Bone mineral accrual is associated with parathyroid hormone and 1,25-dihydroxyVitamin D levels in children and adolescents

Journal of Clinical Endocrinology and Metabolism

Volumn 100, Issue 10, 2015, Pages 3814-3821

  DeBoer, Mark D ^a   Weber, David R ^b   Zemel, Babette S ^b   Denburg, Michelle R ^b   Herskovitz, Rita ^c   Long, Jin ^b   Leonard, Mary B ^d  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; PARATHYROID HORMONE; 1,25-DIHYDROXYVITAMIN D; VITAMIN D;

ADOLESCENT; ADULT; ARTICLE; BONE MINERAL; BONE MINERAL ACCRUAL; CALCIUM ABSORPTION; CALCIUM INTAKE; CHILD; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; LONGITUDINAL STUDY; MALE; NORMAL HUMAN; OSSIFICATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; TIBIA; VITAMIN BLOOD LEVEL; ANALOGS AND DERIVATIVES; BLOOD; BONE DENSITY; BONE DEVELOPMENT; BONE MINERALIZATION; PHYSIOLOGY; PRESCHOOL CHILD; PUBERTY; YOUNG ADULT;

ADOLESCENT; BONE DENSITY; BONE DEVELOPMENT; CALCIFICATION, PHYSIOLOGIC; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; MALE; PARATHYROID HORMONE; PUBERTY; VITAMIN D; YOUNG ADULT;

EID: 84943740585     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2015-1637     Document Type: Article

References (29)

