Cytokine modulation by IL-35 in mice with allergic rhinitis

American Journal of Rhinology and Allergy

Volumn 29, Issue 4, 2015, Pages 251-256

  Yokota, Makoto ^a   Suzuki, Motohiko ^a   Nakamura, Yoshihisa ^a   Ozaki, Shinya ^a   Murakami, Shingo ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 23; INTERLEUKIN 27; INTERLEUKIN 35; INTERLEUKIN 4; INTERLEUKIN 5; OVALBUMIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-35, MOUSE;

ALLERGIC RHINITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; MALE; MOUSE; NONHUMAN; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; DISEASE MODEL; GENETICS; METABOLISM; NOSE MUCOSA;

ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; IMMUNOSUPPRESSION; INTERLEUKINS; MICE; NASAL MUCOSA; RHINITIS, ALLERGIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84944066780     PISSN: 19458924     EISSN: 19458932     Source Type: Journal    
DOI: 10.2500/ajra.2015.29.4188     Document Type: Article

References (22)

1. Collison LW, Workman CJ, Kuo TT, et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450:566-569, 2007.
2. Collison LW, Chaturvedi V, Henderson AL, et al. IL-35-mediated induction of a potent regulatory T cell population. Nat Immunol 11:1093-1101, 2010.
3. Huang CH, Loo EX, Kuo IC, et al. Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35. J Immunol 187: 462-471, 2011.
4. Whitehead GS, Wilson RH, Nakano K, et al. IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease. J Allergy Clin Immunol 129:207-215.e201-205, 2012.
5. Suzuki M, Zheng X, Zhang X, et al. A novel allergen-specific therapy for allergy using CD40-silenced dendritic cells. J Allergy Clin Immunol 2010;125:737-743, 743.e731-743.e736.
6. Wills-Karp M, Luyimbazi J, Xu X, et al. Interleukin-13: Central mediator of allergic asthma. Science 282:2258-2261, 1998.
7. Peng J, Yang XO, Chang SH, et al. IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation. Cell Res 20:62-71, 2010.
8. Li Y, Sun M, Cheng H, et al. Silencing IL-23 expression by a small hairpin RNA protects against asthma in mice. Exp Mol Med 43:197-204, 2011.
9. Yoshida H, Nakaya M, and Miyazaki Y. Interleukin 27: A double-edged sword for offense and defense. J Leukoc Biol 86:1295-1303, 2009.
10. Yoshimoto T, Yasuda K, Mizuguchi J, et al. IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: A novel therapeutic way for Th2-mediated allergic inflammation. J Immunol 179:4415-4423, 2007.
11. Fogli LK, Sundrud MS, Goel S, et al. T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia. J Immunol 191:3100-3111, 2013.
12. Makihara S, Okano M, Fujiwara T, et al. Local expression of interleukin-17a is correlated with nasal eosinophilia and clinical severity in allergic rhinitis. Allergy Rhinol (Providence) 5:22-27, 2014.
13. Baumann R, Rabaszowski M, Stenin I, et al. Comparison of the nasal release of IL-4, IL-10, IL-17, CCL13/MCP-4, and CCL26/eotaxin-3 in allergic rhinitis during season and after allergen challenge. Am J Rhinol Allergy 27:266-272, 2013.
14. Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6:1123-1132, 2005.
15. Hunter CA. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat Rev Immunol 5:521-531, 2005.
16. Aggarwal S, Ghilardi N, Xie MH, et al. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 278:1910-1914, 2003.
17. McKenzie BS, Kastelein RA, and Cua DJ. Understanding the IL-23-IL-17 immune pathway. Trends Immunol 27:17-23, 2006.
18. Lukacs NW, Strieter RM, Chensue SW, et al. TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation. J Immunol 154:5411-5417, 1995.
19. Mo JH, Kang EK, Quan SH, et al. Anti-tumor necrosis factor-alpha treatment reduces allergic responses in an allergic rhinitis mouse model. Allergy 66:279-286, 2011.
20. Setoguchi R, Hori S, Takahashi T, and Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med 201:723-735, 2005.
21. Murai M, Turovskaya O, Kim G, et al. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat Immunol 10:1178-1184, 2009.
22. Fu CL, Ye YL, Lee YL, and Chiang BL. Effects of overexpression of IL-10, IL-12, TGF-beta and IL-4 on allergen induced change in bronchial responsiveness. Respir Res 7:72 2006.