Combination of allergic factors can worsen diarrheic irritable bowel syndrome: Role of barrier defects and mast cells

American Journal of Gastroenterology

Volumn 107, Issue 1, 2012, Pages 75-81

  Vivinus Nebot M ^a,b   Dainese, R ^a   Anty, R ^a,c   Saint Paul, M C ^d   Nano, J L ^a   Gonthier, N ^a,b   Marjoux, S ^a   Frin Mathy, G ^a   Bernard, G ^a,b   Hebuterne X ^a   Tran, A ^a,c   Theodorou, V ^e   Piche, T ^a,b,f  

^a UNIVERSITÉ CÔTE D'AZUR   (France)

^b INSERM   (France)

^c CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^d PASTEUR HOSPITAL   (France)

^e EMRInra Purpan   (France)

^f CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; TRYPTASE;

ADULT; ALLERGY; ARTICLE; ATOPY; CLINICAL ARTICLE; COLON BIOPSY; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; FEMALE; FOOD ALLERGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE MUCOSA PERMEABILITY; IRRITABLE COLON; MALE; MAST CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SKIN TEST;

ADULT; CELL MEMBRANE PERMEABILITY; COLON; DIARRHEA; FEMALE; HUMANS; HYPERSENSITIVITY; INTESTINAL MUCOSA; IRRITABLE BOWEL SYNDROME; MALE; MAST CELLS; MIDDLE AGED; SEVERITY OF ILLNESS INDEX;

EID: 84855463406     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2011.315     Document Type: Article

References (40)

