메뉴 건너뛰기




Volumn 75, Issue 16, 2015, Pages 3268-3278

Tumors escape CD4+ T-cell-mediated immunosurveillance by impairing the ability of infiltrating macrophages to indirectly present tumor antigens

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN LIGHT CHAIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN;

EID: 84942896216     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-3640     Document Type: Article
Times cited : (23)

References (43)
  • 2
    • 0033991158 scopus 로고    scopus 로고
    • Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
    • Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv Immunol 2000;74:181-273.
    • (2000) Adv Immunol , vol.74 , pp. 181-273
    • Marincola, F.M.1    Jaffee, E.M.2    Hicklin, D.J.3    Ferrone, S.4
  • 3
    • 84863594742 scopus 로고    scopus 로고
    • Cellular constituents of immune escape within the tumor microenvironment
    • Kerkar SP, Restifo NP. Cellular constituents of immune escape within the tumor microenvironment. Cancer Res 2012;72:3125-30.
    • (2012) Cancer Res , vol.72 , pp. 3125-3130
    • Kerkar, S.P.1    Restifo, N.P.2
  • 5
    • 20044363610 scopus 로고    scopus 로고
    • + T helper cells and hindered by naturally occurring T regulatory cells
    • Antony PA, Piccirillo CA, Akpinarli A, Finkelstein SE, Speiss PJ, Surman DR, et al. CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells. J Immunol 2005;174:2591-601.
    • (2005) J Immunol , vol.174 , pp. 2591-2601
    • Antony, P.A.1    Piccirillo, C.A.2    Akpinarli, A.3    Finkelstein, S.E.4    Speiss, P.J.5    Surman, D.R.6
  • 6
    • 0037112446 scopus 로고    scopus 로고
    • Antigen-specific CD4(+) T-cell help is required to activate a memory CD8(+) T cell to a fully functional tumor killer cell
    • Gao FG, Khammanivong V, Liu WJ, Leggatt GR, Frazer IH, Fernando GJP. Antigen-specific CD4(+) T-cell help is required to activate a memory CD8(+) T cell to a fully functional tumor killer cell. Cancer Res 2002;62:6438-41.
    • (2002) Cancer Res , vol.62 , pp. 6438-6441
    • Gao, F.G.1    Khammanivong, V.2    Liu, W.J.3    Leggatt, G.R.4    Frazer, I.H.5    Gjp, F.6
  • 7
    • 0028337547 scopus 로고
    • Naive idiotype-specific CD4+ T cells and immunosurveillance of B-cell tumors
    • Lauritzsen GF, Weiss S, Dembic Z, Bogen B. Naive idiotype-specific CD4+ T cells and immunosurveillance of B-cell tumors. Proc Natl Acad Sci U S A 1994;91:5700-4.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5700-5704
    • Lauritzsen, G.F.1    Weiss, S.2    Dembic, Z.3    Bogen, B.4
  • 8
    • 77949530108 scopus 로고    scopus 로고
    • Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma
    • Xie Y, Akpinarli A, Maris C, Hipkiss EL, Lane M, Kwon EK, et al. Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma. J Exp Med 2010;207:651-67.
    • (2010) J Exp Med , vol.207 , pp. 651-667
    • Xie, Y.1    Akpinarli, A.2    Maris, C.3    Hipkiss, E.L.4    Lane, M.5    Kwon, E.K.6
  • 9
    • 77949522803 scopus 로고    scopus 로고
    • + T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
    • Quezada SA, Simpson TR, Peggs KS, Merghoub T, Vider J, Fan X, et al. Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J Exp Med 2010;207:637-50.
    • (2010) J Exp Med , vol.207 , pp. 637-650
    • Quezada, S.A.1    Simpson, T.R.2    Peggs, K.S.3    Merghoub, T.4    Vider, J.5    Fan, X.6
  • 10
    • 0033662405 scopus 로고    scopus 로고
    • CD4(+) T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells
    • Qin ZH, Blankenstein T. CD4(+) T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells. Immunity 2000; 12:677-86.
    • (2000) Immunity , vol.12 , pp. 677-686
    • Qin, Z.H.1    Blankenstein, T.2
  • 11
    • 84900301377 scopus 로고    scopus 로고
    • + T cells in a patient with epithelial cancer
    • Tran E, Turcotte S, Gros A, Robbins PF, Lu YC, Dudley ME, et al. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer. Science 2014;344:641-5.
