-
1
-
-
44449148845
-
Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats
-
Adijiang A. Goto S. Uramoto S. Nishijima F. Niwa T. (2008) Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats. Nephrol Dial Transplant 23: 1892–1901.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 1892-1901
-
-
Adijiang, A.1
Goto, S.2
Uramoto, S.3
Nishijima, F.4
Niwa, T.5
-
2
-
-
70849098235
-
An oral sorbent, AST-120, increases Klotho expression and inhibits cell senescence in the kidney of uremic rats
-
Adijiang A. Niwa T. (2010) An oral sorbent, AST-120, increases Klotho expression and inhibits cell senescence in the kidney of uremic rats. Am J Nephrol 31: 160–164.
-
(2010)
Am J Nephrol
, vol.31
, pp. 160-164
-
-
Adijiang, A.1
Niwa, T.2
-
3
-
-
68849123039
-
Effect of a carbonaceous oral adsorbent on the progression of CKD: a multicenter, randomized, controlled trial
-
Akizawa T. Asano Y. Morita S. Wakita T. Onishi Y. Fukuhara S. et al. (2009) Effect of a carbonaceous oral adsorbent on the progression of CKD: a multicenter, randomized, controlled trial. Am J Kidney Dis 54: 459–467.
-
(2009)
Am J Kidney Dis
, vol.54
, pp. 459-467
-
-
Akizawa, T.1
Asano, Y.2
Morita, S.3
Wakita, T.4
Onishi, Y.5
Fukuhara, S.6
-
4
-
-
0033646505
-
Therapeutic effects of an oral adsorbent on acute dextran sulphate sodium-induced colitis and its recovery phase in rats, especially effects of elimination of bile acids in gut lumen
-
Araki Y. Tsujikawa T. Andoh A. Sasaki M. Fujiyama Y. Bamba T., (2000) Therapeutic effects of an oral adsorbent on acute dextran sulphate sodium-induced colitis and its recovery phase in rats, especially effects of elimination of bile acids in gut lumen. Dig Liver Dis 32: 691–698.
-
(2000)
Dig Liver Dis
, vol.32
, pp. 691-698
-
-
Araki, Y.1
Tsujikawa, T.2
Andoh, A.3
Sasaki, M.4
Fujiyama, Y.5
Bamba, T.6
-
5
-
-
10744225624
-
Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
-
Barbara G. Stanghellini V. de Giorgio R. Cremon C. Cottrell G. Santini D. et al. (2004) Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology 126: 693–702.
-
(2004)
Gastroenterology
, vol.126
, pp. 693-702
-
-
Barbara, G.1
Stanghellini, V.2
de Giorgio, R.3
Cremon, C.4
Cottrell, G.5
Santini, D.6
-
7
-
-
84859111005
-
Brain–gut axis: from basic understanding to treatment of IBS and related disorders
-
Camilleri M. Di Lorenzo C. (2012) Brain–gut axis: from basic understanding to treatment of IBS and related disorders. J Pediatr Gastroenterol Nutr 54: 446–453.
-
(2012)
J Pediatr Gastroenterol Nutr
, vol.54
, pp. 446-453
-
-
Camilleri, M.1
Di Lorenzo, C.2
-
8
-
-
1642480079
-
The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair
-
Dou L. Bertrand E. Cerini C. Faure V. Sampol J. Vanholder R. et al. (2004) The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair. Kidney Int 65: 442–451.
-
(2004)
Kidney Int
, vol.65
, pp. 442-451
-
-
Dou, L.1
Bertrand, E.2
Cerini, C.3
Faure, V.4
Sampol, J.5
Vanholder, R.6
-
9
-
-
84879938040
-
Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease
-
El-Salhy M. Wendelbo I. Gundersen D. (2013) Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease. Mol Med Rep 8: 451–455.
-
(2013)
Mol Med Rep
, vol.8
, pp. 451-455
-
-
El-Salhy, M.1
Wendelbo, I.2
Gundersen, D.3
-
10
-
-
0347028168
-
Acute stress modulates the histamine content of mast cells in the gastrointestinal tract through interleukin-1 and corticotropin-releasing factor release in rats
-
Eutamene H. Theodorou V. Fioramonti J. Bueno L. (2003) Acute stress modulates the histamine content of mast cells in the gastrointestinal tract through interleukin-1 and corticotropin-releasing factor release in rats. J Physiol 553: 959–966.
