Identification of an oncogenic RAB protein

Science

Volumn 350, Issue 6257, 2015, Pages 211-217

  Wheeler, Douglas B ^a,b,c,h   Zoncu, Roberto ^d   Root, David E ^c   Sabatini, David M ^c,e,f,g   Sawyers, Charles L ^a,g  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^h DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN RAB35; RAB PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; LAMP2 PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; RAB35 PROTEIN, HUMAN; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

APOPTOSIS; ENZYME ACTIVITY; GENE EXPRESSION; IDENTIFICATION METHOD; IMMUNE SYSTEM; LIGAND; MEMBRANE; MOLECULAR ANALYSIS; MUTATION; PROTEIN; RNA; TUMOR;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; ENZYME PHOSPHORYLATION; FEMALE; GENE MUTATION; GENETIC SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STABLE EXPRESSION; UPREGULATION; GENE DELETION; GENETICS; METABOLISM; MUTATION; NEOPLASM; PATHOLOGY; PHOSPHORYLATION; PROTEIN TRANSPORT; RNA INTERFERENCE; TUMOR CELL LINE;

ALLELES; CELL LINE, TUMOR; GENE DELETION; HUMANS; IMMUNOPRECIPITATION; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; MULTIPROTEIN COMPLEXES; MUTATION; NEOPLASMS; ONCOGENE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RAB GTP-BINDING PROTEINS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RNA INTERFERENCE; RNA, SMALL INTERFERING; TOR SERINE-THREONINE KINASES;

EID: 84943643169     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa4903     Document Type: Article

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