Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor

NeuroToxicology

Volumn 51, Issue , 2015, Pages 80-86

  Rauh, Virginia A ^a   Garcia, Wanda E ^a   Whyatt, Robin M ^a   Horton, Megan K ^b   Barr, Dana B ^c   Louis, Elan D ^d,e  

^a Department of Medicine   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e YALE UNIVERSITY   (United States)

Author keywords

Brain; Children; Chlorpyrifos; Neurodevelopment; Tremor

Indexed keywords

CHLORPYRIFOS; ORGANOPHOSPHATE PESTICIDE; INSECTICIDE;

ADOLESCENT; ADULT; AGE; ARTICLE; BLOOD SAMPLING; CHILD; CHILDHOOD DISEASE; COHORT ANALYSIS; DISEASE SEVERITY; DRUG USE; ETHNICITY; FEMALE; HUMAN; MALE; NERVOUS SYSTEM DEVELOPMENT; NERVOUS SYSTEM FUNCTION; NEUROPSYCHOLOGICAL TEST; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; TREMOR; UMBILICAL CORD BLOOD; UNITED STATES; ADVERSE EFFECTS; BLOOD; CHEMICALLY INDUCED; CHEMISTRY; FETOMATERNAL TRANSFUSION; FETUS BLOOD; MATERNAL EXPOSURE; PATHOPHYSIOLOGY; PREGNANCY;

ADOLESCENT; CHILD; CHLORPYRIFOS; FEMALE; FETAL BLOOD; HUMANS; INSECTICIDES; MALE; MATERNAL EXPOSURE; MATERNAL-FETAL EXCHANGE; NEUROPSYCHOLOGICAL TESTS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; TREMOR;

EID: 84943785591     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2015.09.004     Document Type: Article

References (47)

