Three dimensional culture of human renal cell carcinoma organoids

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Batchelder, Cynthia A ^a   Martinez, Michele L ^a   Duru, Nadire ^a   Meyers, Frederick J ^b,c   Tarantal, Alice F ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; CULTURE TECHNIQUE; CYTOPLASM; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; GLOMERULUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY CARCINOMA; MALE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; CELL CULTURE TECHNIQUE; CHEMISTRY; KIDNEY TUMOR; METABOLISM; PATHOLOGY; PROCEDURES; TISSUE SCAFFOLD; TUMOR CELL CULTURE;

CARCINOMA, RENAL CELL; CELL CULTURE TECHNIQUES; FEMALE; HUMANS; KIDNEY NEOPLASMS; MALE; ORGANOIDS; TISSUE SCAFFOLDS; TUMOR CELLS, CULTURED;

EID: 84943339579     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0136758     Document Type: Article

References (37)

1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63:11-30. doi: 10. 3322/caac.21166 PMID: 23335087
2. NIH National Cancer Institute SEER Stat Fact Sheets: Kidney and Renal Pelvis Cancer. http://www.cancer.gov/researchandfunding/snapshots/kidney.
3. Shuch B, Amin A, Armstrong AJ, Eble JN, Ficarra V, Lopez-Beltran A, et al. Understanding pathologic variants of renal cell carcinoma: Distilling therapeutic opportunities from biologic complexity. Eur Urol. 2015;67:85-97. doi: 10.1016/j.eururo.2014.04.029 PMID: 24857407
4. Ebert T, Bander NH, Finstad CL, Ramsawak RD, Old LJ. Establishment and characterization of human renal cancer and normal kidney cell lines. Cancer Res. 1990;50:5531-5536. PMID: 2386958
5. Anglard P, Trahan E, Liu S, Latif F, Merino MJ, Lerman MI, et al. Molecular and cellular characterization of human renal cell carcinoma cell lines. Cancer Res. 1992;52:348-356. PMID: 1345811
6. Valente MJ, Henrique R, Costa VL, Jerónimo C, Carvalho F, Bastos ML, et al. A rapid and simple procedure forthe establishment of human normal and cancer renal primary cell cultures from surgical specimens. PLoS One 2011;6:e19337. doi: 10.1371/journal.pone.0019337 PMID: 21573239
7. Thoma CR, Zimmermann M, Agarkova I, Kelm JM, Krek W. 3D cell culture systems modeling tumor growth determinants in cancertarget discovery. Adv Drug Deliv Rev. 2014;69-70:29-41. doi: 10. 1016/j.addr.2014.03.001 PMID: 24636868
8. Astashkina AI, Mann BK, Prestwich GD, Grainger DW. A 3-D organoid kidney culture model engineered for high-throughput nephrotoxicity assays. Biomaterials 2012;33:4700-4711. doi: 10.1016/j. biomaterials.2012.02.063 PMID: 22444643
9. Astashkina AI, Mann BK, Prestwich GD, Grainger DW. Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines. Biomaterials 2012;33:4712-4721. doi: 10.1016/j.biomaterials.2012.03.001 PMID: 22475530
10. Sato T, Vries RG, Snippert HJ, Vande Wetering M, Barker N, Stange DE, et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 2009;459:262-265. doi: 10. 1038/nature07935 PMID: 19329995
11. Sato T, Clevers H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 2013;340:1190-1194. doi: 10.1126/science.1234852 PMID: 23744940
12. Lancaster MA, Knoblich JA. Organogenesis in a dish: Modeling development and disease using organoid technologies. Science 2014;345:1247125. doi: 10.1126/science.1247125 PMID: 25035496
13. Des Rochers TM, Palma E, Kaplan DL. Tissue-engineered kidney disease models. Adv Drug Deliv Rev. 2014;69-70:67-80. doi: 10.1016/j.addr.2013.12.002 PMID: 24361391
14. Astashkina A, Grainger DW. Critical analysis of 3-D organoid in vitro cell culture models for highthroughput drug candidate toxicity assessments. Adv Drug Deliv Rev. 2014;69-70:1-18. doi: 10. 1016/j.addr.2014.02.008 PMID: 24613390
15. Nakayama KH, Batchelder CA, Lee CI, Tarantal AF. Decellularized rhesus monkey kidney as a three-dimensional scaffold for renal tissue engineering. Tissue Eng. Part A 2010;16:2207-2216. doi: 10. 1089/ten. TEA.2009.0602 PMID: 20156112
16. Nakayama KH, Batchelder CA, Lee CI, Tarantal AF. Renal tissue engineering with decellularized rhesus monkey kidneys: age-related differences. Tissue Eng. Part A 2011;17:2891-2901. doi: 10.1089/ten. TEA.2010.0714 PMID: 21902603
17. Nakayama KH, Lee CC, Batchelder CA, Tarantal AF. Tissue specificity of decellularized rhesus monkey kidney and lung scaffolds. PLoS One 2013;8:e6413.
