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Volumn 70, Issue 9, 2015, Pages 1156-1162

Serum 25-hydroxyvitamin D, plasma klotho, and lower-extremity physical performance among older adults: Findings from the InCHIANTI Study

Author keywords

Biomarkers; Epidemiology; Metabolism; Physical function; Physical performance

Indexed keywords

25-HYDROXYVITAMIN D; BETA GLUCURONIDASE; KLOTHO PROTEIN; VITAMIN D;

EID: 84943328096     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glv017     Document Type: Article
Times cited : (33)

References (40)
  • 1
    • 0034098121 scopus 로고    scopus 로고
    • Lower extremity function and subsequent disability: Consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery
    • Guralnik JM, Ferrucci L, Pieper CF, et al. Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci. 2000;55:M221-M231.
    • (2000) J Gerontol a Biol Sci Med Sci. , vol.55 , pp. M221-M231
    • Guralnik, J.M.1    Ferrucci, L.2    Pieper, C.F.3
  • 2
    • 78650878358 scopus 로고    scopus 로고
    • Gait speed and survival in older adults
    • Studenski S, Perera S, Patel K, et al. Gait speed and survival in older adults. JAMA. 2011;305:50-58. doi:10.1001/jama.2010.1923
    • (2011) JAMa , vol.305 , pp. 50-58
    • Studenski, S.1    Perera, S.2    Patel, K.3
  • 4
    • 0030724491 scopus 로고    scopus 로고
    • Mutation of the mouse klotho gene leads to a syndrome resembling ageing
    • Kuro-o M, Matsumura Y, Aizawa H, et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature. 1997;390:45-51.
    • (1997) Nature. , vol.390 , pp. 45-51
    • Kuro-O, M.1    Matsumura, Y.2    Aizawa, H.3
  • 5
    • 24944481544 scopus 로고    scopus 로고
    • Suppression of aging in mice by the hormone klotho
    • Kurosu H, Yamamoto M, Clark JD, et al. Suppression of aging in mice by the hormone Klotho. Science. 2005;309:1829-1833.
    • (2005) Science , vol.309 , pp. 1829-1833
    • Kurosu, H.1    Yamamoto, M.2    Clark, J.D.3
  • 6
    • 0034333526 scopus 로고    scopus 로고
    • Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel klotho family protein
    • Ito S, Kinoshita S, Shiraishi N, et al. Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein. Mech Dev. 2000;98:115-119.
    • (2000) Mech Dev. , vol.98 , pp. 115-119
    • Ito, S.1    Kinoshita, S.2    Shiraishi, N.3
  • 7
    • 33845631059 scopus 로고    scopus 로고
    • Klotho converts canonical FGF receptor into a specific receptor for FGF23
    • Urakawa I, Yamazaki Y, Shimada T, et al. Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature. 2006;444:770-774.
    • (2006) Nature. , vol.444 , pp. 770-774
    • Urakawa, I.1    Yamazaki, Y.2    Shimada, T.3
  • 8
    • 80051518025 scopus 로고    scopus 로고
    • Plasma klotho and mortality risk in older community-dwelling adults
    • Semba RD, Cappola AR, Sun K, et al. Plasma klotho and mortality risk in older community-dwelling adults. J Gerontol A Biol Sci Med Sci. 2011;66:794-800. doi:10.1093/gerona/glr058
    • (2011) J Gerontol a Biol Sci Med Sci. , vol.66 , pp. 794-800
    • Semba, R.D.1    Cappola, A.R.2    Sun, K.3
  • 9
    • 84861345426 scopus 로고    scopus 로고
    • Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: The InCHIANTI study
    • Semba RD, Cappola AR, Sun K, et al. Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: the InCHIANTI study. Eur J Appl Physiol. 2012;112:1215-1220. doi:10.1007/s00421-011-2072-3
    • (2012) Eur J Appl Physiol. , vol.112 , pp. 1215-1220
    • Semba, R.D.1    Cappola, A.R.2    Sun, K.3
  • 10
    • 84863451112 scopus 로고    scopus 로고
    • Relationship of low-circulating "anti-aging" klotho hormone with disability in activities of daily living among older community-dwelling adults
    • Crasto CL, Semba RD, Sun K, Cappola AR, Bandinelli S, Ferrucci L. Relationship of low-circulating "anti-aging" klotho hormone with disability in activities of daily living among older community-dwelling adults. Rejuvenation Res. 2012;15:295-301. doi:10.1089/rej.2011.1268
    • (2012) Rejuvenation Res. , vol.15 , pp. 295-301
    • Crasto, C.L.1    Semba, R.D.2    Sun, K.3    Cappola, A.R.4    Bandinelli, S.5    Ferrucci, L.6
