-
1
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K. & Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 (2006).
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
2
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
-
3
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu, J. et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920 (2007).
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
-
4
-
-
84863798923
-
Human pluripotency: A difficult state to make smart choices
-
Rampalli, S. & Bhatia, M. Human pluripotency: a difficult state to make smart choices. Cell cycle 11, 2411-2412 (2012).
-
(2012)
Cell Cycle
, vol.11
, pp. 2411-2412
-
-
Rampalli, S.1
Bhatia, M.2
-
5
-
-
38649094609
-
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells
-
Brambrink, T. et al. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell stem cell 2, 151-159 (2008).
-
(2008)
Cell Stem Cell
, vol.2
, pp. 151-159
-
-
Brambrink, T.1
-
6
-
-
58249085824
-
Role of the murine reprogramming factors in the induction of pluripotency
-
Sridharan, R. et al. Role of the murine reprogramming factors in the induction of pluripotency. Cell 136, 364-377 (2009).
-
(2009)
Cell
, vol.136
, pp. 364-377
-
-
Sridharan, R.1
-
7
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li, R. et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell stem cell 7, 51-63 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
-
8
-
-
84870058502
-
Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome
-
Soufi, A., Donahue, G. & Zaret, K. S. Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell 151, 994-1004 (2012).
-
(2012)
Cell
, vol.151
, pp. 994-1004
-
-
Soufi, A.1
Donahue, G.2
Zaret, K.S.3
-
9
-
-
78650996389
-
Reprogramming factor expression initiates widespread targeted chromatin remodeling
-
Koche, R. P. et al. Reprogramming factor expression initiates widespread targeted chromatin remodeling. Cell Stem Cell 8, 96-105 (2011).
-
(2011)
Cell Stem Cell
, vol.8
, pp. 96-105
-
-
Koche, R.P.1
-
10
-
-
78650467973
-
Open chromatin in pluripotency and reprogramming
-
Gaspar-Maia, A., Alajem, A., Meshorer, E. & Ramalho-Santos, M. Open chromatin in pluripotency and reprogramming. Nat Rev Mol Cell Biol 12, 36-47 (2011).
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 36-47
-
-
Gaspar-Maia, A.1
Alajem, A.2
Meshorer, E.3
Ramalho-Santos, M.4
-
11
-
-
84865112255
-
The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming
-
Mansour, A. A. et al. The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming. Nature 488, 409-413 (2012).
-
(2012)
Nature
, vol.488
, pp. 409-413
-
-
Mansour, A.A.1
-
12
-
-
84859218238
-
Chromatin-modifying enzymes as modulators of reprogramming
-
Onder, T. T. et al. Chromatin-modifying enzymes as modulators of reprogramming. Nature 483, 598-602 (2012).
-
(2012)
Nature
, vol.483
, pp. 598-602
-
-
Onder, T.T.1
-
13
-
-
82755187396
-
The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner
-
Wang, T. et al. The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. Cell Stem Cell 9, 575-587 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 575-587
-
-
Wang, T.1
-
14
-
-
8844265508
-
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
-
Ringrose, L. & Paro, R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet 38, 413-443 (2004).
-
(2004)
Annu Rev Genet
, vol.38
, pp. 413-443
-
-
Ringrose, L.1
Paro, R.2
-
15
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
Lee, T. I. et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125, 301-313 (2006).
-
(2006)
Cell
, vol.125
, pp. 301-313
-
-
Lee, T.I.1
-
16
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B. E. et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326 (2006).
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
17
-
-
33646872978
-
Chromatin signatures of pluripotent cell lines
-
Azuara, V. et al. Chromatin signatures of pluripotent cell lines. Nat Cell Biol 8, 532-538 (2006).
-
(2006)
Nat Cell Biol
, vol.8
, pp. 532-538
-
-
Azuara, V.1
-
18
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer, L. A. et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441, 349-353 (2006).
-
(2006)
Nature
, vol.441
, pp. 349-353
-
-
Boyer, L.A.1
-
19
-
-
0034977239
-
The polycomb-group gene Ezh2 is required for early mouse development
-
O'Carroll, D. et al. The polycomb-group gene Ezh2 is required for early mouse development. Mol Cell Biol 21, 4330-4336 (2001).
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4330-4336
-
-
O'Carroll, D.1
-
20
-
-
8144230178
-
Suz12 is essential for mouse development and for EZH2 histonemethyltransferase activity
-
Pasini, D., Bracken, A. P., Jensen, M. R., Lazzerini Denchi, E. & Helin, K. Suz12 is essential for mouse development and for EZH2 histonemethyltransferase activity. EMBO J 23, 4061-4071 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 4061-4071
-
-
Pasini, D.1
Bracken, A.P.2
Jensen, M.R.3
Lazzerini Denchi, E.4
Helin, K.5
-
21
-
-
7544230144
-
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
-
Caretti, G., Di Padova, M.,Micales, B., Lyons, G. E. & Sartorelli, V. The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev 18, 2627-2638 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 2627-2638
-
-
Caretti, G.1
Di Padova, M.2
Micales, B.3
Lyons, G.E.4
Sartorelli, V.5
-
22
-
-
33344469959
-
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
-
Kamminga, L. M. et al. The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood 107, 2170-2179 (2006).
-
(2006)
Blood
, vol.107
, pp. 2170-2179
-
-
Kamminga, L.M.1
-
23
-
-
84899096353
-
The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation
-
Ding, X. et al. The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation. Stem Cells Dev 23, 931-940 (2014).
