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Volumn 17, Issue 12, 2015, Pages

The Value of Macrolide-Based Regimens for Community-Acquired Pneumonia

Author keywords

Community acquired pneumonia; Macrolide antimicrobials; Macrolide based regimens; Respiratory tract infections

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; BETA LACTAM ANTIBIOTIC; CETHROMYCIN; CIPROFLOXACIN; CLARITHROMYCIN; KETOLIDE; LEVOFLOXACIN; MACROLIDE; PLACEBO;

EID: 84943388174     PISSN: 15233847     EISSN: 15343146     Source Type: Journal    
DOI: 10.1007/s11908-015-0507-4     Document Type: Review
Times cited : (7)

References (85)
  • 1
    • 0035950132 scopus 로고    scopus 로고
    • Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
    • COI: 1:CAS:528:DC%2BD3MXotFyksbs%3D, PID: 11677599
    • Schlunzen F, Zarivach R, Harms J, et al. Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature. 2001;413(6858):814–21. doi:10.1038/35101544.
    • (2001) Nature , vol.413 , Issue.6858 , pp. 814-821
    • Schlunzen, F.1    Zarivach, R.2    Harms, J.3
  • 2
    • 0038690158 scopus 로고    scopus 로고
    • The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome
    • COI: 1:CAS:528:DC%2BD3sXlt1aqurY%3D, PID: 12860123
    • Tenson T, Lovmar M, Ehrenberg M. The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol. 2003;330(5):1005–14.
    • (2003) J Mol Biol , vol.330 , Issue.5 , pp. 1005-1014
    • Tenson, T.1    Lovmar, M.2    Ehrenberg, M.3
  • 3
    • 0023503132 scopus 로고
    • Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms
    • COI: 1:CAS:528:DyaL1cXntF2nsQ%3D%3D, PID: 2449865
    • Retsema J, Girard A, Schelkly W, et al. Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms. Antimicrob Agents Chemother. 1987;31(12):1939–47.
    • (1987) Antimicrob Agents Chemother , vol.31 , Issue.12 , pp. 1939-1947
    • Retsema, J.1    Girard, A.2    Schelkly, W.3
  • 4
    • 0026762902 scopus 로고
    • Azithromycin—spectrum of activity, pharmacokinetics, and clinical applications
    • COI: 1:STN:280:DyaK38zgt1SrsQ%3D%3D, PID: 1319048
    • Drew RH, Gallis HA. Azithromycin—spectrum of activity, pharmacokinetics, and clinical applications. Pharmacotherapy. 1992;12(3):161–73.
    • (1992) Pharmacotherapy , vol.12 , Issue.3 , pp. 161-173
    • Drew, R.H.1    Gallis, H.A.2
  • 5
    • 0026460371 scopus 로고
    • Azithromycin. A review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy
    • COI: 1:CAS:528:DyaK3sXltFOgsg%3D%3D, PID: 1280567
    • Peters DH, Friedel HA, McTavish D. Azithromycin. A review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy. Drugs. 1992;44(5):750–99.
    • (1992) Drugs , vol.44 , Issue.5 , pp. 750-799
    • Peters, D.H.1    Friedel, H.A.2    McTavish, D.3
  • 6
    • 84907050377 scopus 로고    scopus 로고
    • The wobbly status of ketolides: where do we stand?
    • COI: 1:CAS:528:DC%2BC2cXhsFWhu77K, PID: 25154307
    • Georgopapadakou NH. The wobbly status of ketolides: where do we stand? Expert Opin Investig Drugs. 2014;23(10):1313–9. doi:10.1517/13543784.2014.954036.
    • (2014) Expert Opin Investig Drugs , vol.23 , Issue.10 , pp. 1313-1319
    • Georgopapadakou, N.H.1
  • 7
    • 34247192001 scopus 로고    scopus 로고
    • The FDA, and the case of Ketek
    • COI: 1:CAS:528:DC%2BD2sXksFCgtb4%3D, PID: 17442902
    • Ross DB. The FDA, and the case of Ketek. N Engl J Med. 2007;356(16):1601–4.
    • (2007) N Engl J Med , vol.356 , Issue.16 , pp. 1601-1604
    • Ross, D.B.1
  • 8
    • 84863115207 scopus 로고    scopus 로고
    • Changing trends in antimicrobial resistance and serotypes of Streptococcus pneumoniae isolates in Asian countries: an Asian Network for Surveillance of Resistant Pathogens (ANSORP) study
    • COI: 1:CAS:528:DC%2BC38XjsVKlsbc%3D, PID: 22232285
    • Kim SH, Song JH, Chung DR, et al. Changing trends in antimicrobial resistance and serotypes of Streptococcus pneumoniae isolates in Asian countries: an Asian Network for Surveillance of Resistant Pathogens (ANSORP) study. Antimicrob Agents Chemother. 2012;56(3):1418–26. doi:10.1128/AAC.05658-11.
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.3 , pp. 1418-1426
    • Kim, S.H.1    Song, J.H.2    Chung, D.R.3
  • 9
    • 21844459488 scopus 로고    scopus 로고
    • Antimicrobial resistance among Streptococcus pneumoniae in the United States: have we begun to turn the corner on resistance to certain antimicrobial classes?
    • COI: 1:CAS:528:DC%2BD2MXmvVylsbc%3D, PID: 15983908
    • Doern GV, Richter SS, Miller A, et al. Antimicrobial resistance among Streptococcus pneumoniae in the United States: have we begun to turn the corner on resistance to certain antimicrobial classes? Clin Infect Dis. 2005;41(2):139–48.
    • (2005) Clin Infect Dis , vol.41 , Issue.2 , pp. 139-148
    • Doern, G.V.1    Richter, S.S.2    Miller, A.3
  • 10
    • 84865210377 scopus 로고    scopus 로고
    • AWARE ceftaroline surveillance program (2008–2010): trends in resistance patterns among Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States
    • COI: 1:CAS:528:DC%2BC38Xht1GjtLnK, PID: 22903951
    • Pfaller MA, Farrell DJ, Sader HS, Jones RN. AWARE ceftaroline surveillance program (2008–2010): trends in resistance patterns among Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States. Clin Infect Dis. 2012;55 Suppl 3:S187–93. doi:10.1093/cid/cis561.
    • (2012) Clin Infect Dis , vol.55 , pp. S187-S193
    • Pfaller, M.A.1    Farrell, D.J.2    Sader, H.S.3    Jones, R.N.4
  • 11
    • 84886893230 scopus 로고    scopus 로고
    • Comparison of pathogens and their antimicrobial resistance patterns in paediatric, adult and elderly patients in Canadian hospitals
    • COI: 1:CAS:528:DC%2BC3sXlvFWjsr8%3D, PID: 23587776
    • Adam HJ, Baxter MR, Davidson RJ, et al. Comparison of pathogens and their antimicrobial resistance patterns in paediatric, adult and elderly patients in Canadian hospitals. J Antimicrob Chemother. 2013;68 Suppl 1:i31–7. doi:10.1093/jac/dkt024.
