tumor growth and metastasis of human hepatocellular carcinoma. FEBS J. 2012;279:3898–910.
    • (2012) FEBS J , vol.279 , pp. 3898-3910
    • Sheng, S.L.1    Liu, J.J.2    Dai, Y.H.3    Sun, X.G.4    Xiong, X.P.5    Huang, G.6
  • 7
    • 70350564782 scopus 로고    scopus 로고
    • Upregulation of lactate dehydrogenase a by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth
    • COI: 1:CAS:528:DC%2BD1MXps1ahurc%3D, PID: 19668225
    • Zhao YH, Zhou M, Liu H, Ding Y, Khong HT, Yu D, et al. Upregulation of lactate dehydrogenase a by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth. Oncogene. 2009;28:3689–701.
    • (2009) Oncogene , vol.28 , pp. 3689-3701
    • Zhao, Y.H.1    Zhou, M.2    Liu, H.3    Ding, Y.4    Khong, H.T.5    Yu, D.6
  • 8
    • 33744783432 scopus 로고    scopus 로고
    • Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
    • COI: 1:CAS:528:DC%2BD28Xmt1eksLk%3D, PID: 16766262
    • Fantin VR, St-Pierre J, Leder P. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell. 2006;9:425–34.
    • (2006) Cancer Cell , vol.9 , pp. 425-434
    • Fantin, V.R.1    St-Pierre, J.2    Leder, P.3
  • 9
    • 76649126249 scopus 로고    scopus 로고
    • Inhibition of lactate dehydrogenase a induces oxidative stress and inhibits tumor progression
    • COI: 1:CAS:528:DC%2BC3cXhvFCit7g%3D, PID: 20133848
    • Le A, Cooper CR, Gouw AM, Dinavahi R, Maitra A, Deck LM, et al. Inhibition of lactate dehydrogenase a induces oxidative stress and inhibits tumor progression. Proc Natl Acad Sci U S A. 2010;107:2037–42.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2037-2042
    • Le, A.1    Cooper, C.R.2    Gouw, A.M.3    Dinavahi, R.4    Maitra, A.5    Deck, L.M.6
  • 10
    • 84856213516 scopus 로고    scopus 로고
    • LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis
    • COI: 1:CAS:528:DC%2BC38XhtFKms7Y%3D, PID: 21452021
    • Wang ZY, Loo TY, Shen JG, Wang N, Wang DM, Yang DP, et al. LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis. Breast Cancer Res Treat. 2012;131:791–800.
    • (2012) Breast Cancer Res Treat , vol.131 , pp. 791-800
    • Wang, Z.Y.1    Loo, T.Y.2    Shen, J.G.3    Wang, N.4    Wang, D.M.5    Yang, D.P.6
  • 11
    • 84899914457 scopus 로고    scopus 로고
    • Lactate dehydrogenase 5 isoenzyme overexpression defines resistance of prostate cancer to radiotherapy
    • COI: 1:CAS:528:DC%2BC2cXmtFSqsLw%3D, PID: 24714743
    • Koukourakis MI, Giatromanolaki A, Panteliadou M, Pouliliou SE, Chondrou PS, Mavropoulou S, et al. Lactate dehydrogenase 5 isoenzyme overexpression defines resistance of prostate cancer to radiotherapy. Br J Cancer. 2014;110:2217–23.
    • (2014) Br J Cancer , vol.110 , pp. 2217-2223
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Panteliadou, M.3    Pouliliou, S.E.4    Chondrou, P.S.5    Mavropoulou, S.6
  • 12
    • 84863661689 scopus 로고    scopus 로고
    • Therapeutic targets in cancer cell metabolism and autophagy
    • COI: 1:CAS:528:DC%2BC38XpvFGgsr4%3D, PID: 22781696
    • Cheong H, Lu C, Lindsten T, Thompson CB. Therapeutic targets in cancer cell metabolism and autophagy. Nat Biotechnol. 2012;30:671–8.
    • (2012) Nat Biotechnol , vol.30 , pp. 671-678
    • Cheong, H.1    Lu, C.2    Lindsten, T.3    Thompson, C.B.4
  • 13
    • 84878678600 scopus 로고    scopus 로고
    • Lactate dehydrogenase a is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells
    • COI: 1:CAS:528:DC%2BC3sXos1yktro%3D, PID: 23404405
    • Rong Y, Wu W, Ni X, Kuang T, Jin D, Wang D, et al. Lactate dehydrogenase a is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells. Tumour Biol. 2013;34:1523–30.
    • (2013) Tumour Biol , vol.34 , pp. 1523-1530
    • Rong, Y.1    Wu, W.2    Ni, X.3    Kuang, T.4    Jin, D.5    Wang, D.6
  • 14
    • 84872790592 scopus 로고    scopus 로고
    • LDHA is necessary for the tumorigenicity of esophageal squamous cell carcinoma
    • COI: 1:CAS:528:DC%2BC3sXhsVeru7w%3D, PID: 22961700
    • Yao F, Zhao T, Zhong C, Zhu J, Zhao H. LDHA is necessary for the tumorigenicity of esophageal squamous cell carcinoma. Tumour Biol. 2013;34:25–31.
    • (2013) Tumour Biol , vol.34 , pp. 25-31
    • Yao, F.1    Zhao, T.2    Zhong, C.3    Zhu, J.4    Zhao, H.5
  • 15
    • 80054046029 scopus 로고    scopus 로고
    • Aerobic glycolysis: meeting the metabolic requirements of cell proliferation
    • COI: 1:CAS:528:DC%2BC3MXhsFyqtbfN, PID: 21985671
    • Lunt SY, Vander Heiden MG. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. Annu Rev Cell Dev Biol. 2011;27:441–64.
    • (2011) Annu Rev Cell Dev Biol , vol.27 , pp. 441-464
    • Lunt, S.Y.1    Vander Heiden, M.G.2
  • 16
    • 84869009687 scopus 로고    scopus 로고
    • How cancer metabolism is tuned for proliferation and vulnerable to disruption
    • COI: 1:CAS:528:DC%2BC38Xhs1Ogt77F, PID: 23151579
    • Schulze A, Harris AL. How cancer metabolism is tuned for proliferation and vulnerable to disruption. Nature. 2012;491:364–73.
    • (2012) Nature , vol.491 , pp. 364-373
    • Schulze, A.1    Harris, A.L.2
  • 17
    • 84891846840 scopus 로고    scopus 로고
    • How does cancer cell metabolism affect tumor migration and invasion?
    • Han T, Kang D, Ji D, Wang X, Zhan W, Fu M, et al. How does cancer cell metabolism affect tumor migration and invasion? Cell Adhes Migr. 2013;7:395–403.
    • (2013) Cell Adhes Migr , vol.7 , pp. 395-403
    • Han, T.1    Kang, D.2    Ji, D.3    Wang, X.4    Zhan, W.5    Fu, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.