1. Abou-Donia M.B., Khan W.A., Dechkovskaia A.M., Goldstein L.B., Bullman S.L., Abdel-Rahman A.A. In utero exposure to nicotine and chlorpyrifos, alone and in combination produced persistent sensorimotor deficits and Purkinje neuronal loss in the cerebellum of adult offspring rats. J. Toxicol. Environ. Health 2006, 80:620-631.
2. Accury T.A., Grzywacz, Barr D.B., Tapia J., Chen H., Quandt S.A. Pesticide urinary metabolite levels of children in eastern North Carolina farmworker households. Environ. Health Perspect. 2007, 115(7):1254-1260.
3. Aldridge J.E., Meyer A., Seidler F.J., Slotkin T.A. Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure. Environ. Health Perspect. 2005, 113:1027-1031.
4. Barr D.B., Barr J.R., Maggio V.L., Whitehead R.D., Sadowski M.A., Whyatt R.M., Needham L.L. A multi-analyte method for the quantification of contemporary pesticides in human serum and plasma using high resolution mass spectrometry. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2002, 778:99-111.
5. Berkowitz G.S., Obel J., Deych E., Lapinski R., Godbold J., Liu Z., et al. Exposure to indoor pesticides during pregnancy in a multiethnic, urban cohort. Environ. Health Perspect. 2003, 111:79-84.
6. Bouchard M.F., Chevrier J., Harley K.G., Kogut K., Vedar M., Calderon N., Trujillo C., Johnson C., Bradman A., Barr D.B., Eskenazi B. Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children. Environ. Health Perspect. 2011, 119(August (8)):1189-1195.
7. Bradman A., Barr D.B., Claus Henn B.G., Drumheller T., Curry C., Eskenazi B. Measurement of pesticides and other toxicants in amnionic fluid as a potential biomarker of prenatal exposure: a validation study. Environ. Health Perspect. 2003, 113:1802-1807.
8. Bradman A., Whitaker D., Quirós L., Castorina R., Henn B.C., Nishioka M., et al. Pesticides and their metabolites in the homes and urine of farmworker children living in the Salinas Valley, CA. J. Expo. Sci. Environ. Epidemiol. 2007, 17:331-349.
9. Dam K., Garcia S.J., Seidler F.J., Slotkin T.A. Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathways. Dev. Brain Res. 1999, 116:9-20.
10. Deuschl G., Bain P., Brin M. Consensus statement of the movement disorder society on tremor. Ad hoc Scientific Committee. Mov. Disord. 1998, 13(Suppl. 3):2-23.
11. Dogu O., Louis E.D., Tamer L., Unal O., Yilmaz A., Kaleagasi H. Elevated blood lead concentrations in essential tremor: a case-control study in Mersin, Turkey. Environ. Health Perspect. 2007, 115(November (11)):1564-1568.
12. Engel S.M., Berkowitz G.S., Barr D.B., Teitelbaum S.L., Siskind J., Meisel S.L., et al. Prenatal organophosphate metabolite and organochlorine levels and performance on the Brazelton Neonatal Behavioral Assessment Scale in a multiethnic pregnancy cohort. Am. J. Epidemiol. 2007, 165:1397-1404.
13. Engel S.M., Wetmur J., Chen J., Zhu C., Barr D.B., Canfield R.L., Wolff M.S. Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood. Environ. Health Perspect. 2011, 119(August (8)):1182-1188.
14. Eskenazi B., Marks A.R., Bradman A., Harley K., Barr D.B., Johnson C., et al. Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children. Environ. Health Perspect. 2007, 115:792-798.
15. Furlong M.A., Engel S.M., Barr D.B., Wolff M.S. Prenatal exposure to organophosphate pesticides and reciprocal social behavior in childhood. Environ. Int. 2014, 70:125-131.
16. Grube A., Donaldson D., Kiely T., Wu L. Pesticide Industry Sales and Usage: 2006 and 2007 Market Estimates. United States Environmental Protection Agency, Office of Pesticide Programs, Biological and Economic Analysis Division, Washington, DC. EPA 733-R-11-001 2011.
17. Jiménez-Jiménez F.J., de Toledo-Heras M., Alonso-Navarro H., Ayuso-Peralta L., Arévalo-Serrano J., Ballesteros-Barranco A., Puertas I., Jabbour-Wadih T., Barcenilla B. Environmental risk factors for essential tremor. Eur. Neurol. 2007, 58(2):106-113.
18. Levin E.D., Addy N., Baruah A., Elias A., Cannelle Christopher N., Seidler F.J., Slotlin T.A. Prenatal chlorpyrifos exposure in rats causes persistent behavioral alternations. Neurotoxicol. Teratol. 2002, 24:733-741.
19. Lieberman A.I.S., Brewer M., et al. High prevalence of tremor in a retirement community. Neurology 1994, 44:A213.
20. Louis E.D., Ford B., Pullman S., Baron K. How normal is 'normal'? Mild tremor in a multiethnic cohort of normal subjects. Arch. Neurol. 1998, 55:222-227.
21. Louis E.D., Wendt K.J., Ford B. Senile tremor. What is the prevalence and severity of tremor in older adults?. Gerontology 2000, 46:12-16.
22. Louis E.D., Zheng W., Jurewicz E.C., Watner D.D., Chen J., Factor-Litvak P., Parides M. Elevation of blood β-carboline alkaloids in essential tremor. Neurology 2002, 59:1940-1944.
23. Louis E.D., Jurewicz E.C., Applegate L., Factor-Litvak P., Parides M., Andrews L., Slavkovich V., Graziano J.H., Carroll S., Todd A. Association between essential tremor and blood lead concentration. Environ. Health Perspect. 2003, 111(November (14)):1707-1711.
