-
1
-
-
0031920799
-
Cancer phase I clinical trials: Efficient dose escalation with overdose control
-
Babb J, Rogatko A, Zacks S (1998) Cancer phase I clinical trials: Efficient dose escalation with overdose control. Stat Med 17:1103-1120
-
(1998)
Stat Med
, vol.17
, pp. 1103-1120
-
-
Babb, J.1
Rogatko, A.2
Zacks, S.3
-
2
-
-
2142670647
-
Dose-finding based on multiple toxicities in a soft tissue sarcoma trial
-
Bekele BN, Thall PF (2004) Dose-finding based on multiple toxicities in a soft tissue sarcoma trial. J Am Stat Assoc 99:26-35
-
(2004)
J Am Stat Assoc
, vol.99
, pp. 26-35
-
-
Bekele, B.N.1
Thall, P.F.2
-
3
-
-
45849147269
-
Monitoring late-onset toxicities in phase I trials using predicted risks
-
Bekele BN, Yuan J, Shen Y, Thall PF (2008) Monitoring late-onset toxicities in phase I trials using predicted risks. Biostatistics 9:442-457
-
(2008)
Biostatistics
, vol.9
, pp. 442-457
-
-
Bekele, B.N.1
Yuan, J.2
Shen, Y.3
Thall, P.F.4
-
4
-
-
0036277621
-
The bivariate continual reassessment method: Extending the CRM to phase I trials of two competing outcomes
-
Braun TM (2002) The bivariate continual reassessment method: Extending the CRM to phase I trials of two competing outcomes. Contr Clin Trials 23:240-256
-
(2002)
Contr Clin Trials
, vol.23
, pp. 240-256
-
-
Braun, T.M.1
-
5
-
-
50849150633
-
The feasibility of using randomization schemes early in the clinical trials of new chemotherapeutic agents: Hydroxyurea
-
Carbone PP, Krant MJ, Miller SP, Hall TC, Shnider BI, Colsky J, Horton J, Hosley H, Miller JM, Frie E, Schneiderman M (1965) The feasibility of using randomization schemes early in the clinical trials of new chemotherapeutic agents: Hydroxyurea. Clin Pharmacol Therapeut 6:17-24
-
(1965)
Clin Pharmacol Therapeut
, vol.6
, pp. 17-24
-
-
Carbone, P.P.1
Krant, M.J.2
Miller, S.P.3
Hall, T.C.4
Shnider, B.I.5
Colsky, J.6
Horton, J.7
Hosley, H.8
Miller, J.M.9
Frie, E.10
Schneiderman, M.11
-
6
-
-
0036188788
-
On the use of nonparametric curves in phase I trials with low toxicity tolerance
-
Cheung YK (2002) On the use of nonparametric curves in phase I trials with low toxicity tolerance. Biometrics 58:237-240
-
(2002)
Biometrics
, vol.58
, pp. 237-240
-
-
Cheung, Y.K.1
-
7
-
-
27944494441
-
Coherence principles in dose-finding studies
-
Cheung YK (2005) Coherence principles in dose-finding studies. Biometrika 92:863-873
-
(2005)
Biometrika
, vol.92
, pp. 863-873
-
-
Cheung, Y.K.1
-
8
-
-
84957974628
-
Dose-finding with delayed binary outcomes in cancer trials
-
In: Chevret S (ed). Wiley, NY
-
Cheung YK (2006) Dose-finding with delayed binary outcomes in cancer trials. In: Chevret S (ed) Statistical method for dose-finding experiments. Wiley, NY, pp 225-242
-
(2006)
Statistical method for dose-finding experiments
, pp. 225-242
-
-
Cheung, Y.K.1
-
9
-
-
38349062295
-
Sequential implementation of stepwise procedures for identifying the maximum tolerated dose
-
Cheung YK (2007) Sequential implementation of stepwise procedures for identifying the maximum tolerated dose. J Am Stat Assoc 102:1448-1461
-
(2007)
J Am Stat Assoc
, vol.102
, pp. 1448-1461
-
-
Cheung, Y.K.1
-
10
-
-
84871180729
-
Dose-finding by the continual reassessment method, R package version 0.1-2
-
Cheung YK (2008) Dose-finding by the continual reassessment method, R package version 0.1-2. http://www.r-project.org
-
(2008)
-
-
Cheung, Y.K.1
-
11
-
-
0033637096
-
Sequential designs for phase I clinical trials with late-onset toxicities
-
Cheung YK, Chappell R (2000) Sequential designs for phase I clinical trials with late-onset toxicities. Biometrics 56:1177-1182
-
(2000)
Biometrics
, vol.56
, pp. 1177-1182
-
-
Cheung, Y.K.1
Chappell, R.2
-
12
-
-
0036712359
-
A simple technique to evaluate model sensitivity in the continual reassessment method
-
Cheung YK, Chappell R (2002) A simple technique to evaluate model sensitivity in the continual reassessment method. Biometrics 58:671-674
