Combination treatment with all-trans retinoic acid prevents cisplatin-induced enrichment of CD133+ tumor-initiating cells and reveals heterogeneity of cancer stem cell compartment in lung cancer

Journal of Thoracic Oncology

Volumn 10, Issue 7, 2015, Pages 1027-1036

  Moro, Massimo ^a   Bertolini, Giulia ^a   Pastorino, Ugo ^a   Roz, Luca ^a   Sozzi, Gabriella ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Cancer stem cells dynamics; Cisplatin resistance; Non small cell lung cancer; Retinoic acid

Indexed keywords

CD133 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CISPLATIN; RETINOIC ACID; ANTINEOPLASTIC AGENT; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE; PROM1 PROTEIN, HUMAN; PROM1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER RECURRENCE; CANCER RESISTANCE; CANCER STEM CELL; CELL COMPARTMENTALIZATION; CELL FATE; CELL HETEROGENEITY; CELL SUBPOPULATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; METASTASIS; NON SMALL CELL LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TUMOR INITIATING CELL; TUMOR XENOGRAFT; ADENOCARCINOMA; AGED; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; LUNG NEOPLASMS; MALE; METABOLISM; MOUSE; PATHOLOGY; RANDOMIZATION; SCID MOUSE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AC133 ANTIGEN; ADENOCARCINOMA; AGED; ANIMALS; ANTIGENS, CD; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINE, TUMOR; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FEMALE; GLYCOPROTEINS; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, SCID; NEOPLASTIC STEM CELLS; PEPTIDES; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; TRETINOIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84942915226     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0000000000000563     Document Type: Article

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