메뉴 건너뛰기




Volumn 129, Issue 1, 2016, Pages 115.e9-115.e16

Low Cobalamin Levels as Predictors of Cobalamin Deficiency: Importance of Comorbidities Associated with Increased Oxidative Stress

Author keywords

Cobalamin; Homocysteine; Methylmalonic acid; Oxidative stress; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; HOMOCYSTEINE; METHYLMALONIC ACID; OXIDIZING AGENT; BIOLOGICAL MARKER;

EID: 84944111802     PISSN: 00029343     EISSN: 15557162     Source Type: Journal    
DOI: 10.1016/j.amjmed.2015.07.017     Document Type: Article
Times cited : (15)

References (34)
  • 1
    • 84877978315 scopus 로고    scopus 로고
    • Vitamin B12 deficiency
    • 1 Stabler, S.P., Vitamin B12 deficiency. N Engl J Med 368 (2013), 149–160.
    • (2013) N Engl J Med , vol.368 , pp. 149-160
    • Stabler, S.P.1
  • 2
    • 84934272419 scopus 로고    scopus 로고
    • A review of the cut-off points for the diagnosis of vitamin B12 deficiency in the general population
    • 2 Aparicio-Ugarriza, R., Palacios, G., Gonzalez-Cross, M., A review of the cut-off points for the diagnosis of vitamin B12 deficiency in the general population. Clin Chem Lab Med 53:8 (2015), 1149–1159.
    • (2015) Clin Chem Lab Med , vol.53 , Issue.8 , pp. 1149-1159
    • Aparicio-Ugarriza, R.1    Palacios, G.2    Gonzalez-Cross, M.3
  • 3
    • 79960865571 scopus 로고    scopus 로고
    • Monitoring of vitamin B12 nutritional status in the United States by using plasma MMA and serum vitamin B12
    • 3 Bailey, R.L., Carmel, R., Green, R., et al. Monitoring of vitamin B12 nutritional status in the United States by using plasma MMA and serum vitamin B12. Am J Clin Nutr 94 (2011), 552–561.
    • (2011) Am J Clin Nutr , vol.94 , pp. 552-561
    • Bailey, R.L.1    Carmel, R.2    Green, R.3
  • 4
    • 34047178356 scopus 로고    scopus 로고
    • Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment
    • 4 Solomon, L.R., Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment. Blood Rev 21 (2007), 113–130.
    • (2007) Blood Rev , vol.21 , pp. 113-130
    • Solomon, L.R.1
  • 5
    • 0037775351 scopus 로고    scopus 로고
    • Cobalamin deficiency in general practice. Assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current diagnostic strategies
    • 5 Holleland, G., Schneede, J., Ueland, P.M., Lund, P.K., Refsum, H., Sandberg, S., Cobalamin deficiency in general practice. Assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current diagnostic strategies. Clin Chem 45 (1999), 189–198.
    • (1999) Clin Chem , vol.45 , pp. 189-198
    • Holleland, G.1    Schneede, J.2    Ueland, P.M.3    Lund, P.K.4    Refsum, H.5    Sandberg, S.6
  • 6
    • 84910621174 scopus 로고    scopus 로고
    • Micronutrient status in female university students: iron, zinc, copper, selenium, vitamin B12 and folate
    • 6 Fayet-Moore, F., Petocz, P., Samman, S., Micronutrient status in female university students: iron, zinc, copper, selenium, vitamin B12 and folate. Nutrients 6 (2014), 5103–5116.
    • (2014) Nutrients , vol.6 , pp. 5103-5116
    • Fayet-Moore, F.1    Petocz, P.2    Samman, S.3
  • 7
    • 84930474428 scopus 로고    scopus 로고
    • Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress
    • 7 Solomon, L.R., Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress. Eur J Clin Nutr 69 (2015), 687–692.
    • (2015) Eur J Clin Nutr , vol.69 , pp. 687-692
    • Solomon, L.R.1
  • 8
    • 71749120426 scopus 로고    scopus 로고
    • Determinants of plasma methylmalonic acid in a large population. Implications for the assessment of vitamin B12 status
    • 8 Vogiatzoglu, A., Oulhaj, A., Smith, D.A., et al. Determinants of plasma methylmalonic acid in a large population. Implications for the assessment of vitamin B12 status. Clin Chem 55 (2009), 2198–2206.