-
(2002)
Biometrics
, vol.58
, pp. 671-674
-
-
Cheung, Y.K.1
Chappell, R.2
-
13
-
-
77249122114
-
Stochastic approximation with virtual observations for dose finding on discrete levels
-
Cheung YK, Elkind MSV (2010) Stochastic approximation with virtual observations for dose finding on discrete levels. Biometrika 97:109-121
-
(2010)
Biometrika
, vol.97
, pp. 109-121
-
-
Cheung, Y.K.1
Elkind, M.S.V.2
-
14
-
-
33845418269
-
Selecting promising ALS therapies in clinical trials
-
Cheung YK, Gordon PH, Levin B (2006) Selecting promising ALS therapies in clinical trials. Neurology 67:1748-1751
-
(2006)
Neurology
, vol.67
, pp. 1748-1751
-
-
Cheung, Y.K.1
Gordon, P.H.2
Levin, B.3
-
15
-
-
0000901511
-
A method for obtaining and analyzing sensitivity data
-
Dixon WJ, Mood AM (1948) A method for obtaining and analyzing sensitivity data. J Am Stat Assoc 60:967-978
-
(1948)
J Am Stat Assoc
, vol.60
, pp. 967-978
-
-
Dixon, W.J.1
Mood, A.M.2
-
18
-
-
48849116060
-
The Neuroprotection with statin therapy for acute recovery trial (NeuSTART): An adaptive design phase I dose-escalation study of high-dose lovastatin in acute ischeme stroke
-
Elkind MSV, Sacco RL, MacArthur RB, Fink DJ, Peerschke E, Andrews H, Neils G, Stillman J, Corporan T, Leifer D, Cheung K (2008) The Neuroprotection with statin therapy for acute recovery trial (NeuSTART): An adaptive design phase I dose-escalation study of high-dose lovastatin in acute ischeme stroke. Int J Stroke 3:210-218
-
(2008)
Int J Stroke
, vol.3
, pp. 210-218
-
-
Elkind, M.S.V.1
Sacco, R.L.2
MacArthur, R.B.3
Fink, D.J.4
Peerschke, E.5
Andrews, H.6
Neils, G.7
Stillman, J.8
Corporan, T.9
Leifer, D.10
Cheung, K.11
-
19
-
-
0028060511
-
Practical modifications of the continal reassessment method for phase I cancer trials
-
Faires D (1994) Practical modifications of the continal reassessment method for phase I cancer trials. J Biopharm Stat 4:147-164
-
(1994)
J Biopharm Stat
, vol.4
, pp. 147-164
-
-
Faires, D.1
-
20
-
-
0033918775
-
A curve-free method for phase I clinical trials
-
Gasparini M, Eisele J (2000) A curve-free method for phase I clinical trials. Biometrics 56:609- 615
-
(2000)
Biometrics
, vol.56
, pp. 609-615
-
-
Gasparini, M.1
Eisele, J.2
-
21
-
-
0029027770
-
Some practical improvements in the continual reassessment method for phase I studies
-
Goodman SN, Zahurak ML, Piantadosi S (1995) Some practical improvements in the continual reassessment method for phase I studies. Stat Med 14:1149-1161
-
(1995)
Stat Med
, vol.14
, pp. 1149-1161
-
-
Goodman, S.N.1
Zahurak, M.L.2
Piantadosi, S.3
-
22
-
-
34548619360
-
Dose-finding in phase I clinical trials based on toxicity probability intervals
-
Ji Y, Li Y, Bekele BN (2007) Dose-finding in phase I clinical trials based on toxicity probability intervals. Clin Trials 4:235-244
-
(2007)
Clin Trials
, vol.4
, pp. 235-244
-
-
Ji, Y.1
Li, Y.2
Bekele, B.N.3
-
23
-
-
0028170238
-
A comparison of two phase I trial designs
-
Korn EL, Midthune D, Chen TT, Rubinstein LV, Christian MC, Simon RM (1994) A comparison of two phase I trial designs. Stat Med 13:1799-1806
-
(1994)
Stat Med
, vol.13
, pp. 1799-1806
-
-
Korn, E.L.1
Midthune, D.2
Chen, T.T.3
Rubinstein, L.V.4
Christian, M.C.5
Simon, R.M.6
-
24
-
-
84858252858
-
Validation of toxicity burden score for use in phase I clinical trials
-
Lee SM, Hershman D, Martin P, Leonard J, Cheung K (2009) Validation of toxicity burden score for use in phase I clinical trials. J Clin Oncol 27 (Suppl.), 15s (abstr. 2514)
-
(2009)
J Clin Oncol
, vol.27
, pp. 15s
-
-
Lee, S.M.1
Hershman, D.2
Martin, P.3
Leonard, J.4
Cheung, K.5
-
25
-
-
79953141091
-
Continual reassessment method with multiple toxicity constraints
-
Lee SM, Cheng B, Cheung YK (2001) Continual reassessment method with multiple toxicity constraints. Biostatistics. 12:386-398
-
(2001)
Biostatistics.
