-
1
-
-
2042546096
-
Balancing acts: molecular control of mammalian iron metabolism
-
Hentze M.W., Muckenthaler M.U., Andrews N.C. Balancing acts: molecular control of mammalian iron metabolism. Cell 2004, 117:285-297.
-
(2004)
Cell
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
4
-
-
51849108672
-
-
World Health Organization, Geneva, B. de Benoist, E. McLean, I. Egli, M. Cogswell (Eds.)
-
Worldwide Prevalence of Anaemia 1993-2005: WHO Global Database on Anaemia 2008, World Health Organization, Geneva. B. de Benoist, E. McLean, I. Egli, M. Cogswell (Eds.).
-
(2008)
Worldwide Prevalence of Anaemia 1993-2005: WHO Global Database on Anaemia
-
-
-
5
-
-
84891373826
-
Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation
-
Crespo A.C., Silva B., Marques L., Marcelino E., Maruta C., Costa S., Timoteo A., Vilares A., Couto F.S., Faustino P., Correia A.P., Verdelho A., Porto G., Guerreiro M., Herrero A., Costa C., de Mendonca A., Costa L., Martins M. Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation. Neurobiol Aging 2014, 35:777-785.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 777-785
-
-
Crespo, A.C.1
Silva, B.2
Marques, L.3
Marcelino, E.4
Maruta, C.5
Costa, S.6
Timoteo, A.7
Vilares, A.8
Couto, F.S.9
Faustino, P.10
Correia, A.P.11
Verdelho, A.12
Porto, G.13
Guerreiro, M.14
Herrero, A.15
Costa, C.16
de Mendonca, A.17
Costa, L.18
Martins, M.19
-
6
-
-
84927941788
-
Chronic iron deficiency as an emerging risk factor for osteoporosis: a hypothesis
-
Toxqui L., Vaquero M.P. Chronic iron deficiency as an emerging risk factor for osteoporosis: a hypothesis. Nutrients 2015, 7:2324-2344.
-
(2015)
Nutrients
, vol.7
, pp. 2324-2344
-
-
Toxqui, L.1
Vaquero, M.P.2
-
8
-
-
84896477943
-
Influence of diet, menstruation and genetic factors on iron status: a cross-sectional study in Spanish women of childbearing age
-
Blanco-Rojo R., Toxqui L., Lopez-Parra A.M., Baeza-Richer C., Perez-Granados A.M., Arroyo-Pardo E., Vaquero M.P. Influence of diet, menstruation and genetic factors on iron status: a cross-sectional study in Spanish women of childbearing age. Int. J. Mol. Sci. 2014, 15:4077-4087.
-
(2014)
Int. J. Mol. Sci.
, vol.15
, pp. 4077-4087
-
-
Blanco-Rojo, R.1
Toxqui, L.2
Lopez-Parra, A.M.3
Baeza-Richer, C.4
Perez-Granados, A.M.5
Arroyo-Pardo, E.6
Vaquero, M.P.7
-
9
-
-
9344224529
-
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
-
Feder J.N., Gnirke A., Thomas W., Tsuchihashi Z., Ruddy D.A., Basava A., Dormishian F., Domingo R., Ellis M.C., Fullan A., Hinton L.M., Jones N.L., Kimmel B.E., Kronmal G.S., Lauer P., Lee V.K., Loeb D.B., Mapa F.A., McClelland E., Meyer N.C., Mintier G.A., Moeller N., Moore T., Morikang E., Prass C.E., Quintana L., Starnes S.M., Schatzman R.C., Brunke K.J., Drayna D.T., Risch N.J., Bacon B.R., Wolff R.K. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat. Genet. 1996, 13:399-408.
-
(1996)
Nat. Genet.
, vol.13
, pp. 399-408
-
-
Feder, J.N.1
Gnirke, A.2
Thomas, W.3
Tsuchihashi, Z.4
Ruddy, D.A.5
Basava, A.6
Dormishian, F.7
Domingo, R.8
Ellis, M.C.9
Fullan, A.10
Hinton, L.M.11
Jones, N.L.12
Kimmel, B.E.13
Kronmal, G.S.14
Lauer, P.15
Lee, V.K.16
Loeb, D.B.17
Mapa, F.A.18
McClelland, E.19
Meyer, N.C.20
Mintier, G.A.21
Moeller, N.22
Moore, T.23
Morikang, E.24
Prass, C.E.25
Quintana, L.26
Starnes, S.M.27
Schatzman, R.C.28
Brunke, K.J.29
Drayna, D.T.30
Risch, N.J.31
Bacon, B.R.32
Wolff, R.K.33
more..
-
10
-
-
20244386421
-
HJV gene mutations in European patients with juvenile hemochromatosis
-
Gehrke S.G., Pietrangelo A., Kascak M., Braner A., Eisold M., Kulaksiz H., Herrmann T., Hebling U., Bents K., Gugler R., Stremmel W. HJV gene mutations in European patients with juvenile hemochromatosis. Clin. Genet. 2005, 67:425-428.
-
(2005)
Clin. Genet.
, vol.67
, pp. 425-428
-
-
Gehrke, S.G.1
Pietrangelo, A.2
Kascak, M.3
Braner, A.4
Eisold, M.5
Kulaksiz, H.6
Herrmann, T.7
Hebling, U.8
Bents, K.9
Gugler, R.10
Stremmel, W.11
-
11
-
-
70349309740
-
Iron-refractory iron deficiency anemia
-
Finberg K.E. Iron-refractory iron deficiency anemia. Semin. Hematol. 2009, 46:378-386.
-
(2009)
Semin. Hematol.