18. Batchelder CA, Lee CCI, Matsell DG, Yoder MC, Tarantal AF. Renal ontogeny in the rhesus monkey (Macaca mulatta) and directed differentiation of human embryonic stem cells towards kidney precursors. Differentiation 2009;78:45-56. doi: 10.1016/j.diff.2009.05.001 PMID: 19500897
19. Pan CC, Chen PC, Ho DM. The diagnostic utility of MOC31, BerEP4, RCC marker and CD10 in the classification of renal cell carcinoma and renal oncocytoma: an immunohistochemical analysis of 328 cases. Histopathology 2004;45:452-459. PMID: 15500648
20. Leibovich BC, Lohse CM, Crispen PL, Boorjian SA, Thompson RH, Blute ML, et al. Histological subtype is an independent predictor of outcome for patients with renal cell carcinoma. J Urol. 2010;183:1309-1315. doi: 10.1016/j.juro.2009.12.035 PMID: 20171681
21. Cohen HT, McGovern FJ. Renal-Cell Carcinoma. N Engl J Med. 2005;353:2477-2490. PMID: 16339096
22. Bielecka ZF, Czarnecka AM, Szczylik C. Genomic analysis as the first step toward personalized treatment in renal cell carcinoma. Front Oncol. 2014;4:194. doi: 10.3389/fonc.2014.00194 PMID: 25120953
23. Fisher R, Larkin J, Swanton C. Delivering preventive, predictive and personalized cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity. EPMA J. 2011;3:1. doi: 10.1007/s13167-011-0137-3 PMID: 22738081
24. Takahashi M, Rhodes DR, Furge KA, Kanayama H, Kagawa S, Haab BB, et al. Gene expression profiling of clear cell renal cell carcinoma: Gene identification and prognostic classification. Proc Natl Acad Sci. USA 2001;98:9754-9759. PMID: 11493696
25. Brannon AR, Reddy A, Seiler M, Arreola A, Moore DT, Pruthi RS, et al. Molecular stratification of clear cell renal cell carcinoma by consensus clustering reveals distinct subtypes and survival patterns. Genes Cancer 2010;1:154-163.
26. Cancer Genome Atlas Research Network. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 2013;499:43-49. doi: 10.1038/nature12222 PMID: 23792563
27. Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N EnglJ Med. 2012;366:883-892. doi: 10.1056/NEJMoa1113205 PMID: 22397650
28. Cifola I, Bianchi C, Mangano E, Bombelli S, Frascati F, Fasoli E, et al. Renal cell carcinoma primary cultures maintain genomic and phenotypic profile of parental tumor tissues. BMC Cancer 2011;11:244. doi: 10.1186/1471-2407-11-244 PMID: 21668985
29. Bianchi C, Bombelli S, Raimondo F, Torsello B, Angeloni V, Ferrero S, et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am J Pathol. 2010;176:1660-1670. doi: 10.2353/ajpath.2010.090402 PMID: 20167856
30. Hoppensack A, Kazanecki CC, Colter D, Gosiewska A, Schanz J, Walles H, et al. A human in vitro model that mimics the renal proximal tubule. Tissue Eng. Part C 2014;20:599-609.
31. Addla SK, Brown MD, Hart CA, Ramani VAC, Clarke NW. Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells. Am J Physiol Renal Physiol. 2008;295:F680-F687. doi: 10.1152/ajprenal.90286.2008 PMID: 18614618
32. Des Rochers TM, Suter L, Roth A, Kaplan DL. Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicity. PLoS One 2013;8:e59219. doi: 10.1371/journal.pone.0059219 PMID: 23516613
33. Shimazui T, Schalken JA, Kawai K, Kawamoto R, Van Bockhoven A, Oosterwijk E, et al. Role of complex cadherins in cell-cell adhesion evaluated by spheroid formation in renal cell carcinoma cell lines. Oncol Rep. 2004;11:357-360. PMID: 14719067
34. Zhong Y, Guan K, Guo S, Zhou C, Wang D, Ma W, et al. Spheres derived from the human SK-RC-42 renal cell carcinoma cell line are enriched in cancer stem cells. Cancer Lett. 2010;299:150-160. doi: 10.1016/j.canlet.2010.08.013 PMID: 20846785
35. Pavia-Jiménez A, Tcheuyap VT, Grugarolas J. Establishing a human renal cell carcinoma tumorgraft platform for preclinical drug testing. Nat Protoc. 2014;9:1848-1859. doi: 10.1038/nprot.2014.108 PMID: 25010905
36. Sivanand S, Peña-llopis S, Zhao H, Kucejova B, Spence P, Pavia-Jiménez A, et al. A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma. SciTransl Med. 2012;4:137ra75. doi: 10.1126/scitranslmed.3003643 PMID: 22674553
37. Grainger DW. Cell-based drug testing; this world is not flat. AdvDrug Deliv Rev. 2014;69-70: vii-xi. doi: 10.1016/j.addr.2014.04.001 PMID: 24709443