-
(2003)
J Physiol
, vol.553
, pp. 959-966
-
-
Eutamene, H.1
Theodorou, V.2
Fioramonti, J.3
Bueno, L.4
-
12
-
-
67651092321
-
Oral charcoal adsorbent (AST-120) prevents progression of cardiac damage in chronic kidney disease through suppression of oxidative stress
-
Fujii H. Nishijima F. Goto S. Sugano M. Yamato H. Kitazawa R. et al. (2009) Oral charcoal adsorbent (AST-120) prevents progression of cardiac damage in chronic kidney disease through suppression of oxidative stress. Nephrol Dial Transplant 24: 2089–2095.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 2089-2095
-
-
Fujii, H.1
Nishijima, F.2
Goto, S.3
Sugano, M.4
Yamato, H.5
Kitazawa, R.6
-
13
-
-
44449118921
-
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
-
Furuhashi M. Hotamisligil G. (2008) Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets. Nat Rev Drug Discov 7: 489–503.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 489-503
-
-
Furuhashi, M.1
Hotamisligil, G.2
-
14
-
-
4644221457
-
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
-
Go A. Chertow G. Fan D. McCulloch C. Hsu C. (2004) Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351: 1296–1305.
-
(2004)
N Engl J Med
, vol.351
, pp. 1296-1305
-
-
Go, A.1
Chertow, G.2
Fan, D.3
McCulloch, C.4
Hsu, C.5
-
15
-
-
33644867569
-
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
-
Inagaki T. Moschetta A. Lee Y. Peng L. Zhao G. Downes M. et al. (2006) Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor. Proc Natl Acad Sci U S A 103: 3920–3925.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3920-3925
-
-
Inagaki, T.1
Moschetta, A.2
Lee, Y.3
Peng, L.4
Zhao, G.5
Downes, M.6
-
16
-
-
84899996881
-
Effect of AST-120 on endothelial dysfunction in adenine-induced uremic rats
-
Inami Y. Hamada C. Seto T. Hotta Y. Aruga S. Inuma J. et al. (2014) Effect of AST-120 on endothelial dysfunction in adenine-induced uremic rats. Int J Nephrol 2014: 164125.
-
(2014)
Int J Nephrol
, vol.2014
, pp. 164125
-
-
Inami, Y.1
Hamada, C.2
Seto, T.3
Hotta, Y.4
Aruga, S.5
Inuma, J.6
-
17
-
-
78649821640
-
Indoxyl sulfate induces leukocyte-endothelial interactions through up-regulation of E-selectin
-
Ito S. Osaka M. Higuchi Y. Nishijima F. Ishii H. Yoshida M. (2010) Indoxyl sulfate induces leukocyte-endothelial interactions through up-regulation of E-selectin. J Biol Chem 285: 38869–38875.
-
(2010)
J Biol Chem
, vol.285
, pp. 38869-38875
-
-
Ito, S.1
Osaka, M.2
Higuchi, Y.3
Nishijima, F.4
Ishii, H.5
Yoshida, M.6
-
18
-
-
33846390391
-
Modification of cardiovascular risk in hemodialysis patients: an evidence-based review
-
Johnson D. Craven A. Isbel N. (2007) Modification of cardiovascular risk in hemodialysis patients: an evidence-based review. Hemodial Int 11: 1–14.
-
(2007)
Hemodial Int
, vol.11
, pp. 1-14
-
-
Johnson, D.1
Craven, A.2
Isbel, N.3
-
19
-
-
77953241787
-
Gut hormones: emerging role in immune activation and inflammation
-
Khan W. Ghia J. (2010) Gut hormones: emerging role in immune activation and inflammation. Clin Exp Immunol 161: 19–27.
-
(2010)
Clin Exp Immunol
, vol.161
, pp. 19-27
-
-
Khan, W.1
Ghia, J.2
-
20
-
-
48949090236
-
AST-120 (Kremezin) initiated in early stage chronic kidney disease stunts the progression of renal dysfunction in type 2 diabetic subjects
-
Konishi K. Nakano S. Tsuda S. Nakagawa A. Kigoshi T. Koya D. (2008) AST-120 (Kremezin) initiated in early stage chronic kidney disease stunts the progression of renal dysfunction in type 2 diabetic subjects. Diabetes Res Clin Pract 81: 310–315.
