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Volumn 43, Issue 6, 2015, Pages 1099-1115

Anti-neuroinflammatory effects of uncaria sinensis in LPS-Stimulated BV2 microglia cells and focal cerebral ischemic mice

Author keywords

Focal Cerebral Ischemia; Microglia; Neuroinflammation; Uncaria sinensis

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; PLANT EXTRACT; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; UNCARIA SINENSIS EXTRACT; UNCLASSIFIED DRUG; CYTOKINE;

EID: 84943584178     PISSN: 0192415X     EISSN: 17936853     Source Type: Journal    
DOI: 10.1142/S0192415X15500639     Document Type: Article
Times cited : (26)

References (26)
  • 1
    • 34548382463 scopus 로고    scopus 로고
    • Plants traditionally used in age related brain disorders-A survey of ethnobotanical literature
    • Adams M.,F. Gmunder,M. Hamburger. Plants traditionally used in age related brain disorders-A survey of ethnobotanical literature J. Ethnopharmacol. 113 363-381 2007.
    • (2007) J. Ethnopharmacol , vol.113 , pp. 363-381
    • Adams, M.1    Gmunder, F.2    Hamburger, M.3
  • 2
    • 84905089975 scopus 로고    scopus 로고
    • Neuroprotective effect of 1-methoxyoctadecan-1-ol from uncaria sinensis on glutamate-induced hippocampal neuronal cell death
    • Ahn, S.M., H.N. Kim, Y.R. Kim, E.Y. Oh, Y.W. Choi, H.K. Shin and B.T. Choi. Neuroprotective effect of 1-methoxyoctadecan-1-ol from Uncaria sinensis on glutamate-induced hippocampal neuronal cell death. J. Ethnopharmacol. 155: 293-299, 2014.
    • (2014) J. Ethnopharmacol , vol.155 , pp. 293-299
    • Ahn, S.M.1    Kim, H.N.2    Kim, Y.R.3    Oh, E.Y.4    Choi, Y.W.5    Shin, H.K.6    Choi, B.T.7
  • 3
    • 0041784698 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
    • Brown, G.C. and A. Bal-Price. Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. Mol. Neurobiol. 27: 325-355, 2003.
    • (2003) Mol. Neurobiol , vol.27 , pp. 325-355
    • Brown, G.C.1    Bal-Price, A.2
  • 4
    • 0033650241 scopus 로고    scopus 로고
    • Vasodilator effect of extract prepared from uncariae ramulus on isolated rat aorta
    • Goto, H., I. Sakaki bara, Y. Shimada, Y. Kasahara and K. Terasawa. Vasodilator effect of extract prepared from Uncariae ramulus on isolated rat aorta. Am. J. Chin. Med. 28: 197-203, 2000.
    • (2000) Am. J. Chin. Med , vol.28 , pp. 197-203
    • Goto, H.1    Sakaki bara, I.2    Shimada, Y.3    Kasahara, Y.4    Terasawa, K.5
  • 5
    • 0033257646 scopus 로고    scopus 로고
    • Effect of uncariae ramulus et uncus on endothelium in spontaneously hypertensive rats
    • Goto, H., Y. Shimada, K. Taniga wa, N. Sekiya, T. Shintani and K. Terasawa. Effect of Uncariae ramulus et Uncus on endothelium in spontaneously hypertensive rats. Am. J. Chin. Med. 27: 339-345, 1999.
    • (1999) Am. J. Chin. Med , vol.27 , pp. 339-345
    • Goto, H.1    Shimada, Y.2    Taniga wa, K.3    Sekiya, N.4    Shintani, T.5    Terasawa, K.6
  • 6
    • 34848918865 scopus 로고    scopus 로고
    • Inhibitory effect of uncaria sinensis on human aortic smooth muscle cell migration is based on matrix metalloproteinase-9 inhibitory activity
    • Ha, K.T., K.W. Kim, S.J. Suh, C.G. Kwak, J.K. Kim and C.H. Kim. Inhibitory effect of Uncaria sinensis on human aortic smooth muscle cell migration is based on matrix metalloproteinase-9 inhibitory activity. Environ. Toxicol. Pharmacol. 24: 218-222, 2007.
    • (2007) Environ. Toxicol. Pharmacol , vol.24 , pp. 218-222
    • Ha, K.T.1    Kim, K.W.2    Suh, S.J.3    Kwak, C.G.4    Kim, J.K.5    Kim, C.H.6
  • 8
    • 84896973807 scopus 로고    scopus 로고
    • Neuroprotective effects of a novel single compound 1-methoxyoctadecan-1-ol isolated from uncaria sinensis in primary cortical neurons and a photothrombotic ischemia model