, vol.46
, pp. 378-386
-
-
Finberg, K.E.1
-
12
-
-
0033966370
-
Genetic influences on F cells and other hematologic variables: a twin heritability study
-
Garner C., Tatu T., Reittie J.E., Littlewood T., Darley J., Cervino S., Farrall M., Kelly P., Spector T.D., Thein S.L. Genetic influences on F cells and other hematologic variables: a twin heritability study. Blood 2000, 95:342-346.
-
(2000)
Blood
, vol.95
, pp. 342-346
-
-
Garner, C.1
Tatu, T.2
Reittie, J.E.3
Littlewood, T.4
Darley, J.5
Cervino, S.6
Farrall, M.7
Kelly, P.8
Spector, T.D.9
Thein, S.L.10
-
13
-
-
0346733120
-
Genetic determinants of iron metabolism plasma phenotypes and their relationship with risk of thrombosis
-
Souto J.C., Remacha A., Buil A., Almasy L., Blangero J., Fontcuberta J. Genetic determinants of iron metabolism plasma phenotypes and their relationship with risk of thrombosis. Haematologica 2003, 88:1436-1438.
-
(2003)
Haematologica
, vol.88
, pp. 1436-1438
-
-
Souto, J.C.1
Remacha, A.2
Buil, A.3
Almasy, L.4
Blangero, J.5
Fontcuberta, J.6
-
14
-
-
33748501230
-
Heritability of serum iron, ferritin and transferrin saturation in a genetically isolated population, the Erasmus Rucphen Family (ERF) Study
-
Njajou O.T., Alizadeh B.Z., Aulchenko Y., Zillikens M.C., Pols H.A., Oostra B.A., Swinkels D.W., van Duijn C.M. Heritability of serum iron, ferritin and transferrin saturation in a genetically isolated population, the Erasmus Rucphen Family (ERF) Study. Hum. Hered. 2006, 61:222-228.
-
(2006)
Hum. Hered.
, vol.61
, pp. 222-228
-
-
Njajou, O.T.1
Alizadeh, B.Z.2
Aulchenko, Y.3
Zillikens, M.C.4
Pols, H.A.5
Oostra, B.A.6
Swinkels, D.W.7
van Duijn, C.M.8
-
15
-
-
58049202750
-
Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels
-
Benyamin B., McRae A.F., Zhu G., Gordon S., Henders A.K., Palotie A., Peltonen L., Martin N.G., Montgomery G.W., Whitfield J.B., Visscher P.M. Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. Am. J. Hum. Genet. 2009, 84:60-65.
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 60-65
-
-
Benyamin, B.1
McRae, A.F.2
Zhu, G.3
Gordon, S.4
Henders, A.K.5
Palotie, A.6
Peltonen, L.7
Martin, N.G.8
Montgomery, G.W.9
Whitfield, J.B.10
Visscher, P.M.11
-
16
-
-
84923272209
-
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis
-
Benyamin B., Esko T., Ried J.S., Radhakrishnan A., Vermeulen S.H., Traglia M., Gogele M., Anderson D., Broer L., Podmore C., Luan J., Kutalik Z., Sanna S., van der Meer P., Tanaka T., Wang F., Westra H.J., Franke L., Mihailov E., Milani L., Haldin J., Winkelmann J., Meitinger T., Thiery J., Peters A., Waldenberger M., Rendon A., Jolley J., Sambrook J., Kiemeney L.A., Sweep F.C., Sala C.F., Schwienbacher C., Pichler I., Hui J., Demirkan A., Isaacs A., Amin N., Steri M., Waeber G., Verweij N., Powell J.E., Nyholt D.R., Heath A.C., Madden P.A., Visscher P.M., Wright M.J., Montgomery G.W., Martin N.G., Hernandez D., Bandinelli S., van der Harst P., Uda M., Vollenweider P., Scott R.A., Langenberg C., Wareham N.J., van Duijn C., Beilby J., Pramstaller P.P., Hicks A.A., Ouwehand W.H., Oexle K., Gieger C., Metspalu A., Camaschella C., Toniolo D., Swinkels D.W., Whitfield J.B. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat. Commun. 2014, 5:4926.
-
(2014)
Nat. Commun.
, vol.5
, pp. 4926
-
-
Benyamin, B.1
Esko, T.2
Ried, J.S.3
Radhakrishnan, A.4
Vermeulen, S.H.5
Traglia, M.6
Gogele, M.7
Anderson, D.8
Broer, L.9
Podmore, C.10
Luan, J.11
Kutalik, Z.12
Sanna, S.13
van der Meer, P.14
Tanaka, T.15
Wang, F.16
Westra, H.J.17
Franke, L.18
Mihailov, E.19
Milani, L.20
Haldin, J.21
Winkelmann, J.22
Meitinger, T.23
Thiery, J.24
Peters, A.25
Waldenberger, M.26
Rendon, A.27
Jolley, J.28
Sambrook, J.29
Kiemeney, L.A.30
Sweep, F.C.31
Sala, C.F.32
Schwienbacher, C.33
Pichler, I.34
Hui, J.35
Demirkan, A.36
Isaacs, A.37
Amin, N.38
Steri, M.39
Waeber, G.40
Verweij, N.41
Powell, J.E.42
Nyholt, D.R.43
Heath, A.C.44
Madden, P.A.45
Visscher, P.M.46
Wright, M.J.47
Montgomery, G.W.48
Martin, N.G.49
Hernandez, D.50
Bandinelli, S.51
van der Harst, P.52
Uda, M.53
Vollenweider, P.54
Scott, R.A.55
Langenberg, C.56
Wareham, N.J.57
van Duijn, C.58
Beilby, J.59
Pramstaller, P.P.60
Hicks, A.A.61
Ouwehand, W.H.62
Oexle, K.63
Gieger, C.64
Metspalu, A.65
Camaschella, C.66
Toniolo, D.67
Swinkels, D.W.68
Whitfield, J.B.69
more..
