Identification of Novel Perfluoroalkyl Ether Carboxylic Acids (PFECAs) and Sulfonic Acids (PFESAs) in Natural Waters Using Accurate Mass Time-of-Flight Mass Spectrometry (TOFMS)

Environmental Science and Technology

Volumn 49, Issue 19, 2015, Pages 11622-11630

  Strynar, Mark ^a   Dagnino, Sonia ^a,b   McMahen, Rebecca ^a,b   Liang, Shuang ^a,b   Lindstrom, Andrew ^a   Andersen, Erik ^a   McMillan, Larry ^c   Thurman, Michael ^d   Ferrer, Imma ^d   Ball, Carol ^e  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b OAK RIDGE INSTITUTE FOR SCIENCE AND EDUCATION   (United States)

^c National Caucus and Center on Black Aged Inc   (United States)

^d University of Colorado at Boulder   (United States)

^e AGILENT TECHNOLOGIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DIMERS; ETHERS; FEATURE EXTRACTION; MASS SPECTROMETRY; SPECTROMETRY; WATER ANALYSIS;

FLUORINATED COMPOUND; IN-SOURCE COLLISION-INDUCED DISSOCIATIONS; LIMITED INFORMATION; NORTH CAROLINA , USA; PER- AND POLYFLUORINATED COMPOUNDS; PERFLUORINATED COMPOUNDS; SEQUENTIAL SAMPLING; TIME OF FLIGHT MASS SPECTROMETRY;

SURFACE WATERS;

CARBOXYLIC ACID; PERFLUOROALKYL ETHER CARBOXYLIC ACID DERIVATIVE; PERFLUOROALKYL ETHER SULFONIC ACID DERIVATIVE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; WATER; ETHER DERIVATIVE; FLUOROCARBON; WATER POLLUTANT;

BIOACCUMULATION; HEALTH RISK; IDENTIFICATION METHOD; MASS SPECTROMETRY; ORGANIC ACID; ORGANIC COMPOUND; POLLUTANT SOURCE; POLLUTION EFFECT; POLLUTION EXPOSURE; RISK FACTOR; STREAMWATER; SURFACE WATER; TOXICITY; WILD POPULATION;

ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; EXTRACTION; LIQUID CHROMATOGRAPHY; MOLECULAR FEATURE EXTRACTION; TIME OF FLIGHT MASS SPECTROMETRY; WATER CONTAMINATION; ANALYSIS; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; FRACTIONATION; HUMAN; NORTH CAROLINA; PROCEDURES; WATER POLLUTANT;

NORTH CAROLINA; UNITED STATES;

CARBOXYLIC ACIDS; CHEMICAL FRACTIONATION; ETHERS; FLUOROCARBONS; HUMANS; NORTH CAROLINA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONIC ACIDS; WATER; WATER POLLUTANTS, CHEMICAL;

EID: 84943268127     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/acs.est.5b01215     Document Type: Article

References (27)

