메뉴 건너뛰기




Volumn 48, Issue 3, 2015, Pages 637-646

Increased Cerebrospinal Fluid Level of Insulin-like Growth Factor-II in Male Patients with Alzheimer's Disease

Author keywords

Alzheimer's disease; biomarker; cerebrospinal fluid; IGF II; IGFBP 1; IGFBP 2; mild cognitive impairment

Indexed keywords

BIOLOGICAL MARKER; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN C; TAU PROTEIN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); IGF2 PROTEIN, HUMAN; IGFBP-2 PROTEIN, HUMAN; IGFBP1 PROTEIN, HUMAN; MAPT PROTEIN, HUMAN; PEPTIDE FRAGMENT;

EID: 84943802298     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150351     Document Type: Article
Times cited : (34)

References (42)
  • 1
    • 28844432459 scopus 로고    scopus 로고
    • The insulin-like growth factor system and its pleiotropic functions in brain
    • Russo V, Gluckman P, Feldman E, Werther G (2005) The insulin-like growth factor system and its pleiotropic functions in brain. Endocr Rev 26, 916-943.
    • (2005) Endocr Rev , vol.26 , pp. 916-943
    • Russo, V.1    Gluckman, P.2    Feldman, E.3    Werther, G.4
  • 2
    • 84868195902 scopus 로고    scopus 로고
    • Neurodevelopmental effects of insulin-like growth factor signaling
    • O'Kusky J, Ye P (2012) Neurodevelopmental effects of insulin-like growth factor signaling. Front Neuroendocrinol 33, 230-251.
    • (2012) Front Neuroendocrinol , vol.33 , pp. 230-251
    • O'Kusky, J.1    Ye, P.2
  • 3
    • 0027170501 scopus 로고
    • Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type
    • Tham A, Nordberg A, Grissom F, Carlsson-Skwirut C, Viitanen M, Sara V (1993) Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type. J Neural Transm Park Dis Dement Sect 5, 165-176.
    • (1993) J Neural Transm Park Dis Dement Sect , vol.5 , pp. 165-176
    • Tham, A.1    Nordberg, A.2    Grissom, F.3    Carlsson-Skwirut, C.4    Viitanen, M.5    Sara, V.6
  • 4
    • 0032484055 scopus 로고    scopus 로고
    • Insulin-like growth factor system in serum and cerebrospinal fluid in patients with multiple sclerosis
    • Wilczak N, Schaaf M, Bredewold R, Streefland C, Teelken A, DeKeyser J (1998) Insulin-like growth factor system in serum and cerebrospinal fluid in patients with multiple sclerosis. Neurosci Lett 257, 168-170.
    • (1998) Neurosci Lett , vol.257 , pp. 168-170
    • Wilczak, N.1    Schaaf, M.2    Bredewold, R.3    Streefland, C.4    Teelken, A.5    DeKeyser, J.6
  • 5
    • 22044452112 scopus 로고    scopus 로고
    • Early developmental changes in IGF-I, IGF-II, IGF binding protein-1, and IGF binding protein-3 concentration in the cerebrospinal fluid of children
    • Bunn R, King W, Winkler M, Fowlkes J (2005) Early developmental changes in IGF-I, IGF-II, IGF binding protein-1, and IGF binding protein-3 concentration in the cerebrospinal fluid of children. Pediatr Res 58, 89-93.
    • (2005) Pediatr Res , vol.58 , pp. 89-93
    • Bunn, R.1    King, W.2    Winkler, M.3    Fowlkes, J.4
  • 6
    • 65949096494 scopus 로고    scopus 로고
    • Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease
    • Salehi Z, Mashayekhi F, Naji M (2008) Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease. Biofactors 33, 99-106.
    • (2008) Biofactors , vol.33 , pp. 99-106
    • Salehi, Z.1    Mashayekhi, F.2    Naji, M.3
  • 7
    • 77949912530 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-1 and insulin-like growth factor binding proteins in the serum and cerebrospinal fluid of patients with Parkinson's disease