    • (2013) J Antimicrob Chemother , vol.68 , pp. i31-i37
    • Adam, H.J.1    Baxter, M.R.2    Davidson, R.J.3
  • 12
    • 66149117796 scopus 로고    scopus 로고
    • Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China
    • COI: 1:CAS:528:DC%2BD1MXlvVGnsrY%3D, PID: 19273684
    • Liu Y, Ye X, Zhang H, et al. Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China. Antimicrob Agents Chemother. 2009;53(5):2160–2. doi:10.1128/AAC.01684-08.
    • (2009) Antimicrob Agents Chemother , vol.53 , Issue.5 , pp. 2160-2162
    • Liu, Y.1    Ye, X.2    Zhang, H.3
  • 13
    • 84919498931 scopus 로고    scopus 로고
    • Investigations of mycoplasma pneumoniae infections in the United States: trends in molecular typing and macrolide resistance from 2006 to 2013
    • PID: 25355769
    • Diaz MH, Benitez AJ, Winchell JM. Investigations of mycoplasma pneumoniae infections in the United States: trends in molecular typing and macrolide resistance from 2006 to 2013. J Clin Microbiol. 2015;53(1):124–30. doi:10.1128/JCM.02597-14.
    • (2015) J Clin Microbiol , vol.53 , Issue.1 , pp. 124-130
    • Diaz, M.H.1    Benitez, A.J.2    Winchell, J.M.3
  • 14
    • 17644366524 scopus 로고    scopus 로고
    • Toronto Invasive Bacterial Disease Network. Predicting antimicrobial resistance in invasive pneumococcal infections
    • COI: 1:CAS:528:DC%2BD2MXktlajsr8%3D, PID: 15825031
    • Vanderkooi OG, Low DE, Green K, Powis JE, McGeer A. Toronto Invasive Bacterial Disease Network. Predicting antimicrobial resistance in invasive pneumococcal infections. Clin Infect Dis. 2005;40(9):1288–97.
    • (2005) Clin Infect Dis , vol.40 , Issue.9 , pp. 1288-1297
    • Vanderkooi, O.G.1    Low, D.E.2    Green, K.3    Powis, J.E.4    McGeer, A.5
  • 15
    • 84930424264 scopus 로고    scopus 로고
    • The effect of macrolide resistance on the presentation and outcome of patients hospitalized for Streptococcus pneumoniae pneumonia
    • COI: 1:CAS:528:DC%2BC2MXhsVCgsb%2FI, PID: 25807239
    • Cilloniz C, Albert RK, Liapikou A, et al. The effect of macrolide resistance on the presentation and outcome of patients hospitalized for Streptococcus pneumoniae pneumonia. Am J Respir Crit Care Med. 2015;191(11):1265–72. doi:10.1164/rccm.201502-0212OC.
    • (2015) Am J Respir Crit Care Med , vol.191 , Issue.11 , pp. 1265-1272
    • Cilloniz, C.1    Albert, R.K.2    Liapikou, A.3
  • 16
    • 0035904366 scopus 로고    scopus 로고
    • Macrolide resistance among invasive Streptococcus pneumoniae isolates
    • COI: 1:CAS:528:DC%2BD3MXns1yjur0%3D, PID: 11597287
    • Hyde TB, Gay K, Stephens DS, et al. Macrolide resistance among invasive Streptococcus pneumoniae isolates. JAMA. 2001;286(15):1857–62.
    • (2001) JAMA , vol.286 , Issue.15 , pp. 1857-1862
    • Hyde, T.B.1    Gay, K.2    Stephens, D.S.3
  • 17
    • 77951092006 scopus 로고    scopus 로고
    • Streptococcus pneumoniae: epidemiology and risk factors, evolution of antimicrobial resistance, and impact of vaccines
    • PID: 20375783
    • Lynch 3rd JP, Zhanel GG. Streptococcus pneumoniae: epidemiology and risk factors, evolution of antimicrobial resistance, and impact of vaccines. Curr Opin Pulm Med. 2010;16(3):217–25. doi:10.1097/MCP.0b013e3283385653.
    • (2010) Curr Opin Pulm Med , vol.16 , Issue.3 , pp. 217-225
    • Lynch, J.P.1    Zhanel, G.G.2
  • 18
    • 0028969613 scopus 로고
    • Transmission of multidrug-resistant serotype 23F streptococcus pneumoniae in group day care: evidence suggesting capsular transformation of the resistant strain in vivo
    • COI: 1:STN:280:DyaK2M3itF2qtA%3D%3D, PID: 7706816
    • Barnes DM, Whittier S, Gilligan PH, Soares S, Tomasz A, Henderson FW. Transmission of multidrug-resistant serotype 23F streptococcus pneumoniae in group day care: evidence suggesting capsular transformation of the resistant strain in vivo. J Infect Dis. 1995;171(4):890–6.
    • (1995) J Infect Dis , vol.171 , Issue.4 , pp. 890-896
    • Barnes, D.M.1    Whittier, S.2    Gilligan, P.H.3    Soares, S.4    Tomasz, A.5    Henderson, F.W.6
  • 19
    • 0028961821 scopus 로고
    • High incidence of resistance to multiple antimicrobials in clinical isolates of Streptococcus pneumoniae from a university hospital in Korea
    • COI: 1:STN:280:DyaK2MzhsFersQ%3D%3D, PID: 7795081
    • Lee HJ, Park JY, Jang SH, Kim JH, Kim EC, Choi KW. High incidence of resistance to multiple antimicrobials in clinical isolates of Streptococcus pneumoniae from a university hospital in Korea. Clin Infect Dis. 1995;20(4):826–35.
    • (1995) Clin Infect Dis , vol.20 , Issue.4 , pp. 826-835
    • Lee, H.J.1    Park, J.Y.2    Jang, S.H.3    Kim, J.H.4    Kim, E.C.5    Choi, K.W.6
  • 20
    • 33847155159 scopus 로고    scopus 로고
    • Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults
    • COI: 1:CAS:528:DC%2BD2sXjtVWrs74%3D, PID: 17278083
    • Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults. Clin Infect Dis. 2007;44 Suppl 2:S27–72. doi:10.1086/511159.
    • (2007) Clin Infect Dis , vol.44 , pp. S27-S72
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3
  • 21
    • 0038556829 scopus 로고    scopus 로고
    • Streptococcus pneumoniae bacteremia: duration of previous antibiotic use and association with penicillin resistance
    • PID: 12715307
    • Ruhe JJ, Hasbun R. Streptococcus pneumoniae bacteremia: duration of previous antibiotic use and association with penicillin resistance. Clin Infect Dis. 2003;36(9):1132–8.