-
(2014)
Stem Cells Dev
, vol.23
, pp. 931-940
-
-
Ding, X.1
-
24
-
-
77953086963
-
ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency
-
Pereira, C. F. et al. ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency. Cell Stem Cell 6, 547-556 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 547-556
-
-
Pereira, C.F.1
-
25
-
-
84866369892
-
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase
-
Buganim, Y. et al. Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase. Cell 150, 1209-1222 (2012).
-
(2012)
Cell
, vol.150
, pp. 1209-1222
-
-
Buganim, Y.1
-
26
-
-
33947134834
-
The Polycomb group proteins bind throughout the INK4AARF locus and are disassociated in senescent cells
-
Bracken, A. P. et al. The Polycomb group proteins bind throughout the INK4AARF locus and are disassociated in senescent cells. Genes Dev 21, 525-530 (2007).
-
(2007)
Genes Dev
, vol.21
, pp. 525-530
-
-
Bracken, A.P.1
-
27
-
-
79954471872
-
EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression
-
Fan, T. et al. EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression. Mol Cancer Res 9, 418-429 (2011).
-
(2011)
Mol Cancer Res
, vol.9
, pp. 418-429
-
-
Fan, T.1
-
29
-
-
77956320116
-
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
Samavarchi-Tehrani, P. et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 7, 64-77 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
-
30
-
-
70350732790
-
A chemical platform for improved induction of human iPSCs
-
Lin, T. et al. A chemical platform for improved induction of human iPSCs. Nat Methods 6, 805-808 (2009).
-
(2009)
Nat Methods
, vol.6
, pp. 805-808
-
-
Lin, T.1
-
31
-
-
48449084118
-
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
-
Marson, A. et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 134, 521-533 (2008).
-
(2008)
Cell
, vol.134
, pp. 521-533
-
-
Marson, A.1
-
32
-
-
84869002238
-
The functions of microRNAs in pluripotency and reprogramming
-
Leonardo, T. R., Schultheisz, H. L., Loring, J. F. & Laurent, L. C. The functions of microRNAs in pluripotency and reprogramming. Nat Cell Biol 14, 1114-1121 (2012).
-
(2012)
Nat Cell Biol
, vol.14
, pp. 1114-1121
-
-
Leonardo, T.R.1
Schultheisz, H.L.2
Loring, J.F.3
Laurent, L.C.4
-
33
-
-
84856006660
-
MIR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition
-
Zhang, Z., Liu, S., Shi, R. & Zhao, G. miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition. Cancer Genet 204, 486-491 (2011).
-
(2011)
Cancer Genet
, vol.204
, pp. 486-491
-
-
Zhang, Z.1
Liu, S.2
Shi, R.3
Zhao, G.4
-
34
-
-
84864976790
-
MIR-23a regulates TGF-b-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells
-
Cao, M. et al. miR-23a regulates TGF-b-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells. Int. J Oncol 41, 869-875 (2012).
-
(2012)
Int. J Oncol
, vol.41
, pp. 869-875
-
-
Cao, M.1
-
35
-
-
70349093119
-
Senescence impairs successful reprogramming to pluripotent stem cells
-
Banito,A. et al. Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev 23, 2134-2139 (2009).
-
(2009)
Genes Dev
, vol.23
, pp. 2134-2139
-
-
Banito, A.1
-
36
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
Hong, H. et al. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460, 1132-1135 (2009).
-
(2009)
Nature
, vol.460
, pp. 1132-1135
-
-
Hong, H.1
-
37
-
-
0346363757
-
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
-
Peinado, H., Ballestar, E., Esteller, M. & Cano, A. Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol 24, 306-319 (2004).
-
(2004)
Mol Cell Biol
, vol.24
, pp. 306-319
-
-
Peinado, H.1
Ballestar, E.2
Esteller, M.3
Cano, A.4
-
38
-
-
84874781927
-
Cell reprogramming requires silencing of a core subset of polycomb targets
-
Fragola, G. et al. Cell reprogramming requires silencing of a core subset of polycomb targets. PLoS Genet 9, e1003292 (2013).
-
(2013)
PLoS Genet
, vol.9
-
-
Fragola, G.1
-
39
-
-
62349130698
-
Ultrafast and memoryefficient alignment of short DNA sequences to the human genome
-
Langmead, B., Trapnell, C., Pop, M. & Salzberg, S. L. Ultrafast and memoryefficient alignment of short DNA sequences to the human genome. Genome Biol 10, R25 (2009).
-
(2009)
Genome Biol
, vol.10
, pp. R25
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
40
-
-
75249087100
-
EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
-
Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139-140 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 139-140
-
-
Robinson, M.D.1
McCarthy, D.J.2
Smyth, G.K.3
-
41
-
-
84864464973
-
DIANA miRPath v.2.0: Investigating the combinatorial effect of microRNAs in pathways
-
Vlachos, I. S. et al. DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nuc Acids Res 40, W498-504 (2012).
-
(2012)
Nuc Acids Res
, vol.40
, pp. W498-504
-
-
Vlachos, I.S.1
-
42
-
-
36849043170
-
P38 MAPKsignaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation
-
Rampalli, S. et al. p38 MAPKsignaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nat Struc Mol Biol 14, 1150-1156 (2007).
-
(2007)
Nat Struc Mol Biol
, vol.14
, pp. 1150-1156
-
-
Rampalli, S.1
|