    • (2014) Science , vol.344 , pp. 641-645
    • Tran, E.1    Turcotte, S.2    Gros, A.3    Robbins, P.F.4    Lu, Y.C.5    Dudley, M.E.6
  • 13
    • 8644232490 scopus 로고    scopus 로고
    • + T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo
    • Lundin KU, Screpanti V, Omholt H, Hofgaard PO, Yagita H, Grandien A, et al. CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo. Cancer Immunol Immunother 2004;53:1135-45.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 1135-1145
    • Lundin, K.U.1    Screpanti, V.2    Omholt, H.3    Hofgaard, P.O.4    Yagita, H.5    Grandien, A.6
  • 15
    • 0028803330 scopus 로고
    • + T cells confer idiotype-specific tumor resistance in the absence of antibodies
    • Bogen B, Munthe L, Sollien A, Hofgaard P, Omholt H, Dagnaes F, et al. Naive CD4+ T cells confer idiotype-specific tumor resistance in the absence of antibodies. Eur J Immunol 1995;25:3079-86.
    • (1995) Eur J Immunol , vol.25 , pp. 3079-3086
    • Bogen, B.1    Munthe, L.2    Sollien, A.3    Hofgaard, P.4    Omholt, H.5    Dagnaes, F.6
  • 17
    • 0034646266 scopus 로고    scopus 로고
    • + T cells
    • Dembic Z, Schenck K, Bogen B. Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells. Proc Natl Acad Sci U S A 2000;97:2697-702.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2697-2702
    • Dembic, Z.1    Schenck, K.2    Bogen, B.3
  • 20
    • 0023032941 scopus 로고
    • Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules
    • Bogen B, Malissen B, Haas W. Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules. Eur J Immunol 1986;16:1373-8.
    • (1986) Eur J Immunol , vol.16 , pp. 1373-1378
    • Bogen, B.1    Malissen, B.2    Haas, W.3
  • 21
    • 0026586688 scopus 로고
    • Weak positive selection of transgenic T cell receptor-bearing thymocytes: Importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities
    • Bogen B, Gleditsch L, Weiss S, Dembic Z. Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities. Eur J Immunol 1992;22:703-9.
    • (1992) Eur J Immunol , vol.22 , pp. 703-709
    • Bogen, B.1    Gleditsch, L.2    Weiss, S.3    Dembic, Z.4
  • 22
    • 84907821781 scopus 로고    scopus 로고
    • + T-cell-mediated elimination of MHC II(NEG) tumor cells is spatially restricted and fails to prevent escape of antigen-negative cells
    • Tveita AA, Schjesvold FH, Sundnes O, Haabeth OA, Haraldsen G, Bogen B. Indirect CD4+ T-cell-mediated elimination of MHC II(NEG) tumor cells is spatially restricted and fails to prevent escape of antigen-negative cells. Eur J Immunol 2014;44:2625-37.
    • (2014) Eur J Immunol , vol.44 , pp. 2625-2637
    • Tveita, A.A.1    Schjesvold, F.H.2    Sundnes, O.3    Haabeth, O.A.4    Haraldsen, G.5    Bogen, B.6
  • 23
    • 0030972407 scopus 로고    scopus 로고
    • Versatile vectors for transient and stable expression of recombinant antibody molecules in mammalian cells
    • Norderhaug L, Olafsen T, Michaelsen TE, Sandlie I. Versatile vectors for transient and stable expression of recombinant antibody molecules in mammalian cells. J Immunol Methods 1997;204:77-87.
    • (1997) J Immunol Methods , vol.204 , pp. 77-87
    • Norderhaug, L.1    Olafsen, T.2    Michaelsen, T.E.3    Sandlie, I.4
  • 24
    • 0026031205 scopus 로고
    • MHC class II-restricted presentation of intracellular antigen
    • Weiss S, Bogen B. MHC class II-restricted presentation of intracellular antigen. Cell 1991;64:767-76.
    • (1991) Cell , vol.64 , pp. 767-776
    • Weiss, S.1    Bogen, B.2
  • 25
    • 0027299121 scopus 로고
    • + T cells in tumor resistance against major histocompatibility complex class II molecule negative plasmacytoma cells
    • Lauritzsen GF, Bogen B. The role of idiotype-specific, CD4+ T cells in tumor resistance against major histocompatibility complex class II molecule negative plasmacytoma cells. Cell Immunol 1993;148: 177-88.