, vol.12
, pp. 386-398
-
-
Lee, S.M.1
Cheng, B.2
Cheung, Y.K.3
-
26
-
-
33745892167
-
Phase I/II trial of bortezomib plus CHOP-Rituximab in diffuse large B cell (DLBCL) and mantle cell lymphoma (MCL): Phase I results
-
Leonard JP, Furman RR, Cheung YKK, Feldman EJ, Cho HJ, Vose JM, Nichols G, Glynn PW, Joyce MA, Ketas J, Ruan J, Carew J, Niesvizky R, LaCasce A, Chadburn A, Cesarman E, Coleman M (2005) Phase I/II trial of bortezomib plus CHOP-Rituximab in diffuse large B cell (DLBCL) and mantle cell lymphoma (MCL): Phase I results. Blood 106:147A-147A
-
(2005)
Blood
, vol.106
, pp. 147A-147A
-
-
Leonard, J.P.1
Furman, R.R.2
Cheung, Y.K.K.3
Feldman, E.J.4
Cho, H.J.5
Vose, J.M.6
Nichols, G.7
Glynn, P.W.8
Joyce, M.A.9
Ketas, J.10
Ruan, J.11
Carew, J.12
Niesvizky, R.13
LaCasce, A.14
Chadburn, A.15
Cesarman, E.16
Coleman, M.17
-
27
-
-
0024995772
-
Sequential designs in bioassay
-
McLeish DL, Tosh D (1990) Sequential designs in bioassay. Biometrics 46:103-116
-
(1990)
Biometrics
, vol.46
, pp. 103-116
-
-
McLeish, D.L.1
Tosh, D.2
-
28
-
-
1342289781
-
A phase I trial using the time-to-event continual reassessment strategy to escalate cisplatin with gemcitabine and radiation therapy for pancreatic cancer
-
Muller J, McGinn C, Normolle D et al (2004) A phase I trial using the time-to-event continual reassessment strategy to escalate cisplatin with gemcitabine and radiation therapy for pancreatic cancer. J Clin Oncol 22:238-243
-
(2004)
J Clin Oncol
, vol.22
, pp. 238-243
-
-
Muller, J.1
McGinn, C.2
Normolle, D.3
-
29
-
-
0000691109
-
Applications of a method for the efficient computation of posterior distributions
-
Naylor J, Smith A (1982) Applications of a method for the efficient computation of posterior distributions. Appl Stat 31:214-225
-
(1982)
Appl Stat
, vol.31
, pp. 214-225
-
-
Naylor, J.1
Smith, A.2
-
30
-
-
33749063821
-
Designing dose-escalation trials with late-onset toxicities using the time-to-event continual reassessment method
-
Normolle D, Lawrence T (2006) Designing dose-escalation trials with late-onset toxicities using the time-to-event continual reassessment method. J Clin Oncol 24:4426-4433
-
(2006)
J Clin Oncol
, vol.24
, pp. 4426-4433
-
-
Normolle, D.1
Lawrence, T.2
-
31
-
-
0029938415
-
Continual reassessment method: A likelihood approach
-
O'Quigley J, Shen LZ (1996) Continual reassessment method: A likelihood approach. Biometrics 52:673-684
-
(1996)
Biometrics
, vol.52
, pp. 673-684
-
-
O'Quigley, J.1
Shen, L.Z.2
-
32
-
-
0025148278
-
Continual reassessment method: A practical design for phase I clinical trials in cancer
-
O'Quigley J, PepeM, Fisher L (1990) Continual reassessment method: A practical design for phase I clinical trials in cancer. Biometrics 46:33-48
-
(1990)
Biometrics
, vol.46
, pp. 33-48
-
-
O'Quigley, J.1
Pepe, M.2
Fisher, L.3
-
34
-
-
5344244656
-
R: A language and environment for statistical computing
-
R Foundation for Statistical Computing, Vienna, Austria
-
R Development Core Team (2008) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0, http://www.r-project.org
-
(2008)
-
-
-
35
-
-
0027524863
-
Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents
-
Ratain MJ, Mick R, Schilsky RL, Siegler M (1993) Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents. J Natl Cancer Inst 85:1637- 1643
