Pulmonary haemodynamics in sickle cell disease are driven predominantly by a high-output state rather than elevated pulmonary vascular resistance: A prospective 3-dimensional echocardiography/Doppler study

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Mushemi Blake, Sitali ^a,b   Melikian, Narbeh ^a,b   Drasar, Emma ^b   Bhan, Amit ^b   Lunt, Alan ^b   Desai, Sujal R ^b   Greenough, Anne ^b   Monaghan, Mark J ^a,b   Thein, Swee Lay ^b,c   Shah, Ajay M ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANEMIA; ARTICLE; CARDIOPULMONARY HEMODYNAMICS; CONTROLLED STUDY; DISEASE SEVERITY; DOPPLER ECHOCARDIOGRAPHY; ETHNICITY; FEMALE; GENOTYPE; HEART CATHETERIZATION; HEART LEFT VENTRICLE VOLUME; HEART OUTPUT; HEART VENTRICLE REMODELING; HUMAN; LABORATORY TEST; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; NON INVASIVE PROCEDURE; PREVALENCE; PROSPECTIVE STUDY; PULMONARY HYPERTENSION; SICKLE CELL ANEMIA; THREE DIMENSIONAL ECHOCARDIOGRAPHY; TISSUE DOPPLER IMAGING; TRANSTHORACIC ECHOCARDIOGRAPHY; TRICUSPID VALVE REGURGITATION; COMPLICATION; DIAGNOSTIC IMAGING; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; RISK FACTOR; TRICUSPID VALVE; VASCULAR RESISTANCE; YOUNG ADULT;

ADULT; ANEMIA, SICKLE CELL; CARDIAC OUTPUT; ECHOCARDIOGRAPHY, DOPPLER; ECHOCARDIOGRAPHY, THREE-DIMENSIONAL; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; TRICUSPID VALVE; VASCULAR RESISTANCE; YOUNG ADULT;

EID: 84943173794     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0135472     Document Type: Article

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