-
17
-
-
70350644759
-
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
-
Soranzo N., Spector T.D., Mangino M., Kuhnel B., Rendon A., Teumer A., Willenborg C., Wright B., Chen L., Li M., Salo P., Voight B.F., Burns P., Laskowski R.A., Xue Y., Menzel S., Altshuler D., Bradley J.R., Bumpstead S., Burnett M.S., Devaney J., Doring A., Elosua R., Epstein S.E., Erber W., Falchi M., Garner S.F., Ghori M.J., Goodall A.H., Gwilliam R., Hakonarson H.H., Hall A.S., Hammond N., Hengstenberg C., Illig T., Konig I.R., Knouff C.W., McPherson R., Melander O., Mooser V., Nauck M., Nieminen M.S., O'Donnell C.J., Peltonen L., Potter S.C., Prokisch H., Rader D.J., Rice C.M., Roberts R., Salomaa V., Sambrook J., Schreiber S., Schunkert H., Schwartz S.M., Serbanovic-Canic J., Sinisalo J., Siscovick D.S., Stark K., Surakka I., Stephens J., Thompson J.R., Volker U., Volzke H., Watkins N.A., Wells G.A., Wichmann H.E., Van Heel D.A., Tyler-Smith C., Thein S.L., Kathiresan S., Perola M., Reilly M.P., Stewart A.F., Erdmann J., Samani N.J., Meisinger C., Greinacher A., Deloukas P., Ouwehand W.H., Gieger C. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat. Genet. 2009, 41:1182-1190.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1182-1190
-
-
Soranzo, N.1
Spector, T.D.2
Mangino, M.3
Kuhnel, B.4
Rendon, A.5
Teumer, A.6
Willenborg, C.7
Wright, B.8
Chen, L.9
Li, M.10
Salo, P.11
Voight, B.F.12
Burns, P.13
Laskowski, R.A.14
Xue, Y.15
Menzel, S.16
Altshuler, D.17
Bradley, J.R.18
Bumpstead, S.19
Burnett, M.S.20
Devaney, J.21
Doring, A.22
Elosua, R.23
Epstein, S.E.24
Erber, W.25
Falchi, M.26
Garner, S.F.27
Ghori, M.J.28
Goodall, A.H.29
Gwilliam, R.30
Hakonarson, H.H.31
Hall, A.S.32
Hammond, N.33
Hengstenberg, C.34
Illig, T.35
Konig, I.R.36
Knouff, C.W.37
McPherson, R.38
Melander, O.39
Mooser, V.40
Nauck, M.41
Nieminen, M.S.42
O'Donnell, C.J.43
Peltonen, L.44
Potter, S.C.45
Prokisch, H.46
Rader, D.J.47
Rice, C.M.48
Roberts, R.49
Salomaa, V.50
Sambrook, J.51
Schreiber, S.52
Schunkert, H.53
Schwartz, S.M.54
Serbanovic-Canic, J.55
Sinisalo, J.56
Siscovick, D.S.57
Stark, K.58
Surakka, I.59
Stephens, J.60
Thompson, J.R.61
Volker, U.62
Volzke, H.63
Watkins, N.A.64
Wells, G.A.65
Wichmann, H.E.66
Van Heel, D.A.67
Tyler-Smith, C.68
Thein, S.L.69
Kathiresan, S.70
Perola, M.71
Reilly, M.P.72
Stewart, A.F.73
Erdmann, J.74
Samani, N.J.75
Meisinger, C.76
Greinacher, A.77
Deloukas, P.78
Ouwehand, W.H.79
Gieger, C.80
more..
-
18
-
-
80053487857
-
Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women
-
Blanco-Rojo R., Baeza-Richer C., Lopez-Parra A.M., Perez-Granados A.M., Brichs A., Bertoncini S., Buil A., Arroyo-Pardo E., Soria J.M., Vaquero M.P. Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women. Nutr. Metab. (Lond.) 2011, 8:69.
-
(2011)
Nutr. Metab. (Lond.)
, vol.8
, pp. 69
-
-
Blanco-Rojo, R.1
Baeza-Richer, C.2
Lopez-Parra, A.M.3
Perez-Granados, A.M.4
Brichs, A.5
Bertoncini, S.6
Buil, A.7
Arroyo-Pardo, E.8
Soria, J.M.9
Vaquero, M.P.10
-
19
-
-
84938209461
-
Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload
-
McLaren C.E., Emond M.J., Subramaniam V.N., Phatak P.D., Barton J.C., Adams P.C., Goh J.B., McDonald C.J., Powell L.W., Gurrin L.C., Allen K.J., Nickerson D.A., Louie T., Ramm G.A., Anderson G.J., McLaren G.D. Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology 2015, 10.1002/hep.27711.
-
(2015)
Hepatology
-
-
McLaren, C.E.1
Emond, M.J.2
Subramaniam, V.N.3
Phatak, P.D.4
Barton, J.C.5
Adams, P.C.6
Goh, J.B.7
McDonald, C.J.8
Powell, L.W.9
Gurrin, L.C.10
Allen, K.J.11
Nickerson, D.A.12
Louie, T.13
Ramm, G.A.14
Anderson, G.J.15
McLaren, G.D.16
-
20
-
-
84859243904
-
TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia
-
An P., Wu Q., Wang H., Guan Y., Mu M., Liao Y., Zhou D., Song P., Wang C., Meng L., Man Q., Li L., Zhang J., Wang F. TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia. Hum. Mol. Genet. 2012, 21:2124-2131.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 2124-2131
-
-
An, P.1
Wu, Q.2
Wang, H.3
Guan, Y.4
Mu, M.5
Liao, Y.6
Zhou, D.7
Song, P.8
Wang, C.9
Meng, L.10
Man, Q.11
Li, L.12
Zhang, J.13
Wang, F.14
-
21
-
-
84873674954
-
Identification of a novel quantitative trait nucleotype related to iron status in a calcium channel gene
-
Baeza-Richer C., Blanco-Rojo R., Lopez-Parra A.M., Brichs A., Bertoncini S., Perez-Granados A.M., Buil A., Soria J.M., Arroyo-Pardo E., Vaquero M.P. Identification of a novel quantitative trait nucleotype related to iron status in a calcium channel gene. Dis. Markers 2013, 34:121-129.