    • (2003) Clin Infect Dis , vol.36 , Issue.9 , pp. 1132-1138
    • Ruhe, J.J.1    Hasbun, R.2
  • 22
    • 0002226377 scopus 로고    scopus 로고
    • Macrolides: structures and microbial targets
    • COI: 1:CAS:528:DC%2BD3MXntVWrsL0%3D, PID: 11574188
    • Retsema J, Fu W. Macrolides: structures and microbial targets. Int J Antimicrob Agents. 2001;18 Suppl 1:S3–10.
    • (2001) Int J Antimicrob Agents , vol.18 , pp. S3-S10
    • Retsema, J.1    Fu, W.2
  • 23
    • 0029849428 scopus 로고    scopus 로고
    • Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system
    • COI: 1:CAS:528:DyaK28Xks12qsrw%3D, PID: 8843287
    • Sutcliffe J, Tait-Kamradt A, Wondrack L. Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. Antimicrob Agents Chemother. 1996;40(8):1817–24.
    • (1996) Antimicrob Agents Chemother , vol.40 , Issue.8 , pp. 1817-1824
    • Sutcliffe, J.1    Tait-Kamradt, A.2    Wondrack, L.3
  • 24
    • 19344372246 scopus 로고    scopus 로고
    • Emergence and spread of streptococcus pneumoniae with erm(B) and mef(A) resistance
    • COI: 1:CAS:528:DC%2BD2MXlsFSit7Y%3D, PID: 15963279
    • Farrell DJ, Jenkins SG, Brown SD, Patel M, Lavin BS, Klugman KP. Emergence and spread of streptococcus pneumoniae with erm(B) and mef(A) resistance. Emerg Infect Dis. 2005;11(6):851–8. doi:10.3201/eid1106.050222.
    • (2005) Emerg Infect Dis , vol.11 , Issue.6 , pp. 851-858
    • Farrell, D.J.1    Jenkins, S.G.2    Brown, S.D.3    Patel, M.4    Lavin, B.S.5    Klugman, K.P.6
  • 25
    • 84863710809 scopus 로고    scopus 로고
    • Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases
    • COI: 1:CAS:528:DC%2BC38XmtFaqsrw%3D, PID: 22105373
    • Zarogoulidis P, Papanas N, Kioumis I, Chatzaki E, Maltezos E, Zarogoulidis K. Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases. Eur J Clin Pharmacol. 2012;68(5):479–503. doi:10.1007/s00228-011-1161-x.
    • (2012) Eur J Clin Pharmacol , vol.68 , Issue.5 , pp. 479-503
    • Zarogoulidis, P.1    Papanas, N.2    Kioumis, I.3    Chatzaki, E.4    Maltezos, E.5    Zarogoulidis, K.6
  • 26
    • 0038143318 scopus 로고    scopus 로고
    • Long-term efficacy and safety of clarithromycin treatment in patients with diffuse panbronchiolitis
    • COI: 1:STN:280:DC%2BD3szisVynsA%3D%3D, PID: 12854636
    • Kadota J, Mukae H, Ishii H, et al. Long-term efficacy and safety of clarithromycin treatment in patients with diffuse panbronchiolitis. Respir Med. 2003;97(7):844–50.
    • (2003) Respir Med , vol.97 , Issue.7 , pp. 844-850
    • Kadota, J.1    Mukae, H.2    Ishii, H.3
  • 27
    • 0036156534 scopus 로고    scopus 로고
    • Therapy with macrolides in patients with cystic fibrosis
    • COI: 1:CAS:528:DC%2BD38XhsVOisrw%3D, PID: 11837560
    • Gaylor AS, Reilly JC. Therapy with macrolides in patients with cystic fibrosis. Pharmacotherapy. 2002;22(2):227–39.
    • (2002) Pharmacotherapy , vol.22 , Issue.2 , pp. 227-239
    • Gaylor, A.S.1    Reilly, J.C.2
  • 28
    • 84906936060 scopus 로고    scopus 로고
    • Prolonged treatment with macrolides in adult patients with non-cystic fibrosis bronchiectasis: meta-analysis of randomized controlled trials
    • COI: 1:CAS:528:DC%2BC2cXks1Ortrw%3D, PID: 24594263
    • Zhuo GY, He Q, Xiang-Lian L, Ya-Nan Y, Si-Te F. Prolonged treatment with macrolides in adult patients with non-cystic fibrosis bronchiectasis: meta-analysis of randomized controlled trials. Pulm Pharmacol Ther. 2014;29(1):80–8. doi:10.1016/j.pupt.2014.02.002.
    • (2014) Pulm Pharmacol Ther , vol.29 , Issue.1 , pp. 80-88
    • Zhuo, G.Y.1    He, Q.2    Xiang-Lian, L.3    Ya-Nan, Y.4    Si-Te, F.5
  • 29
    • 38148998845 scopus 로고    scopus 로고
    • Long-term azithromycin for bronchiolitis obliterans syndrome after lung transplantation
    • COI: 1:CAS:528:DC%2BD1cXlvVKntw%3D%3D, PID: 18192909
    • Gottlieb J, Szangolies J, Koehnlein T, Golpon H, Simon A, Welte T. Long-term azithromycin for bronchiolitis obliterans syndrome after lung transplantation. Transplantation. 2008;85(1):36–41. doi:10.1097/01.tp.0000295981.84633.bc.
    • (2008) Transplantation , vol.85 , Issue.1 , pp. 36-41
    • Gottlieb, J.1    Szangolies, J.2    Koehnlein, T.3    Golpon, H.4    Simon, A.5    Welte, T.6
  • 30
    • 84875219719 scopus 로고    scopus 로고
    • Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial
    • PID: 23291349
    • Brusselle GG, Vanderstichele C, Jordens P, et al. Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial. Thorax. 2013;68(4):322–9. doi:10.1136/thoraxjnl-2012-202698.
    • (2013) Thorax , vol.68 , Issue.4 , pp. 322-329
    • Brusselle, G.G.1    Vanderstichele, C.2    Jordens, P.3
  • 31
    • 84926381750 scopus 로고    scopus 로고
    • Prophylactic use of macrolide antibiotics for the prevention of chronic obstructive pulmonary disease exacerbation: a meta-analysis
    • PID: 25812085
    • Ni W, Shao X, Cai X, et al. Prophylactic use of macrolide antibiotics for the prevention of chronic obstructive pulmonary disease exacerbation: a meta-analysis. PLoS One. 2015;10(3):e0121257. doi:10.1371/journal.pone.0121257.
    • (2015) PLoS One , vol.10 , Issue.3 , pp. e0121257
    • Ni, W.1    Shao, X.2    Cai, X.3
  • 32
    • 0033760736 scopus 로고    scopus 로고
    • Macrolide antibiotics as biological response modifiers
    • COI: 1:CAS:528:DC%2BD3cXnvVCisLw%3D, PID: 11249569
    • Rubin BK, Tamaoki J. Macrolide antibiotics as biological response modifiers. Curr Opin Investig Drugs. 2000;1(2):169–72.
