메뉴 건너뛰기




Volumn 10, Issue 8, 2015, Pages

The accumulation of VEGFA in the glomerular basement membrane and its relationship with podocyte injury and proteinuria in alport syndrome

Author keywords

[No Author keywords available]

Indexed keywords

NEPHRIN; SYNAPTOPODIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2; ACTIN BINDING PROTEIN; BIOLOGICAL MARKER; KDR PROTEIN, HUMAN; MEMBRANE PROTEIN; SYNPO PROTEIN, HUMAN; VEGFA PROTEIN, HUMAN;

EID: 84942860248     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0135648     Document Type: Article
Times cited : (15)

References (29)
  • 1
    • 67449106523 scopus 로고    scopus 로고
    • The renal lesions of Alport syndrome
    • PMID: 19470679
    • Heidet L, Gubler MC. The renal lesions of Alport syndrome. J Am Soc Nephrol, 2009; 20: 1210-1215. doi: 10.1681/ASN.2008090984 PMID: 19470679
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1210-1215
    • Heidet, L.1    Gubler, M.C.2
  • 2
    • 84863984599 scopus 로고    scopus 로고
    • The role of molecular genetics in diagnosing familial hematuria(s)
    • PMID: 21688191
    • Deltas C, Pierides A, Voskarides K. The role of molecular genetics in diagnosing familial hematuria(s). Pediatr Nephrol, 2012; 27: 1221-1231. doi: 10.1007/s00467-011-1935-5 PMID: 21688191
    • (2012) Pediatr Nephrol , vol.27 , pp. 1221-1231
    • Deltas, C.1    Pierides, A.2    Voskarides, K.3
  • 3
    • 78649829302 scopus 로고    scopus 로고
    • Imaging of the porous ultrastructure of the glomerular epithelial filtration slit
    • PMID: 21030599
    • Gagliardini E, Conti S, Benigni A, Remuzzi G, Remuzzi A. Imaging of the porous ultrastructure of the glomerular epithelial filtration slit. J Am Soc Nephrol, 2010; 21: 2081-2089. doi: 10.1681/ASN 010020199 PMID: 21030599
    • (2010) J Am Soc Nephrol , vol.21 , pp. 2081-2089
    • Gagliardini, E.1    Conti, S.2    Benigni, A.3    Remuzzi, G.4    Remuzzi, A.5
  • 4
    • 77955870854 scopus 로고    scopus 로고
    • Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease
    • PMID: 20375978
    • Veron D, Reidy KJ, Bertuccio C, Teichman J, Villegas G, Jimenez J, et al. Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease. Kidney Int, 2010; 77: 989-999. doi: 10.1038/ki 010.64 PMID: 20375978
    • (2010) Kidney Int , vol.77 , pp. 989-999
    • Veron, D.1    Reidy, K.J.2    Bertuccio, C.3    Teichman, J.4    Villegas, G.5    Jimenez, J.6
  • 5
    • 0036140206 scopus 로고    scopus 로고
    • Downregulation of vascular endothelial growth factor and its receptors in the kidney in rats with puromycin aminonucleoside nephrosis
    • PMID: 11744811
    • Fan L, Wakayama T, Yokoyama S, Amano O, Iseki S. Downregulation of vascular endothelial growth factor and its receptors in the kidney in rats with puromycin aminonucleoside nephrosis. Nephron, 2002; 90: 95-102. PMID: 11744811
    • (2002) Nephron , vol.90 , pp. 95-102
    • Fan, L.1    Wakayama, T.2    Yokoyama, S.3    Amano, O.4    Iseki, S.5
  • 7
    • 81155123707 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes
    • PMID: 21937443
    • Bertuccio C, Veron D, Aggarwal PK, Holzman L, Tufro A. Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes. J Biol Chem, 2011; 286: 39933-39944. doi: 10.1074/jbc.M111.241620 PMID: 21937443
    • (2011) J Biol Chem , vol.286 , pp. 39933-39944
    • Bertuccio, C.1    Veron, D.2    Aggarwal, P.K.3    Holzman, L.4    Tufro, A.5
  • 8
    • 33646401549 scopus 로고    scopus 로고
    • Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
    • PMID: 16543952
    • Verma R, Kovari I, Soofi A, Nihalani D, Patrie K, Holzman LB. Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest, 2006; 116: 1346-1359. PMID: 16543952
    • (2006) J Clin Invest , vol.116 , pp. 1346-1359
    • Verma, R.1    Kovari, I.2    Soofi, A.3    Nihalani, D.4    Patrie, K.5    Holzman, L.B.6
  • 9
    • 33845953426 scopus 로고    scopus 로고
    • Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF
    • PMID: 16966330
    • Lamalice L, Houle F, Huot J. Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF. J Biol Chem, 2006; 281: 34009-34020. PMID: 16966330
    • (2006) J Biol Chem , vol.281 , pp. 34009-34020
    • Lamalice, L.1    Houle, F.2    Huot, J.3
  • 10
    • 0030996743 scopus 로고    scopus 로고
    • Alport's syndrome
    • PMID: 9138159
    • Flinter F. Alport's syndrome. J Med Genet, 1997; 34: 326-330. PMID: 9138159