-
(2013)
Dis. Markers
, vol.34
, pp. 121-129
-
-
Baeza-Richer, C.1
Blanco-Rojo, R.2
Lopez-Parra, A.M.3
Brichs, A.4
Bertoncini, S.5
Perez-Granados, A.M.6
Buil, A.7
Soria, J.M.8
Arroyo-Pardo, E.9
Vaquero, M.P.10
-
22
-
-
72649088708
-
Polymorphisms and mutations of human TMPRSS6 in iron deficiency anemia
-
Beutler E., Van Geet C., te Loo D.M., Gelbart T., Crain K., Truksa J., Lee P.L. Polymorphisms and mutations of human TMPRSS6 in iron deficiency anemia. Blood Cells Mol. Dis. 2009, 44:16-21.
-
(2009)
Blood Cells Mol. Dis.
, vol.44
, pp. 16-21
-
-
Beutler, E.1
Van Geet, C.2
te Loo, D.M.3
Gelbart, T.4
Crain, K.5
Truksa, J.6
Lee, P.L.7
-
23
-
-
33748804424
-
A tutorial on statistical methods for population association studies
-
Balding D.J. A tutorial on statistical methods for population association studies. Nat. Rev. Genet. 2006, 7:781-791.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 781-791
-
-
Balding, D.J.1
-
24
-
-
37349042287
-
Studies of association in complex diseases: statistical problems related to the analysis of genetic polymorphisms
-
Salas A., Carracedo A. Studies of association in complex diseases: statistical problems related to the analysis of genetic polymorphisms. Rev. Clin. Esp. 2007, 207:563-565.
-
(2007)
Rev. Clin. Esp.
, vol.207
, pp. 563-565
-
-
Salas, A.1
Carracedo, A.2
-
25
-
-
34249997024
-
Replicating genotype-phenotype associations
-
Chanock S.J., Manolio T., Boehnke M., Boerwinkle E., Hunter D.J., Thomas G., Hirschhorn J.N., Abecasis G., Altshuler D., Bailey-Wilson J.E., Brooks L.D., Cardon L.R., Daly M., Donnelly P., Fraumeni J.F., Freimer N.B., Gerhard D.S., Gunter C., Guttmacher A.E., Guyer M.S., Harris E.L., Hoh J., Hoover R., Kong C.A., Merikangas K.R., Morton C.C., Palmer L.J., Phimister E.G., Rice J.P., Roberts J., Rotimi C., Tucker M.A., Vogan K.J., Wacholder S., Wijsman E.M., Winn D.M., Collins F.S. Replicating genotype-phenotype associations. Nature 2007, 447:655-660.
-
(2007)
Nature
, vol.447
, pp. 655-660
-
-
Chanock, S.J.1
Manolio, T.2
Boehnke, M.3
Boerwinkle, E.4
Hunter, D.J.5
Thomas, G.6
Hirschhorn, J.N.7
Abecasis, G.8
Altshuler, D.9
Bailey-Wilson, J.E.10
Brooks, L.D.11
Cardon, L.R.12
Daly, M.13
Donnelly, P.14
Fraumeni, J.F.15
Freimer, N.B.16
Gerhard, D.S.17
Gunter, C.18
Guttmacher, A.E.19
Guyer, M.S.20
Harris, E.L.21
Hoh, J.22
Hoover, R.23
Kong, C.A.24
Merikangas, K.R.25
Morton, C.C.26
Palmer, L.J.27
Phimister, E.G.28
Rice, J.P.29
Roberts, J.30
Rotimi, C.31
Tucker, M.A.32
Vogan, K.J.33
Wacholder, S.34
Wijsman, E.M.35
Winn, D.M.36
Collins, F.S.37
more..
-
26
-
-
0142029070
-
Data mining: qualitative analysis with health informatics data
-
Castellani B., Castellani J. Data mining: qualitative analysis with health informatics data. Qual. Health Res. 2003, 13:1005-1018.
-
(2003)
Qual. Health Res.
, vol.13
, pp. 1005-1018
-
-
Castellani, B.1
Castellani, J.2
-
27
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Dunham I. An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489:57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Dunham, I.1
-
28
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory DNA
-
Maurano M.T., Humbert R., Rynes E., Thurman R.E., Haugen E., Wang H., Reynolds A.P., Sandstrom R., Qu H., Brody J., Shafer A., Neri F., Lee K., Kutyavin T., Stehling-Sun S., Johnson A.K., Canfield T.K., Giste E., Diegel M., Bates D., Hansen R.S., Neph S., Sabo P.J., Heimfeld S., Raubitschek A., Ziegler S., Cotsapas C., Sotoodehnia N., Glass I., Sunyaev S.R., Kaul R., Stamatoyannopoulos J.A. Systematic localization of common disease-associated variation in regulatory DNA. Science 2012, 337:1190-1195.