1. Longstreth GF, Thompson WG, Chey WD et al. Functional bowel disorders. Gastroenterology 2006; 130: 1480-91.
2. Collins SM, Piche T, Rampal P. The putative role of infl ammation in the irritable bowel syndrome. Gut 2001; 49: 743-5. (Pubitemid 33096023)
3. Chadwick VS, Chen W, Shu D et al. Activation of the mucosal immune system in irritable bowel syndrome. Gastroenterology 2002; 122: 1778-83. (Pubitemid 34651421)
4. Dunlop SP, Jenkins D, Neal KR et al. Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS. Gastroenterology 2003; 125: 1651-9. (Pubitemid 37500429)
5. Gwee KA, Collins SM, Read NW et al. Increased rectal mucosal expression of interleukin 1beta in recently acquired post-infectious irritable bowel syndrome. Gut 2003; 52: 523-6. (Pubitemid 36363405)
6. Farhadi A, Fields JZ, Keshavarzian A. Mucosal mast cells are pivotal elements in infl ammatory bowel disease that connect the dots: stress, intestinal hyperpermeability and infl ammation. World J Gastroenterol 2007; 13: 3027-30. (Pubitemid 47045457)
7. O ' Sullivan M, Clayton N, Breslin NP et al. Increased mast cells in the irritable bowel syndrome. Neurogastroenterol Motil 2000; 12: 449-57.
8. Guilarte M, Santos J, de Torres I et al. Diarrhoea-predominant IBS patients show mast cell activation and hyperplasia in the jejunum. Gut 2007; 56: 203-9.
9. Piche T, Saint-Paul MC, Dainese R et al. Mast cells and cellularity of the colonic mucosa correlated with fatigue and depression in irritable bowel syndrome. Gut 2008; 57: 468-73. (Pubitemid 351442529)
10. Buhner S, Li Q, Vignali S et al. Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome. Gastroenterology 2009; 137: 1425-34.
11. Cenac N, Andrews CN, Holzhausen M et al. Role for protease activity in visceral pain in irritable bowel syndrome. J Clin Invest 2007; 117: 636-47. (Pubitemid 46348522)
12. Barbara G, Stanghellini V, De Giorgio R et al. Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology 2004; 126: 693-702. (Pubitemid 38298317)
13. Kumar V, Sharma A. Mast cells: emerging sentinel innate immune cells with diverse role in immunity. Molecular Immunol 2010; 48: 14-25.
14. Dvorak AM, Monahan RA, Osage JE et al. Mast-cell degranulation in Crohn's disease. Lancet 1978; 1: 498.
15. Dainese R, Galliani EA, De Lazzari F et al. Discrepancies between reported food intolerance and sensitization test findings in irritable bowel syndrome patients. Am J Gastroenterol 1999; 94: 1892-7. (Pubitemid 29315906)
16. Spiller RC, Jenkins D, Th ornley JP et al. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut 2000; 47: 804-11.
17. Dunlop SP, Hebden J, Campbell E et al. Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndromes. Am J Gastroenterol 2006; 101: 1288-94. (Pubitemid 43829995)
18. Piche T, Barbara G, Aubert P et al. Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators. Gut 2009; 58: 196-201.
19. Zhou QQ, Zhang B, Verne N. Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome. Pain 2009; 146: 41-6.
20. Park MI, Camilleri M. Is there a role of food allergy in irritable bowel syndrome and functional dyspepsia? A systematic review. Neurogastroenterol Motil 2006; 18: 595-607. (Pubitemid 44079763)
21. Lillestol K, Helgeland L, Arslan Lied G et al. Indications of " atopic bowel " in patients with self-reported food hypersensitivity. Aliment Pharmacol Ther 2010; 31: 1112-22.
22. Tobin MC, Moparty B, Farhadi rhadi A, et al. Atopic irritable bowel syndrome: a novel subgroup of irritable bowel syndrome with allergic manifestations. Ann Allergy Asthma Immunol 2008; 100: 49-53.
23. Atkinson W, Sheldon TA, Shaath N et al. Food elimination based on IgG antibodies in irritable bowel syndrome: a randomized controlled trial. Gut 2004; 53: 1459-64. (Pubitemid 39265266)
24. Ventura MT, Polimeno L, Amoruso AC et al. Intestinal permeability in patients with adverse reactions to food. Dig Liver Dis 2006; 38: 726-32.
25. Francis CY, Morris J, Whorwell PJ. The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress. Aliment Pharmacol Ther 1997; 11: 395-402. (Pubitemid 27183522)
26. Bischoff SC, Herrmann A, Manns MP. Prevalence of adverse reactions to food in patients with gastrointestinal disease. Allergy 1996; 51: 811-8. (Pubitemid 26384215)
27. Gwee KA, Leong YL, Graham C et al. The role of psychological and biological factors in postinfective gut dysfunction. Gut 1999; 44: 400-6. (Pubitemid 29119338)
28. Dinan TG, Quigley EM, Ahmed SM et al. Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker? Gastroenterology 2006; 130: 304-11. (Pubitemid 43202030)
29. Bischoff SC, Kramer S. Human mast cells, bacteria, and intestinal immunity. Immunol Rev 2007; 217: 329-37. (Pubitemid 46718156)
30. Klooker TK, Braak B, Koopman KE et al. The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome. Gut 2010; 59: 1213-21.
31. Caughey GH. Tryptase genetics and anaphylaxis. J Allergy Clin Immunol 2006; 117: 1411-4. (Pubitemid 43810215)
32. Stefanini GF, Bazzocchi G, Prati E et al. Efficacy of oral disodium cromoglycate in patients with irritable bowel syndrome and positive skin prick tests to foods. Lancet 1986; 1: 207-8. (Pubitemid 16135530)
33. Lunardi C, Bambara LM, Biasi D, et al. Double-blind cross-over trial of oral sodium cromoglycate in patients with irritable bowel syndrome due to food intolerance. Clin Exp Allergy 1991; 21: 569-72.
34. Roussos A, Koursarakos P, Patsopoulos D et al. Increased prevalence of irritable bowel syndrome in patients with bronchial asthma. Respir Med 2003; 97: 75-9. (Pubitemid 36104903)
35. Sicherer SH, Leung DY. Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2009. J Allergy Clin Immunol 2010; 125: 85-97.
36. Bartra J, Sastre J, del Cuvillo A et al. From pollinosis to digestive allergy. J Investig Allergol Clin Immunol 2009; 19 (Suppl 1): 3-10.
37. Marshall JK, Th abane M, Garg AX et al. Intestinal permeability in patients with irritable bowel syndrome aft er a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario. Aliment Pharmacol Ther 2004; 20: 1317-22. (Pubitemid 40040078)
38. Jensen-Jarolim E, Untersmayr E. Gender-medicine aspects in allergology. Allergy 2008; 63: 610-5. (Pubitemid 351490402)
39. Roka R, Rosztoczy A, Leveque M et al. A pilot study of fecal serine-protease activity: a pathophysiologic factor in diarrhea-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol 2007; 5: 550-5. (Pubitemid 46660764)
40. Aalberse RC. Structural biology of allergens. J Allergy Clin Immunol 2000; 106: 228-38. (Pubitemid 30644995)