Temporal release pattern of copeptin and troponin t in patients with suspected acute coronary syndrome and spontaneous acute myocardial infarction

Clinical Chemistry

Volumn 61, Issue 10, 2015, Pages 1273-1282

  Slagman, Anna ^a   Searle, Julia ^a   Müller, Christian ^a   Möckel, Martin ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; COPEPTIN; HEPARIN; TROPONIN T; GLYCOPEPTIDE;

ACUTE CORONARY SYNDROME; ACUTE HEART INFARCTION; ADULT; AGED; AMBULANCE; AMBULANCE TRANSPORTATION; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HEART INFARCTION; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; PERCUTANEOUS CORONARY INTERVENTION; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; UNSTABLE ANGINA PECTORIS; ANGINA, UNSTABLE; BLOOD; MIDDLE AGED; MYOCARDIAL INFARCTION; PROGNOSIS; PROSPECTIVE STUDY;

ACUTE CORONARY SYNDROME; AGED; ANGINA, UNSTABLE; BIOMARKERS; FEMALE; GLYCOPEPTIDES; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; ROC CURVE; TROPONIN T;

EID: 84942876868     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2015.240580     Document Type: Article

References (29)

1. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD, et al. Third universal definition of myocardial infarction. Eur Heart J 2012;33:2551-67.
2. Hamm CW, Bassand JP, Agewall S, Bax J, Boersma E, Bueno H, et al. ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2011;32:2999-3054.
3. Morgenthaler NG. Copeptin: a biomarker of cardiovascular and renal function. Congest Heart Fail 2010; 16(Suppl 1):S37- 44.
4. Reichlin T, Hochholzer W, Stelzig C, Laule K, Freidank H, Morgenthaler NG, et al. Incremental value of copeptin for rapid rule out of acute myocardial infarction. J Am Coll Cardiol 2009;54:60-8.
5. Giannitsis E, Kehayova T, Vafaie M, Katus HA. Combined testing of high-sensitivity troponin T and copeptin on presentation at prespecified cutoffs improves rapid rule-out of non-ST-segment elevation myocardial infarction. Clin Chem 2011;57:1452-5.
6. Keller T, Tzikas S, Zeller T, Czyz E, Lillpopp L, Ojeda FM, et al. Copeptin improves early diagnosis of acute myocardial infarction. J Am Coll Cardiol 2010;55: 2096-106.
7. Meune C, Zuily S, Wahbi K, Claessens YE, Weber S, Chenevier-Gobeaux C. Combination of copeptin and high-sensitivity cardiac troponin T assay in unstable angina and non-ST-segment elevation myocardial infarction: a pilot study. Arch Cardiovasc Dis 2011;104: 4-10.
8. Collinson P, Gaze D, Goodacre S. Comparison of contemporary troponin assays with the novel biomarkers, heart fatty acid binding protein and copeptin, for the early confirmation or exclusion of myocardial infarction in patients presenting to the emergency department with chest pain. Heart 2014;100:140-5.
9. Eggers KM, Venge P, Lindahl B. High-sensitive cardiac troponin T outperforms novel diagnostic biomarkers in patients with acute chest pain. Clin Chim Acta 2012; 413:1135-40.
10. Maisel A, Mueller C, Neath SX, Christenson RH, Morgenthaler NG, McCord J, et al. Copeptin helps in the early detection of patients with acute myocardial infarction: primary results of the CHOPIN trial (Copeptin Helps in the early detection Of Patients with acute myocardial INfarction). J Am Coll Cardiol 2013;62: 150-60.
11. Sukul D, Bonaca MP, Ruff CT, Kosowsky J, Conrad M, Murphy SA, et al. Diagnostic performance of copeptin in patients with acute nontraumatic chest pain: BWHTIMI ED chest pain study. Clin Cardiol 2014;37:227-32.
12. Gu YL, Voors AA, Zijlstra F, Hillege HL, Struck J, Masson S, et al. Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction. Clin Res Cardiol 2011;100:1069-76.
13. Liebetrau C, Nef H, Szardien S, Dorr O, Willmer M, Voss S, et al. Release kinetics of copeptin in patients undergoing transcoronary ablation of septal hypertrophy. Clin Chem 2013;59:566-9.
