Comparison of combination therapy of high-dose oral N-acetylcysteine and intravenous sodium bicarbonate hydration with individual therapies in the reduction of Contrast-induced Nephropathy during Cardiac Catheterisation and Percutaneous Coronary Intervention (CONTRAST): A multi-centre, randomised, controlled trial

International Journal of Cardiology

Volumn 201, Issue , 2015, Pages 237-242

  Chong, Eric ^a,b   Poh, Kian Keong ^a,c   Lu, Qingshu ^d   Zhang, James Jun Jie ^e   Tan, Ning ^f   Hou, Xu Min ^g   Ong, Hean Yee ^h   Azan, Aizai ⁱ   Chen, Shao Liang ^e   Chen, Ji Yan ^f   Ali, Rosli Mohd ⁱ   Fang, Wei Yi ^g   Lau, Titus Wai Leong ^a   Tan, Huay Cheem ^a,c  

^a NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^b Department of Medicine Jurong Health ^*  (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d SINGAPORE CLINICAL RESEARCH INSTITUTE   (Singapore)

^e NANJING MEDICAL UNIVERSITY   (China)

^f GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^g SHANGHAI CHEST HOSPITAL   (China)

^h KHOO TECK PUAT HOSPITAL   (Singapore)

ⁱ NATIONAL HEART INSTITUTE   (Malaysia)

Author keywords

Cardiac catheterization; Combination therapy; Contrast induced nephropathy; N acetylcysteine; Percutaneous coronary intervention; Sodium bicarbonate

Indexed keywords

ACETYLCYSTEINE; BICARBONATE; CONTRAST MEDIUM;

AGED; ARTICLE; CONTRAST INDUCED NEPHROPATHY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DRUG MEGADOSE; FEMALE; GLOMERULUS FILTRATION RATE; HEART CATHETERIZATION; HEMODIALYSIS; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MODERATE RENAL IMPAIRMENT; MORTALITY; MULTICENTER STUDY; OPEN STUDY; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; ADVERSE EFFECTS; CHEMICALLY INDUCED; CHINA; CLINICAL TRIAL; COMBINATION DRUG THERAPY; CORONARY ANGIOGRAPHY; DOSE RESPONSE; FLUID THERAPY; FOLLOW UP; INCIDENCE; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY FUNCTION TEST; MALAYSIA; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PROCEDURES; PROGNOSIS; RENAL INSUFFICIENCY; SINGAPORE; SURVIVAL RATE; TRENDS;

ACETYLCYSTEINE; ADMINISTRATION, ORAL; AGED; CARDIAC CATHETERIZATION; CHINA; CONTRAST MEDIA; CORONARY ANGIOGRAPHY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; FLUID THERAPY; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HUMANS; INCIDENCE; INFUSIONS, INTRAVENOUS; KIDNEY FUNCTION TESTS; MALAYSIA; MALE; PERCUTANEOUS CORONARY INTERVENTION; PROGNOSIS; RENAL INSUFFICIENCY; SINGAPORE; SODIUM BICARBONATE; SURVIVAL RATE;

EID: 84943553251     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.07.108     Document Type: Article

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