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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 21, 2015, Pages 4793-4796

Aryl amide small-molecule inhibitors of microRNA miR-21 function

(5) Naro, Yuta a Thomas, Meryl a Stephens, Matthew D b Connelly, Colleen M b Deiters, Alexander a

a UNIVERSITY OF PITTSBURGH (United States)

b NORTH CAROLINA STATE UNIVERSITY (United States)

Author keywords

Cancer; Gene regulation; MicroRNA; miR 21; Post transcriptional regulation; Small molecule inhibitors

Indexed keywords

AMIDE; ANTINEOPLASTIC AGENT; ARYL AMIDE SMALL MOLECULE INHIBITOR; MICRORNA 21; UNCLASSIFIED DRUG; MICRORNA; MIRN21 MICRORNA, HUMAN; MOLECULAR LIBRARY;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG DEVELOPMENT; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; EC50; FEMALE; HELA CELL LINE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; GENETICS; MOLECULAR LIBRARY; PHARMACOLOGY; SYNTHESIS; TUMOR CELL LINE;

AMIDES; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; MICRORNAS; MOLECULAR STRUCTURE; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84944274437 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2015.07.016 Document Type: Article

Times cited : (48)

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