Retinal microvascular calibre and risk of diabetes mellitus: a systematic review and participant-level meta-analysis

Diabetologia

Volumn 58, Issue 11, 2015, Pages 2476-2485

  Sabanayagam, Charumathi ^a,b,c   Lye, Weng Kit ^b   Klein, Ronald ^d   Klein, Barbara E K ^d   Cotch, Mary Frances ^e   Wang, Jie Jin ^f   Mitchell, Paul ^f   Shaw, Jonathan E ^g   Selvin, Elizabeth ^h   Sharrett, A Richey ^h   Wong, Tien Y ^a,b,c  

^a SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^e NATIONAL EYE INSTITUTE   (United States)

^f UNIVERSITY OF SYDNEY   (Australia)

^g BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^h JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Cohort studies; Diabetes; Meta analysis; Retinal vessels; Systematic review

Indexed keywords

GLUCOSE;

ARTICLE; COHORT ANALYSIS; DIABETES MELLITUS; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; INCIDENCE; PRIORITY JOURNAL; RETINA BLOOD VESSEL; SEX DIFFERENCE; SYSTEMATIC REVIEW; DIABETES MELLITUS, TYPE 2; FEMALE; MALE; META ANALYSIS; PATHOLOGY; RISK;

DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INCIDENCE; MALE; RETINAL VESSELS; RISK;

EID: 84942990033     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3717-2     Document Type: Article

References (41)