-
(2012)
Science
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
Humbert, R.2
Rynes, E.3
Thurman, R.E.4
Haugen, E.5
Wang, H.6
Reynolds, A.P.7
Sandstrom, R.8
Qu, H.9
Brody, J.10
Shafer, A.11
Neri, F.12
Lee, K.13
Kutyavin, T.14
Stehling-Sun, S.15
Johnson, A.K.16
Canfield, T.K.17
Giste, E.18
Diegel, M.19
Bates, D.20
Hansen, R.S.21
Neph, S.22
Sabo, P.J.23
Heimfeld, S.24
Raubitschek, A.25
Ziegler, S.26
Cotsapas, C.27
Sotoodehnia, N.28
Glass, I.29
Sunyaev, S.R.30
Kaul, R.31
Stamatoyannopoulos, J.A.32
more..
-
29
-
-
34848884233
-
Mechanisms and significance of cell volume regulation
-
Lang F. Mechanisms and significance of cell volume regulation. J. Am. Coll. Nutr. 2007, 26:613S-623S.
-
(2007)
J. Am. Coll. Nutr.
, vol.26
, pp. 613S-623S
-
-
Lang, F.1
-
30
-
-
34548767817
-
Voltage-gated calcium channels provide an alternate route for iron uptake in neuronal cell cultures
-
Gaasch J.A., Geldenhuys W.J., Lockman P.R., Allen D.D., Van der Schyf C.J. Voltage-gated calcium channels provide an alternate route for iron uptake in neuronal cell cultures. Neurochem. Res. 2007, 32:1686-1693.
-
(2007)
Neurochem. Res.
, vol.32
, pp. 1686-1693
-
-
Gaasch, J.A.1
Geldenhuys, W.J.2
Lockman, P.R.3
Allen, D.D.4
Van der Schyf, C.J.5
-
31
-
-
84869795033
-
Calcium channels and iron uptake into the heart
-
Chattipakorn N., Kumfu S., Fucharoen S., Chattipakorn S. Calcium channels and iron uptake into the heart. World J. Cardiol. 2011, 3:215-218.
-
(2011)
World J. Cardiol.
, vol.3
, pp. 215-218
-
-
Chattipakorn, N.1
Kumfu, S.2
Fucharoen, S.3
Chattipakorn, S.4
-
32
-
-
79952164569
-
A novel SNaPshot assay to detect genetic mutations related to iron metabolism
-
Bertoncini S., Blanco-Rojo R., Baeza C., Arroyo-Pardo E., Vaquero M.P., Lopez-Parra A.M. A novel SNaPshot assay to detect genetic mutations related to iron metabolism. Genet. Test. Mol. Biomarkers 2013, 15:173-179.
-
(2013)
Genet. Test. Mol. Biomarkers
, vol.15
, pp. 173-179
-
-
Bertoncini, S.1
Blanco-Rojo, R.2
Baeza, C.3
Arroyo-Pardo, E.4
Vaquero, M.P.5
Lopez-Parra, A.M.6
-
33
-
-
27644439141
-
Efficiency and power in genetic association studies
-
de Bakker P.I., Yelensky R., Pe'er I., Gabriel S.B., Daly M.J., Altshuler D. Efficiency and power in genetic association studies. Nat. Genet. 2005, 37:1217-1223.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1217-1223
-
-
de Bakker, P.I.1
Yelensky, R.2
Pe'er, I.3
Gabriel, S.B.4
Daly, M.J.5
Altshuler, D.6
-
34
-
-
13444269543
-
Haploview: analysis and visualization of LD and haplotype maps
-
Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
35
-
-
28944435358
-
Genomewide linkage analysis of soluble transferrin receptor plasma levels
-
Remacha A.F., Souto J.C., Soria J.M., Buil A., Sarda M.P., Lathrop M., Blangero J., Almasy L., Fontcuberta J. Genomewide linkage analysis of soluble transferrin receptor plasma levels. Ann. Hematol. 2006, 85:25-28.
-
(2006)
Ann. Hematol.
, vol.85
, pp. 25-28
-
-
Remacha, A.F.1
Souto, J.C.2
Soria, J.M.3
Buil, A.4
Sarda, M.P.5
Lathrop, M.6
Blangero, J.7
Almasy, L.8
Fontcuberta, J.9
-
36
-
-
0003485198
-
-
Chapman & Hall, London, D. Collet (Ed.)
-
Modelling Binary Data 2003, Chapman & Hall, London. D. Collet (Ed.).
-
(2003)
Modelling Binary Data
-
-
-
37
-
-
79952164569
-
A novel SNaPshot assay to detect genetic mutations related to iron metabolism
-
Bertoncini S., Blanco-Rojo R., Baeza C., Arroyo-Pardo E., Vaquero M.P., Lopez-Parra A.M. A novel SNaPshot assay to detect genetic mutations related to iron metabolism. Genet. Test. Mol. Biomarkers 2011, 15:173-179.
