The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer

International Journal of Cancer

Volumn 137, Issue 12, 2015, Pages 2846-2857

  Wichmann, Gunnar ^a,b   Rosolowski, Maciej ^b   Krohn, Knut ^a   Kreuz, Markus ^b   Boehm, Andreas ^a   Reiche, Anett ^a   Scharrer, Ulrike ^a,b   Halama, Dirk ^a   Bertolini, Julia ^a   Bauer, Ulrike ^a   Holzinger, Dana ^c   Pawlita, Michael ^c   Hess, Jochen ^c,d   Engel, Christoph ^b   Hasenclever, Dirk ^b   Scholz, Markus ^b   Ahnert, Peter ^b   Kirsten, Holger ^b   Hemprich, Alexander ^a   Wittekind, Christian ^a   Herbarth, Olf ^b   Horn, Friedemann ^a,b   Dietz, Andreas ^a,b   Loeffler, Markus ^b   more..

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

APC; consensus clustering; gene expression; head and neck squamous cell carcinoma; human papillomavirus; neck metastasis; TP53

Indexed keywords

APC PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; PROTEIN P53; VIRUS DNA; VIRUS RNA; TP53 PROTEIN, HUMAN;

APC GENE; ARTICLE; CANCER PROGNOSIS; CANCER SURVIVAL; CARCINOGENESIS; COHORT ANALYSIS; CONTROLLED STUDY; DNA TRANSCRIPTION; GENE DISRUPTION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN TISSUE; IMMUNE RESPONSE; LYMPH NODE METASTASIS; LYMPHOCYTE ACTIVATION; NONHUMAN; OBSERVATIONAL STUDY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RNA TRANSCRIPTION; TP53 GENE; UPREGULATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HEAD AND NECK TUMOR; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MORTALITY; MUTATION; PAPILLOMAVIRUS INFECTION; PATHOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; SECONDARY; SQUAMOUS CELL CARCINOMA; VIROLOGY;

CARCINOMA, SQUAMOUS CELL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE FREQUENCY; HEAD AND NECK NEOPLASMS; HUMAN PAPILLOMAVIRUS 16; HUMANS; IMMUNITY, INNATE; LYMPHATIC METASTASIS; MUTATION; PAPILLOMAVIRUS INFECTIONS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RNA, VIRAL; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84943660309     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29649     Document Type: Article

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