    • Mashayekhi F, Mirzajani E, Naji M, Azari M (2010) Expression of insulin-like growth factor-1 and insulin-like growth factor binding proteins in the serum and cerebrospinal fluid of patients with Parkinson's disease. J Clin Neurosci 17, 623-627.
    • (2010) J Clin Neurosci , vol.17 , pp. 623-627
    • Mashayekhi, F.1    Mirzajani, E.2    Naji, M.3    Azari, M.4
  • 8
    • 84858631674 scopus 로고    scopus 로고
    • The many faces of insulin-like peptide signalling in the brain
    • Fernandez A, Torres-Alemán I (2012) The many faces of insulin-like peptide signalling in the brain. Nat Rev Neurosci 13, 225-239.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 225-239
    • Fernandez, A.1    Torres-Alemán, I.2
  • 9
    • 1442299204 scopus 로고    scopus 로고
    • The insulin-like growth factor-II/mannose-6 phosphate receptor: Structure, distribution and function in the central nervous system
    • Hawkes C, Kar S (2004) The insulin-like growth factor-II/mannose-6 phosphate receptor: Structure, distribution and function in the central nervous system. Brain Res Brain Res Rev 44, 117-140.
    • (2004) Brain Res Brain Res Rev , vol.44 , pp. 117-140
    • Hawkes, C.1    Kar, S.2
  • 10
    • 32544444711 scopus 로고    scopus 로고
    • Single transmembrane domain insulinlike growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-proteinsensitive, protein kinase C-dependent pathway
    • Hawkes C, Jhamandas J, Harris K, Fu W, MacDonald R, Kar S (2006) Single transmembrane domain insulinlike growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-proteinsensitive, protein kinase C-dependent pathway. J Neurosci 26, 585-596.
    • (2006) J Neurosci , vol.26 , pp. 585-596
    • Hawkes, C.1    Jhamandas, J.2    Harris, K.3    Fu, W.4    MacDonald, R.5    Kar, S.6
  • 11
    • 84862999971 scopus 로고    scopus 로고
    • Triangulated mal-signaling in Alzheimer's disease: Roles of neurotoxic ceramides, ER stress, and insulin resistance reviewed
    • de la Monte S (2012) Triangulated mal-signaling in Alzheimer's disease: Roles of neurotoxic ceramides, ER stress, and insulin resistance reviewed. J Alzheimers Dis 30(Suppl 2), S231-S249.
    • (2012) J Alzheimers Dis , vol.30 , pp. S231-S249
    • De La Monte, S.1
  • 12
    • 0036917631 scopus 로고    scopus 로고
    • Serum insulin-like growth factor i regulates brain amyloid-beta levels
    • Carro E, Trejo J, Gomez-Isla T, LeRoith D, Torres-Aleman I (2002) Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat Med 8, 1390-1397.
    • (2002) Nat Med , vol.8 , pp. 1390-1397
    • Carro, E.1    Trejo, J.2    Gomez-Isla, T.3    LeRoith, D.4    Torres-Aleman, I.5
  • 13
    • 28044466172 scopus 로고    scopus 로고
    • Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor i
    • Carro E, Trejo SC, Antequera JL, Torres-Aleman D, I (2005) Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I. J Neurosci 25, 10884-10893.
    • (2005) J Neurosci , vol.25 , pp. 10884-10893
    • Carro, E.1    Trejo, S.C.2    Antequera, J.L.3    Torres-Aleman, D.I.4
  • 14
    • 33644591150 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine
    • Rivera E, Goldin A, Fulmer N, Tavares R, Wands J, de la Monte S (2005) Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine. J Alzheimers Dis 8, 247-268.
    • (2005) J Alzheimers Dis , vol.8 , pp. 247-268
