A Comprehensive Proteomics Analysis Reveals a Secretory Path- and Status-Dependent Signature of Exosomes Released from Tumor-Associated Macrophages

Journal of Proteome Research

Volumn 14, Issue 10, 2015, Pages 4319-4331

  Zhu, Yinghui ^a,b   Chen, Xianwei ^a,b   Pan, Qingfei ^a,b   Wang, Yang ^a,b   Su, Siyuan ^a,b   Jiang, Cuicui ^c   Li, Yang ^c   Xu, Ningzhi ^d   Wu, Lin ^a   Lou, Xiaomin ^a   Liu, Siqi ^a  

^a Chinese Academy of Sciences and China National Center for Bioinformation   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c and Laboratory of Aerospace Servo Actuation and Transmission   (China)

^d PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

exosome; iTRAQ; proteasome; protein signature; ribosome; tumor associated macrophage

Indexed keywords

ATP SYNTHASE SUBUNIT ALPHA; CATHEPSIN D; COMPLEMENT COMPONENT C3; EH DOMAIN CONTAINING PROTEIN 1; FORMYLGLUTATHIONE HYDROLASE; GRANULIN; MACROPHAGE ELASTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE KINASE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PHOSPHOLIPASE A1 MEMBRANE A; PROSAPOSIN; PROTEASOME; PROTEASOME SUBUNIT ALPHA TYPE 1; PROTEASOME SUBUNIT ALPHA TYPE 2; PROTEASOME SUBUNIT ALPHA TYPE 4; PROTEASOME SUBUNIT ALPHA TYPE 6; PROTEASOME SUBUNIT BETA TYPE 2; PROTEASOME SUBUNIT BETA TYPE 3; PROTEASOME SUBUNIT BETA TYPE 4; PROTEASOME SUBUNIT BETA TYPE 6; PROTEASOME SUBUNIT BETA TYPE 8; PROTEIN; PROTEOME; RIBOSOME PROTEIN; RNA; SEQUESTOSOME 1; THROMBOSPONDIN 1; TRANSMEMBRANE GLYCOPROTEIN NMB; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE GLUCOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; VALOSIN CONTAINING PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN RNA BINDING; PROTEOMICS; RNA PROCESSING; SECRETORY PATHWAY; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; ANIMAL; CELL COMMUNICATION; CHEMISTRY; COLORECTAL TUMOR; ENZYME ASSAY; GENETICS; ISOLATION AND PURIFICATION; MACROPHAGE; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PROCEDURES; TANDEM MASS SPECTROMETRY; TUMOR CELL LINE;

ANIMALS; CELL COMMUNICATION; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; ENZYME ASSAYS; EXOSOMES; MACROPHAGES; MICE; MOLECULAR SEQUENCE ANNOTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTEOME; PROTEOMICS; RIBOSOMAL PROTEINS; RNA PROCESSING, POST-TRANSCRIPTIONAL; TANDEM MASS SPECTROMETRY; TUMOR MICROENVIRONMENT;

EID: 84942931451     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00770     Document Type: Article

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