    • (2000) Curr Opin Investig Drugs , vol.1 , Issue.2 , pp. 169-172
    • Rubin, B.K.1    Tamaoki, J.2
  • 33
    • 0030722060 scopus 로고    scopus 로고
    • Inhibitory effect of macrolides on interleukin-8 secretion from cultured human nasal epithelial cells
    • COI: 1:CAS:528:DyaK2sXotVKhu7Y%3D, PID: 9396683
    • Suzuki H, Shimomura A, Ikeda K, Furukawa M, Oshima T, Takasaka T. Inhibitory effect of macrolides on interleukin-8 secretion from cultured human nasal epithelial cells. Laryngoscope. 1997;107(12 Pt 1):1661–6.
    • (1997) Laryngoscope , vol.107 , pp. 1661-1666
    • Suzuki, H.1    Shimomura, A.2    Ikeda, K.3    Furukawa, M.4    Oshima, T.5    Takasaka, T.6
  • 34
    • 0028886393 scopus 로고
    • Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells
    • COI: 1:CAS:528:DyaK2MXpslWrsrk%3D, PID: 8575568
    • Khair OA, Devalia JL, Abdelaziz MM, Sapsford RJ, Davies RJ. Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells. Eur Respir J. 1995;8(9):1451–7.
    • (1995) Eur Respir J , vol.8 , Issue.9 , pp. 1451-1457
    • Khair, O.A.1    Devalia, J.L.2    Abdelaziz, M.M.3    Sapsford, R.J.4    Davies, R.J.5
  • 35
    • 0030471653 scopus 로고    scopus 로고
    • Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils
    • COI: 1:CAS:528:DyaK2sXlvFOjsw%3D%3D, PID: 8979156
    • Anderson R, Theron AJ, Feldman C. Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils. Inflammation. 1996;20(6):693–705.
    • (1996) Inflammation , vol.20 , Issue.6 , pp. 693-705
    • Anderson, R.1    Theron, A.J.2    Feldman, C.3
  • 36
    • 2142700049 scopus 로고    scopus 로고
    • Molecular mechanisms of anti-inflammatory action of erythromycin in human bronchial epithelial cells: possible role in the signaling pathway that regulates nuclear factor-kappaB activation
    • COI: 1:CAS:528:DC%2BD2cXjslClsbc%3D, PID: 15105108
    • Desaki M, Okazaki H, Sunazuka T, Omura S, Yamamoto K, Takizawa H. Molecular mechanisms of anti-inflammatory action of erythromycin in human bronchial epithelial cells: possible role in the signaling pathway that regulates nuclear factor-kappaB activation. Antimicrob Agents Chemother. 2004;48(5):1581–5.
    • (2004) Antimicrob Agents Chemother , vol.48 , Issue.5 , pp. 1581-1585
    • Desaki, M.1    Okazaki, H.2    Sunazuka, T.3    Omura, S.4    Yamamoto, K.5    Takizawa, H.6
  • 37
    • 0028903792 scopus 로고
    • Erythromycin shortens neutrophil survival by accelerating apoptosis
    • COI: 1:CAS:528:DyaK2MXkvVKnurY%3D, PID: 7785987
    • Aoshiba K, Nagai A, Konno K. Erythromycin shortens neutrophil survival by accelerating apoptosis. Antimicrob Agents Chemother. 1995;39(4):872–7.
    • (1995) Antimicrob Agents Chemother , vol.39 , Issue.4 , pp. 872-877
    • Aoshiba, K.1    Nagai, A.2    Konno, K.3
  • 38
    • 0041874952 scopus 로고    scopus 로고
    • In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells
    • PID: 12829454
    • Shimizu T, Shimizu S, Hattori R, Gabazza EC, Majima Y. In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells. Am J Respir Crit Care Med. 2003;168(5):581–7. doi:10.1164/rccm.200212-1437OC.
    • (2003) Am J Respir Crit Care Med , vol.168 , Issue.5 , pp. 581-587
    • Shimizu, T.1    Shimizu, S.2    Hattori, R.3    Gabazza, E.C.4    Majima, Y.5
  • 39
    • 39549115019 scopus 로고    scopus 로고
    • Macrolide antibiotics as immunomodulatory medications: proposed mechanisms of action
    • COI: 1:CAS:528:DC%2BD1cXisVWitLw%3D, PID: 18289694
    • Shinkai M, Henke MO, Rubin BK. Macrolide antibiotics as immunomodulatory medications: proposed mechanisms of action. Pharmacol Ther. 2008;117(3):393–405. doi:10.1016/j.pharmthera.2007.11.001.
    • (2008) Pharmacol Ther , vol.117 , Issue.3 , pp. 393-405
    • Shinkai, M.1    Henke, M.O.2    Rubin, B.K.3
  • 40
    • 42549119145 scopus 로고    scopus 로고
    • Effect of clarithromycin in patients with sepsis and ventilator-associated pneumonia
    • COI: 1:CAS:528:DC%2BD1cXlsVCjsrc%3D, PID: 18444850
    • Giamarellos-Bourboulis EJ, Pechere JC, Routsi C, et al. Effect of clarithromycin in patients with sepsis and ventilator-associated pneumonia. Clin Infect Dis. 2008;46(8):1157–64. doi:10.1086/529439.
    • (2008) Clin Infect Dis , vol.46 , Issue.8 , pp. 1157-1164
    • Giamarellos-Bourboulis, E.J.1    Pechere, J.C.2    Routsi, C.3
  • 41
    • 84862557241 scopus 로고    scopus 로고
    • Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis caused by gram-negative bacteria: results from a randomized clinical study
    • COI: 1:CAS:528:DC%2BC38XpsV2isb0%3D, PID: 22564837
    • Spyridaki A, Raftogiannis M, Antonopoulou A, et al. Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis caused by gram-negative bacteria: results from a randomized clinical study. Antimicrob Agents Chemother. 2012;56(7):3819–25.
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.7 , pp. 3819-3825
    • Spyridaki, A.1    Raftogiannis, M.2    Antonopoulou, A.3
  • 42
    • 84884209745 scopus 로고    scopus 로고
    • Serotype prevalence and antibiotic resistance in Streptococcus pneumoniae clinical isolates among global populations
    • COI: 1:CAS:528:DC%2BC3sXhtlahu7rM, PID: 23928466
    • Hackel M, Lascols C, Bouchillon S, Hilton B, Morgenstern D, Purdy J. Serotype prevalence and antibiotic resistance in Streptococcus pneumoniae clinical isolates among global populations. Vaccine. 2013;31(42):4881–7. doi:10.1016/j.vaccine.2013.07.054.