1. Whiting SJ, Vatanparast H, Baxter-Jones A, Faulkner RA, Mirwald R, Bailey DA. Factors that affect bone mineral accrual in the adolescent growth spurt. J Nutr. 2004;134:696S-700S.
2. McKay HA, Bailey DA, Mirwald RL, Davison KS, Faulkner RA. Peak bone mineral accrual and age at menarche in adolescent girls: A 6-year longitudinal study. J Pediatr. 1998;133:682-687.
3. Baxter-Jones AD, Faulkner RA, Forwood MR, Mirwald RL, Bailey DA. Bone mineral accrual from 8 to 30 years of age: an estimation of peak bone mass. J Bone Miner Res. 2011;26:1729-1739.
4. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266-281.
5. Kumar R, Tebben PJ, Thompson JR. Vitamin D and the kidney. Arch Biochem Biophys. 2012;523:77-86.
6. Chapuy MC, Preziosi P, Maamer M, et al. Prevalence of Vitamin D insufficiency in an adult normal population. Osteoporos Int. 1997; 7:439-443.
7. Ginde AA, Wolfe P, Camargo CA Jr, Schwartz RS. Defining Vitamin D status by secondary hyperparathyroidism in the U.S. population. J Endocrinol Invest. 2012;35:42-48.
8. Weng FL, Shults J, Leonard MB, Stallings VA, Zemel BS. Risk factors for low serum 25-hydroxyVitamin D concentrations in otherwise healthy children and adolescents. Am J Clin Nutr. 2007;86: 150-158.
9. Warden SJ, Hill KM, Ferira AJ, et al. Racial differences in cortical bone and their relationship to biochemical variables in black and white children in the early stages of puberty. Osteoporos Int. 2013; 24:1869-1879.
10. Steingrimsdottir L, Gunnarsson O, Indridason OS, Franzson L, Sigurdsson G. Relationship between serum parathyroid hormone levels, Vitamin D sufficiency, and calcium intake. JAMA. 2005;294: 2336-2341.
11. Chapuy MC, Arlot ME, Duboeuf F, et al. Vitamin D3 and calcium to prevent hip fractures in the elderly women. N Engl J Med. 1992; 327:1637-1642.
12. Lewiecki EM, Miller PD. Skeletal effects of primary hyperparathyroidism: bone mineral density and fracture risk. J Clin Densitom. 2013;16:28-32.
13. Abrams SA, Griffin IJ, Hawthorne KM, Gunn SK, Gundberg CM, Carpenter TO. Relationships among Vitamin D levels, parathyroid hormone, and calcium absorption in young adolescents. J Clin Endocrinol Metab. 2005;90:5576-5581.
14. Leonard MB, Elmi A, Mostoufi-Moab S, et al. Effects of sex, race, and puberty on cortical bone and the functional muscle bone unit in children, adolescents, and young adults. J Clin Endocrinol Metab. 2010;95:1681-1689.
15. Tuchman S, Thayu M, Shults J, Zemel BS, Burnham JM, Leonard MB. Interpretation of biomarkers of bone metabolism in children: impact of growth velocity and body size in healthy children and chronic disease. J Pediatr. 2008;153:484-490.
16. Morris NM, Udry JR. Validation of a self-administered instrument to assess stage of adolescent development. J Youth Adolesc. 1980; 9:271-280.
17. Augustine MV, Leonard MB, Thayu M, et al. Changes in Vitamin D-related mineral metabolism after induction with anti-tumor necrosis factor-therapy in Crohn's disease. J Clin Endocrinol Metab. 2014;99:E991-E998.
18. Cremers S, Garnero P. Biochemical markers of bone turnover in the clinical development of drugs for osteoporosis and metastatic bone disease: potential uses and pitfalls. Drugs. 2006;66:2031-2058.
19. Szulc P, Seeman E, Delmas PD. Biochemical measurements of bone turnover in children and adolescents. Osteoporos Int. 2000;11:281-294.
20. Hollis BW. Quantitation of 25-hydroxyVitamin D and 1,25-dihydroxyvitaminDby radioimmunoassay using radioiodinated tracers. Methods Enzymol. 1997;282:174-186.
21. Smiciklas-Wright HA, Mitchell DC, Norton LD, Derr JA. Interviewer reliability of nutrient intake data from 24-hour recalls collected using the Minnesota Nutrition Data System (NDS). JAmDiet Assoc. 1991;91:A28.
22. Kuczmarski RJ, Ogden CL, Guo SS, et al. 2000 CDC growth charts for the United States: methods and development. Vital Health Stat 11. 2002:1-190.
23. Schweizer R, Martin DD, Schwarze CP, et al. Cortical bone density is normal in prepubertal children with growth hormone (GH) deficiency, but initially decreases during GH replacement due to early bone remodeling. J Clin Endocrinol Metab. 2003;88:5266-5272.
24. Mostoufi-Moab S, Brodsky J, Isaacoff EJ, et al. Longitudinal assessment of bone density and structure in childhood survivors of acute lymphoblastic leukemia without cranial radiation. J Clin Endocrinol Metab. 2012;97:3584-3592.
25. Griffin LM, Thayu M, Baldassano RN, et al. Improvements in bone density and structure during anti-TNF-therapy in pediatric Crohn's disease. J Clin Endocrinol Metab. 2015;100:2630-2639.
26. Callewaert F, Sinnesael M, Gielen E, Boonen S, Vanderschueren D. Skeletal sexual dimorphism: relative contribution of sex steroids, GH-IGF1, and mechanical loading. J Endocrinol. 2010;207:127-134.
27. Callewaert F, Venken K, Kopchick JJ, et al. Sexual dimorphism in cortical bone size and strength but not density is determined by independent and time-specific actions of sex steroids and IGF-1: evidence from pubertal mouse models. J Bone Miner Res. 2010;25: 617-626.
28. Greenberg C, Kukreja SC, Bowser EN, Hargis GK, Henderson WJ, Williams GA. Parathyroid hormone secretion: effect of estradiol and progesterone. Metabolism. 1987;36:151-154.
29. Vincent A, Riggs BL, Atkinson EJ, Oberg AL, Khosla S. Effect of estrogen replacement therapy on parathyroid hormone secretion in elderly postmenopausal women. Menopause. 2003;10:165-171.