SCOPUS 정보 검색 플랫폼

Volumn 51, Issue 84, 2015, Pages 15458-15461

Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases

(18) Thinnes, C C a Tumber, A b Yapp, C b Scozzafava, G b Yeh, T a,b Chan, M C b Tran, T A c Hsu, K a Tarhonskaya, H a Walport, L J a Wilkins, S E a Martinez, E D c Muller S b Pugh, C W b Ratcliffe, P J b Brennan, P E b Kawamura, A a,d Schofield, C J a

a UNIVERSITY OF OXFORD (United Kingdom)

b UNIVERSITY OF OXFORD (United Kingdom)

c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (United States)

d UNIVERSITY OF OXFORD (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOPHENOL; 2 OXOGLUTARATE OXYGENASE INHIBITOR; 2 OXOGLUTARIC ACID; 8 QUINOLINOL; ACROLEIN; AMIDE; FERROUS ION; HISTONE DEMETHYLASE; HYPOXIA INDUCIBLE FACTOR 2ALPHA; KDM4 HISTONE DEMETHYLASE; NUCLEOPHILE; OXYGENASE INHIBITOR; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; SODIUM DITHIONITE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; OXYGENASE;

ARTICLE; BETTI REACTION; BINDING SITE; BREAST CANCER CELL LINE; CATALYSIS; CHEMICAL REACTION; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; HYDROXYLATION; IMMUNOFLUORESCENCE TEST; LUNG CANCER CELL LINE; MANNICH REACTION; MASS SPECTROMETRY; NUCLEOPHILICITY; ONE POT SYNTHESIS; SKRAUP CONDENSATION; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; UPREGULATION; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; METABOLISM; SYNTHESIS;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OXYGENASES; OXYQUINOLINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84943784924 PISSN: 13597345 EISSN: 1364548X Source Type: Journal
DOI: 10.1039/c5cc06095h Document Type: Article

Times cited : (37)

References (17)

1
- 77249142404
- S. V. Frye Nat. Chem. Biol. 2010 6 159 161
- (2010) Nat. Chem. Biol. , vol.6 , pp. 159-161
- Frye, S.V.¹

2
- 39349105090
- C. Loenarz C. J. Schofield Nat. Chem. Biol. 2008 4 152 156
- (2008) Nat. Chem. Biol. , vol.4 , pp. 152-156
- Loenarz, C.¹ Schofield, C.J.²

3
- 84889573275
- J. W. Hojfeldt K. Agger K. Helin Nat. Rev. Drug Discovery 2013 12 917 930
- (2013) Nat. Rev. Drug Discovery , vol.12 , pp. 917-930
- Hojfeldt, J.W.¹ Agger, K.² Helin, K.³

4
- 84914118716
- C. C. Thinnes K. S. England A. Kawamura R. Chowdhury C. J. Schofield R. J. Hopkinson BBA, Biochim. Biophys. Acta, Gene Regul. Mech. 2014 1839 1416 1432
- (2014) BBA, Biochim. Biophys. Acta, Gene Regul. Mech. , vol.1839 , pp. 1416-1432
- Thinnes, C.C.¹ England, K.S.² Kawamura, A.³ Chowdhury, R.⁴ Schofield, C.J.⁵ Hopkinson, R.J.⁶

5
- 84877861510
- W. L. Berry R. Janknecht Cancer Res. 2013 73 2936 2942
- (2013) Cancer Res. , vol.73 , pp. 2936-2942
- Berry, W.L.¹ Janknecht, R.²

6
- 33645891676
- I. J. Clifton M. A. McDonough D. Ehrismann N. J. Kershaw N. Granatino C. J. Schofield J. Inorg. Biochem. 2006 100 644 669
- (2006) J. Inorg. Biochem. , vol.100 , pp. 644-669
- Clifton, I.J.¹ McDonough, M.A.² Ehrismann, D.³ Kershaw, N.J.⁴ Granatino, N.⁵ Schofield, C.J.⁶