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1637-1643
-
-
Ratain, M.J.1
Mick, R.2
Schilsky, R.L.3
Siegler, M.4
-
36
-
-
33644841960
-
The best guess approach to phase I trial design
-
Rosa DD, Harris J, Jayson GC (2006) The best guess approach to phase I trial design. J Clin Oncol 24:206-208
-
(2006)
J Clin Oncol
, vol.24
, pp. 206-208
-
-
Rosa, D.D.1
Harris, J.2
Jayson, G.C.3
-
38
-
-
33746402001
-
Consistency of continual reassessment method under model misspecification
-
Shen LZ, O'Quigley J (1996) Consistency of continual reassessment method under model misspecification. Biometrika 83:395-405
-
(1996)
Biometrika
, vol.83
, pp. 395-405
-
-
Shen, L.Z.1
O'Quigley, J.2
-
39
-
-
0030749549
-
Accelerated titration designs for phase I clinical trials in oncology
-
Simon R, Freidlin B, Rubinstein L, Arbuck SG, Collins J, Christian MC (1997) Accelerated titration designs for phase I clinical trials in oncology. J Natl Cancer Inst 89:1138-1147
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1138-1147
-
-
Simon, R.1
Freidlin, B.2
Rubinstein, L.3
Arbuck, S.G.4
Collins, J.5
Christian, M.C.6
-
40
-
-
0024452804
-
Design and analysis of phase I clinical trials
-
Storer B (1989) Design and analysis of phase I clinical trials. Biometrics 45:925-937
-
(1989)
Biometrics
, vol.45
, pp. 925-937
-
-
Storer, B.1
-
41
-
-
0023554115
-
Current phase I/II designs: Are they adequate?
-
Storer B, DeMets D (1987) Current phase I/II designs: Are they adequate? J Clin Res Drug Dev 1:121-130
-
(1987)
J Clin Res Drug Dev
, vol.1
, pp. 121-130
-
-
Storer, B.1
DeMets, D.2
-
42
-
-
4444272419
-
Dose-finding based on efficacy-toxicity trade-offs
-
Thall PF, Cook JD (2004) Dose-finding based on efficacy-toxicity trade-offs. Biometrics 60:684- 693
-
(2004)
Biometrics
, vol.60
, pp. 684-693
-
-
Thall, P.F.1
Cook, J.D.2
-
43
-
-
0000090155
-
Sequential tests of statistical hypotheses
-
Wald A (1945) Sequential tests of statistical hypotheses. Ann Math Stat 16:117-186
-
(1945)
Ann Math Stat
, vol.16
, pp. 117-186
-
-
Wald, A.1
-
44
-
-
0000193326
-
Optimum character of the sequential probability ratio test
-
Wald A, Wolfowitz J (1948) Optimum character of the sequential probability ratio test. Ann Math Stat 19:326-339
-
(1948)
Ann Math Stat
, vol.19
, pp. 326-339
-
-
Wald, A.1
Wolfowitz, J.2
-
45
-
-
33748795036
-
Bayesian dose-finding in phase I/II clinical trials using toxicity and efficacy odds ratio
-
Yin G, Li Y, Ji Y (2006) Bayesian dose-finding in phase I/II clinical trials using toxicity and efficacy odds ratio. Biometrics 62:777-787
-
(2006)
Biometrics
, vol.62
, pp. 777-787
-
-
Yin, G.1
Li, Y.2
Ji, Y.3
-
46
-
-
34247276015
-
The continual reassessment method for multiple toxicity grades: a Bayesian quasi-likelihood approach
-
Yuan Z, Chappell R, Bailey H (2007) The continual reassessment method for multiple toxicity grades: a Bayesian quasi-likelihood approach. Biometrics 63:173-179
-
(2007)
Biometrics
, vol.63
, pp. 173-179
-
-
Yuan, Z.1
Chappell, R.2
Bailey, H.3
-
47
-
-
0032525496
-
Optimal Bayesian-feasible dose escalation for cancer phase I trials
-
Zacks S, Rogatko A, Babb J (1998) Optimal Bayesian-feasible dose escalation for cancer phase I trials. Stat Probab Lett 38:215-220
-
(1998)
Stat Probab Lett
, vol.38
, pp. 215-220
-
-
Zacks, S.1
Rogatko, A.2
Babb, J.3
|