-
(2008)
Diabetes Res Clin Pract
, vol.81
, pp. 310-315
-
-
Konishi, K.1
Nakano, S.2
Tsuda, S.3
Nakagawa, A.4
Kigoshi, T.5
Koya, D.6
-
21
-
-
77954342329
-
Effects of an oral adsorbent on oxidative stress and fibronectin expression in experimental diabetic nephropathy
-
Lee S. Nam B. Kang E. Han S. Li J. Kim do H. et al. (2010) Effects of an oral adsorbent on oxidative stress and fibronectin expression in experimental diabetic nephropathy. Nephrol Dial Transplant 25: 2134–2141.
-
(2010)
Nephrol Dial Transplant
, vol.25
, pp. 2134-2141
-
-
Lee, S.1
Nam, B.2
Kang, E.3
Han, S.4
Li, J.5
Kim do, H.6
-
22
-
-
64149095859
-
Long-term effects of the oral adsorbent, AST-120, in patients with chronic renal failure
-
Maeda K. Hamada C. Hayashi T. Shou I. Wakabayashi M. Fukui M. et al. (2009) Long-term effects of the oral adsorbent, AST-120, in patients with chronic renal failure. J Int Med Res 37: 205–213.
-
(2009)
J Int Med Res
, vol.37
, pp. 205-213
-
-
Maeda, K.1
Hamada, C.2
Hayashi, T.3
Shou, I.4
Wakabayashi, M.5
Fukui, M.6
-
23
-
-
33745089703
-
Effect of repeated oral administrations of the oral adsorbent AST-120 on serum creatinine and other markers of renal function. A randomized controlled study in patients with chronic kidney disease
-
Marier J. Lee J. Kambhampati S. Galitz L. Vargas R. Moberly J. et al. (2006) Effect of repeated oral administrations of the oral adsorbent AST-120 on serum creatinine and other markers of renal function. A randomized controlled study in patients with chronic kidney disease. Am J Nephrol 26: 136–141.
-
(2006)
Am J Nephrol
, vol.26
, pp. 136-141
-
-
Marier, J.1
Lee, J.2
Kambhampati, S.3
Galitz, L.4
Vargas, R.5
Moberly, J.6
-
26
-
-
84875890159
-
Review article: Associations between immune activation, intestinal permeability and the irritable bowel syndrome
-
Matricon J. Meleine M. Gelot A. Piche T. Dapoigny M. Muller E. et al. (2012) Review article: Associations between immune activation, intestinal permeability and the irritable bowel syndrome. Aliment Pharmacol Ther 36: 1009–1031.
-
(2012)
Aliment Pharmacol Ther
, vol.36
, pp. 1009-1031
-
-
Matricon, J.1
Meleine, M.2
Gelot, A.3
Piche, T.4
Dapoigny, M.5
Muller, E.6
-
28
-
-
70350031206
-
The uremic retention solute p-cresyl sulfate and markers of endothelial damage
-
Meijers B. Van, Kerckhoven S. Verbeke K. Dehaen W. Vanrenterghem Y. Hoylaerts M. et al. (2009) The uremic retention solute p-cresyl sulfate and markers of endothelial damage. Am J Kidney Dis 54: 891–901.
-
(2009)
Am J Kidney Dis
, vol.54
, pp. 891-901
-
-
Meijers, B.1
Van, Kerckhoven, S.2
Verbeke, K.3
Dehaen, W.4
Vanrenterghem, Y.5
Hoylaerts, M.6
-
29
-
-
77953702891
-
The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions
-
Miyamoto Y. Iwao Y. Tasaki Y. Sato K. Ishima Y. Watanabe H. et al. (2010) The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions. FEBS Lett 584: 2816–2820.
-
(2010)
FEBS Lett
, vol.584
, pp. 2816-2820
-
-
Miyamoto, Y.1
Iwao, Y.2
Tasaki, Y.3
Sato, K.4
Ishima, Y.5
Watanabe, H.6
-
30
-
-
0033762864
-
An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-beta1 in uraemic rat kidneys
-
Miyazaki T. Aoyama I. Ise M. Seo H. Niwa T. (2000) An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-beta1 in uraemic rat kidneys. Nephrol Dial Transplant 15: 1773–1781.