    • (2013) Vaccine , vol.31 , Issue.42 , pp. 4881-4887
    • Hackel, M.1    Lascols, C.2    Bouchillon, S.3    Hilton, B.4    Morgenstern, D.5    Purdy, J.6
  • 44
    • 84875513038 scopus 로고    scopus 로고
    • Macrolides vs. quinolones for community-acquired pneumonia: meta-analysis of randomized controlled trials
    • COI: 1:CAS:528:DC%2BC3sXkt1GgsLo%3D, PID: 22489673
    • Skalsky K, Yahav D, Lador A, Eliakim-Raz N, Leibovici L, Paul M. Macrolides vs. quinolones for community-acquired pneumonia: meta-analysis of randomized controlled trials. Clin Microbiol Infect. 2013;19(4):370–8.
    • (2013) Clin Microbiol Infect , vol.19 , Issue.4 , pp. 370-378
    • Skalsky, K.1    Yahav, D.2    Lador, A.3    Eliakim-Raz, N.4    Leibovici, L.5    Paul, M.6
  • 46
    • 84936960165 scopus 로고    scopus 로고
    • Azithromycin for acute lower respiratory tract infections
    • PID: 25749735
    • Laopaiboon M, Panpanich R, Swa Mya K. Azithromycin for acute lower respiratory tract infections. Cochrane Database Syst Rev. 2015;3:CD001954. doi:10.1002/14651858.CD001954.pub4.
    • (2015) Cochrane Database Syst Rev , vol.3 , pp. CD001954
    • Laopaiboon, M.1    Panpanich, R.2    Swa Mya, K.3
  • 47
    • 0034110061 scopus 로고    scopus 로고
    • Infectious etiology of acute exacerbations of chronic bronchitis
    • COI: 1:STN:280:DC%2BD3czgsFCntQ%3D%3D, PID: 10843981
    • Sethi S. Infectious etiology of acute exacerbations of chronic bronchitis. Chest. 2000;117(5 Suppl 2):380S–5.
    • (2000) Chest , vol.117 , pp. 380S-385
    • Sethi, S.1
  • 48
    • 0025170510 scopus 로고
    • Acute bronchitis in the community: clinical features, infective factors, changes in pulmonary function and bronchial reactivity to histamine
    • COI: 1:STN:280:DyaK3M%2Fmt1Knsg%3D%3D, PID: 2174179
    • Boldy DA, Skidmore SJ, Ayres JG. Acute bronchitis in the community: clinical features, infective factors, changes in pulmonary function and bronchial reactivity to histamine. Respir Med. 1990;84(5):377–85.
    • (1990) Respir Med , vol.84 , Issue.5 , pp. 377-385
    • Boldy, D.A.1    Skidmore, S.J.2    Ayres, J.G.3
  • 49
    • 0035004522 scopus 로고    scopus 로고
    • Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background
    • COI: 1:STN:280:DC%2BD3MzhtFGisg%3D%3D, PID: 11385346
    • Gonzales R, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background. Ann Emerg Med. 2001;37(6):720–7.
    • (2001) Ann Emerg Med , vol.37 , Issue.6 , pp. 720-727
    • Gonzales, R.1    Bartlett, J.G.2    Besser, R.E.3
  • 50
    • 0036499021 scopus 로고    scopus 로고
    • Clinical relevance of macrolide-resistant Streptococcus pneumoniae for community-acquired pneumonia
    • Lynch III JP, Martinez FJ. Clinical relevance of macrolide-resistant Streptococcus pneumoniae for community-acquired pneumonia. Clin Infect Dis. 2002;34 Suppl 1:S27–46.
    • (2002) Clin Infect Dis , vol.34 , pp. S27-S46
    • Lynch, J.P.1    Martinez, F.J.2
  • 51
    • 0033596083 scopus 로고    scopus 로고
    • Associations between initial antimicrobial therapy and medical outcomes for hospitalized elderly patients with pneumonia
    • COI: 1:STN:280:DC%2BD3c%2FjslKksg%3D%3D, PID: 10573046
    • Gleason PP, Meehan TP, Fine JM, Galusha DH, Fine MJ. Associations between initial antimicrobial therapy and medical outcomes for hospitalized elderly patients with pneumonia. Arch Intern Med. 1999;159(21):2562–72.
    • (1999) Arch Intern Med , vol.159 , Issue.21 , pp. 2562-2572
    • Gleason, P.P.1    Meehan, T.P.2    Fine, J.M.3    Galusha, D.H.4    Fine, M.J.5
  • 52
    • 0034939765 scopus 로고    scopus 로고
    • Empiric antibiotic therapy and mortality among medicare pneumonia inpatients in 10 western states: 1993, 1995, and 1997
    • COI: 1:STN:280:DC%2BD3MvhtVGmtA%3D%3D, PID: 11348948
    • Houck PM, MacLehose RF, Niederman MS, Lowery JK. Empiric antibiotic therapy and mortality among medicare pneumonia inpatients in 10 western states: 1993, 1995, and 1997. Chest. 2001;119(5):1420–6.
    • (2001) Chest , vol.119 , Issue.5 , pp. 1420-1426
    • Houck, P.M.1    MacLehose, R.F.2    Niederman, M.S.3    Lowery, J.K.4
  • 53
    • 0034039673 scopus 로고    scopus 로고
    • Antimicrobial selection for hospitalized patients with presumed community-acquired pneumonia: a survey of nonteaching US community hospitals
    • COI: 1:STN:280:DC%2BD3c3jtlersA%3D%3D, PID: 10772428
    • Dudas V, Hopefl A, Jacobs R, Guglielmo BJ. Antimicrobial selection for hospitalized patients with presumed community-acquired pneumonia: a survey of nonteaching US community hospitals. Ann Pharmacother. 2000;34(4):446–52.
    • (2000) Ann Pharmacother , vol.34 , Issue.4 , pp. 446-452
    • Dudas, V.1    Hopefl, A.2    Jacobs, R.3    Guglielmo, B.J.4
  • 54
    • 0037541094 scopus 로고    scopus 로고
    • Impact of initial antibiotic choice on clinical outcomes in community-acquired pneumonia: analysis of a hospital claims-made database
    • PID: 12740267
    • Brown RB, Iannini P, Gross P, Kunkel M. Impact of initial antibiotic choice on clinical outcomes in community-acquired pneumonia: analysis of a hospital claims-made database. Chest. 2003;123(5):1503–11.
    • (2003) Chest , vol.123 , Issue.5 , pp. 1503-1511
    • Brown, R.B.1    Iannini, P.2    Gross, P.3    Kunkel, M.4
  • 55
    • 80053284682 scopus 로고    scopus 로고
    • Guidelines for the management of adult lower respiratory tract infections—full version
    • PID: 21951385
    • Woodhead M, Blasi F, Ewig S, et al. Guidelines for the management of adult lower respiratory tract infections—full version. Clin Microbiol Infect. 2011;17 Suppl 6:E1–59. doi:10.1111/j.1469-0691.2011.03672.x.