7
- 79956220088
- N. R. Rose M. A. McDonough O. N. F. King A. Kawamura C. J. Schofield Chem. Soc. Rev. 2011 40 4364 4397
- (2011) Chem. Soc. Rev. , vol.40 , pp. 4364-4397
- Rose, N.R.¹ McDonough, M.A.² King, O.N.F.³ Kawamura, A.⁴ Schofield, C.J.⁵

8
- 78649528262
- O. N. F. King X. S. Li M. Sakurai A. Kawamura N. R. Rose S. S. S. Ng A. M. Quinn G. Rai B. T. Mott P. Beswick R. J. Klose U. Oppermann A. Jadhav T. D. Heightman D. J. Maloney C. J. Schofield A. Simeonov PLoS One 2010 5 e15535
- (2010) PLoS One , vol.5 , pp. e15535
- King, O.N.F.¹ Li, X.S.² Sakurai, M.³ Kawamura, A.⁴ Rose, N.R.⁵ Ng, S.S.S.⁶ Quinn, A.M.⁷ Rai, G.⁸ Mott, B.T.⁹ Beswick, P.¹⁰ Klose, R.J.¹¹ Oppermann, U.¹² Jadhav, A.¹³ Heightman, T.D.¹⁴ Maloney, D.J.¹⁵ Schofield, C.J.¹⁶ Simeonov, A.¹⁷

9
- 84880016971
- R. J. Hopkinson A. Tumber C. Yapp R. Chowdhury W. Aik K. H. Che X. S. Li J. B. L. Kristensen O. N. F. King M. C. Chan K. K. Yeoh H. Choi L. J. Walport C. C. Thinnes J. T. Bush C. Lejeune A. M. Rydzik N. R. Rose E. A. Bagg M. A. McDonough T. J. Krojer W. W. Yue S. S. Ng L. Olsen P. E. Brennan U. Oppermann S. Muller R. J. Klose P. J. Ratcliffe C. J. Schofield A. Kawamura Chem. Sci. 2013 4 3110 3117
- (2013) Chem. Sci. , vol.4 , pp. 3110-3117
- Hopkinson, R.J.¹ Tumber, A.² Yapp, C.³ Chowdhury, R.⁴ Aik, W.⁵ Che, K.H.⁶ Li, X.S.⁷ Kristensen, J.B.L.⁸ King, O.N.F.⁹ Chan, M.C.¹⁰ Yeoh, K.K.¹¹ Choi, H.¹² Walport, L.J.¹³ Thinnes, C.C.¹⁴ Bush, J.T.¹⁵ Lejeune, C.¹⁶ Rydzik, A.M.¹⁷ Rose, N.R.¹⁸ Bagg, E.A.¹⁹ McDonough, M.A.²⁰ more..

10
- 77950936168
- N. A. Smirnova I. Rakhman N. Moroz M. Basso J. Payappilly S. Kazakov F. Hernandez-Guzman I. N. Gaisina A. P. Kozikowski R. R. Ratan I. G. Gazaryan Chem. Biol. 2010 17 380 391
- (2010) Chem. Biol. , vol.17 , pp. 380-391
- Smirnova, N.A.¹ Rakhman, I.² Moroz, N.³ Basso, M.⁴ Payappilly, J.⁵ Kazakov, S.⁶ Hernandez-Guzman, F.⁷ Gaisina, I.N.⁸ Kozikowski, A.P.⁹ Ratan, R.R.¹⁰ Gazaryan, I.G.¹¹

11
- 77953135942
- C. Cardellicchio M. A. M. Capozzi F. Naso Tetrahedron: Asymmetry 2010 21 507 517
- (2010) Tetrahedron: Asymmetry , vol.21 , pp. 507-517
- Cardellicchio, C.¹ Capozzi, M.A.M.² Naso, F.³