    • (2009) Clin Chem , vol.55 , pp. 2198-2206
    • Vogiatzoglu, A.1    Oulhaj, A.2    Smith, D.A.3
  • 9
    • 84855958103 scopus 로고    scopus 로고
    • Do we need to reconsider the desirable blood level of vitamin B12?
    • 9 Smith, A.D., Refsum, H., Do we need to reconsider the desirable blood level of vitamin B12?. J Intern Med 271 (2011), 179–182.
    • (2011) J Intern Med , vol.271 , pp. 179-182
    • Smith, A.D.1    Refsum, H.2
  • 10
    • 0025335524 scopus 로고
    • Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid and total homocysteine concentrations
    • 10 Lindenbaum, J., Savage, D.G., Stabler, S.P., Allen, R.N., Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid and total homocysteine concentrations. Am J Hematol 34 (1990), 99–107.
    • (1990) Am J Hematol , vol.34 , pp. 99-107
    • Lindenbaum, J.1    Savage, D.G.2    Stabler, S.P.3    Allen, R.N.4
  • 11
    • 0022651030 scopus 로고
    • Cobalamin and unsaturated transcobalamin values in pernicious anaemia: relation to treatment
    • 11 Magnus, E.M., Cobalamin and unsaturated transcobalamin values in pernicious anaemia: relation to treatment. Scand J Haematol 36 (1986), 457–465.
    • (1986) Scand J Haematol , vol.36 , pp. 457-465
    • Magnus, E.M.1
  • 12
    • 48249084968 scopus 로고    scopus 로고
    • The use of blood concentrations of vitamins and theirs respective functional indicators to define folate and vitamin B12 status
    • 12 Selhub, J., Jacques, P.F., Dallal, G., Choumenkovitch, S., Rogers, G., The use of blood concentrations of vitamins and theirs respective functional indicators to define folate and vitamin B12 status. Food Nutr Bull 29:suppl (2008), 567–573.
    • (2008) Food Nutr Bull , vol.29 , pp. 567-573
    • Selhub, J.1    Jacques, P.F.2    Dallal, G.3    Choumenkovitch, S.4    Rogers, G.5
  • 13
    • 12844254924 scopus 로고    scopus 로고
    • Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid and homocysteine testing
    • 13 Solomon, L.R., Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid and homocysteine testing. Blood 105 (2005), 978–985.
    • (2005) Blood , vol.105 , pp. 978-985
    • Solomon, L.R.1
  • 14
    • 79956095850 scopus 로고    scopus 로고
    • Diabetes mellitus as a cause of clinically significant functional cobalamin deficiency
    • 14 Solomon, L.R., Diabetes mellitus as a cause of clinically significant functional cobalamin deficiency. Diabetes Care 34 (2011), 1077–1080.
    • (2011) Diabetes Care , vol.34 , pp. 1077-1080
    • Solomon, L.R.1
  • 16
    • 24044507638 scopus 로고    scopus 로고
    • Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2003
    • 16 Pfeiffer, C.M., Caudill, S.P., Gunter, E.W., Osterloh, J., Sampson, E.J., Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2003. Am J Clin Nutr 82 (2005), 442–450.
    • (2005) Am J Clin Nutr , vol.82 , pp. 442-450
    • Pfeiffer, C.M.1    Caudill, S.P.2    Gunter, E.W.3    Osterloh, J.4    Sampson, E.J.5
  • 17
    • 84890558502 scopus 로고    scopus 로고
    • An audit of holotranscobalamin (“Active” B12) and methylmalonic acid assays for the assessment of vitamin B12 status: application in a mixed patient population
    • 17 Sobczynska-Malefora, A., Gorska, R., Pelisser, M., Ruwona, P., Witchlow, B., Harrington, D.J., An audit of holotranscobalamin (“Active” B12) and methylmalonic acid assays for the assessment of vitamin B12 status: application in a mixed patient population. Clin Biochem 47 (2014), 82–86.