24. Louis E.D., Factor-Litvak P., Parides M., Andrews L., Santella R.M., Wolff M.S. Organochlorine pesticide exposure in essential tremor: a case-control study using biological and occupational exposure assessments. Neurotoxicology 2006, 27(July (4)):579-586.
25. Louis E.D., Cubo E., Trejo-Gabriel-Galan J.M., et al. Tremor in school-aged children: a cross-sectional study of tremor in 819 boys and girls in Burgos, Spain. Neuroepidemiology 2011, 37:90-95.
26. Louis E.D., Zhao Q., Meng H., Ding D. Screening for action tremor in epidemiological field surveys: assessing the reliability of a semi-quantitative, visual, template-based scale for rating hand-drawn spirals. Tremor Other Hyperkinet. Mov. (NY) 2012, 2. pii: tre-02-46-177-2.
27. Louis E.D., Garcia W.E., Rauh V.A. Tremor in a population-based cohort of children in New York City. Pediatr. Neurol. 2015, 52(February (2)):187-191.
28. Marks A.R., Harley K., Bradman A., Kogut K., Barr D.B., Johnson C., et al. Organophosphate pesticide exposure and attention in young Mexican-American children: the CHAMACOS study. Environ. Health Perspect. 2010, 118:1768-1774.
29. Perera F.P., Illman S.M., Kinney P.L., Whyatt R.M., Kelvin E.A., Shepard P., et al. The challenge of preventing environmentally related disease in young children: community-based research in New York City. Environ. Health Perspect. 2002, 110:197-204.
30. Qiao D., Seidler F.J., Abreu-Villaça Y., Tate C.A., Cousins M.M., Slotkin T.A. Chlorpyrifos exposure during neurulation: cholinergic synaptic dysfunction and cellular alterations in brain regions at adolescence and adulthood. Dev. Brain Res. 2004, 148:43-52.
31. Rauh V.A., Garfinkel R., Perera F.P., Andrews H., Barr D., Whitehead D., et al. Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first three years of life among inner-city children. Pediatrics 2006, 118:e1845-e1859.
32. Rauh V., Arunajadai S., Horton M., et al. Seven-year neurodevelopmental scores and prenatal exposure to chlorpyrifos, a common agricultural pesticide. Environ. Health Perspect. 2011, 119:1196-1201.
33. Rauh V.A., Perera F.P., Horton M.K., Whyatt R.M., Bansal R., Hao X., Liu J., Barr D.B., Slotkin T.A., Peterson B.S. Brain anomalies in children exposed prenatally to a common organophosphate pesticide. Proc. Natl. Acad. Sci. U. S. A. 2012, 109(15 May (20)):7871-7876.
34. Richardson R.J. Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorus compounds: a critical review of the literature. J. Toxicol. Environ. Health 1995, 44:135-165.
35. Slotkin T.A. Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates. Toxicol. Appl. Pharmacol. 2004, 198:132-151.
36. Slotkin T.A., Seidler F.J. The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent. Dev. Brain Res. 2005, 158:115-119.
37. Slotkin T.A., Tate C.A., Cousins M.M., Seidler F.J. Functional alterations in CNS catecholamine systems in adolescence and adulthood after neonatal chlorpyrifos exposure. Dev. Brain Res. 2002, 133:163-173.
38. Solomon K.R., Williams W.M., Mackay D., Purdy J., Giddings J.M., Giesy J.P. Properties and uses of chlorpyrifos in the United States. Rev. Environ. Contam. Toxicol. 2014, 231:13-34.
39. Tiffin J. Purdue Pegboard Examiner Manual 1968, Science Research Association, Chicago, IL.
40. Unites States Environmental Protection and Agency Chlorpyrifos Revised Risk Assessment and Agreement with Registrants. Washington, DC 2000.
41. United States Environmental Protection Agency Environmental Protection and Agency Chlorpyrifos End-use Products Cancellation Order. Washington, DC 2002.
42. Whyatt R.M., Barr D.B., Camann D.E., Kinney P.L., Barr J.R., Andrews H.F., et al. Contemporary-use pesticides in personal air samples during pregnancy and blood samples at delivery among urban minority mothers and newborns. Environ. Health Perspect. 2003, 111:749-756.
43. Whyatt R.M., Rauh V., Barr D.B., Camann D.E., Andrews H.F., Garfinkel R., Hoepner L.A., Diaz D., Dietrich J., Reyes A., Tang D., Kinney P.L., Perera F.P. Prenatal insecticide exposure and birth weight and length among an urban minority cohort. Environ. Health Perspect. 2004, 112:1125-1132.
44. Whyatt R.M., Camann D., Perera F.P., Rauh V.A., Tang D., Kinney P.L., et al. Biomarkers in assessing residential insecticide exposures during pregnancy and effects on fetal growth. Toxicol. Appl. Pharmacol. 2005, 206:246-254.
45. Whyatt R.M., Garfinkel R., Hoepner L.A., Holmes D., Borjas M., Perera F.P., et al. Within and between home variability in indoor-air insecticide levels during pregnancy among an inner-city cohort from New York City. Environ. Health Perspect. 2007, 115:383-390.
46. Young J.G., Eskenazi B., Gladstone E.A., Bradman A., Pedersen L., Johnson C., et al. Association between in utero organophosphate exposure and abnormal reflexes in neonates. Neurotoxicology 2005, 26:199-209.
47. Zhang Y., Han S., Liang D., et al. Prenatal exposure to organophosphate pesticides and neurobehavioral development of neonates: a birth cohort study in Shenyang, China. PLOS ONE 2014, 9(2):e88491.