Cystic echinococcosis therapy: Albendazole-loaded lipid nanocapsules enhance the oral bioavailability and efficacy in experimentally infected mice

Acta Tropica

Volumn 152, Issue , 2015, Pages 185-194

  Pensel, Patricia E ^a,b   Ullio Gamboa, Gabriela ^b,c   Fabbri, Julia ^a,b   Ceballos, Laura ^d   Sanchez Bruni, Sergio ^d   Alvarez, Luis I ^d   Allemandi, Daniel ^b,c   Benoit, Jean Pierre ^e   Palma, Santiago D ^b,c   Elissondo, María C ^a,b  

^a UNIVERSIDAD NACIONAL DE MAR DEL PLATA   (Argentina)

^b Consejo Nacional de Investigaciones Científicas y Técnicas ^*  (Argentina)

^c UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^d UNIVERSIDAD NACIONAL DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES   (Argentina)

^e UNIVERSITÉ D'ANGERS   (France)

Author keywords

Albendazole; Cystic echinococcosis; Echinococcus granulosus; Lipid nanocapsules

Indexed keywords

ALBENDAZOLE; LIPID NANOCAPSULE; NANOCAPSULE; UNCLASSIFIED DRUG; ANTHELMINTIC AGENT; LIPID;

BIOAVAILABILITY; CONCENTRATION (COMPOSITION); DRUG; LIPID; MEDICAL GEOGRAPHY; PARASITIC DISEASE; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG EXPOSURE; DRUG FORMULATION; ECHINOCOCCOSIS; FEMALE; IN VITRO STUDY; MAXIMUM PLASMA CONCENTRATION; MOUSE; NANOENCAPSULATION; NONHUMAN; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; BIOAVAILABILITY; DRUG DELIVERY SYSTEM; ECHINOCOCCUS GRANULOSUS; MEDICINAL CHEMISTRY; ORAL DRUG ADMINISTRATION;

ANIMALIA; ECHINOCOCCUS GRANULOSUS; MUS;

ADMINISTRATION, ORAL; ALBENDAZOLE; ANIMALS; ANTHELMINTICS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; ECHINOCOCCOSIS; ECHINOCOCCUS GRANULOSUS; FEMALE; LIPIDS; MICE; NANOCAPSULES;

EID: 84942882073     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2015.09.016     Document Type: Article

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