    • (2014) Clin Biochem , vol.47 , pp. 82-86
    • Sobczynska-Malefora, A.1    Gorska, R.2    Pelisser, M.3    Ruwona, P.4    Witchlow, B.5    Harrington, D.J.6
  • 18
    • 84896320373 scopus 로고    scopus 로고
    • Role of serum holotranscobalamin (holoTC) in the diagnosis of patients with low serum cobalamin. Comparison with methylmalonic acid and homocysteine
    • 18 Remacha, A.F., Sarda, M.P., Canals, C., et al. Role of serum holotranscobalamin (holoTC) in the diagnosis of patients with low serum cobalamin. Comparison with methylmalonic acid and homocysteine. Ann Hematol 93 (2014), 565–569.
    • (2014) Ann Hematol , vol.93 , pp. 565-569
    • Remacha, A.F.1    Sarda, M.P.2    Canals, C.3
  • 19
    • 33144490305 scopus 로고    scopus 로고
    • Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling
    • 19 Hansen, J.M., Go, Y.-M., Jones, D.P., Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling. Annu Rev Pharmacol Toxicol 46 (2006), 215–234.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 215-234
    • Hansen, J.M.1    Go, Y.-M.2    Jones, D.P.3
  • 20
    • 0034924762 scopus 로고    scopus 로고
    • Increased plasma methylmalonic acid level does not predict clinical manifestations of vitamin B12 deficiency
    • 20 Hvas, A.-M., Ellegard, J., Nexo, E., Increased plasma methylmalonic acid level does not predict clinical manifestations of vitamin B12 deficiency. Arch Intern Med 161 (2001), 1534–1541.
    • (2001) Arch Intern Med , vol.161 , pp. 1534-1541
    • Hvas, A.-M.1    Ellegard, J.2    Nexo, E.3
  • 21
    • 0022635401 scopus 로고
    • Is nitrous oxide a dangerous anesthetic for vitamin B12-deficient subjects?
    • 21 Schilling, R.F., Is nitrous oxide a dangerous anesthetic for vitamin B12-deficient subjects?. JAMA 255 (1986), 1605–1606.
    • (1986) JAMA , vol.255 , pp. 1605-1606
    • Schilling, R.F.1
  • 22
    • 0027494272 scopus 로고
    • Neurologic degeneration associated with nitrous oxide anesthesia in patients with vitamin B12 deficiency
    • 22 Flippo, T.S., Holder, W.D., Neurologic degeneration associated with nitrous oxide anesthesia in patients with vitamin B12 deficiency. Arch Surg 128 (1993), 1391–1395.
    • (1993) Arch Surg , vol.128 , pp. 1391-1395
    • Flippo, T.S.1    Holder, W.D.2
  • 23
    • 0029059626 scopus 로고
    • ‘Anesthesia paresthetica’: nitrous oxide induced cobalamin deficiency
    • 23 Kinsella, L.J., Green, R., ‘Anesthesia paresthetica’: nitrous oxide induced cobalamin deficiency. Neurology 45 (1995), 1608–1610.
    • (1995) Neurology , vol.45 , pp. 1608-1610
    • Kinsella, L.J.1    Green, R.2
  • 24
    • 0029930038 scopus 로고    scopus 로고
    • Severe combined degeneration of the spinal cord after nitrous oxide anaesthesia in a vegetarian
    • 24 Rosener, M., Dichgans, J., Severe combined degeneration of the spinal cord after nitrous oxide anaesthesia in a vegetarian. J Neurol Neurosurg Psychiatry, 60(3), 1996, 354.
    • (1996) J Neurol Neurosurg Psychiatry , vol.60 , Issue.3 , pp. 354
    • Rosener, M.1    Dichgans, J.2
  • 25
    • 0032789770 scopus 로고    scopus 로고
    • Myeloneuropathy following nitrous oxide anaesthesia in a patient with macrocytic anaemia
    • 25 Sesso, R.M., Iunes, Y., Melo, A.C.P., Myeloneuropathy following nitrous oxide anaesthesia in a patient with macrocytic anaemia. Neuroradiology 41:8 (1999), 588–590.
    • (1999) Neuroradiology , vol.41 , Issue.8 , pp. 588-590
    • Sesso, R.M.1    Iunes, Y.2    Melo, A.C.P.3
  • 26
    • 0036388554 scopus 로고    scopus 로고
    • MR findings in subacute degeneration of the spinal cord caused by nitrous oxide anaesthesia – two cases
    • 26 Ilniczky, S., Jelencsik, I., Kenez, J., Szirmai, I., MR findings in subacute degeneration of the spinal cord caused by nitrous oxide anaesthesia – two cases. Eur J Neurol 9 (2002), 101–104.