    • (1993) Cell Immunol , vol.148 , pp. 177-188
    • Lauritzsen, G.F.1    Bogen, B.2
  • 26
    • 0021792297 scopus 로고
    • T helper cell recognition of idiotopes on l2 light chains ofM315 and T952: Evidence for dependence on somatic mutations in the third hypervariable region
    • Bogen B, Jørgensen T, Hannestad K. T helper cell recognition of idiotopes on l2 light chains ofM315 and T952: evidence for dependence on somatic mutations in the third hypervariable region. Eur J Immunol 1985;15: 278-81.
    • (1985) Eur J Immunol , vol.15 , pp. 278-281
    • Bogen, B.1    Jørgensen, T.2    Hannestad, K.3
  • 27
    • 0023499611 scopus 로고
    • Two M315 idiotopes defined by isologous monoclonal antibodies: One depends on germline and the other on mutated murine lambda 2 light chain sequences
    • Kristoffersen G, Hannestad K, Hansen T. Two M315 idiotopes defined by isologous monoclonal antibodies: one depends on germline and the other on mutated murine lambda 2 light chain sequences. Scand J Immunol 1987;26:535-46.
    • (1987) Scand J Immunol , vol.26 , pp. 535-546
    • Kristoffersen, G.1    Hannestad, K.2    Hansen, T.3
  • 28
    • 84865828041 scopus 로고    scopus 로고
    • SDS-PAGE for (3)(5)S immunoprecipitation and immunoprecipitation western blotting
    • Trieu EP, Targoff IN. SDS-PAGE for (3)(5)S immunoprecipitation and immunoprecipitation western blotting. Methods Mol Biol 2012;869: 215-33.
    • (2012) Methods Mol Biol , vol.869 , pp. 215-233
    • Trieu, E.P.1    Targoff, I.N.2
  • 29
    • 84902105413 scopus 로고    scopus 로고
    • Assessing the citrullinome in rheumatoid arthritis synovial fluid with and without enrichment of citrullinated peptides
    • Tutturen AE, Fleckenstein B, de Souza GA. Assessing the citrullinome in rheumatoid arthritis synovial fluid with and without enrichment of citrullinated peptides. J Proteome Res 2014;13:2867-73.
    • (2014) J Proteome Res , vol.13 , pp. 2867-2873
    • Tutturen, A.E.1    Fleckenstein, B.2    De Souza, G.A.3
  • 30
    • 0030265732 scopus 로고    scopus 로고
    • Ig light chains are secreted predominantly as monomers
    • Dul JL, Aviel S, Melnick J, Argon Y. Ig light chains are secreted predominantly as monomers. J Immunol 1996;157:2969-75.
    • (1996) J Immunol , vol.157 , pp. 2969-2975
    • Dul, J.L.1    Aviel, S.2    Melnick, J.3    Argon, Y.4
  • 31
    • 0018820821 scopus 로고
    • Structural mutations in a mouse immunoglobulin light chain resulting in failure to be secreted
    • Mosmann TR, Williamson AR. Structural mutations in a mouse immunoglobulin light chain resulting in failure to be secreted. Cell 1980;20: 283-92.
    • (1980) Cell , vol.20 , pp. 283-292
    • Mosmann, T.R.1    Williamson, A.R.2
  • 32
    • 0020641571 scopus 로고
    • Secretion of a lambda 2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region
    • Wu GE, Hozumi N, Murialdo H. Secretion of a lambda 2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region. Cell 1983;33:77-83.
    • (1983) Cell , vol.33 , pp. 77-83
    • Wu, G.E.1    Hozumi, N.2    Murialdo, H.3
  • 33
    • 0020470810 scopus 로고
    • Requirements for the processing of antigen by antigen-presenting B cells. II. Biochemical comparison of the fate of antigen in B cell tumors and macrophages
    • Grey HM, Colon SM, Chesnut RW. Requirements for the processing of antigen by antigen-presenting B cells. II. Biochemical comparison of the fate of antigen in B cell tumors and macrophages. J Immunol 1982;129: 2389-95.
    • (1982) J Immunol , vol.129 , pp. 2389-2395
    • Grey, H.M.1    Colon, S.M.2    Chesnut, R.W.3
  • 34
    • 0023573995 scopus 로고
    • Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin A loop-specific T cells
    • Naquet P, Ellis J, Singh B, Hodges RS, Delovitch TL. Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin A loop-specific T cells. J Immunol 1987;139: 3955-63.