    • Jang, J.Y., Y.W. Choi, H.N. Kim, Y.R. Kim, J.W. Hong, D.W. Bae, S.J. Park, H.K. Shin and B.T. Choi. Neuroprotective effects of a novel single compound 1-methoxyoctadecan-1-ol isolated from Uncaria sinensis in primary cortical neurons and a photothrombotic ischemia model. PLoS One 9: e85322, 2 014.
    • (2014) PLoS One , vol.9 , pp. e85322
    • Jang, J.Y.1    Choi, Y.W.2    Kim, H.N.3    Kim, Y.R.4    Hong, J.W.5    Bae, D.W.6    Park, S.J.7    Shin, H.K.8    Choi, B.T.9
  • 9
    • 84869408322 scopus 로고    scopus 로고
    • Hexane extract from uncaria sinensis exhibits anti-Apoptotic properties against glutamate-induced neurotoxicity in primary cultured cortical neurons
    • Jang, J.Y., H.N. Kim, Y.R. Kim, J.W. Hong, Y.W. Choi, Y.H. Choi, H.K. Shin and B.T. Choi. Hexane extract from Uncaria sinensis exhibits anti-Apoptotic properties against glutamate-induced neurotoxicity in primary cultured cortical neurons. Int. J. Mol. Med. 30: 1465-1472, 2012.
    • (2012) Int. J. Mol. Med , vol.30 , pp. 1465-1472
    • Jang, J.Y.1    Kim, H.N.2    Kim, Y.R.3    Hong, J.W.4    Choi, Y.W.5    Choi, Y.H.6    Shin, H.K.7    Choi, B.T.8
  • 13
    • 55949104665 scopus 로고    scopus 로고
    • TNF signaling inhibition in the cns: Implications for normal brain function and neurodegenerative disease
    • McCoy, M.K. and M.G. Tansey. TNF signaling inhibition in the CNS: Implications for normal brain function and neurodegenerative disease. J. Neuroinflammation 5: 45, 2008.
    • (2008) J. Neuroinflammation , vol.5 , pp. 45
    • McCoy, M.K.1    Tansey, M.G.2
  • 14
    • 82455164145 scopus 로고    scopus 로고
    • Protective effect of hexane extracts of uncaria sinensis against photothromboti c ischemic injury in mice
    • Park, S.H., J.H. Kim, S.J. Park, S.S. Bae, Y.W. Choi, J.W. Hong, B.T. Choi and H.K. Shin. Protective effect of hexane extracts of Uncaria sinensis against photothromboti c ischemic injury in mice. J. Ethnopharmacol. 138: 774-779, 2011.
    • (2011) J. Ethnopharmacol , vol.138 , pp. 774-779
    • Park, S.H.1    Kim, J.H.2    Park, S.J.3    Bae, S.S.4    Choi, Y.W.5    Hong, J.W.6    Choi, B.T.7    Shin, H.K.8
  • 15
    • 0031438499 scopus 로고    scopus 로고
    • The role of interleukin 1 in acute neurodegeneration and stroke: Pathophysiological and therapeutic implications
    • Rothwell, N., S. Allan and S. Toulmond. The role of interleukin 1 in acute neurodegeneration and stroke: Pathophysiological and therapeutic implications. J. Clin. Invest. 100: 2648-2652, 1997.
    • (1997) J. Clin. Invest , vol.100 , pp. 2648-2652
    • Rothwell, N.1    Allan, S.2    Toulmond, S.3
  • 16
    • 53949090765 scopus 로고    scopus 로고
    • Nf-kappab signaling pathway and its therapeutic implications in human diseases
    • Sarkar, F.H., Y. Li, Z. Wang and D. Kong. NF-kappaB signaling pathway and its therapeutic implications in human diseases. Int. Rev. Immunol. 27: 293-319, 2008.
    • (2008) Int. Rev. Immunol , vol.27 , pp. 293-319
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4
  • 17
    • 0024401054 scopus 로고
    • Production of tumor necro sis factor-Alpha by microglia and astrocytes in culture
    • Sawada, M., N. Kondo, A. Suzumura and T. Marunouchi. Production of tumor necro sis factor-Alpha by microglia and astrocytes in culture. Brain Res. 491: 394-397, 1989.
    • (1989) Brain Res , vol.491 , pp. 394-397
    • Sawada, M.1    Kondo, N.2    Suzumura, A.3    Marunouchi, T.4
  • 18
    • 0032801801 scopus 로고    scopus 로고
    • Evaluation of the pr otective effects of alkaloids isolated from the hooks and stems of uncaria sinensis on glutamate-induced neuronal death in cultured cerebellar granule cells from rats
    • Shimada, Y., H. Goto, T. Itoh, I. Sakakibara, M. Kubo, H. Sasaki and K. Terasawa. Evaluation of the pr otective effects of alkaloids isolated from the hooks and stems of Uncaria sinensis on glutamate-induced neuronal death in cultured cerebellar granule cells from rats. J. Pharm. Pharmacol. 51: 715-722, 1999.
    • (1999) J. Pharm. Pharmacol , vol.51 , pp. 715-722