    • (2002) Eur J Neurol , vol.9 , pp. 101-104
    • Ilniczky, S.1    Jelencsik, I.2    Kenez, J.3    Szirmai, I.4
  • 27
    • 60449113636 scopus 로고    scopus 로고
    • Subacute combined degeneration of the spinal cord caused by nitrous oxide anaesthesia
    • 27 Renard, D., Dutray, A., Remy, A., Castelnovo, G., Labauge, P., Subacute combined degeneration of the spinal cord caused by nitrous oxide anaesthesia. Neurol Sci 30 (2009), 75–76.
    • (2009) Neurol Sci , vol.30 , pp. 75-76
    • Renard, D.1    Dutray, A.2    Remy, A.3    Castelnovo, G.4    Labauge, P.5
  • 29
    • 85015033699 scopus 로고    scopus 로고
    • Vitamin B12-responsive neuropathies: a case series
    • [Epub ahead of print] Feb 24
    • 29 Solomon, L.R., Vitamin B12-responsive neuropathies: a case series. Nutr Neurosci, 2015 Feb 24 [Epub ahead of print].
    • (2015) Nutr Neurosci
    • Solomon, L.R.1
  • 30
    • 64349105596 scopus 로고    scopus 로고
    • Urinary methylmalonic acid in patients with acute myocardial infarction
    • 30 Celik, T., Kardesoglu, E., Iyisoy, A., Ozcan, O., Kilic, S., Yaman, H., Urinary methylmalonic acid in patients with acute myocardial infarction. Med Princ Pract 18:3 (2009), 217–222.
    • (2009) Med Princ Pract , vol.18 , Issue.3 , pp. 217-222
    • Celik, T.1    Kardesoglu, E.2    Iyisoy, A.3    Ozcan, O.4    Kilic, S.5    Yaman, H.6
  • 31
    • 33746326101 scopus 로고    scopus 로고
    • Oral pharmacologic doses of cobalamin may not be as effective as parenteral cobalamin therapy in reversing hyperhomocysteinemia and methylmalonic acidemia in apparently normal subjects
    • 31 Solomon, L.R., Oral pharmacologic doses of cobalamin may not be as effective as parenteral cobalamin therapy in reversing hyperhomocysteinemia and methylmalonic acidemia in apparently normal subjects. Clin Lab Haematol 28 (2006), 275–278.
    • (2006) Clin Lab Haematol , vol.28 , pp. 275-278
    • Solomon, L.R.1
  • 32
    • 84879501348 scopus 로고    scopus 로고
    • A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia
    • 32 Xu, G., Lv, Z.W., Feng, Y., Tang, W.Z., Xu, G.X., A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia. Pain Med 14 (2013), 884–894.
    • (2013) Pain Med , vol.14 , pp. 884-894
    • Xu, G.1    Lv, Z.W.2    Feng, Y.3    Tang, W.Z.4    Xu, G.X.5
  • 33
    • 0032772437 scopus 로고    scopus 로고
    • Intravenous methylcobalamin treatment of uremic and diabetic neuropathy in chronic hemodialysis patients
    • 33 Kuwabara, S., Nakazawa, R., Azuma, N., et al. Intravenous methylcobalamin treatment of uremic and diabetic neuropathy in chronic hemodialysis patients. Intern Med 38:6 (1999), 472–475.
    • (1999) Intern Med , vol.38 , Issue.6 , pp. 472-475
    • Kuwabara, S.1    Nakazawa, R.2    Azuma, N.3
  • 34
    • 41649110708 scopus 로고    scopus 로고
    • Altered red cell membrane compositions related to functional vitamin B12 deficiency manifested by elevated urine methylmalonic acid concentrations in patients with schizophrenia
    • 34 Ozcan, O., Ipcioglu, M., Gultepe, M., Basoglu, C., Altered red cell membrane compositions related to functional vitamin B12 deficiency manifested by elevated urine methylmalonic acid concentrations in patients with schizophrenia. Ann Clin Biochem 46 (2008), 44–49.
    • (2008) Ann Clin Biochem , vol.46 , pp. 44-49
    • Ozcan, O.1    Ipcioglu, M.2    Gultepe, M.3    Basoglu, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.