Additional diagnostic and prognostic value of copeptin ultra-sensitive for diagnosis of non-ST-elevation myocardial infarction in older patients presenting to the emergency department

Clinical Chemistry and Laboratory Medicine

Volumn 51, Issue 6, 2013, Pages 1307-1319

  Bahrmann, Philipp ^a   Bahrmann, Anke ^a   Breithardt, Ole A ^a   Daniel, Werner G ^a   Christ, Michael ^b   Sieber, Cornel C ^a   Bertsch, Thomas ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b Nuremberg Hospital   (Germany)

Author keywords

Aged; Copeptins; Emergencies; Myocardial infarction; Troponin

Indexed keywords

COPEPTIN;

AGED; ARTICLE; BARTHEL INDEX; CARDIOVASCULAR MORTALITY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; FOLLOW UP; GERIATRIC PATIENT; HEART FAILURE; HEART MUSCLE NECROSIS; HUMAN; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; RECEIVER OPERATING CHARACTERISTIC; REFERENCE VALUE; SYSTOLIC BLOOD PRESSURE; THORAX PAIN; UNSTABLE ANGINA PECTORIS;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; EMERGENCY SERVICE, HOSPITAL; GLYCOPEPTIDES; HUMANS; MYOCARDIAL INFARCTION; PROGNOSIS; PROSPECTIVE STUDIES; TROPONIN I; TROPONIN T;

EID: 84882303038     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2012-0401     Document Type: Article

References (33)

