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Volumn 52, Issue 2, 1996, Pages 673-684

Continual reassessment method: A likelihood approach

Author keywords

Clinical trial; Continual reassessment method; Dose escalation; Dose finding studies; Maximum likelihood; Phase 1 trial; Toxicity

Indexed keywords

BAYESIAN NETWORKS; TOXICITY;

EID: 0029938415     PISSN: 0006341X     EISSN: None     Source Type: Journal    
DOI: 10.2307/2532905     Document Type: Article
Times cited : (299)

References (9)
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    • Chevret, S.1
  • 3
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    • Model-guided determination of maximum tolerated dose in Phase I clinical trials: Evidence for increased precision
    • Mick, R. and Ratain, M. J. (1993). Model-guided determination of maximum tolerated dose in Phase I clinical trials: Evidence for increased precision. Journal of the National Cancer Institute 85(3), 217-223.
    • (1993) Journal of the National Cancer Institute , vol.85 , Issue.3 , pp. 217-223
    • Mick, R.1    Ratain, M.J.2
  • 4
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    • Estimating the probability of toxicity at the recommended dose following a Phase I clinical trial in cancer
    • O'Quigley, J. (1992). Estimating the probability of toxicity at the recommended dose following a Phase I clinical trial in cancer. Biometrics 48, 853-862.
    • (1992) Biometrics , vol.48 , pp. 853-862
    • O'Quigley, J.1
  • 5
    • 0025148278 scopus 로고
    • Continual reassessment method: A practical design for Phase I clinical trials in cancer
    • O'Quigley, J., Pepe, M., and Fisher, L. (1990). Continual reassessment method: A practical design for Phase I clinical trials in cancer. Biometrics 46, 33-48.
    • (1990) Biometrics , vol.46 , pp. 33-48
    • O'Quigley, J.1    Pepe, M.2    Fisher, L.3
  • 6
    • 0025986460 scopus 로고
    • Methods for dose finding studies in cancer clinical trials: A review and results of a Monte Carlo study
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    • (1991) Statistics in Medicine , vol.10 , pp. 1647-1664
    • O'Quigley, J.1    Chevret, S.2
  • 7
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    • Consistency of continual reassessment method in dose finding studies
    • in press
    • Shen, L. Z. and O'Quigley, J. (1996). Consistency of continual reassessment method in dose finding studies. Biometrika, in press.
    • (1996) Biometrika
    • Shen, L.Z.1    O'Quigley, J.2
  • 8
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    • On the existence of maximum likelihood estimators for the binomial response models
    • Silvapulle, M. J. (1981). On the existence of maximum likelihood estimators for the binomial response models. Journal of the Royal Statistical Society, Series B 43(3), 310-313.
    • (1981) Journal of the Royal Statistical Society, Series B , vol.43 , Issue.3 , pp. 310-313
    • Silvapulle, M.J.1
  • 9
    • 0024452804 scopus 로고
    • Design and analysis of Phase I clinical trials
    • Storer, B. E. (1989). Design and analysis of Phase I clinical trials. Biometrics 45, 925-937.
    • (1989) Biometrics , vol.45 , pp. 925-937
    • Storer, B.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.