1. Lindstrom, A. B.; Strynar, M. J.; Libelo, E. L. Polyfluorinated Compounds: Past, Present, and Future Environ. Sci. Technol. 2011, 45 (19) 7954-7961 10.1021/es2011622
2. Houde, M.; De Silva, A. O.; Muir, D. C. G.; Letcher, R. J. Monitoring of Perfluorinated Compounds in Aquatic Biota: An Updated Review Environ. Sci. Technol. 2011, 45 (19) 7962-7973 10.1021/es104326w
3. U.S. EPA. 2010/15 PFOA Stewardship Program. http://www.epa.gov/oppt/pfoa/pubs/stewardship/index.html.
4. Buck, R. C.; Franklin, J.; Berger, U.; Conder, J. M.; Cousins, I. T.; de Voogt, P.; Jensen, A. A.; Kannan, K.; Mabury, S. A.; van Leeuwen, S. P. Perfluoroalkyl and polyfluoroalkyl substances in the environment: terminology, classification, and origins Integr. Environ. Assess. Manage. 2011, 7 (4) 513-41 10.1002/ieam.258
5. Gordon, S. C. Toxicological evaluation of ammonium 4,8-dioxa-3H-perfluorononanoate, a new emulsifier to replace ammonium perfluorooctanoate in fluoropolymer manufacturing Regul. Toxicol. Pharmacol. 2011, 59 (1) 64-80 10.1016/j.yrtph.2010.09.008
6. West Virginia Department of Environmental Protection. Executed Draft Consent Order No. 7418. http://www.dep.wv.gov/pio/Documents/DuPont%20Final%20Version.pdf.
7. Steenland, K.; Fletcher, T.; Savitz, D. A. Epidemiologic Evidence on the Health Effects of Perfluorooctanoic Acid (PFOA) Environ. Health Perspect. 2010, 118 (8) 1100-1108 10.1289/ehp.0901827
8. MacNeil, J.; Steenland, N. K.; Shankar, A.; Ducatman, A. A cross-sectional analysis of type II diabetes in a community with exposure to perfluorooctanoic acid (PFOA) Environ. Res. 2009, 109 (8) 997-1003 10.1016/j.envres.2009.08.002
9. Steenland, K.; Tinker, S.; Frisbee, S.; Ducatman, A.; Vaccarino, V. Association of Perfluorooctanoic Acid and Perfluorooctane Sulfonate With Serum Lipids Among Adults Living Near a Chemical Plant Am. J. Epidemiol. 2009, 170 (10) 1268-1278 10.1093/aje/kwp279
10. Nakayama, S.; Strynar, M.; Helfant, L.; Egeghy, P.; Ye, X.; Lindstrom, A. B. Perfluorinated Compounds in the Cape Fear Drainage Basin in North Carolina Environ. Sci. Technol. 2007, 41, 5271-5276 10.1021/es070792y
11. Hollender, J.; Bourgin, M.; Fenner, K. B.; Longrée, P.; Mcardell, C. S.; Moschet, C.; Ruff, M.; Schymanski, E. L.; Singer, H. P. Exploring the Behaviour of Emerging Contaminants in the Water Cycle using the Capabilities of High Resolution Mass Spectrometry Chimia 2014, 68 (11) 793-798 10.2533/chimia.2014.793
12. Schymanski, E. L.; Singer, H. P.; Longrée, P.; Loos, M.; Ruff, M.; Stravs, M. A.; Ripollés Vidal, C.; Hollender, J. Strategies to Characterize Polar Organic Contamination in Wastewater: Exploring the Capability of High Resolution Mass Spectrometry Environ. Sci. Technol. 2014, 48 (3) 1811-1818 10.1021/es4044374
13. Schymanski, E. L.; Singer, H. P.; Slobodnik, J.; Ipolyi, I. M.; Oswald, P.; Krauss, M.; Schulze, T.; Haglund, P.; Letzel, T.; Grosse, S.; Thomaidis, N. S.; Bletsou, A.; Zwiener, C.; Ibanez, M.; Portoles, T.; de Boer, R.; Reid, M. J.; Onghena, M.; Kunkel, U.; Schulz, W.; Guillon, A.; Noyon, N.; Leroy, G.; Bados, P.; Bogialli, S.; Stipanicev, D.; Rostkowski, P.; Hollender, J. Non-target screening with high-resolution mass spectrometry: critical review using a collaborative trial on water analysis Anal. Bioanal. Chem. 2015, 407, 6237 10.1007/s00216-015-8681-7
14. Schymanski, E. L.; Jeon, J.; Gulde, R.; Fenner, K.; Ruff, M.; Singer, H. P.; Hollender, J. Identifying Small Molecules via High Resolution Mass Spectrometry: Communicating Confidence Environ. Sci. Technol. 2014, 48 (4) 2097-2098 10.1021/es5002105
15. Nakayama, S.; Strynar, M. J.; Helfant, L.; Egeghy, P.; Ye, X.; Lindstrom, A. B. Perfluorinated compounds in the Cape Fear Drainage Basin in North Carolina Environ. Sci. Technol. 2007, 41 (15) 5271-6 10.1021/es070792y
16. Nakayama, S. F.; Strynar, M. J.; Reiner, J. L.; Delinsky, A. D.; Lindstrom, A. B. Determination of Perfluorinated Compounds in the Upper Mississippi River Basin Environ. Sci. Technol. 2010, 44 (11) 4103-4109 10.1021/es100382z
17. Trier, X.; Granby, K.; Christensen, J. H. Tools to discover anionic and nonionic polyfluorinated alkyl surfactants by liquid chromatography electrospray ionisation mass spectrometry J. Chromatogr. A 2011, 1218 (40) 7094-104 10.1016/j.chroma.2011.07.057
18. Ferrer, I.; Thurman, E. M. Liquid Chromatography Time-of-Flight Mass Spectrometry; Wiley: Hoboken, NJ, 2009.
19. Kind, T.; Fiehn, O. Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry BMC Bioinf. 2007, 8 (1) 105 10.1186/1471-2105-8-105
20. Wang, Z.; Cousins, I. T.; Scheringer, M.; Hungerbühler, K. Fluorinated alternatives to long-chain perfluoroalkyl carboxylic acids (PFCAs), perfluoroalkane sulfonic acids (PFSAs) and their potential precursors Environ. Int. 2013, 60 (0) 242-248 10.1016/j.envint.2013.08.021
21. NCDENR. Onsite PFOA Groundwater Monitoring Report 12-9-13; p 6. https://edm.nc.gov/DENR-Portal/; full text search HW-F-NCD047368642-12-09-2013-GW-GMR.
22. USEPA. Envirofacts. http://iaspub.epa.gov/enviro/tsca.get-chem-info?v-registry-id=110000559609. 2015.
23. D'Agostino, L. A.; Mabury, S. A. Identification of novel fluorinated surfactants in aqueous film forming foams and commercial surfactant concentrates Environ. Sci. Technol. 2014, 48 (1) 121-9 10.1021/es403729e
24. Scheringer, M.; Trier, X.; Cousins, I. T.; de Voogt, P.; Fletcher, T.; Wang, Z.; Webster, T. F. Helsingør Statement on poly- and perfluorinated alkyl substances (PFASs) Chemosphere 2014, 114 (0) 337-339 10.1016/j.chemosphere.2014.05.044
25. Blum, A.; Balan, S.A.; Scheringer, M.; Goldenman, G.; Trier, X.; Cousins, I.; Diamond, M.; Fletcher, T.; Higgins, C.; Lindeman, A. A.; Peaslee, G.; de Voogt, P.; Wang, Z.; Weber, R. Madrid Statement Environ. Health Perspect. 2015, 123, A107 10.1289/ehp.1509934
26. Lau, C.; Anitole, K.; Hodes, C.; Lai, D.; Pfahles-Hutchens, A.; Seed, J. Perfluoroalkyl acids: a review of monitoring and toxicological findings Toxicol. Sci. 2007, 99 (2) 366-94 10.1093/toxsci/kfm128
27. European Chemical Agency (ECHA). Registered Substances. http://echa.europa.eu/information-on-chemicals/registered-substances. 2015.