1. International Diabetes Federation (2013) IDF diabetes atlas update 2012. International Diabetes Federation, Brussels
2. Department of Health and Human Services, Centers for Disease Control and Prevention (2012) National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, 2011. Centers for Disease Control and Prevention, Atlanta
3. Clark MG, Barrett EJ, Wallis MG, Vincent MA, Rattigan S (2002) The microvasculature in insulin resistance and type 2 diabetes. Semin Vasc Med 2:21–31
4. Jaap AJ, Shore AC, Tooke JE (1997) Relationship of insulin resistance to microvascular dysfunction in subjects with fasting hyperglycaemia. Diabetologia 40:238–243
5. Clark MG (2008) Impaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle. Am J Physiol Endocrinol Metab 295:E732–E750
6. Vincent MA, Barrett EJ, Lindner JR, Clark MG, Rattigan S (2003) Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin. Am J Physiol Endocrinol Metab 285:E123–E129
7. Struijker-Boudier HA, Heijnen BF, Liu YP, Staessen JA (2012) Phenotyping the microcirculation. Hypertension 60:523–527
8. Struijker-Boudier HA, Rosei AE, Bruneval P et al (2007) Evaluation of the microcirculation in hypertension and cardiovascular disease. Eur Heart J 28:2834–2840
9. Liew G, Wang JJ, Mitchell P, Wong TY (2008) Retinal vascular imaging: a new tool in microvascular disease research. Circ Cardiovasc Imaging 1:156–161
10. Kim JA, Montagnani M, Koh KK, Quon MJ (2006) Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 113:1888–1904
11. Daien V, Carriere I, Kawasaki R et al (2013) Retinal vascular caliber is associated with cardiovascular biomarkers of oxidative stress and inflammation: the POLA study. PLoS One 8, e71089
12. Ikram MK, de Jong FJ, Vingerling JR et al (2004) Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study. Invest Ophthalmol Vis Sci 45:2129–2134
13. Klein R, Klein BE, Knudtson MD, Wong TY, Tsai MY (2006) Are inflammatory factors related to retinal vessel caliber? The Beaver Dam Eye Study. Arch Ophthalmol 124:87–94
14. Wong TY, Islam FM, Klein R et al (2006) Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA). Invest Ophthalmol Vis Sci 47:2341–2350
15. Jeganathan VS, Sabanayagam C, Tai ES et al (2009) Retinal vascular caliber and diabetes in a multiethnic Asian population. Microcirculation 16:534–543
16. Kifley A, Wang JJ, Cugati S, Wong TY, Mitchell P (2007) Retinal vascular caliber, diabetes, and retinopathy. Am J Ophthalmol 143:1024–1026
17. Nguyen TT, Wang JJ, Sharrett AR et al (2008) Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care 31:544–549
18. Cheung CY, Ikram MK, Klein R, Wong TY (2015) The clinical implications of recent studies on the structure and function of the retinal microvasculature in diabetes. Diabetologia 58:871–885
19. Wong TY, Klein R, Sharrett AR et al (2002) Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons. JAMA 287:2528–2533
20. Wong TY, Shankar A, Klein R, Klein BE, Hubbard LD (2005) Retinal arteriolar narrowing, hypertension, and subsequent risk of diabetes mellitus. Arch Intern Med 165:1060–1065
21. Nguyen TT, Wang JJ, Islam FM et al (2008) Retinal arteriolar narrowing predicts incidence of diabetes: the Australian Diabetes, Obesity and Lifestyle (AusDiab) Study. Diabetes 57:536–539
22. Kifley A, Wang JJ, Cugati S, Wong TY, Mitchell P (2008) Retinal vascular caliber and the long-term risk of diabetes and impaired fasting glucose: the Blue Mountains Eye Study. Microcirculation 15:373–377
23. Ikram MK, Janssen JA, Roos AM et al (2006) Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam study. Diabetes 55:506–510
24. Muris DM, Houben AJ, Schram MT, Stehouwer CD (2012) Microvascular dysfunction is associated with a higher incidence of type 2 diabetes mellitus: a systematic review and meta-analysis. Arterioscler Thromb Vasc Biol 32:3082–3094
25. Stroup DF, Berlin JA, Morton SC et al (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 283:2008–2012
26. Muntner P, Woodward M, Mann DM et al (2010) Comparison of the Framingham Heart Study hypertension model with blood pressure alone in the prediction of risk of hypertension: the Multi-Ethnic Study of Atherosclerosis. Hypertension 55:1339–1345
27. Tikellis G, Wang JJ, Tapp R et al (2007) The relationship of retinal vascular calibre to diabetes and retinopathy: the Australian Diabetes, Obesity and Lifestyle (AusDiab) study. Diabetologia 50:2263–2271
28. Hubbard LD, Brothers RJ, King WN et al (1999) Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology 106:2269–2280
29. Knudtson MD, Lee KE, Hubbard LD, Wong TY, Klein R, Klein BE (2003) Revised formulas for summarizing retinal vessel diameters. Curr Eye Res 27:143–149
30. Ikram MK, Sim X, Jensen RA et al (2010) Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet 6, e1001184
31. Wong TY, Knudtson MD, Klein R, Klein BE, Meuer SM, Hubbard LD (2004) Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors. Ophthalmology 111:1183–1190
32. DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177–188
33. Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560
34. Thompson S, Kaptoge S, White I, Wood A, Perry P, Danesh J (2010) Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies. Int J Epidemiol 39:1345–1359
35. Yau JW, Xie J, Lamoureux E et al (2012) Retinal microvascular calibre and risk of incident diabetes: the multi-ethnic study of atherosclerosis. Diabetes Res Clin Pract 95:265–274
36. Clark MG, Wallis MG, Barrett EJ et al (2003) Blood flow and muscle metabolism: a focus on insulin action. Am J Physiol Endocrinol Metab 284:E241–E258
37. Youd JM, Rattigan S, Clark MG (2000) Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-α. Diabetes 49:1904–1909
38. Balletshofer BM, Rittig K, Enderle MD et al (2000) Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance. Circulation 101:1780–1784
39. Cornes BK, Brody JA, Nikpoor N et al (2014) Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet 7:374–382
40. Chen P, Takeuchi F, Lee JY et al (2014) Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians. Diabetes 63:2551–2562
41. Schneider AL, Pankow JS, Heiss G, Selvin E (2012) Validity and reliability of self-reported diabetes in the atherosclerosis risk in communities study. Am J Epidemiol 176:738–743