1. Mehta RH, Rathore SS, Radford MJ, Wang Y, Wang Y, Krumholz HM. Acute myocardial infarction in the elderly: differences by age. J Am Coll Cardiol 2001;38:736-41.
2. Soiza RL, Leslie SJ, Harrild K, Peden NR, Hargreaves AD. Age-dependent differences in presentation, risk factor profile, and outcome of suspected acute coronary syndrome. J Am Geriatr Soc 2005;53:1961-5.
3. Schoenenberger AW, Radovanovic D, Stauffer J-C, Windecker S, Urban P, Eberli FR, et al. Age-related differences in the use of guideline-recommended medical and interventional therapies for acute coronary syndromes: a cohort study. J Am Geriatr Soc 2008;56:510-6.
4. Hamm CW, Bassand J-P, Agewall S, Bax J, Boersma E, Bueno H, et al. ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2011;32:2999-3054.
5. Reiter M, Twerenbold R, Reichlin T, Haaf P, Peter F, Meissner J, et al. Early diagnosis of acute myocardial infarction in the elderly using more sensitive cardiac troponin assays. Eur Heart J 2011;32:1379-89.
6. Christ M, Bertsch T, Popp S, Bahrmann P, Heppner HJ, Müller C. High-sensitivity troponin assays in the evaluation of patients with acute chest pain in the emergency department. Clin Chem Lab Med 2011;49:1955-63.
7. Reichlin T, Hochholzer W, Stelzig C, Laule K, Freidank H, Morgenthaler N, et al. Incremental value of copeptin for rapid rule out of acute myocardial infarction. J Am Coll Cardiol 2009;54:60-8.
8. Keller T, Tzikas S, Zeller T, Czyz E, Lillpopp L, Ojeda FM, et al. Copeptin improves early diagnosis of acute myocardial infarction. J Am Coll Cardiol 2010;55:2096-106.
9. Lippi G, Plebani M, Di Somma S, Monzani V, Tubaro M, Volpe M, et al. Considerations for early acute myocardial infarction rule-out for emergency department chest pain patients: the case of copeptin. Clin Chem Lab Med 2012;50:243-53.
10. Morgenthaler NG, Struck J, Alonso C, Bergmann A. Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin. Clin Chem 2006;52:112-9.
11. Von Haehling S, Stojakovic T, Bigalke B. Copeptin-a novel marker in acute myocardial infarction. Clin Chem 2012;58:307-9.
12. Stoiser B, Mörtl D, Hülsmann M, Berger R, Struck J, Morgenthaler NG, et al. Copeptin, a fragment of the vasopressin precursor, as a novel predictor of outcome in heart failure. Eur J Clin Invest 2006;36:771-8.
13. Gegenhuber A, Struck J, Dieplinger B, Poelz W, Pacher R, Morgenthaler NG, et al. Comparative evaluation of B-type natriuretic peptide, mid-regional pro-A-type natriuretic peptide, mid-regional pro-adrenomedullin, and copeptin to predict 1-year mortality in patients with acute destabilized heart failure. J Card Fail 2007;13:42-9.
14. Khan S, Dhillon O, O'Brien R, Struck J, Quinn P, Morgenthaler N, et al. C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) study. Circulation 2007;115:2103-10.
15. Maisel A, Xue Y, Shah K, Mueller C, Nowak R, Peacock WF, et al. Increased 90-day mortality in patients with acute heart failure with elevated copeptin/clinical perspective. Circ Heart Fail 2011;4:613-20.
16. Potocki M, Reichlin T, Thalmann S, Zellweger C, Twerenbold R, Reiter M, et al. Diagnostic and prognostic impact of copeptin and high-sensitivity cardiac troponin T in patients with pre-existing coronary artery disease and suspected acute myocardial infarction. Heart 2012;98:558-65.
17. Mahoney F, Barthel D. Functional evaluation: the Barthel index. Md State Med J 1965;14:61-5.
18. Charlson M, Pompei P, Ales K, MacKenzie C. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373-83.
19. Fox KA, Dabbous OH, Goldberg RJ, Pieper KS, Eagle KA, Werf FV, et al. Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE). Br Med J 2006;333:1091.
20. Hauer K, Lamb SE, Jorstad EC, Todd C, Becker C. Systematic review of definitions and methods of measuring falls in randomised controlled fall prevention trials. Age Ageing 2006;35:5-10.
21. Christ M, Popp S, Pohlmann H, Poravas M, Umarov D, Bach R, et al. Implementation of high sensitivity cardiac troponin T measurement in the emergency department. Am J Med 2010;123:1134-42.
22. Thygesen K, Alpert JS, White HD, Jaffe AS, Apple FS, Galvani M, et al. Universal definition of myocardial infarction. Eur Heart J 2007;28:2525-38.
23. NACB Writing Group, Wu AH, Jaffe AS, Apple FS, Jesse RL, Francis GL, et al. National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: use of cardiac troponin and B-type natriuretic peptide or N-terminal proB-type natriuretic peptide for etiologies other than acute coronary syndromes and heart failure. Clin Chem 2007;53:2086-96.
24. Saenger A, Beyrau R, Braun S, Cooray R, Dolci A, Freidank H, et al. Multicenter analytical evaluation of a high-sensitivity troponin T assay. Clin Chim Acta 2011;412:748-54.
25. Pencina MJ, Steyerberg EW, D'Agostino Sr. RB. Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers. Stat Med 2011;30:11-21.
26. Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, et al. Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. J Fam Pract 2004;21:4-10.
27. Giannitsis E, Kehayova T, Mehrshad V, Katus H. Combined testing of high-sensitivity troponin T and copeptin on presentation at prespecified cutoffs improves rapid rule-out of non-ST-segment elevation myocardial infarction. Clin Chem 2011;57:1452-5.
28. Charpentier S, Maupas-Schwalm F, Cournot M, Elbaz M, Botella JM, Lauque D. Combination of copeptin and troponin assays to rapidly rule out non-ST elevation myocardial infarction in the emergency department. Acad Emerg Med 2012;19:517-24.
29. Gu Y, Voors A, Zijlstra F, Hillege H, Struck J, Masson S, et al. Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction. Clin Res Cardiol 2011;100:1069-76.
30. Morgenthaler NG, Struck J, Jochberger S, Dünser MW. Copeptin: clinical use of a new biomarker. Trends Endocrinol Metab 2008;19:43-9.
31. Karakas M, Januzzi JL, Meyer J, Lee H, Schlett CL, Truong QA, et al. Copeptin does not add diagnostic information to high-sensitivity troponin T in low-to intermediate-risk patients with acute chest pain: results from the Rule Out Myocardial Infarction by Computed Tomography (ROMICAT) Study. Clin Chem 2011;57:1137-45.
32. Khan S, Dhillon O, Struck J, Quinn P, Morgenthaler N, Squire I, et al. C-terminal pro-endothelin-1 offers additional prognostic information in patients after acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) Study. Am Heart J 2007;154:736-42.
33. Rosengren A, Wallentin L, Simoons M, Gitt AK, Behar S, Battler A, et al. Age, clinical presentation, and outcome of acute coronary syndromes in the Euroheart acute coronary syndrome survey. Eur Heart J 2006;27:789-95.