Using the Lessons Learned from the Clinic to Improve the Preclinical Development of Antibody Drug Conjugates

Pharmaceutical Research

Volumn 32, Issue 11, 2015, Pages 3458-3469

  Jackson, Dowdy ^a   Stover, David ^a  

^a Agensys Inc   (United States)

Author keywords

antibody drug conjugate; preclinical; site specific

Indexed keywords

ANTIBODY CONJUGATE; CD30 ANTIGEN; CD33 ANTIGEN; CYTOTOXIC AGENT; DRUG ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2; TUMOR ANTIGEN; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

ANTIBODY ENGINEERING; ANTIGEN BINDING; DRUG CONJUGATION; DRUG RESISTANCE; HUMAN; PRIORITY JOURNAL; REVIEW; SOLID TUMOR; ANIMAL; CELL SURVIVAL; CLINICAL TRIAL (TOPIC); DRUG DEVELOPMENT; DRUG EFFECTS; PRECLINICAL STUDY; PROCEDURES; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CLINICAL TRIALS AS TOPIC; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HUMANS; IMMUNOCONJUGATES;

EID: 84943364447     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1536-7     Document Type: Review

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