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Volumn 17, Issue 19, 2015, Pages 4746-4749

Enantioselective Synthesis of syn-α-Aryl-β-hydroxy Weinreb Amides: Catalytic Asymmetric Roskamp Reaction of α-Aryl Diazo Weinreb Amides

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EID: 84942865568     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/acs.orglett.5b02268     Document Type: Article
Times cited : (27)

References (38)
  • 2
    • 0034635481 scopus 로고    scopus 로고
    • Arya, P.; Qin, H. Tetrahedron 2000, 56, 917 10.1016/S0040-4020(99)00964-3
    • (2000) Tetrahedron , vol.56 , pp. 917
    • Arya, P.1    Qin, H.2
  • 24
    • 72249098560 scopus 로고    scopus 로고
    • Asymmetric Roskamp reaction between piperidine α-phenyl diazoamide and p-tolualdehyde provided 1,2-hydride shift product 1 as a major product in 50% yield with a 1 / 3 ratio of 6/1. For the diastereocontrol effect of diazoamide, see
    • Asymmetric Roskamp reaction between piperidine α-phenyl diazoamide and p-tolualdehyde provided 1,2-hydride shift product 1 as a major product in 50% yield with a 1 / 3 ratio of 6/1. For the diastereocontrol effect of diazoamide, see: Marcoux, D.; Goudreau, S. R.; Charette, A. B. J. Org. Chem. 2009, 74, 8939 10.1021/jo902066y
    • (2009) J. Org. Chem. , vol.74 , pp. 8939
    • Marcoux, D.1    Goudreau, S.R.2    Charette, A.B.3
  • 26
    • 84942920790 scopus 로고    scopus 로고
    • Aryl diazo-Weinreb amides were prepared from arylacetyl chloride in two steps. (See the Supporting Information.)
    • α-Aryl diazo-Weinreb amides were prepared from arylacetyl chloride in two steps. (See the Supporting Information.)


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