14. Mockel M, Searle J, Hamm C, Slagman A, Blankenberg S, Huber K, et al. Early discharge using single cardiac troponin and copeptin testing in patients with suspected acute coronary syndrome (ACS): a randomized, controlled clinical process study. Eur Heart J 2015;36: 369-76.
15. Giannitsis E, Kurz K, Hallermayer K, Jarausch J, Jaffe AS, Katus HA. Analytical validation of a high-sensitivity cardiac troponin T assay. Clin Chem 2010;56:254-61.
16. Apple FS, Collinson PO, IFCC Task Force on Clinical Applications of Cardiac Biomarkers. Analytical characteristics of high-sensitivity cardiac troponin assays. Clin Chem 2012;58:54-61.
17. Bahrmann P, Bahrmann A, Breithardt OA, Daniel WG, Christ M, Sieber CC, Bertsch T. Additional diagnostic and prognostic value of copeptin ultra-sensitive for diagnosis of non-ST-elevation myocardial infarction in older patients presenting to the emergency department. Clin Chem Lab Med 2013;51:1307-19.
18. Charpentier S, Lepage B, Maupas-Schwalm F, Cinq- Frais C, Bichard-Breaud M, Botella JM, et al. Copeptin improves the diagnostic performance of sensitive troponin I-ultra but cannot rapidly rule out non-ST-elevation myocardial infarction at presentation to an emergency department. Ann Emerg Med 2013;61: 549 -58.e1.
19. Folli C, Consonni D, Spessot M, Salvini L, Velati M, Ranzani G, et al. Diagnostic role of copeptin in patients presenting with chest pain in the emergency room. Euro J Intern Med 2013;24:189-93.
20. Llorens P, Sanchez M, Herrero P, Martin-Sanchez FJ, Pinera P, Miro O, COPED Study Investigators. The utility of copeptin in the emergency department for non-ST-elevation myocardial infarction rapid rule out: COPEDMIRRO study. Eur J Emerg Med 2014;21:220-9.
21. Lotze U, Lemm H, Heyer A, Muller K. Combined determination of highly sensitive troponin T and copeptin for early exclusion of acute myocardial infarction: first experience in an emergency department of a general hospital. Vasc Health Risk Manag 2011;7:509-15.
22. Potocki M, Reichlin T, Thalmann S, Zellweger C, Twerenbold R, Reiter M, et al. Diagnostic and prognostic impact of copeptin and high-sensitivity cardiac troponin T in patients with pre-existing coronary artery disease and suspected acute myocardial infarction. Heart 2012;98:558-65.
23. Sebbane M, Lefebvre S, Kuster N, Jreige R, Jacques E, Badiou S, et al. Early rule out of acute myocardial infarction in ED patients: value of combined high-sensitivity cardiac troponin T and ultrasensitive copeptin assays at admission. Am J Emerg Med 2013;31:1302-8.
24. Mockel M, Searle J. The positive predictive value of CtproAVP (copeptin) in patients with STEMI. Heart 2013;99:1475.
25. Reinstadler SJ, Klug G, Feistritzer HJ, Mayr A, Harrasser B, Mair J, et al. Association of copeptin with myocardial infarct size and myocardial function after ST segment elevation myocardial infarction. Heart 2013;99: 1525-9.
26. Hupf H, Grimm D, Riegger GA, Schunkert H. Evidence for a vasopressin system in the rat heart. Circ Res 1999; 84:365-70.
27. Lipinski MJ, Escarcega RO, D'Ascenzo F, Magalhaes MA, Baker NC, Torguson R, et al. A systematic review and collaborative meta-analysis to determine the incremental value of copeptin for rapid rule-out of acute myocardial infarction. Am J Cardiol 2014;113:1581-91.
28. Raskovalova T, Twerenbold R, Collinson PO, Keller T, Bouvaist H, Folli C, et al. Diagnostic accuracy of combined cardiac troponin and copeptin assessment for early rule-out of myocardial infarction: a systematic review and meta-analysis. Eur Heart J Acute Cardiovasc Care 2014;3:18-27.
29. Morgenthaler NG, Struck J, Alonso C, Bergmann A. Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin. Clin Chem 2006;52:112-9.