  • 11
    • 80054737745 scopus 로고    scopus 로고
    • Plasma klotho and cardiovascular disease in adults
    • Semba RD, Cappola AR, Sun K, et al. Plasma klotho and cardiovascular disease in adults. J Am Geriatr Soc. 2011;59:1596-1601. doi:10.1111/j.1532-5415.2011.03558.x
    • (2011) J Am Geriatr Soc. , vol.59 , pp. 1596-1601
    • Semba, R.D.1    Cappola, A.R.2    Sun, K.3
  • 12
    • 33744784615 scopus 로고    scopus 로고
    • Vitamin D physiology
    • Lips P. Vitamin D physiology. Prog Biophys Mol Biol. 2006;92:4-8.
    • (2006) Prog Biophys Mol Biol. , vol.92 , pp. 4-8
    • Lips, P.1
  • 13
    • 84873710626 scopus 로고    scopus 로고
    • Molecular mechanisms of Vitamin D action
    • Haussler MR, Whitfield GK, Kaneko I, et al. Molecular mechanisms of vitamin D action. Calcif Tissue Int. 2013;92:77-98. doi:10.1007/s00223-012-9619-0
    • (2013) Calcif Tissue Int. , vol.92 , pp. 77-98
    • Haussler, M.R.1    Whitfield, G.K.2    Kaneko, I.3
  • 14
    • 80054945714 scopus 로고    scopus 로고
    • Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells
    • Forster RE, Jurutka PW, Hsieh JC, et al. Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells. Biochem Biophys Res Commun. 2011;414:557-562. doi:10.1016/j.bbrc.2011.09.117.
    • (2011) Biochem Biophys Res Commun. , vol.414 , pp. 557-562
    • Forster, R.E.1    Jurutka, P.W.2    Hsieh, J.C.3
  • 15
    • 84856720641 scopus 로고    scopus 로고
    • Regulation and function of the FGF23/klotho endocrine pathways
    • Martin A, David V, Quarles LD. Regulation and function of the FGF23/klotho endocrine pathways. Physiol Rev. 2012;92:131-155. doi:10.1152/physrev.00002.2011
    • (2012) Physiol Rev. , vol.92 , pp. 131-155
    • Martin, A.1    David, V.2    Quarles, L.D.3
  • 16
    • 63949085198 scopus 로고    scopus 로고
    • Sex-specific association of serum Vitamin D levels with physical function in older adults
    • Dam TT, von Mühlen D, Barrett-Connor EL. Sex-specific association of serum vitamin D levels with physical function in older adults. Osteoporos Int. 2009;20:751-760. doi:10.1007/s00198-008-0749-1
    • (2009) Osteoporos Int. , vol.20 , pp. 751-760
    • Dam, T.T.1    Von Mühlen, D.2    Barrett-Connor, E.L.3
  • 17
    • 34250351913 scopus 로고    scopus 로고
    • Association between Vitamin D status and physical performance: The InCHIANTI study
    • Houston DK, Cesari M, Ferrucci L, et al. Association between vitamin D status and physical performance: the InCHIANTI study. J Gerontol A Biol Sci Med Sci. 2007;62:440-446.
    • (2007) J Gerontol a Biol Sci Med Sci. , vol.62 , pp. 440-446
    • Houston, D.K.1    Cesari, M.2    Ferrucci, L.3
  • 18
    • 80054826057 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D and physical function in older adults: The cardiovascular health study all stars
    • Houston DK, Tooze JA, Davis CC, et al. Serum 25-hydroxyvitamin D and physical function in older adults: the Cardiovascular Health Study All Stars. J Am Geriatr Soc. 2011;59:1793-1801. doi:10.1111/j.1532-5415.2011.03601.x
    • (2011) J Am Geriatr Soc. , vol.59 , pp. 1793-1801
    • Houston, D.K.1    Tooze, J.A.2    Davis, C.C.3
  • 19
    • 0346732368 scopus 로고    scopus 로고
    • Low Vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): The longitudinal aging study Amsterdam
    • Visser M, Deeg DJ, Lips P; Longitudinal Aging Study Amsterdam. Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. J Clin Endocrinol Metab. 2003;88:5766-5772.
    • (2003) J Clin Endocrinol Metab. , vol.88 , pp. 5766-5772
    • Visser, M.1    Deeg, D.J.2    Lips, P.3
  • 20
    • 84896399893 scopus 로고    scopus 로고
    • Associations between serum 25-hydroxyvitamin D concentrations and multiple health conditions, physical performance measures, disability, and all-cause mortality: The concord health and ageing in men project
    • Hirani V, Cumming RG, Naganathan V, et al. Associations between serum 25-hydroxyvitamin D concentrations and multiple health conditions, physical performance measures, disability, and all-cause mortality: the Concord Health and Ageing in Men Project. J Am Geriatr Soc. 2014;62:417-425. doi:10.1111/jgs.12693
