All-trans retinoic acid potentiates the chemotherapeutic effect of cisplatin by inducing differentiation of tumor initiating cells in liver cancer

Journal of Hepatology

Volumn 59, Issue 6, 2013, Pages 1255-1263

  Zhang, Yang ^a   Guan, Dong Xian ^b   Shi, Jie ^a   Gao, Hong ^b   Li, Jing Jing ^b   Zhao, Jiang Sha ^b   Qiu, Lin ^b   Liu, Jiang ^b   Li, Nan ^a   Guo, Wei Xing ^a   Xue, Jie ^a   Zhou, Fei Guo ^a   Wu, Meng Chao ^a   Wang, Hong Yang ^a   Xie, Dong ^b,c   Cheng, Shu Qun ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^c BEIJING HOSPITAL   (China)

Author keywords

Apoptosis; ATRA; Chemo sensitivity; Cisplatin; Differentiation; Hepatocellular carcinoma; Metastasis; Tumor initiating cell

Indexed keywords

CD133 ANTIGEN; CD24 ANTIGEN; CISPLATIN; EPITHELIAL CELL ADHESION MOLECULE; MESSENGER RNA; PROTEIN KINASE B; RETINOIC ACID; THY 1 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER SIZE; CARCINOGENICITY; CELL COUNT; CELL DIFFERENTIATION; CELL GROWTH; CELL MIGRATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENTIATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; LIVER METASTASIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AKT; ALL-TRANS RETINOIC ACID; APOPTOSIS; ATRA; CHEMO-SENSITIVITY; CIS-DIAMMINEPLATINUM (II); CISPLATIN; DIFFERENTIATION; DIMETHYL SURFOXIDE; DMSO; EPCAM; EPITHELIAL CELL ADHESION MOLECULE; FACS; FLUORESCENCE ACTIVATED CELL SORTING; HCC; HEPATOCELLULAR CARCINOMA; METASTASIS; PROTEIN KINASE B; TIC; TUMOR INITIATING CELL;

ANIMALS; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CISPLATIN; DRUG SYNERGISM; HUMANS; LIVER NEOPLASMS; MALE; MICE; NEOPLASTIC STEM CELLS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; TRETINOIN;

EID: 84888016054     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.07.009     Document Type: Article

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