Copeptin helps in the early detection of patients with acute myocardial infarction: Primary results of the CHOPIN trial (Copeptin Helps in the early detection of Patients with acute myocardial INfarction)

Journal of the American College of Cardiology

Volumn 62, Issue 2, 2013, Pages 150-160

  Maisel, Alan ^a,b   Mueller, Christian ^c   Neath, Sean Xavier ^b   Christenson, Robert H ^d   Morgenthaler, Nils G ^e   McCord, James ^f   Nowak, Richard M ^f   Vilke, Gary ^b   Daniels, Lori B ^b   Hollander, Judd E ^g   Apple, Fred S ^h   Cannon, Chad ⁱ   Nagurney, John T ^j   Schreiber, Donald ^k   Defilippi, Christopher ^d   Hogan, Christopher ^l   Diercks, Deborah B ^m   Stein, John C ⁿ   Headden, Gary ^o   Limkakeng, Alexander T ^p   Anand, Inder ^q   Wu, Alan H B ⁿ   Papassotiriou, Jana ^r   Hartmann, Oliver ^r   Ebmeyer, Stefan ^r   Clopton, Paul ^a   Jaffe, Allan S ^s   Peacock, W Frank ^t   more..

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY HOSPITAL BASEL   (Switzerland)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^f HENRY FORD HEALTH SYSTEM   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h HENNEPIN COUNTY MEDICAL CENTER   (United States)

ⁱ UNIVERSITY OF KANSAS HOSPITAL   (United States)

^j MASSACHUSETTS GENERAL HOSPITAL   (United States)

^k STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^m UNIVERSITY OF CALIFORNIA   (United States)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^p DUKE UNIVERSITY MEDICAL CENTER   (United States)

^q Minneapolis VA Center   (United States)

^r THERMO FISHER SCIENTIFIC   (Germany)

^s MAYO CLINIC   (United States)

^t BAYLOR COLLEGE OF MEDICINE   (United States)

more..

Author keywords

copeptin; emergency department; myocardial infarction; quality improvement; troponin

Indexed keywords

COPEPTIN; TROPONIN I;

ACUTE CORONARY SYNDROME; ACUTE HEART INFARCTION; ADULT; ARTICLE; CAUSE OF DEATH; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE DURATION; EARLY DIAGNOSIS; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW UP; HORMONE BLOOD LEVEL; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THORAX PAIN;

EID: 84879828614     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.04.011     Document Type: Article

References (25)

1. R. Bingisser, C. Cairns, and M. Christ Cardiac troponin: a critical review of the case for point-of-care testing in the ED Am J Emerg Med 30 2012 1639 1649
2. N.G. Morgenthaler, J. Struck, C. Alonso, and A. Bergmann Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin Clin Chem 52 2006 112 119
3. C.H. Nickel, R. Bingisser, and N.G. Morgenthaler The role of copeptin as a diagnostic and prognostic biomarker for risk stratification in the emergency department BMC Med 10 2012 7
4. S.Q. Khan, O.S. Dhillon, and R.J. O'Brien C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) study Circulation 115 2007 2103 2110
5. T. Reichlin, W. Hochholzer, and C. Stelzig Incremental value of copeptin for rapid rule out of acute myocardial infarction J Am Coll Cardiol 54 2009 60 68
6. T. Keller, S. Tzikas, and T. Zeller Copeptin improves early diagnosis of acute myocardial infarction J Am Coll Cardiol 55 2010 2096 2106
7. F.E. Harrell Regression Modeling Strategies With Applications to Linear Models, Logistic Regression, and Survival Analysis 2001 Springer
8. P.J. Heagerty, T. Lumley, and M.S. Pepe Time-dependent ROC curves for censored survival data and a diagnostic markers Biometrics 56 2000 337 344
9. K. Thygesen, J. Mair, and H. Katus Recommendations for the use of cardiac troponin measurement in acute cardiac care Eur Heart J 31 2010 2197 2206
10. Y.L. Gu, A.A. Voors, and F. Zijlstra Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction Clin Res Cardiol 100 2011 1069 1076
11. E. Giannitsis, T. Kehayova, M. Vafaie, and H.A. Katus Combined testing of high-sensitivity troponin T and copeptin on presentation at prespecified cutoffs improves rapid rule-out of non-ST-segment elevation myocardial infarction Clin Chem 57 2011 1452 1455
12. H.M. McAlpine, J.J. Morton, B. Leckie, A. Rumley, G. Gillen, and H.J. Dargie Neuroendocrine activation after acute myocardial infarction Br Heart J 60 1988 117 124
13. R.A. Donald, I.G. Crozier, and S.G. Foy Plasma corticotrophin releasing hormone, vasopressin, ACTH and cortisol responses to acute myocardial infarction Clin Endocrinol (Oxf) 40 1994 499 504
14. C.J. Charles, S.J. Rogers, R.A. Donald, H. Ikram, T. Prickett, and A.M. Richards Hypothalamo-pituitary-adrenal axis response to coronary artery embolization: an ovine model of acute myocardial infarction J Endocrinol 152 1997 489 493
15. M. Katan, N. Morgenthaler, and I. Widmer Copeptin, a stable peptide derived from the vasopressin precursor, correlates with the individual stress level Neuro Endocrinol Lett 29 2008 341 346
16. A.A. Voors, S. von Haehling, and S.D. Anker C-terminal provasopressin (copeptin) is a strong prognostic marker in patients with heart failure after an acute myocardial infarction: results from the OPTIMAAL study Eur Heart J 30 2009 1187 1194
17. D. Kelly, I.B. Squire, and S.Q. Khan C-terminal provasopressin (copeptin) is associated with left ventricular dysfunction, remodeling, and clinical heart failure in survivors of myocardial infarction J Card Fail 14 2008 739 745
18. M.A. Konstam, M. Gheorghiade, and J.C. Burnett Jr. Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial JAMA 297 2007 1319 1331
19. M. Gheorghiade, M.A. Konstam, and J.C. Burnett Jr. Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials JAMA 297 2007 1332 1343
20. K. Wada, A. Fujimori, and U. Matsukawa Intravenous administration of conivaptan hydrochloride improves cardiac hemodynamics in rats with myocardial infarction-induced congestive heart failure Eur J Pharmacol 507 2005 145 151
21. I. Tentzeris, R. Jarai, and S. Farhan Complementary role of copeptin and high-sensitivity troponin in predicting outcome in patients with stable chronic heart failure Eur J Heart Fail 13 2011 726 733
22. U. Alehagen, U. Dahlstrom, J.F. Rehfeld, and J.P. Goetze Association of copeptin and N-terminal proBNP concentrations with risk of cardiovascular death in older patients with symptoms of heart failure JAMA 305 2011 2088 2095
23. S. Neuhold, M. Huelsmann, and G. Strunk Comparison of copeptin, B-type natriuretic peptide, and amino-terminal pro-B-type natriuretic peptide in patients with chronic heart failure: prediction of death at different stages of the disease J Am Coll Cardiol 52 2008 266 272
24. W.F. Peacock, R. Nowak, and R. Christenson Short-term mortality risk in emergency department acute heart failure Acad Emerg Med 18 2011 947 958
25. A. Maisel, Y. Xue, and K. Shah Increased 90-day mortality in patients with acute heart failure with elevated copeptin: secondary results from the Biomarkers in Acute Heart Failure (BACH) study Circulation Heart Fail 4 2011 613 620