-
(2000)
Nephrol Dial Transplant
, vol.15
, pp. 1773-1781
-
-
Miyazaki, T.1
Aoyama, I.2
Ise, M.3
Seo, H.4
Niwa, T.5
-
31
-
-
0242669257
-
Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells
-
Motojima M. Hosokawa A. Yamato H. Muraki T. Yoshioka T. (2003) Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells. Kidney Int 63: 1671–1680.
-
(2003)
Kidney Int
, vol.63
, pp. 1671-1680
-
-
Motojima, M.1
Hosokawa, A.2
Yamato, H.3
Muraki, T.4
Yoshioka, T.5
-
32
-
-
84863887217
-
Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress
-
Muteliefu G. Shimizu H. Enomoto A. Nishijima F. Takahashi M. Niwa T. (2012) Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress. Am J Physiol Cell Physiol 303: C126-C134.
-
(2012)
Am J Physiol Cell Physiol
, vol.303
, pp. C126-C134
-
-
Muteliefu, G.1
Shimizu, H.2
Enomoto, A.3
Nishijima, F.4
Takahashi, M.5
Niwa, T.6
-
33
-
-
33845729891
-
An oral adsorbent, AST-120, suppresses oxidative stress in uremic rats
-
Nakagawa N. Hasebe N. Sumitomo K. Fujino T. Fukuzawa J. Hirayama T. et al. (2006) An oral adsorbent, AST-120, suppresses oxidative stress in uremic rats. Am J Nephrol 26: 455–461.
-
(2006)
Am J Nephrol
, vol.26
, pp. 455-461
-
-
Nakagawa, N.1
Hasebe, N.2
Sumitomo, K.3
Fujino, T.4
Fukuzawa, J.5
Hirayama, T.6
-
35
-
-
78751644527
-
Oral adsorbent AST-120 ameliorates tubular injury in chronic renal failure patients by reducing proteinuria and oxidative stress generation
-
Nakamura T. Sato E. Fujiwara N. Kawagoe Y. Suzuki T. Ueda Y. et al. (2011) Oral adsorbent AST-120 ameliorates tubular injury in chronic renal failure patients by reducing proteinuria and oxidative stress generation. Metabolism 60: 260–264.
-
(2011)
Metabolism
, vol.60
, pp. 260-264
-
-
Nakamura, T.1
Sato, E.2
Fujiwara, N.3
Kawagoe, Y.4
Suzuki, T.5
Ueda, Y.6
-
37
-
-
33645240056
-
Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome
-
Park J. Rhee P. Kim H. Lee J. Kim Y. Kim J. et al. (2006) Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome. J Gastroenterol Hepatol 21: 71–78.
-
(2006)
J Gastroenterol Hepatol
, vol.21
, pp. 71-78
-
-
Park, J.1
Rhee, P.2
Kim, H.3
Lee, J.4
Kim, Y.5
Kim, J.6
-
38
-
-
33846659447
-
P-cresylsulphate, the main in vivo metabolite of p-cresol, activates leucocyte free radical production
-
Schepers E. Meert N. Glorieux G. Goeman J. van der Eycken J. Vanholder R. (2007) P-cresylsulphate, the main in vivo metabolite of p-cresol, activates leucocyte free radical production. Nephrol Dial Transplant 22: 592–596.
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 592-596
-
-
Schepers, E.1
Meert, N.2
Glorieux, G.3
Goeman, J.4
van der Eycken, J.5
Vanholder, R.6
-
39
-
-
84893381600
-
AST-120 for the management of progression of chronic kidney disease
-
Schulman G. Vanholder R. Niwa T. (2014) AST-120 for the management of progression of chronic kidney disease. Int J Nephrol Renovasc Dis 7: 49–56.
-
(2014)
Int J Nephrol Renovasc Dis
, vol.7
, pp. 49-56
-
-
Schulman, G.1
Vanholder, R.2
Niwa, T.3
-
40
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR / BAR impairs bile acid and lipid homeostasis
-
Sinal C. Tohkin M. Miyata M. Ward J. Lambert G. Gonzalez F. (2000) Targeted disruption of the nuclear receptor FXR / BAR impairs bile acid and lipid homeostasis. Cell 102: 731–744.