    • (2011) Clin Microbiol Infect , vol.17 , pp. E1-E59
    • Woodhead, M.1    Blasi, F.2    Ewig, S.3
  • 56
    • 21844477598 scopus 로고    scopus 로고
    • Empiric antibiotic coverage of atypical pathogens for community acquired pneumonia in hospitalized adults
    • PID: 15846713
    • Shefet D, Robenshtock E, Paul M, Leibovici L. Empiric antibiotic coverage of atypical pathogens for community acquired pneumonia in hospitalized adults. Cochrane Database Syst Rev. 2005;2(2):CD004418. doi:10.1002/14651858.CD004418.pub2.
    • (2005) Cochrane Database Syst Rev , vol.2 , Issue.2 , pp. CD004418
    • Shefet, D.1    Robenshtock, E.2    Paul, M.3    Leibovici, L.4
  • 57
    • 14644394235 scopus 로고    scopus 로고
    • Effectiveness of beta lactam antibiotics compared with antibiotics active against atypical pathogens in non-severe community acquired pneumonia: meta-analysis
    • COI: 1:CAS:528:DC%2BD2MXislahsbw%3D, PID: 15684024
    • Mills GD, Oehley MR, Arrol B. Effectiveness of beta lactam antibiotics compared with antibiotics active against atypical pathogens in non-severe community acquired pneumonia: meta-analysis. BMJ. 2005;330(7489):456.
    • (2005) BMJ , vol.330 , Issue.7489 , pp. 456
    • Mills, G.D.1    Oehley, M.R.2    Arrol, B.3
  • 58
    • 84873036547 scopus 로고    scopus 로고
    • Empiric antibiotic coverage of atypical pathogens for community-acquired pneumonia in hospitalized adults
    • Eliakim-Raz N, Robenshtok E, Shefet D, et al. Empiric antibiotic coverage of atypical pathogens for community-acquired pneumonia in hospitalized adults. Cochrane Database Syst Rev. 2012;9:004418.
    • (2012) Cochrane Database Syst Rev , vol.9 , pp. 004418
    • Eliakim-Raz, N.1    Robenshtok, E.2    Shefet, D.3
  • 59
    • 84903904746 scopus 로고    scopus 로고
    • Beta-lactam/macrolide dual therapy versus beta-lactam monotherapy for the treatment of community-acquired pneumonia in adults: a systematic review and meta-analysis
    • COI: 1:CAS:528:DC%2BC2cXotFCqsbs%3D, PID: 24535276
    • Nie W, Li B, Xiu Q. Beta-lactam/macrolide dual therapy versus beta-lactam monotherapy for the treatment of community-acquired pneumonia in adults: a systematic review and meta-analysis. J Antimicrob Chemother. 2014;69(6):1441–6.
    • (2014) J Antimicrob Chemother , vol.69 , Issue.6 , pp. 1441-1446
    • Nie, W.1    Li, B.2    Xiu, Q.3
  • 60
    • 84926321601 scopus 로고    scopus 로고
    • Antibiotic treatment strategies for community-acquired pneumonia in adults
    • COI: 1:CAS:528:DC%2BC2MXns1Wqu78%3D, PID: 25830421
    • Postma DF, van Werkhoven CH, van Elden LJ, et al. Antibiotic treatment strategies for community-acquired pneumonia in adults. N Engl J Med. 2015;372(14):1312–23.
    • (2015) N Engl J Med , vol.372 , Issue.14 , pp. 1312-1323
    • Postma, D.F.1    van Werkhoven, C.H.2    van Elden, L.J.3
  • 61
    • 84919486371 scopus 로고    scopus 로고
    • Beta-lactam monotherapy vs beta-lactam-macrolide combination treatment in moderately severe community-acquired pneumonia: a randomized noninferiority trial
    • PID: 25286173
    • Garin N, Genne D, Carballo S, et al. Beta-lactam monotherapy vs beta-lactam-macrolide combination treatment in moderately severe community-acquired pneumonia: a randomized noninferiority trial. JAMA Intern Med. 2014;174(12):1894–901.
    • (2014) JAMA Intern Med , vol.174 , Issue.12 , pp. 1894-1901
    • Garin, N.1    Genne, D.2    Carballo, S.3
  • 62
    • 84874315562 scopus 로고    scopus 로고
    • Impact of guideline-concordant antibiotics and macrolide/beta-lactam combinations in 3203 patients hospitalized with pneumonia: prospective cohort study
    • COI: 1:CAS:528:DC%2BC3sXjtlWrurc%3D, PID: 22404691
    • Asadi L, Eurich DT, Gamble JM, Minhas-Sandhu JK, Marrie TJ, Majumdar SR. Impact of guideline-concordant antibiotics and macrolide/beta-lactam combinations in 3203 patients hospitalized with pneumonia: prospective cohort study. Clin Microbiol Infect. 2013;19(3):257–64.
    • (2013) Clin Microbiol Infect , vol.19 , Issue.3 , pp. 257-264
    • Asadi, L.1    Eurich, D.T.2    Gamble, J.M.3    Minhas-Sandhu, J.K.4    Marrie, T.J.5    Majumdar, S.R.6
  • 63
    • 84863933351 scopus 로고    scopus 로고
    • Macrolide-based regimens and mortality in hospitalized patients with community-acquired pneumonia: a systematic review and meta-analysis
    • COI: 1:CAS:528:DC%2BC38XhtVejurbI, PID: 22511553
    • Asadi L, Sligl WI, Eurich DT, et al. Macrolide-based regimens and mortality in hospitalized patients with community-acquired pneumonia: a systematic review and meta-analysis. Clin Infect Dis. 2012;55(3):371–80.
    • (2012) Clin Infect Dis , vol.55 , Issue.3 , pp. 371-380
    • Asadi, L.1    Sligl, W.I.2    Eurich, D.T.3
  • 64
    • 0033925423 scopus 로고    scopus 로고
    • Antimicrobial treatment failures in patients with community-acquired pneumonia: causes and prognostic implications
    • COI: 1:STN:280:DC%2BD3cvisFekug%3D%3D, PID: 10903235
    • Arancibia F, Ewig S, Martinez JA, et al. Antimicrobial treatment failures in patients with community-acquired pneumonia: causes and prognostic implications. Am J Respir Crit Care Med. 2000;162(1):154–60. doi:10.1164/ajrccm.162.1.9907023.
