A Photoactivatable AIE Polymer for Light-Controlled Gene Delivery: Concurrent Endo/Lysosomal Escape and DNA Unpacking

Angewandte Chemie - International Edition

Volumn 54, Issue 39, 2015, Pages 11419-11423

  Yuan, Youyong ^a   Zhang, Chong Jing ^a   Liu, Bin ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

Author keywords

aggregation induced emission; endo lysosomes; gene delivery; polymers; reactive oxygen species

Indexed keywords

COPOLYMERS; DNA; GENE TRANSFER; GENES; LIGHT; NUCLEIC ACIDS; PHOTOSENSITIZERS;

AGGREGATION-INDUCED EMISSIONS; ENDO/LYSOSOMES; GENE DELIVERY; GENE DELIVERY VECTORS; LIGHT EXCITATION; PHOTOACTIVATABLE; REACTIVE OXYGEN SPECIES; VISIBLE-LIGHT IRRADIATION;

POLYMERS;

DNA; NANOPARTICLE; POLYMER; REACTIVE OXYGEN METABOLITE;

CHEMISTRY; ENDOSOME; GENE TRANSFER; HELA CELL LINE; HUMAN; LIGHT; LYSOSOME; METABOLISM; PHOTOCHEMISTRY; STATIC ELECTRICITY;

DNA; ENDOSOMES; GENE TRANSFER TECHNIQUES; HELA CELLS; HUMANS; LIGHT; LYSOSOMES; NANOPARTICLES; PHOTOCHEMICAL PROCESSES; POLYMERS; REACTIVE OXYGEN SPECIES; STATIC ELECTRICITY;

EID: 84943457700     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201503640     Document Type: Article

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