Signal strength and metabolic requirements control cytokine-induced Th17 differentiation of uncommitted human T cells

Journal of Immunology

Volumn 195, Issue 8, 2015, Pages 3617-3627

  Kastirr, Ilko ^a,b,c   Crosti, Mariacristina ^a   Maglie, Stefano ^a   Paroni, Moira ^a   Steckel, Bodo ^b,c   Moro, Monica ^a   Pagani, Massimilliano ^a,d   Abrignani, Sergio ^a,d   Geginat, Jens ^a  

^a Istituto Nazionale di Genetica Molecolare   (Italy)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CHEMOKINE RECEPTOR CCR6; FAS ANTIGEN; GAMMA INTERFERON; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 22; INTERLEUKIN 23 RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; RETINOID RELATED ORPHAN RECEPTOR GAMMA; RORC2 PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; CCR6 PROTEIN, HUMAN; IFNG PROTEIN, HUMAN; IL23R PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; INTERLEUKIN RECEPTOR; INTERLEUKIN-22; RORC PROTEIN, HUMAN;

ARTICLE; CD4+ T LYMPHOCYTE; CELL DENSITY; CELL METABOLISM; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; EX VIVO STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; UPREGULATION; CELL DIFFERENTIATION; CYTOLOGY; FEMALE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MALE; PHYSIOLOGY;

CELL DIFFERENTIATION; FEMALE; HUMANS; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; INTERLEUKINS; MALE; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; RECEPTORS, CCR6; RECEPTORS, INTERLEUKIN; SIGNAL TRANSDUCTION; TH17 CELLS;

EID: 84943516855     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1501016     Document Type: Article

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