    • Shimada, Y.1    Goto, H.2    Itoh, T.3    Sakakibara, I.4    Kubo, M.5    Sasaki, H.6    Terasawa, K.7
  • 19
    • 0035236682 scopus 로고    scopus 로고
    • Protective effect of phenolic compounds isolated from the hooks and stems of uncaria sinensis on glutamate-induced neuronal death
    • Shimada, Y., H. Goto, T. Kogure, N. Shibahara, I. Sakakibara, H. Sasaki and K. Terasawa. Protective effect of phenolic compounds isolated from the hooks and stems of Uncaria sinensis on glutamate-induced neuronal death. Am. J. Chin. Med. 29: 173-180, 2001.
    • (2001) Am. J. Chin. Med , vol.29 , pp. 173-180
    • Shimada, Y.1    Goto, H.2    Kogure, T.3    Shibahara, N.4    Sakakibara, I.5    Sasaki, H.6    Terasawa, K.7
  • 21
    • 0033952635 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is induced in microglia during chronic cerebral ischemia in humans
    • Tomimoto, H., I. Akiguchi, H. Wakita, J.X. Lin and H. Budka. Cyclooxygenase-2 is induced in microglia during chronic cerebral ischemia in humans. Acta Neuropathol. 99: 26-30, 2000.
    • (2000) Acta Neuropathol , vol.99 , pp. 26-30
    • Tomimoto, H.1    Akiguchi, I.2    Wakita, H.3    Lin, J.X.4    Budka, H.5
  • 22
    • 33847644971 scopus 로고    scopus 로고
    • The inflammatory response in stroke
    • Wang, Q., X.N. Tang and M.A. Yenari. The inflammatory response in stroke. J. Neuroimmunol. 184: 53-68, 2007.
    • (2007) J. Neuroimmunol , vol.184 , pp. 53-68
    • Wang, Q.1    Tang, X.N.2    Yenari, M.A.3
  • 23
    • 70349636710 scopus 로고    scopus 로고
    • Inflammatory markers and poor outcome after stroke: A prospective cohort study and systematic review of interleukin-6
    • Whiteley W.,C. Jackson,S. Lewis,G. Lowe,A. Rumley,P. Sandercock,J. Wardlaw,M. Dennis,C. Su dlow. Inflammatory markers and poor outcome after stroke: A prospective cohort study and systematic review of interleukin-6 Plos Med. 6 e1000145 2009.
    • (2009) Plos Med , vol.6 , pp. e1000145
    • Whiteley, W.1    Jackson, C.2    Lewis, S.3    Lowe, G.4    Rumley, A.5    Sandercock, P.6    Wardlaw, J.7    Dennis, M.8    Sudlow, C.9
  • 24
    • 7044285884 scopus 로고    scopus 로고
    • Effects of choto-san and hooks and stems of uncaria sinensis on antioxidant enzyme ac tivities in the gerbil brain after transient forebrain ischemia
    • Yokoyama, K., Y. Shimada, E. Hori, T. Nakagawa, S. Takagi, N. Sekiya, K. Kouta, H. Nishijo, T. Yokozawa and K. Terasawa. Effects of Choto-san and hooks and stems of Uncaria sinensis on antioxidant enzyme ac tivities in the gerbil brain after transient forebrain ischemia. J. Ethnopharmacol. 95: 335-343, 2004a .
    • (2004) J. Ethnopharmacol , vol.95 , pp. 335-343
    • Yokoyama, K.1    Shimada, Y.2    Hori, E.3    Nakagawa, T.4    Takagi, S.5    Sekiya, N.6    Kouta, K.7    Nishijo, H.8    Yokozawa, T.9    Terasawa, K.10
  • 25
    • 4744368039 scopus 로고    scopus 로고
    • Protective effects of choto-san and hooks and stems of uncaria sinensis against delayed neuronal death after transient forebrain ischemia in gerbil
    • Yokoyama, K., Y. Shimada, E. Hori, N. Sekiya, H. Goto, I. Sakakibara, H. Nishijo and K. Terasawa. Protective effects of Choto-san and hooks and stems of Uncaria sinensis against delayed neuronal death after transient forebrain ischemia in gerbil. Phytomedicine 11: 478-489, 2004 b.
    • (2004) Phytomedicine , vol.11 , pp. 478-489
    • Yokoyama, K.1    Shimada, Y.2    Hori, E.3    Sekiya, N.4    Goto, H.5    Sakakibara, I.6    Nishijo, H.7    Terasawa, K.8
  • 26
    • 10344229430 scopus 로고    scopus 로고
    • Post-ischemic inflammation: Molecular mechanisms and therapeutic implications
    • Zheng, Z. and M. A. Yenari. Post-ischemic inflammation: Molecular mechanisms and therapeutic implications. Neurol. Res. 26: 884-892, 2004.
    • (2004) Neurol. Res , vol.26 , pp. 884-892
    • Zheng, Z.1    Yenari, M.A.2


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