    • (2000) Am J Respir Crit Care Med , vol.162 , Issue.1 , pp. 154-160
    • Arancibia, F.1    Ewig, S.2    Martinez, J.A.3
  • 65
    • 1542347642 scopus 로고    scopus 로고
    • Causes and factors associated with early failure in hospitalized patients with community-acquired pneumonia
    • PID: 15006826
    • Roson B, Carratala J, Fernandez-Sabe N, Tubau F, Manresa F, Gudiol F. Causes and factors associated with early failure in hospitalized patients with community-acquired pneumonia. Arch Intern Med. 2004;164(5):502–8. doi:10.1001/archinte.164.5.502.
    • (2004) Arch Intern Med , vol.164 , Issue.5 , pp. 502-508
    • Roson, B.1    Carratala, J.2    Fernandez-Sabe, N.3    Tubau, F.4    Manresa, F.5    Gudiol, F.6
  • 66
    • 0032911760 scopus 로고    scopus 로고
    • Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients
    • COI: 1:STN:280:DyaK1M7kvFKqtg%3D%3D, PID: 10027448
    • Kollef MH, Sherman G, Ward S, Fraser VJ. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest. 1999;115(2):462–74.
    • (1999) Chest , vol.115 , Issue.2 , pp. 462-474
    • Kollef, M.H.1    Sherman, G.2    Ward, S.3    Fraser, V.J.4
  • 67
    • 84893313755 scopus 로고    scopus 로고
    • Macrolides and mortality in critically ill patients with community-acquired pneumonia: a systematic review and meta-analysis
    • COI: 1:CAS:528:DC%2BC2cXhtFyhtLc%3D, PID: 24158175
    • Sligl WI, Asadi L, Eurich DT, Tjosvold L, Marrie TJ, Majumdar SR. Macrolides and mortality in critically ill patients with community-acquired pneumonia: a systematic review and meta-analysis. Crit Care Med. 2014;42(2):420–32.
    • (2014) Crit Care Med , vol.42 , Issue.2 , pp. 420-432
    • Sligl, W.I.1    Asadi, L.2    Eurich, D.T.3    Tjosvold, L.4    Marrie, T.J.5    Majumdar, S.R.6
  • 68
    • 84887362831 scopus 로고    scopus 로고
    • Initial use of one or two antibiotics for critically ill patients with community-acquired pneumonia: impact on survival and bacterial resistance
    • PID: 24200097
    • Adrie C, Schwebel C, Garrouste-Orgeas M, et al. Initial use of one or two antibiotics for critically ill patients with community-acquired pneumonia: impact on survival and bacterial resistance. Crit Care. 2013;17(6):R265. doi:10.1186/cc13095.
    • (2013) Crit Care , vol.17 , Issue.6 , pp. R265
    • Adrie, C.1    Schwebel, C.2    Garrouste-Orgeas, M.3
  • 69
    • 77951209165 scopus 로고    scopus 로고
    • Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia
    • COI: 1:CAS:528:DC%2BC3cXjtFygsbw%3D, PID: 19953222
    • Martin-Loeches I, Lisboa T, Rodriguez A, et al. Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia. Intensive Care Med. 2010;36(4):612–20. doi:10.1007/s00134-009-1730-y.
    • (2010) Intensive Care Med , vol.36 , Issue.4 , pp. 612-620
    • Martin-Loeches, I.1    Lisboa, T.2    Rodriguez, A.3
  • 70
    • 58849166805 scopus 로고    scopus 로고
    • Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia
    • COI: 1:CAS:528:DC%2BD1MXls1eksLw%3D, PID: 18768577
    • Restrepo MI, Mortensen EM, Waterer GW, Wunderink RG, Coalson JJ, Anzueto A. Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia. Eur Respir J. 2009;33(1):153–9. doi:10.1183/09031936.00054108.
    • (2009) Eur Respir J , vol.33 , Issue.1 , pp. 153-159
    • Restrepo, M.I.1    Mortensen, E.M.2    Waterer, G.W.3    Wunderink, R.G.4    Coalson, J.J.5    Anzueto, A.6
  • 71
    • 33847173420 scopus 로고    scopus 로고
    • Antibiotics for bacteremic pneumonia: improved outcomes with macrolides but not fluoroquinolones
    • COI: 1:CAS:528:DC%2BD2sXjtlWqt7w%3D, PID: 17296649
    • Metersky ML, Ma A, Houck PM, Bratzler DW. Antibiotics for bacteremic pneumonia: improved outcomes with macrolides but not fluoroquinolones. Chest. 2007;131(2):466–73. doi:10.1378/chest.06-1426.
    • (2007) Chest , vol.131 , Issue.2 , pp. 466-473
    • Metersky, M.L.1    Ma, A.2    Houck, P.M.3    Bratzler, D.W.4
  • 72
    • 0037442372 scopus 로고    scopus 로고
    • Addition of a macrolide to a beta-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia
    • COI: 1:CAS:528:DC%2BD3sXitVGqu74%3D, PID: 12567294
    • Martinez JA, Horcajada JP, Almela M, et al. Addition of a macrolide to a beta-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia. Clin Infect Dis. 2003;36(4):389–95.
    • (2003) Clin Infect Dis , vol.36 , Issue.4 , pp. 389-395
    • Martinez, J.A.1    Horcajada, J.P.2    Almela, M.3
  • 73
    • 57349155272 scopus 로고    scopus 로고
    • Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: a meta-analysis of randomized controlled trials
    • PID: 19047608
    • Vardakas KZ, Siempos II, Grammatikos A, Athanassa Z, Korbila IP, Falagas ME. Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: a meta-analysis of randomized controlled trials. CMAJ. 2008;179(12):1269–77. doi:10.1503/cmaj.080358; 10.1503/cmaj.080358.
    • (2008) CMAJ , vol.179 , Issue.12 , pp. 1269-1277
    • Vardakas, K.Z.1    Siempos, I.I.2    Grammatikos, A.3    Athanassa, Z.4    Korbila, I.P.5    Falagas, M.E.6
  • 74
    • 0036861678 scopus 로고    scopus 로고
    • Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalized with community-acquired pneumonia: a randomized, open-label, multicenter study of clinical efficacy and tolerability
    • COI: 1:CAS:528:DC%2BD38Xpsleku7s%3D, PID: 12501883
    • Lode H, File Jr TM, Mandell L, et al. Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalized with community-acquired pneumonia: a randomized, open-label, multicenter study of clinical efficacy and tolerability. Clin Ther. 2002;24(11):1915–36.
    • (2002) Clin Ther , vol.24 , Issue.11 , pp. 1915-1936
    • Lode, H.1    File, T.M.2    Mandell, L.3
  • 75
    • 28744456644 scopus 로고    scopus 로고
    • Treatment with sequential intravenous or oral moxifloxacin was associated with faster clinical improvement than was standard therapy for hospitalized patients with community-acquired pneumonia who received initial parenteral therapy
    • MOXIRAPID Study Group COI: 1:CAS:528:DC%2BD28XitVOnuw%3D%3D, PID: 16288390
    • Welte T, Petermann W, Schurmann D, Bauer TT, Reimnitz P, MOXIRAPID Study Group. Treatment with sequential intravenous or oral moxifloxacin was associated with faster clinical improvement than was standard therapy for hospitalized patients with community-acquired pneumonia who received initial parenteral therapy. Clin Infect Dis. 2005;41(12):1697–705.