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.1
Tohkin, M.2
Miyata, M.3
Ward, J.4
Lambert, G.5
Gonzalez, F.6
-
41
-
-
78049448639
-
Cardiorenal protective effect of the oral uremic toxin absorbent AST-120 in chronic heart disease patients with moderate CKD
-
Shibahara H. Shibahara N. (2010) Cardiorenal protective effect of the oral uremic toxin absorbent AST-120 in chronic heart disease patients with moderate CKD. J Nephrol 23: 535–540.
-
(2010)
J Nephrol
, vol.23
, pp. 535-540
-
-
Shibahara, H.1
Shibahara, N.2
-
42
-
-
33846794398
-
Prospective randomized study evaluating the efficacy of the spherical adsorptive carbon AST-120 in chronic kidney disease patients with moderate decrease in renal function
-
Shoji T. Wada A. Inoue K. Hayashi D. Tomida K. Furumatsu Y. et al. (2007) Prospective randomized study evaluating the efficacy of the spherical adsorptive carbon AST-120 in chronic kidney disease patients with moderate decrease in renal function. Nephron Clin Pract 105: c99–c107.
-
(2007)
Nephron Clin Pract
, vol.105
, pp. c99-c107
-
-
Shoji, T.1
Wada, A.2
Inoue, K.3
Hayashi, D.4
Tomida, K.5
Furumatsu, Y.6
-
43
-
-
84908293797
-
Irritable bowel syndrome: a clinical review
-
Soares R. (2014) Irritable bowel syndrome: a clinical review. World J Gastroenterol 20: 12144–12160.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 12144-12160
-
-
Soares, R.1
-
44
-
-
80053193146
-
Randomised clinical trial: the safety and efficacy of AST-120 in non-constipating irritable bowel syndrome – a double-blind, placebo-controlled study
-
Tack J. Miner P. Jr Fischer L. Harris M. (2011) Randomised clinical trial: the safety and efficacy of AST-120 in non-constipating irritable bowel syndrome – a double-blind, placebo-controlled study. Aliment Pharmacol Ther 34: 868–877.
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 868-877
-
-
Tack, J.1
Miner, P.2
Fischer, L.3
Harris, M.4
-
45
-
-
54249083025
-
AST-120 treatment in pre-dialysis period affects the prognosis in patients on hemodialysis
-
Ueda H. Shibahara N. Takagi S. Inoue T. Katsuoka Y. (2008) AST-120 treatment in pre-dialysis period affects the prognosis in patients on hemodialysis. Ren Fail 30: 856–860.
-
(2008)
Ren Fail
, vol.30
, pp. 856-860
-
-
Ueda, H.1
Shibahara, N.2
Takagi, S.3
Inoue, T.4
Katsuoka, Y.5
-
47
-
-
84855463406
-
Combination of allergic factors can worsen diarrheic irritable bowel syndrome: role of barrier defects and mast cells
-
Vivinus-Nebot M. Dainese R. Anty R. Saint-Paul M. Nano J. Gonthier N. et al. (2012) Combination of allergic factors can worsen diarrheic irritable bowel syndrome: role of barrier defects and mast cells. Am J Gastroenterol 107: 75–81.
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 75-81
-
-
Vivinus-Nebot, M.1
Dainese, R.2
Anty, R.3
Saint-Paul, M.4
Nano, J.5
Gonthier, N.6
-
48
-
-
84875710102
-
p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase
-
Watanabe H. Miyamoto Y. Honda D. Tanaka H. Wu Q. Endo M. et al. (2013) p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase. Kidney Int 83: 582–592.
-
(2013)
Kidney Int
, vol.83
, pp. 582-592
-
-
Watanabe, H.1
Miyamoto, Y.2
Honda, D.3
Tanaka, H.4
Wu, Q.5
Endo, M.6
-
49
-
-
70049093874
-
Oral adsorbents for preventing or delaying the progression of chronic kidney disease
-
Wu H. Sun H. Wang F. Yang M. Dong B. Liu G. (2014) Oral adsorbents for preventing or delaying the progression of chronic kidney disease. Cochrane Database Syst Rev 10: CD007861.
-
(2014)
Cochrane Database Syst Rev
, vol.10
, pp. CD007861
-
-
Wu, H.1
Sun, H.2
Wang, F.3
Yang, M.4
Dong, B.5
Liu, G.6
|