    • Rivera, E.1    Goldin, A.2    Fulmer, N.3    Tavares, R.4    Wands, J.5    De La Monte, S.6
  • 15
    • 15244351255 scopus 로고    scopus 로고
    • Impaired insulin and insulinlike growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?
    • Steen E, Terry B, Rivera E, Cannon J, Neely T, Tavares R, Xu X, Wands J, de la Monte S (2005) Impaired insulin and insulinlike growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimers Dis 7, 63-80.
    • (2005) J Alzheimers Dis , vol.7 , pp. 63-80
    • Steen, E.1    Terry, B.2    Rivera, E.3    Cannon, J.4    Neely, T.5    Tavares, R.6    Xu, X.7    Wands, J.8    De La Monte, S.9
  • 17
    • 84897370805 scopus 로고    scopus 로고
    • Changes in cerebrospinal fluid and blood plasma levels of IGF-II and its binding proteins in Alzheimer's disease: An observational study
    • Hertze J, Nägga K, Minthon L, Hansson O (2014) Changes in cerebrospinal fluid and blood plasma levels of IGF-II and its binding proteins in Alzheimer's disease: An observational study. BMC Neurol 14, 64.
    • (2014) BMC Neurol , vol.14 , pp. 64
    • Hertze, J.1    Nägga, K.2    Minthon, L.3    Hansson, O.4
  • 19
    • 79952116390 scopus 로고    scopus 로고
    • Leu27 insulin-like growth factor-II, an insulin-like growth factor-II analog, attenuates depolarization-evoked GABArelease from adult rat hippocampal and cortical slices
    • Amritraj A, Rauw G, Baker G, Kar S (2010) Leu27 insulin-like growth factor-II, an insulin-like growth factor-II analog, attenuates depolarization-evoked GABArelease from adult rat hippocampal and cortical slices. Neuroscience 170, 722-730.
    • (2010) Neuroscience , vol.170 , pp. 722-730
    • Amritraj, A.1    Rauw, G.2    Baker, G.3    Kar, S.4
  • 20
    • 84941731159 scopus 로고    scopus 로고
    • The role of IGF-I, IGF-II, and IGFBP-3 in male cognitive aging and dementia risk: The Caerphilly Prospective Study
    • Green C, Holly J, Bayer A, Fish M, Ebrahim S, Gallacher J, Ben-Shlomo Y (2014) The role of IGF-I, IGF-II, and IGFBP-3 in male cognitive aging and dementia risk: The Caerphilly Prospective Study. J Alzheimers Dis 41, 867-875.
    • (2014) J Alzheimers Dis , vol.41 , pp. 867-875
    • Green, C.1    Holly, J.2    Bayer, A.3    Fish, M.4    Ebrahim, S.5    Gallacher, J.6    Ben-Shlomo, Y.7
  • 22
    • 84873743958 scopus 로고    scopus 로고
    • Galantamine increases hippocampal insulin-like growth factor 2 expression via -7 nicotinic acetylcholine receptors in mice
    • Kita Y, Ago Y, Takano E, Fukada A, Takuma K, Matsuda T (2013) Galantamine increases hippocampal insulin-like growth factor 2 expression via -7 nicotinic acetylcholine receptors in mice. Psychopharmacology (Berl) 225, 543-551.
    • (2013) Psychopharmacology (Berl) , vol.225 , pp. 543-551
    • Kita, Y.1    Ago, Y.2    Takano, E.3    Fukada, A.4    Takuma, K.5    Matsuda, T.6
  • 24
    • 84904462332 scopus 로고    scopus 로고
    • Enhancement of memories by systemic administration of insulin-like qrowth factor II
    • Stern S, Kohtz A, Pollonini G, Alberini C (2014) Enhancement of memories by systemic administration of insulin-like qrowth factor II. Neuropsychopharmacology 39, 2179-2190.
    • (2014) Neuropsychopharmacology , vol.39 , pp. 2179-2190
    • Stern, S.1    Kohtz, A.2    Pollonini, G.3    Alberini, C.4
  • 25
    • 84899621158 scopus 로고    scopus 로고
    • IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice
    • Mellott T, Pender S, Burke R, Langley E, Blusztajn J (2014) IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. PLoS One 9, e94287.
    • (2014) PLoS One , vol.9 , pp. e94287
    • Mellott, T.1    Pender, S.2    Burke, R.3    Langley, E.4    Blusztajn, J.5
  • 27
    • 1842633868 scopus 로고    scopus 로고
    • The role of insulin and insulin-like growth factor i in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease
    • Carro E, Torres-Aleman I (2004) The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease. Eur J Pharmacol 490, 127-133.
    • (2004) Eur J Pharmacol , vol.490 , pp. 127-133
    • Carro, E.1    Torres-Aleman, I.2
  • 30
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDAWork Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDAWork Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 33
    • 4544335597 scopus 로고    scopus 로고
    • Mild cognitive impairment as a diagnostic entity
    • Petersen R (2004) Mild cognitive impairment as a diagnostic entity. J Intern Med 256, 183-194.
    • (2004) J Intern Med , vol.256 , pp. 183-194
    • Petersen, R.1
  • 34
    • 0016823810 scopus 로고
    • Mini-mental state. A practical method for grading the cognitive state of patients for the clinician
    • Folstein M, Folstein S, McHugh P (1975) Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.1    Folstein, S.2    McHugh, P.3
  • 36
    • 0029609264 scopus 로고
    • Tau protein in cerebrospinal fluid: A biochemical marker for axonal degeneration in Alzheimer disease?
    • Blennow K, Wallin A, Agren H, Spenger C, Siegfried J, Vanmechelen E (1995) Tau protein in cerebrospinal fluid: A biochemical marker for axonal degeneration in Alzheimer disease? Mol Chem Neuropathol 26, 231-245.
    • (1995) Mol Chem Neuropathol , vol.26 , pp. 231-245
    • Blennow, K.1    Wallin, A.2    Agren, H.3    Spenger, C.4    Siegfried, J.5    Vanmechelen, E.6
  • 38
    • 0027993236 scopus 로고
    • Coordinated pattern of expression and localization of insulin-like growth factor-II (IGF-II) and IGFbinding protein-2 in the adult rat brain
    • Logan A, Gonzalez A, Hill D, Berry M, Gregson N, Baird A (1994) Coordinated pattern of expression and localization of insulin-like growth factor-II (IGF-II) and IGFbinding protein-2 in the adult rat brain. Endocrinology 135, 2255-2264.
    • (1994) Endocrinology , vol.135 , pp. 2255-2264
    • Logan, A.1    Gonzalez, A.2    Hill, D.3    Berry, M.4    Gregson, N.5    Baird, A.6
  • 39
    • 0022506238 scopus 로고
    • Binding and internalization of insulin and insulin-like growth factors by isolated brain microvessels
    • Frank H, PardridgeW, MorrisW, Rosenfeld R, Choi T (1986) Binding and internalization of insulin and insulin-like growth factors by isolated brain microvessels. Diabetes 35, 654-661.
    • (1986) Diabetes , vol.35 , pp. 654-661
    • Frank, H.1    Pardridge, W.2    Morris, W.3    Rosenfeld, R.4    Choi, T.5
  • 41
  • 42
    • 0035049816 scopus 로고    scopus 로고
    • Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2
    • Hoeflich A, Nedbal S, Blum W, Erhard M, Lahm H, Brem G, Kolb H, Wanke R, Wolf E (2001) Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2. Endocrinology 142, 1889-1898.
    • (2001) Endocrinology , vol.142 , pp. 1889-1898
    • Hoeflich, A.1    Nedbal, S.2    Blum, W.3    Erhard, M.4    Lahm, H.5    Brem, G.6    Kolb, H.7    Wanke, R.8    Wolf, E.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.