-
(2011)
Genet. Test. Mol. Biomarkers
, vol.15
, pp. 173-179
-
-
Bertoncini, S.1
Blanco-Rojo, R.2
Baeza, C.3
Arroyo-Pardo, E.4
Vaquero, M.P.5
Lopez-Parra, A.M.6
-
38
-
-
70350646902
-
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
-
Ganesh S.K., Zakai N.A., van Rooij F.J., Soranzo N., Smith A.V., Nalls M.A., Chen M.H., Kottgen A., Glazer N.L., Dehghan A., Kuhnel B., Aspelund T., Yang Q., Tanaka T., Jaffe A., Bis J.C., Verwoert G.C., Teumer A., Fox C.S., Guralnik J.M., Ehret G.B., Rice K., Felix J.F., Rendon A., Eiriksdottir G., Levy D., Patel K.V., Boerwinkle E., Rotter J.I., Hofman A., Sambrook J.G., Hernandez D.G., Zheng G., Bandinelli S., Singleton A.B., Coresh J., Lumley T., Uitterlinden A.G., Vangils J.M., Launer L.J., Cupples L.A., Oostra B.A., Zwaginga J.J., Ouwehand W.H., Thein S.L., Meisinger C., Deloukas P., Nauck M., Spector T.D., Gieger C., Gudnason V., van Duijn C.M., Psaty B.M., Ferrucci L., Chakravarti A., Greinacher A., O'Donnell C.J., Witteman J.C., Furth S., Cushman M., Harris T.B., Lin J.P. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat. Genet. 2009, 41:1191-1198.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1191-1198
-
-
Ganesh, S.K.1
Zakai, N.A.2
van Rooij, F.J.3
Soranzo, N.4
Smith, A.V.5
Nalls, M.A.6
Chen, M.H.7
Kottgen, A.8
Glazer, N.L.9
Dehghan, A.10
Kuhnel, B.11
Aspelund, T.12
Yang, Q.13
Tanaka, T.14
Jaffe, A.15
Bis, J.C.16
Verwoert, G.C.17
Teumer, A.18
Fox, C.S.19
Guralnik, J.M.20
Ehret, G.B.21
Rice, K.22
Felix, J.F.23
Rendon, A.24
Eiriksdottir, G.25
Levy, D.26
Patel, K.V.27
Boerwinkle, E.28
Rotter, J.I.29
Hofman, A.30
Sambrook, J.G.31
Hernandez, D.G.32
Zheng, G.33
Bandinelli, S.34
Singleton, A.B.35
Coresh, J.36
Lumley, T.37
Uitterlinden, A.G.38
Vangils, J.M.39
Launer, L.J.40
Cupples, L.A.41
Oostra, B.A.42
Zwaginga, J.J.43
Ouwehand, W.H.44
Thein, S.L.45
Meisinger, C.46
Deloukas, P.47
Nauck, M.48
Spector, T.D.49
Gieger, C.50
Gudnason, V.51
van Duijn, C.M.52
Psaty, B.M.53
Ferrucci, L.54
Chakravarti, A.55
Greinacher, A.56
O'Donnell, C.J.57
Witteman, J.C.58
Furth, S.59
Cushman, M.60
Harris, T.B.61
Lin, J.P.62
more..
-
39
-
-
70350638919
-
Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels
-
Chambers J.C., Zhang W., Li Y., Sehmi J., Wass M.N., Zabaneh D., Hoggart C., Bayele H., McCarthy M.I., Peltonen L., Freimer N.B., Srai S.K., Maxwell P.H., Sternberg M.J., Ruokonen A., Abecasis G., Jarvelin M.R., Scott J., Elliott P., Kooner J.S. Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nat. Genet. 2009, 41:1170-1172.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1170-1172
-
-
Chambers, J.C.1
Zhang, W.2
Li, Y.3
Sehmi, J.4
Wass, M.N.5
Zabaneh, D.6
Hoggart, C.7
Bayele, H.8
McCarthy, M.I.9
Peltonen, L.10
Freimer, N.B.11
Srai, S.K.12
Maxwell, P.H.13
Sternberg, M.J.14
Ruokonen, A.15
Abecasis, G.16
Jarvelin, M.R.17
Scott, J.18
Elliott, P.19
Kooner, J.S.20
more..
-
40
-
-
70350628958
-
Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
-
Benyamin B., Ferreira M.A., Willemsen G., Gordon S., Middelberg R.P., McEvoy B.P., Hottenga J.J., Henders A.K., Campbell M.J., Wallace L., Frazer I.H., Heath A.C., de Geus E.J., Nyholt D.R., Visscher P.M., Penninx B.W., Boomsma D.I., Martin N.G., Montgomery G.W., Whitfield J.B. Common variants in TMPRSS6 are associated with iron status and erythrocyte volume. Nat. Genet. 2009, 41:1173-1175.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1173-1175
-
-
Benyamin, B.1
Ferreira, M.A.2
Willemsen, G.3
Gordon, S.4
Middelberg, R.P.5
McEvoy, B.P.6
Hottenga, J.J.7
Henders, A.K.8
Campbell, M.J.9
Wallace, L.10
Frazer, I.H.11
Heath, A.C.12
de Geus, E.J.13
Nyholt, D.R.14
Visscher, P.M.15
Penninx, B.W.16
Boomsma, D.I.17
Martin, N.G.18
Montgomery, G.W.19
Whitfield, J.B.20
more..
-
41
-
-
77958522275
-
A genome-wide association study of red blood cell traits using the electronic medical record
-
Kullo I.J., Ding K., Jouni H., Smith C.Y., Chute C.G. A genome-wide association study of red blood cell traits using the electronic medical record. PLoS One 2010, 5.
-
(2010)
PLoS One
, vol.5
-
-
Kullo, I.J.1
Ding, K.2
Jouni, H.3
Smith, C.Y.4
Chute, C.G.5
-
42
-
-
79953756857
-
Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans
-
Lo K.S., Wilson J.G., Lange L.A., Folsom A.R., Galarneau G., Ganesh S.K., Grant S.F., Keating B.J., McCarroll S.A., Mohler E.R., O'Donnell C.J., Palmas W., Tang W., Tracy R.P., Reiner A.P., Lettre G. Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans. Hum. Genet. 2010, 129:307-317.
-
(2010)
Hum. Genet.
