Cell Adhesion Minimization by a Novel Mesh Culture Method Mechanically Directs Trophoblast Differentiation and Self-Assembly Organization of Human Pluripotent Stem Cells

Tissue Engineering - Part C: Methods

Volumn 21, Issue 10, 2015, Pages 1105-1115

  Okeyo, Kennedy Omondi ^a   Kurosawa, Osamu ^a   Yamazaki, Satoshi ^a   Oana, Hidehiro ^a   Kotera, Hidetoshi ^b   Nakauchi, Hiromitsu ^a   Washizu, Masao ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION; CELLS; MESH GENERATION; SELF ASSEMBLY; STEM CELLS;

CELL ATTACHMENTS; CELL-SUBSTRATE ADHESION; CULTURE METHODS; DRUG DEVELOPMENT; HUMAN CHORIONIC GONADOTROPINS; LINEAGE SPECIFICATION; MECHANICAL METHODS; PLURIPOTENT STEM CELLS;

CYTOLOGY;

CHORIONIC GONADOTROPIN; TRANSCRIPTION FACTOR CDX2;

ARTICLE; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL LINEAGE; CELL PROLIFERATION; CELL STIMULATION; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; CULTURE MEDIUM; CYST; HUMAN; HUMAN CELL; MICROTECHNOLOGY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TROPHOBLAST; CELL CULTURE TECHNIQUE; CYTOLOGY; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PROCEDURES;

CELL ADHESION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; TROPHOBLASTS;

EID: 84942846410     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2015.0038     Document Type: Article

References (45)