    • (1987) J Immunol , vol.139 , pp. 3955-3963
    • Naquet, P.1    Ellis, J.2    Singh, B.3    Hodges, R.S.4    Delovitch, T.L.5
  • 35
    • 0011203929 scopus 로고
    • T cells specific for alpha-beta interface regions of hemoglobin recognize the isolated subunit but not the tetramer and indicate presentation without processing
    • AtassiMZ, Yoshioka M, Bixler GS Jr. T cells specific for alpha-beta interface regions of hemoglobin recognize the isolated subunit but not the tetramer and indicate presentation without processing. Proc Natl Acad Sci U S A 1989;86:6729-33.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 6729-6733
    • Atassimz Yoshioka, M.1    Bixler, G.S.2
  • 36
    • 0024598687 scopus 로고
    • Conformation-dependent recognition of a protein by T cells requires presentation without processing
    • Atassi MZ, Bixler GS Jr, Yokoi T. Conformation-dependent recognition of a protein by T cells requires presentation without processing. Biochem J 1989;259:731-5.
    • (1989) Biochem J , vol.259 , pp. 731-735
    • Atassi, M.Z.1    Bixler, G.S.2    Yokoi, T.3
  • 38
    • 0019188771 scopus 로고
    • Immunoglobulin chain loss in hybridoma lines
    • Kohler G. Immunoglobulin chain loss in hybridoma lines. Proc Natl Acad Sci U S A 1980;77:2197-9.
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 2197-2199
    • Kohler, G.1
  • 39
    • 0018973063 scopus 로고
    • Analysis of immunoglobulin chain secretion using hybrid myelomas
    • Wilde CD, Milstein C. Analysis of immunoglobulin chain secretion using hybrid myelomas. Eur J Immunol 1980;10:462-7.
    • (1980) Eur J Immunol , vol.10 , pp. 462-467
    • Wilde, C.D.1    Milstein, C.2
  • 40
    • 84883535208 scopus 로고    scopus 로고
    • The role of endoplasmic reticulum stress in maintaining and targeting multiple myeloma: A double-edged sword of adaptation and apoptosis
    • White-Gilbertson S, Hua Y, Liu B. The role of endoplasmic reticulum stress in maintaining and targeting multiple myeloma: a double-edged sword of adaptation and apoptosis. Front Genet 2013; 4:109.
    • (2013) Front Genet , vol.4 , pp. 109
    • White-Gilbertson, S.1    Hua, Y.2    Liu, B.3
  • 41
    • 2342506448 scopus 로고    scopus 로고
    • Light-chain only multiple myeloma is due to the absence of functional (productive) rearrangement of the IgH gene at the DNA level
    • Magrangeas F, Cormier ML, Descamps G, Gouy N, Lode L, Mellerin MP, et al. Light-chain only multiple myeloma is due to the absence of functional (productive) rearrangement of the IgH gene at the DNA level. Blood 2004;103:3869-75.
    • (2004) Blood , vol.103 , pp. 3869-3875
    • Magrangeas, F.1    Cormier, M.L.2    Descamps, G.3    Gouy, N.4    Lode, L.5    Mellerin, M.P.6
  • 42
    • 84901717964 scopus 로고    scopus 로고
    • Serum free light chain evaluation as a marker for the impact of intra-clonal heterogeneity on the progression and treatment resistance in multiple myeloma
    • Brioli A, Giles H, Pawlyn C, Campbell JP, KaiserMF, Melchor L, et al. Serum free light chain evaluation as a marker for the impact of intra-clonal heterogeneity on the progression and treatment resistance in multiple myeloma. Blood 2014;123:3414-9.
    • (2014) Blood , vol.123 , pp. 3414-3419
    • Brioli, A.1    Giles, H.2    Pawlyn, C.3    Campbell, J.P.4    Kaisermf Melchor, L.5
  • 43
    • 59449099228 scopus 로고    scopus 로고
    • Light-chain escape-multiple myeloma'-an escape phenomenon from plateau phase: Report of the largest patient series using LC-monitoring
    • Kuhnemund A, Liebisch P, Bauchmuller K, zur Hausen A, Veelken H, Wasch R, et al. 'Light-chain escape-multiple myeloma'-an escape phenomenon from plateau phase: report of the largest patient series using LC-monitoring. J Cancer Res Clin Oncol 2009;135:477-84.
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 477-484
    • Kuhnemund, A.1    Liebisch, P.2    Bauchmuller, K.3    Zur Hausen, A.4    Veelken, H.5    Wasch, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.