, vol.129
, pp. 307-317
-
-
Lo, K.S.1
Wilson, J.G.2
Lange, L.A.3
Folsom, A.R.4
Galarneau, G.5
Ganesh, S.K.6
Grant, S.F.7
Keating, B.J.8
McCarroll, S.A.9
Mohler, E.R.10
O'Donnell, C.J.11
Palmas, W.12
Tang, W.13
Tracy, R.P.14
Reiner, A.P.15
Lettre, G.16
-
43
-
-
79551586854
-
Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels
-
Oexle K., Ried J.S., Hicks A.A., Tanaka T., Hayward C., Bruegel M., Gogele M., Lichtner P., Muller-Myhsok B., Doring A., Illig T., Schwienbacher C., Minelli C., Pichler I., Fiedler G.M., Thiery J., Rudan I., Wright A.F., Campbell H., Ferrucci L., Bandinelli S., Pramstaller P.P., Wichmann H.E., Gieger C., Winkelmann J., Meitinger T. Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels. Hum. Mol. Genet. 2011, 20:1042-1047.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1042-1047
-
-
Oexle, K.1
Ried, J.S.2
Hicks, A.A.3
Tanaka, T.4
Hayward, C.5
Bruegel, M.6
Gogele, M.7
Lichtner, P.8
Muller-Myhsok, B.9
Doring, A.10
Illig, T.11
Schwienbacher, C.12
Minelli, C.13
Pichler, I.14
Fiedler, G.M.15
Thiery, J.16
Rudan, I.17
Wright, A.F.18
Campbell, H.19
Ferrucci, L.20
Bandinelli, S.21
Pramstaller, P.P.22
Wichmann, H.E.23
Gieger, C.24
Winkelmann, J.25
Meitinger, T.26
more..
-
44
-
-
79952016793
-
Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels
-
Pichler I., Minelli C., Sanna S., Tanaka T., Schwienbacher C., Naitza S., Porcu E., Pattaro C., Busonero F., Zanon A., Maschio A., Melville S.A., Grazia Piras M., Longo D.L., Guralnik J., Hernandez D., Bandinelli S., Aigner E., Murphy A.T., Wroblewski V., Marroni F., Theurl I., Gnewuch C., Schadt E., Mitterer M., Schlessinger D., Ferrucci L., Witcher D.R., Hicks A.A., Weiss G., Uda M., Pramstaller P.P. Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels. Hum. Mol. Genet. 2011, 20:1232-1240.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1232-1240
-
-
Pichler, I.1
Minelli, C.2
Sanna, S.3
Tanaka, T.4
Schwienbacher, C.5
Naitza, S.6
Porcu, E.7
Pattaro, C.8
Busonero, F.9
Zanon, A.10
Maschio, A.11
Melville, S.A.12
Grazia Piras, M.13
Longo, D.L.14
Guralnik, J.15
Hernandez, D.16
Bandinelli, S.17
Aigner, E.18
Murphy, A.T.19
Wroblewski, V.20
Marroni, F.21
Theurl, I.22
Gnewuch, C.23
Schadt, E.24
Mitterer, M.25
Schlessinger, D.26
Ferrucci, L.27
Witcher, D.R.28
Hicks, A.A.29
Weiss, G.30
Uda, M.31
Pramstaller, P.P.32
more..
-
45
-
-
0030792094
-
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1
-
Rolfs A., Kvietikova I., Gassmann M., Wenger R.H. Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J. Biol. Chem. 1997, 272:20055-20062.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20055-20062
-
-
Rolfs, A.1
Kvietikova, I.2
Gassmann, M.3
Wenger, R.H.4
-
46
-
-
27744590510
-
Low serum transferrin levels in HFE C282Y homozygous subjects are associated with low CD8(+) T lymphocyte numbers
-
Macedo M.F., Cruz E., Lacerda R., Porto G., de Sousa M. Low serum transferrin levels in HFE C282Y homozygous subjects are associated with low CD8(+) T lymphocyte numbers. Blood Cells Mol. Dis. 2005, 35:319-325.
-
(2005)
Blood Cells Mol. Dis.
, vol.35
, pp. 319-325
-
-
Macedo, M.F.1
Cruz, E.2
Lacerda, R.3
Porto, G.4
de Sousa, M.5
-
47
-
-
84929492858
-
Common variants and haplotypes in the TF, TNF-alpha, and TMPRSS6 genes are associated with iron status in a female black South African population
-
Gichohi-Wainaina W.N., Melse-Boonstra A., Swinkels D.W., Zimmermann M.B., Feskens E.J., Towers G.W. Common variants and haplotypes in the TF, TNF-alpha, and TMPRSS6 genes are associated with iron status in a female black South African population. J. Nutr. 2015, 145:945-953.
-
(2015)
J. Nutr.
, vol.145
, pp. 945-953
-
-
Gichohi-Wainaina, W.N.1
Melse-Boonstra, A.2
Swinkels, D.W.3
Zimmermann, M.B.4
Feskens, E.J.5
Towers, G.W.6
-
48
-
-
84874688151
-
Intronic SNP rs3811647 of the human transferrin gene modulates its expression in hepatoma cells
-
Blanco-Rojo R., Bayele H.K., Srai S.K., Vaquero M.P. Intronic SNP rs3811647 of the human transferrin gene modulates its expression in hepatoma cells. Nutr. Hosp. 2012, 27:2142-2145.
-
(2012)
Nutr. Hosp.
, vol.27
, pp. 2142-2145
-
-
Blanco-Rojo, R.1
Bayele, H.K.2
Srai, S.K.3
Vaquero, M.P.4
-
49
-
-
79953321845
-
Genome-wide association study identifies genetic loci associated with iron deficiency
-
McLaren C.E., Garner C.P., Constantine C.C., McLachlan S., Vulpe C.D., Snively B.M., Gordeuk V.R., Nickerson D.A., Cook J.D., Leiendecker-Foster C., Beckman K.B., Eckfeldt J.H., Barcellos L.F., Murray J.A., Adams P.C., Acton R.T., Killeen A.A., McLaren G.D. Genome-wide association study identifies genetic loci associated with iron deficiency. PLoS One 2011, 6:e17390.