    • (2014) J Am Geriatr Soc. , vol.62 , pp. 417-425
    • Hirani, V.1    Cumming, R.G.2    Naganathan, V.3
  • 21
    • 0034540947 scopus 로고    scopus 로고
    • Subsystems contributing to the decline in ability to walk: Bridging the gap between epidemiology and geriatric practice in the InCHIANTI study
    • Ferrucci L, Bandinelli S, Benvenuti E, et al. Subsystems contributing to the decline in ability to walk: bridging the gap between epidemiology and geriatric practice in the InCHIANTI study. J Am Geriatr Soc. 2000;48:1618-1625.
    • (2000) J Am Geriatr Soc. , vol.48 , pp. 1618-1625
    • Ferrucci, L.1    Bandinelli, S.2    Benvenuti, E.3
  • 22
    • 0028292936 scopus 로고
    • A short physical performance battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission
    • Guralnik JM, Simonsick EM, Ferrucci L, et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49:M85-M94.
    • (1994) J Gerontol. , vol.49 , pp. M85-M94
    • Guralnik, J.M.1    Simonsick, E.M.2    Ferrucci, L.3
  • 23
    • 77955272026 scopus 로고    scopus 로고
    • Establishment of sandwich ELISA for soluble alpha-klotho measurement: Age-dependent change of soluble alpha-klotho levels in healthy subjects
    • Yamazaki Y, Imura A, Urakawa I, et al. Establishment of sandwich ELISA for soluble alpha-Klotho measurement: age-dependent change of soluble alpha-Klotho levels in healthy subjects. Biochem Biophys Res Commun. 2010;398:513-518. doi:10.1016/j.bbrc.2010.06.110
    • (2010) Biochem Biophys Res Commun. , vol.398 , pp. 513-518
    • Yamazaki, Y.1    Imura, A.2    Urakawa, I.3
  • 24
    • 34250803923 scopus 로고    scopus 로고
    • Alpha-klotho as a regulator of calcium homeostasis
    • Imura A, Tsuji Y, Murata M, et al. alpha-Klotho as a regulator of calcium homeostasis. Science. 2007;316:1615-1618.
    • (2007) Science , vol.316 , pp. 1615-1618
    • Imura, A.1    Tsuji, Y.2    Murata, M.3
  • 25
    • 65649142017 scopus 로고    scopus 로고
    • A new equation to estimate glomerular filtration rate
    • Levey AS, Stevens LA, Schmid CH, et al; CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration). A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150:604-612.
    • (2009) Ann Intern Med. , vol.150 , pp. 604-612
    • Levey, A.S.1    Stevens, L.A.2    Schmid, C.H.3
  • 26
    • 0032924944 scopus 로고    scopus 로고
    • Causal diagrams for epidemiologic research
    • Greenland S, Pearl J, Robins JM. Causal diagrams for epidemiologic research. Epidemiology. 1999;10:37-48.
    • (1999) Epidemiology , vol.10 , pp. 37-48
    • Greenland, S.1    Pearl, J.2    Robins, J.M.3
  • 27
    • 84922540923 scopus 로고    scopus 로고
    • Doubly robust estimation and causal inference in longitudinal studies with dropout and truncation by death
    • Shardell M, Hicks GE, Ferrucci L. Doubly robust estimation and causal inference in longitudinal studies with dropout and truncation by death. Biostatistics. 2015;16:155-168. doi:10.1093/biostatistics/kxu032
    • (2015) Biostatistics , vol.16 , pp. 155-168
    • Shardell, M.1    Hicks, G.E.2    Ferrucci, L.3
  • 28
    • 67349216949 scopus 로고    scopus 로고
    • Marginal structural models for the estimation of direct and indirect effects
    • VanderWeele TJ. Marginal structural models for the estimation of direct and indirect effects. Epidemiology. 2009;20:18-26. doi:10.1097/EDE.0b013e31818f69ce
    • (2009) Epidemiology , vol.20 , pp. 18-26
    • VanderWeele, T.J.1
  • 30
    • 0033812019 scopus 로고    scopus 로고
    • Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging
    • Utsugi T, Ohno T, Ohyama Y, et al. Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging. Metabolism. 2000;49:1118-1123.
    • (2000) Metabolism , vol.49 , pp. 1118-1123
    • Utsugi, T.1    Ohno, T.2    Ohyama, Y.3
  • 31
    • 77956642900 scopus 로고    scopus 로고
    • Klotho: A novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule
    • Hu MC, Shi M, Zhang J, et al. Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J. 2010;24:3438-3450. doi:10.1096/fj.10-154765