    • (1997) J Med Genet , vol.34 , pp. 326-330
    • Flinter, F.1
  • 12
    • 79954672191 scopus 로고    scopus 로고
    • Microencapsulation of inorganic nanocrystals into PLGA microsphere vaccines enables their intracellular localization in dendritic cells by electron and fluorescence microscopy
    • PMID: 21223984
    • Schliehe C, Schliehe C, Thiry M, Tromsdorf UI, Hentschel J, Weller H, et al. Microencapsulation of inorganic nanocrystals into PLGA microsphere vaccines enables their intracellular localization in dendritic cells by electron and fluorescence microscopy. J Control Release, 2011; 151: 278-285. doi: 10.1016/j. jconrel.2011.01.005 PMID: 21223984
    • (2011) J Control Release , vol.151 , pp. 278-285
    • Schliehe, C.1    Schliehe, C.2    Thiry, M.3    Tromsdorf, U.I.4    Hentschel, J.5    Weller, H.6
  • 13
  • 14
    • 0034073758 scopus 로고    scopus 로고
    • X-linked Alport syndrome: Natural history in 195 families and genotype-phenotype correlations in males
    • PMID: 10752524
    • Jais JP, Knebelmann B, Giatras I, De Marchi M, Rizzoni G, Renieri A, et al. X-linked Alport syndrome: natural history in 195 families and genotype-phenotype correlations in males. J Am Soc Nephrol, 2000; 11: 649-657. PMID: 10752524
    • (2000) J Am Soc Nephrol , vol.11 , pp. 649-657
    • Jais, J.P.1    Knebelmann, B.2    Giatras, I.3    De Marchi, M.4    Rizzoni, G.5    Renieri, A.6
  • 15
    • 34250374471 scopus 로고    scopus 로고
    • Role of the VEGF-A signaling pathway in the glomerulus: Evidence for crosstalk between components of the glomerular filtration barrier
    • PMID: 17570946
    • Eremina V, Baelde HJ, Quaggin SE. Role of the VEGF-a signaling pathway in the glomerulus: evidence for crosstalk between components of the glomerular filtration barrier. Nephron Physiol, 2007; 106: p32-p37. PMID: 17570946
    • (2007) Nephron Physiol , vol.106 , pp. p32-p37
    • Eremina, V.1    Baelde, H.J.2    Quaggin, S.E.3
  • 16
    • 0028950364 scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney
    • PMID: 7864162
    • Simon M, Grone HJ, Johren O, Kullmer J, Plate KH, Risau W, et al. Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney. Am J Physiol, 1995; 268: F240-F250. PMID: 7864162
    • (1995) Am J Physiol , vol.268 , pp. F240-F250
    • Simon, M.1    Grone, H.J.2    Johren, O.3    Kullmer, J.4    Plate, K.H.5    Risau, W.6
  • 17
    • 31144440464 scopus 로고    scopus 로고
    • Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa
    • PMID: 16291795
    • Gao X, Chen X, Taglienti M, Rumballe B, Little MH, Kreidberg JA. Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa. Development, 2005; 132: 5437-5449. PMID: 16291795
    • (2005) Development , vol.132 , pp. 5437-5449
    • Gao, X.1    Chen, X.2    Taglienti, M.3    Rumballe, B.4    Little, M.H.5    Kreidberg, J.A.6
  • 18
    • 0037370325 scopus 로고    scopus 로고
    • Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
    • PMID: 12618525
    • Eremina V, Sood M, Haigh J, Nagy A, Lajoie G, Ferrara N, et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest, 2003; 111: 707-716. PMID: 12618525
    • (2003) J Clin Invest , vol.111 , pp. 707-716
    • Eremina, V.1    Sood, M.2    Haigh, J.3    Nagy, A.4    Lajoie, G.5    Ferrara, N.6
  • 19
    • 77957225604 scopus 로고    scopus 로고
    • Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans
    • PMID: 20395257
    • Hohenstein B, Colin M, Foellmer C, Amann KU, Brekken RA, Daniel C, et al. Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans. Nephrol Dial Transplant, 2010; 25: 3170-3180. doi: 10.1093/ndt/gfq200 PMID: 20395257
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3170-3180
    • Hohenstein, B.1    Colin, M.2    Foellmer, C.3    Amann, K.U.4    Brekken, R.A.5    Daniel, C.6
  • 20
    • 79960139810 scopus 로고    scopus 로고
    • WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier
    • PMID: 21719793
    • Schumacher VA, Schlotzer-Schrehardt U, Karumanchi SA, Shi X, Zaia J, Jeruschke S, et al. WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier. J Am Soc Nephrol, 2011; 22: 1286-1296. doi: 10.1681/ASN.2010080860 PMID: 21719793
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1286-1296
    • Schumacher, V.A.1    Schlotzer-Schrehardt, U.2    Karumanchi, S.A.3    Shi, X.4    Zaia, J.5    Jeruschke, S.6