12
- 79961219253
- V. Kenyon G. Rai A. Jadhav L. Schultz M. Armstrong J. B. Jameson S. Perry N. Joshi J. M. Bougie W. Leister D. A. Taylor-Fishwick J. L. Nadler M. Holinstat A. Simeonov D. J. Maloney T. R. Holman J. Med. Chem. 2011 54 5485 5497
- (2011) J. Med. Chem. , vol.54 , pp. 5485-5497
- Kenyon, V.¹ Rai, G.² Jadhav, A.³ Schultz, L.⁴ Armstrong, M.⁵ Jameson, J.B.⁶ Perry, S.⁷ Joshi, N.⁸ Bougie, J.M.⁹ Leister, W.¹⁰ Taylor-Fishwick, D.A.¹¹ Nadler, J.L.¹² Holinstat, M.¹³ Simeonov, A.¹⁴ Maloney, D.J.¹⁵ Holman, T.R.¹⁶

13
- 84943740969
- M. G. Bursavich, J. J. Clemens, A. M. Gilbert, D. B. How, G. Khafizova, L. M. Laakso, S. Lombardi, J. J. Sabatini and P.-E. Sum, Int. Pat., WO2008024922, 2008
- (2008) Int. Pat.
- Bursavich, M.G.¹ Clemens, J.J.² Gilbert, A.M.³ How, D.B.⁴ Khafizova, G.⁵ Laakso, L.M.⁶ Lombardi, S.⁷ Sabatini, J.J.⁸ Sum, P.-E.⁹

14
- 84869871771
- I. Hoffmann M. Roatsch M. L. Schmitt L. Carlino M. Pippel W. Sippl M. Jung Mol. Oncol. 2012 6 683 703
- (2012) Mol. Oncol. , vol.6 , pp. 683-703
- Hoffmann, I.¹ Roatsch, M.² Schmitt, M.L.³ Carlino, L.⁴ Pippel, M.⁵ Sippl, W.⁶ Jung, M.⁷

15
- 84889595831
- L. Wang J. Chang D. Varghese M. Dellinger S. Kumar A. M. Best J. Ruiz R. Bruick S. Peña-Llopis J. Xu D. J. Babinski D. E. Frantz R. A. Brekken A. M. Quinn A. Simeonov J. Easmon E. D. Martinez Nat. Commun. 2013 4 2035
- (2013) Nat. Commun. , vol.4 , pp. 2035
- Wang, L.¹ Chang, J.² Varghese, D.³ Dellinger, M.⁴ Kumar, S.⁵ Best, A.M.⁶ Ruiz, J.⁷ Bruick, R.⁸ Peña-Llopis, S.⁹ Xu, J.¹⁰ Babinski, D.J.¹¹ Frantz, D.E.¹² Brekken, R.A.¹³ Quinn, A.M.¹⁴ Simeonov, A.¹⁵ Easmon, J.¹⁶ Martinez, E.D.¹⁷

16
- 4043119692
- K. S. Hewitson C. J. Schofield Drug Discovery Today 2004 9 704 711
- (2004) Drug Discovery Today , vol.9 , pp. 704-711
- Hewitson, K.S.¹ Schofield, C.J.²

17
- 84880534866
- R. Chowdhury J. I. Candela-Lena M. C. Chan D. J. Greenald K. K. Yeoh Y.-M. Tian M. A. McDonough A. Tumber N. R. Rose A. Conejo-Garcia M. Demetriades S. Mathavan A. Kawamura M. K. Lee F. van Eeden C. W. Pugh P. J. Ratciffe C. J. Schofield ACS Chem. Biol. 2013 8 1488 1496
- (2013) ACS Chem. Biol. , vol.8 , pp. 1488-1496
- Chowdhury, R.¹ Candela-Lena, J.I.² Chan, M.C.³ Greenald, D.J.⁴ Yeoh, K.K.⁵ Tian, Y.-M.⁶ McDonough, M.A.⁷ Tumber, A.⁸ Rose, N.R.⁹ Conejo-Garcia, A.¹⁰ Demetriades, M.¹¹ Mathavan, S.¹² Kawamura, A.¹³ Lee, M.K.¹⁴ Van Eeden, F.¹⁵ Pugh, C.W.¹⁶ Ratciffe, P.J.¹⁷ Schofield, C.J.¹⁸

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.