    • (2010) FASEB J. , vol.24 , pp. 3438-3450
    • Hu, M.C.1    Shi, M.2    Zhang, J.3
  • 32
    • 27844561111 scopus 로고    scopus 로고
    • Regulation of oxidative stress by the anti-aging hormone klotho
    • Yamamoto M, Clark JD, Pastor J V, et al. Regulation of oxidative stress by the anti-aging hormone klotho. J Biol Chem. 2005;280:38029-38034.
    • (2005) J Biol Chem. , vol.280 , pp. 38029-38034
    • Yamamoto, M.1    Clark, J.D.2    Pastor, J.V.3
  • 33
    • 0036785320 scopus 로고    scopus 로고
    • Klotho gene polymorphisms associated with bone density of aged postmenopausal women
    • Kawano K, Ogata N, Chiano M, et al. Klotho gene polymorphisms associated with bone density of aged postmenopausal women. J Bone Miner Res. 2002;17:1744-1751.
    • (2002) J Bone Miner Res. , vol.17 , pp. 1744-1751
    • Kawano, K.1    Ogata, N.2    Chiano, M.3
  • 34
    • 0036309298 scopus 로고    scopus 로고
    • Association of klotho gene polymorphism with bone density and spondylosis of the lumbar spine in post-menopausal women
    • Ogata N, Matsumura Y, Shiraki M, et al. Association of klotho gene polymorphism with bone density and spondylosis of the lumbar spine in post-menopausal women. Bone. 2002;31:37-42.
    • (2002) Bone. , vol.31 , pp. 37-42
    • Ogata, N.1    Matsumura, Y.2    Shiraki, M.3
  • 35
    • 33947622052 scopus 로고    scopus 로고
    • Association of the F352V variant of the klotho gene with bone mineral density
    • Riancho JA, Valero C, Hernández JL, et al. Association of the F352V variant of the Klotho gene with bone mineral density. Biogerontology. 2007;8:121-127.
    • (2007) Biogerontology , vol.8 , pp. 121-127
    • Riancho, J.A.1    Valero, C.2    Hernández, J.L.3
  • 36
    • 12844263399 scopus 로고    scopus 로고
    • Association of polymorphisms of the androgen receptor and klotho genes with bone mineral density in Japanese women
    • Yamada Y, Ando F, Niino N, Shimokata H. Association of polymorphisms of the androgen receptor and klotho genes with bone mineral density in Japanese women. J Mol Med (Berl). 2005;83:50-57.
    • (2005) J Mol Med (Berl) , vol.83 , pp. 50-57
    • Yamada, Y.1    Ando, F.2    Niino, N.3    Shimokata, H.4
  • 37
    • 0037470501 scopus 로고    scopus 로고
    • The endocrine regulation of aging by insulinlike signals
    • Tatar M, Bartke A, Antebi A. The endocrine regulation of aging by insulinlike signals. Science. 2003;299:1346-1351.
    • (2003) Science , vol.299 , pp. 1346-1351
    • Tatar, M.1    Bartke, A.2    Antebi, A.3
  • 38
    • 67649834455 scopus 로고    scopus 로고
    • Regulation of renal outer medullary potassium channel and renal K(+) excretion by klotho
    • Cha SK, Hu MC, Kurosu H, Kuro-o M, Moe O, Huang CL. Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho. Mol Pharmacol. 2009;76:38-46. doi:10.1124/mol.109.055780
    • (2009) Mol Pharmacol. , vol.76 , pp. 38-46
    • Cha, S.K.1    Hu, M.C.2    Kurosu, H.3    Kuro-O, M.4    Moe, O.5    Huang, C.L.6
  • 39
    • 43249115330 scopus 로고    scopus 로고
    • Associations between Vitamin D status and pain in older adults: The invecchiare in chianti study
    • Hicks GE, Shardell M, Miller RR, et al. Associations between vitamin D status and pain in older adults: the Invecchiare in Chianti study. J Am Geriatr Soc. 2008;56:785-791. doi:10.1111/j.1532-5415.2008.01644.x
    • (2008) J Am Geriatr Soc. , vol.56 , pp. 785-791
    • Hicks, G.E.1    Shardell, M.2    Miller, R.R.3
  • 40
    • 84862822314 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D, transitions between frailty states, and mortality in older adults: The invecchiare in chianti study
    • Shardell M, D'Adamo C, Alley DE, et al. Serum 25-hydroxyvitamin D, transitions between frailty states, and mortality in older adults: the Invecchiare in Chianti Study. J Am Geriatr Soc. 2012;60:256-264. doi:10.1111/j.1532-5415.2011.03830.x
    • (2012) J Am Geriatr Soc. , vol.60 , pp. 256-264
    • Shardell, M.1    D'Adamo, C.2    Alley, D.E.3


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