-
(2011)
PLoS One
, vol.6
, pp. e17390
-
-
McLaren, C.E.1
Garner, C.P.2
Constantine, C.C.3
McLachlan, S.4
Vulpe, C.D.5
Snively, B.M.6
Gordeuk, V.R.7
Nickerson, D.A.8
Cook, J.D.9
Leiendecker-Foster, C.10
Beckman, K.B.11
Eckfeldt, J.H.12
Barcellos, L.F.13
Murray, J.A.14
Adams, P.C.15
Acton, R.T.16
Killeen, A.A.17
McLaren, G.D.18
-
50
-
-
84897568562
-
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers
-
Stadhouders R., Aktuna S., Thongjuea S., Aghajanirefah A., Pourfarzad F., van Ijcken W., Lenhard B., Rooks H., Best S., Menzel S., Grosveld F., Thein S.L., Soler E. HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. J. Clin. Investig. 2014, 124:1699-1710.
-
(2014)
J. Clin. Investig.
, vol.124
, pp. 1699-1710
-
-
Stadhouders, R.1
Aktuna, S.2
Thongjuea, S.3
Aghajanirefah, A.4
Pourfarzad, F.5
van Ijcken, W.6
Lenhard, B.7
Rooks, H.8
Best, S.9
Menzel, S.10
Grosveld, F.11
Thein, S.L.12
Soler, E.13
-
52
-
-
74949090955
-
A genome-wide association analysis of serum iron concentrations
-
Tanaka T., Roy C.N., Yao W., Matteini A., Semba R.D., Arking D., Walston J.D., Fried L.P., Singleton A., Guralnik J., Abecasis G.R., Bandinelli S., Longo D.L., Ferrucci L. A genome-wide association analysis of serum iron concentrations. Blood 2010, 115:94-96.
-
(2010)
Blood
, vol.115
, pp. 94-96
-
-
Tanaka, T.1
Roy, C.N.2
Yao, W.3
Matteini, A.4
Semba, R.D.5
Arking, D.6
Walston, J.D.7
Fried, L.P.8
Singleton, A.9
Guralnik, J.10
Abecasis, G.R.11
Bandinelli, S.12
Longo, D.L.13
Ferrucci, L.14
-
53
-
-
0030050832
-
Dual function of the voltage-dependent Ca2+ channel alpha 2 delta subunit in current stimulation and subunit interaction
-
Gurnett C.A., De Waard M., Campbell K.P. Dual function of the voltage-dependent Ca2+ channel alpha 2 delta subunit in current stimulation and subunit interaction. Neuron 1996, 16:431-440.
-
(1996)
Neuron
, vol.16
, pp. 431-440
-
-
Gurnett, C.A.1
De Waard, M.2
Campbell, K.P.3
-
54
-
-
0036529824
-
Dehydration response of sickle cells to sickling-induced Ca(++) permeabilization
-
Lew V.L., Etzion Z., Bookchin R.M. Dehydration response of sickle cells to sickling-induced Ca(++) permeabilization. Blood 2002, 99:2578-2585.
-
(2002)
Blood
, vol.99
, pp. 2578-2585
-
-
Lew, V.L.1
Etzion, Z.2
Bookchin, R.M.3
-
55
-
-
84861187773
-
T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice
-
Kumfu S., Chattipakorn S., Chinda K., Fucharoen S., Chattipakorn N. T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice. Eur. J. Haematol. 2012, 88:535-548.
-
(2012)
Eur. J. Haematol.
, vol.88
, pp. 535-548
-
-
Kumfu, S.1
Chattipakorn, S.2
Chinda, K.3
Fucharoen, S.4
Chattipakorn, N.5
-
56
-
-
0141461407
-
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
-
Oudit G.Y., Sun H., Trivieri M.G., Koch S.E., Dawood F., Ackerley C., Yazdanpanah M., Wilson G.J., Schwartz A., Liu P.P., Backx P.H. L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy. Nat. Med. 2003, 9:1187-1194.
-
(2003)
Nat. Med.
, vol.9
, pp. 1187-1194
-
-
Oudit, G.Y.1
Sun, H.2
Trivieri, M.G.3
Koch, S.E.4
Dawood, F.5
Ackerley, C.6
Yazdanpanah, M.7
Wilson, G.J.8
Schwartz, A.9
Liu, P.P.10
Backx, P.H.11
-
57
-
-
74049102074
-
A case of iron overload cardiomyopathy: beneficial effects of iron chelating agent and calcium channel blocker on left ventricular dysfunction
-
Sugishita K., Asakawa M., Usui S., Takahashi T. A case of iron overload cardiomyopathy: beneficial effects of iron chelating agent and calcium channel blocker on left ventricular dysfunction. Int. Heart J. 2009, 50:829-838.
-
(2009)
Int. Heart J.
, vol.50
, pp. 829-838
-
-
Sugishita, K.1
Asakawa, M.2
Usui, S.3
Takahashi, T.4
-
58
-
-
0021821260
-
Genetic and environmental influences on the size and number of cells in the blood
-
Whitfield J.B., Martin N.G. Genetic and environmental influences on the size and number of cells in the blood. Genet. Epidemiol. 1985, 2:133-144.
-
(1985)
Genet. Epidemiol.
, vol.2
, pp. 133-144
-
-
Whitfield, J.B.1
Martin, N.G.2
-
59
-
-
50849144857
-
Variation of hemoglobin levels in normal Italian populations from genetic isolates
-
Sala C., Ciullo M., Lanzara C., Nutile T., Bione S., Massacane R., d'Adamo P., Gasparini P., Toniolo D., Camaschella C. Variation of hemoglobin levels in normal Italian populations from genetic isolates. Haematologica 2008, 93:1372-1375.
-
(2008)
Haematologica
, vol.93
, pp. 1372-1375
-
-
Sala, C.1
Ciullo, M.2
Lanzara, C.3
Nutile, T.4
Bione, S.5
Massacane, R.6
d'Adamo, P.7
Gasparini, P.8
Toniolo, D.9
Camaschella, C.10
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