    • (2005) Clin Infect Dis , vol.41 , Issue.12 , pp. 1697-1705
    • Welte, T.1    Petermann, W.2    Schurmann, D.3    Bauer, T.T.4    Reimnitz, P.5
  • 76
    • 3042589219 scopus 로고    scopus 로고
    • Gemifloxacin once daily for 7 days compared to amoxicillin/clavulanic acid thrice daily for 10 days for the treatment of community-acquired pneumonia of suspected pneumococcal origin
    • COI: 1:STN:280:DC%2BD2czpvFOkuw%3D%3D, PID: 15303634
    • Leophonte P, File T, Feldman C. Gemifloxacin once daily for 7 days compared to amoxicillin/clavulanic acid thrice daily for 10 days for the treatment of community-acquired pneumonia of suspected pneumococcal origin. Respir Med. 2004;98(8):708–20.
    • (2004) Respir Med , vol.98 , Issue.8 , pp. 708-720
    • Leophonte, P.1    File, T.2    Feldman, C.3
  • 77
    • 34548022149 scopus 로고    scopus 로고
    • Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) study
    • COI: 1:CAS:528:DC%2BD2sXhtVSqtrvL, PID: 17698689
    • Kellum JA, Kong L, Fink MP, et al. Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) study. Arch Intern Med. 2007;167(15):1655–63.
    • (2007) Arch Intern Med , vol.167 , Issue.15 , pp. 1655-1663
    • Kellum, J.A.1    Kong, L.2    Fink, M.P.3
  • 78
    • 84856960076 scopus 로고    scopus 로고
    • Immunomodulatory effects of macrolides during community-acquired pneumonia: a literature review
    • COI: 1:CAS:528:DC%2BC38Xit1Ogtrc%3D, PID: 22190609
    • Kovaleva A, Remmelts HH, Rijkers GT, Hoepelman AI, Biesma DH, Oosterheert JJ. Immunomodulatory effects of macrolides during community-acquired pneumonia: a literature review. J Antimicrob Chemother. 2012;67(3):530–40.
    • (2012) J Antimicrob Chemother , vol.67 , Issue.3 , pp. 530-540
    • Kovaleva, A.1    Remmelts, H.H.2    Rijkers, G.T.3    Hoepelman, A.I.4    Biesma, D.H.5    Oosterheert, J.J.6
  • 79
    • 84901011433 scopus 로고    scopus 로고
    • Macrolide antibiotics and the risk of cardiac arrhythmias
    • COI: 1:CAS:528:DC%2BC2cXhtFSns7fO, PID: 24707986
    • Albert RK, Schuller JL, Clinical Research Network COPD. Macrolide antibiotics and the risk of cardiac arrhythmias. Am J Respir Crit Care Med. 2014;189(10):1173–80. doi:10.1164/rccm.201402-0385CI.
    • (2014) Am J Respir Crit Care Med , vol.189 , Issue.10 , pp. 1173-1180
    • Albert, R.K.1    Schuller, J.L.2    Clinical Research Network, C.O.P.D.3
  • 80
    • 84892495535 scopus 로고    scopus 로고
    • Antibiotic-induced cardiac arrhythmias
    • COI: 1:CAS:528:DC%2BC2cXhtVKkurk%3D, PID: 24428853
    • Abo-Salem E, Fowler JC, Attari M, et al. Antibiotic-induced cardiac arrhythmias. Cardiovasc Ther. 2014;32(1):19–25. doi:10.1111/1755-5922.12054.
    • (2014) Cardiovasc Ther , vol.32 , Issue.1 , pp. 19-25
    • Abo-Salem, E.1    Fowler, J.C.2    Attari, M.3
  • 81
    • 33845512496 scopus 로고    scopus 로고
    • Antimicrobial-associated QT interval prolongation: pointes of interest
    • COI: 1:CAS:528:DC%2BD2sXislWjsw%3D%3D, PID: 17109296
    • Owens Jr RC, Nolin TD. Antimicrobial-associated QT interval prolongation: pointes of interest. Clin Infect Dis. 2006;43(12):1603–11.
    • (2006) Clin Infect Dis , vol.43 , Issue.12 , pp. 1603-1611
    • Owens, R.C.1    Nolin, T.D.2
  • 82
    • 84888985056 scopus 로고    scopus 로고
    • Azithromycin-induced proarrhythmia and cardiovascular death
    • COI: 1:CAS:528:DC%2BC2cXhs1Ojtr7E, PID: 24285766
    • Howard PA. Azithromycin-induced proarrhythmia and cardiovascular death. Ann Pharmacother. 2013;47(11):1547–51. doi:10.1177/1060028013504905.
    • (2013) Ann Pharmacother , vol.47 , Issue.11 , pp. 1547-1551
    • Howard, P.A.1
  • 83
    • 84877254751 scopus 로고    scopus 로고
    • Use of azithromycin and death from cardiovascular causes
    • COI: 1:CAS:528:DC%2BC3sXnt1Wlt7c%3D, PID: 23635050
    • Svanstrom H, Pasternak B, Hviid A. Use of azithromycin and death from cardiovascular causes. N Engl J Med. 2013;368(18):1704–12. doi:10.1056/NEJMoa1300799.
    • (2013) N Engl J Med , vol.368 , Issue.18 , pp. 1704-1712
    • Svanstrom, H.1    Pasternak, B.2    Hviid, A.3
  • 84
    • 84861076083 scopus 로고    scopus 로고
    • Azithromycin and the risk of cardiovascular death
    • COI: 1:CAS:528:DC%2BC38Xntlamu7c%3D, PID: 22591294
    • Ray WA, Murray KT, Hall K, Arbogast PG, Stein CM. Azithromycin and the risk of cardiovascular death. N Engl J Med. 2012;366(20):1881–90. doi:10.1056/NEJMoa1003833.
    • (2012) N Engl J Med , vol.366 , Issue.20 , pp. 1881-1890
    • Ray, W.A.1    Murray, K.T.2    Hall, K.3    Arbogast, P.G.4    Stein, C.M.5
  • 85
    • 84901775962 scopus 로고    scopus 로고
    • Association of azithromycin with mortality and cardiovascular events among older patients hospitalized with pneumonia
    • PID: 24893087
    • Mortensen EM, Halm EA, Pugh MJ, et al. Association of azithromycin with mortality and cardiovascular events among older patients hospitalized with pneumonia. JAMA. 2014;311(21):2199–208.
    • (2014) JAMA , vol.311 , Issue.21 , pp. 2199-2208
    • Mortensen, E.M.1    Halm, E.A.2    Pugh, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.