  • 21
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • PMID: 12778165
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med, 2003; 9: 669-676. PMID: 12778165
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 22
    • 33746610964 scopus 로고    scopus 로고
    • Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP
    • PMID: 16597608
    • Guan F, Villegas G, Teichman J, Mundel P, Tufro A. Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP. Am J Physiol Renal Physiol, 2006; 291: F422-F428. PMID: 16597608
    • (2006) Am J Physiol Renal Physiol , vol.291 , pp. F422-F428
    • Guan, F.1    Villegas, G.2    Teichman, J.3    Mundel, P.4    Tufro, A.5
  • 23
    • 77957225604 scopus 로고    scopus 로고
    • Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans
    • PMID: 20395257
    • Hohenstein B, Colin M, Foellmer C, Amann KU, Brekken RA, Daniel C, et al. Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans. Nephrol Dial Transplant, 2010; 25: 3170-3180. doi: 10.1093/ndt/gfq200 PMID: 20395257
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3170-3180
    • Hohenstein, B.1    Colin, M.2    Foellmer, C.3    Amann, K.U.4    Brekken, R.A.5    Daniel, C.6
  • 24
    • 77957861954 scopus 로고    scopus 로고
    • Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling
    • PMID: 20688931
    • Sison K, Eremina V, Baelde H, Min W, Hirashima M, Fantus IG, et al. Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling. J Am Soc Nephrol, 2010; 21: 1691-1701. doi: 10.1681/ASN.2010030295 PMID: 20688931
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1691-1701
    • Sison, K.1    Eremina, V.2    Baelde, H.3    Min, W.4    Hirashima, M.5    Fantus, I.G.6
  • 25
    • 67649778673 scopus 로고    scopus 로고
    • Phosphorylation of nephrin triggers ca2+ signaling by recruitment and activation of phospholipase c-{gamma} 1
    • PMID: 19179337
    • Harita Y, Kurihara H, Kosako H, Tezuka T, Sekine T, Igarashi T, et al. Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1. J Biol Chem, 2009; 284: 8951-8962. doi: 10.1074/jbc.M806851200 PMID: 19179337
    • (2009) J Biol Chem , Issue.284 , pp. 8951-8962
    • Harita, Y.1    Kurihara, H.2    Kosako, H.3    Tezuka, T.4    Sekine, T.5    Igarashi, T.6
  • 26
    • 84942869791 scopus 로고    scopus 로고
    • Relationship between ultrastructural lesions of glomerular filtration barrier and proteinuria in Alport syndrome
    • Wang HY, Sun LZ, Wu JL, Jiang XY, Mo Y, Tong HJ. Relationship between ultrastructural lesions of glomerular filtration barrier and proteinuria in Alport syndrome. Zhongguo bing li sheng li za zhi, 2013; 29: 361-363.
    • (2013) Zhongguo Bing Li Sheng Li Za Zhi , vol.29 , pp. 361-363
    • Wang, H.Y.1    Sun, L.Z.2    Wu, J.L.3    Jiang, X.Y.4    Mo, Y.5    Tong, H.J.6
  • 27
    • 34548324281 scopus 로고    scopus 로고
    • Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes
    • PMID: 17569780
    • Yanagida-Asanuma E, Asanuma K, Kim K, Donnelly M, Young CH, Hyung CJ, et al. Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes. Am J Pathol, 2007; 171: 415-427. PMID: 17569780
    • (2007) Am J Pathol , vol.171 , pp. 415-427
    • Yanagida-Asanuma, E.1    Asanuma, K.2    Kim, K.3    Donnelly, M.4    Young, C.H.5    Hyung, C.J.6
  • 28
    • 78149298673 scopus 로고    scopus 로고
    • Induction of podocyte VEGF164 overexpression at different stages of development causes congenital nephrosis or steroid-resistant nephrotic syndrome
    • PMID: 20829436
    • Veron D, Reidy K, Marlier A, Bertuccio C, Villegas G, Jimenez J, et al. Induction of podocyte VEGF164 overexpression at different stages of development causes congenital nephrosis or steroid-resistant nephrotic syndrome. Am J Pathol, 2010; 177: 2225-2233. PMID: 20829436
    • (2010) Am J Pathol , vol.177 , pp. 2225-2233
    • Veron, D.1    Reidy, K.2    Marlier, A.3    Bertuccio, C.4    Villegas, G.5    Jimenez, J.6
  • 29
    • 33845953426 scopus 로고    scopus 로고
    • Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF
    • PMID: 16966330
    • Lamalice L, Houle F, Huot J. Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF. J Biol Chem, 2006; 281: 34009-34020. PMID: 16966330
    • (2006) J Biol Chem , vol.281 , pp. 34009-34020
    • Lamalice, L.1    Houle, F.2    Huot, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.