1. Keller, G. Embryonic stem cell differentiation: emergence of a newera in biology andmedicine. GenesDev 19, 1129, 2005.
2. Jiang, Z. , Han, Y. , and Cao, X. Induced pluripotent stem cell (iPSCs) and their application in immunotherapy. Cell Mol Immunol 11, 17, 2014.
3. Chen, Y. , Wang, K. , Gong, Y. G. , Khoo, S. K. , and Leach, R. Roles of CDX2 and EOMES in human induced trophoblast progenitor cells. Biochem Biophys Res Commun 431, 197, 2013.
4. Amita, M. , Adachi, K. , Alexenko, A. P. , Sinha, S. , Schust, D. J. , Schulz, L. C. , Roberts, R. M. , and Ezashi, T. Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4. Proc Natl Acad Sci U S A 110, E1212, 2013.
5. Tamm, C. , Pijuan Galito, S. , and Anneren, C. A comparative study of protocols for mouse embryonic stem cell culturing. PLoS One 8, e81156, 2013.
6. Xu, R. , Chen, X. , Li, D. , Li, R. , Addicks, G. , Glennon, C. , Zwaka, T. , and Thomson, J. BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol 284, 143 2002.
7. Bernardo, A. S. , Faial, T. , Gardner, L. , Niakan, K. K. , Ortmann, D. , Senner, C. E. , Callery, E. M. , Trotter, M. W. , Hemberger, M. , Smith, J. C. , Bardwell, L. , Moffett, A. , and Pedersen, R. A. BRACHYURY and CDX2 mediate BMPinduced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. Cell Stem Cell 9, 144, 2011.
8. Schulz, L. C. , Ezashi, T. , Das, P. , Westfall, S. D. , Livingston, K. A. , and Roberts, R. M. Human embryonic stem cells as models for trophoblast differentiation. Placenta 29 Supplement, 10, 2008.
9. Chen, D. , Zhao, M. , and Mundy, G. R. Bone morphogenetic proteins. Growth Factors 22, 233, 2004.
10. Chen, Y. , Wang, K. , Chandramouli, G. V. , Knott, J. G. , and Leach, R. Trophoblast lineage cells derived from human induced pluripotent stem cells. Biochem Biophys Res Commun 436, 677, 2013.
11. Doi, A. , Park, I. H. , Wen, B. , Murakami, P. , Aryee, M. J. , Irizarry, R. , Herb, B. , Ladd-Acosta, C. , Rho, J. , Loewer, S. , Miller, J. , Schlaeger, T. , Daley, G. Q. , and Feinberg, A. P. Differential methylation of tissue-and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. NatGenet 41, 1350, 2009.
12. Kim, K. , Doi, A. , Wen, B. , Ng, K. , Zhao, R. , Cahan, P. , Kim, J. , Aryee, M. J. , Ji, H. , Ehrlich, L. I. , Yabuuchi, A. , Takeuchi, A. , Cunniff, K. C. , Hongguang, H. , McKinney-Freeman, S. , Naveiras, O. , Yoon, T. J. , Irizarry, R. A. , Jung, N. , Seita, J. , Hanna, J. , Murakami, P. , Jaenisch, R. , Weissleder, R. , Orkin, S. H. , Weissman, I. L. , Feinberg, A. P. , and Daley, G. Q. Epigenetic memory in induced pluripotent stem cells. Nature 467, 285, 2010.
13. Dalby, M. J. , Gadegaard, N. , and Oreffo, R. O. Harnessing nanotopography and integrin-matrix interactions to influence stem cell fate. Nat Mater 13, 558, 2014.
14. Nelson, C. M. , and Bissell, M. J. Of extracellular matrix, scaffolds, and signaling: Tissue architecture regulates development, homeostasis, and cancer. Annu Rev Cell Dev Biol 22, 287, 2006.
15. Scadden, D. T. The stem-cell niche as an entity of action. Nature 441, 1075, 2006.
16. Engler, A. J. , Sen, S. , Sweeney, H. L. , and Discher, D. E. Matrix elasticity directs stem cell lineage specification. Cell 126, 677, 2006.
17. Li, Z. , Gong, Y. , Sun, S. , Du, Y. , Lu, D. , Liu, X. , and Long, M. Differential regulation of stiffness, topography, and dimension of substrates in rat mesenchymal stem cells. Biomaterials 34, 7616, 2013.
18. Kingham, E. , White, K. , Gadegaard, N. , Dalby, M. J. , and Oreffo, R. O. Nanotopographical cues augment mesenchymal differentiation of human embryonic stem cells. Small 9, 2140, 2013.
19. Hogeweg, P. Evolving mechanisms of morphogenesis: on the interplay between differential adhesion and cell differentiation. J Theor Biol 203, 317, 2000.
20. Kilian, K. A. , Bugarija, B. , Lahn, B. T. , and Mrksich, M. Geometric cues for directing the differentiation of mesenchymal stemcells. ProcNatlAcad Sci U S A 107, 4872, 2010.
21. Chen, G. , Gulbranson, D. R. , Hou, Z. , Bolin, J. M. , Ruotti, V. , Probasco, M. D. , Smuga-Otto, K. , Howden, S. E. , Diol, N. R. , Propson, N. E. , Wagner, R. , Lee, G. O. , Antosiewicz-Bourget, J. , Teng, J. M. C. , and Thomson, J. A. Chemically defined conditions for human iPSC derivation and culture. Nat Methods 8, 424, 2011.
22. Coucouvanis, E. , and Martin, G. R. Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo. Cell 83, 279, 1995.
23. Abad, M. , Mosteiro, L. , Pantoja, C. , Canamero, M. , Rayon, T. , Ors, I. , Grana, O. , Megias, D. , Dominguez, O. , Martinez, D. , Manzanares, M. , Ortega, S. , and Serrano, M. Reprogramming in vivo produces teratomas and iPS cells with totipotency features. Nature 502, 340, 2013.
24. Risau, W. , Sariola, H. , Zerwes, H. G. , Sasse, J. , Ekblom, P. , Kemler, R. , and Doetschman, T. Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development 102, 471, 1988.
25. Huang, X. , Han, X. , Uyunbilig, B. , Zhang, M. , Duo, S. , Zuo, Y. , Zhao, Y. , Yun, T. , Tai, D. , Wang, C. , Li, J. , Li, X. , and Li, R. Establishment of bovine trophoblast stem-like cells from in vitro-produced blastocyst-stage embryos using two inhibitors. Stem Cells Dev 23, 1501, 2014.
26. Oda, M. , Tanaka, S. , Yamazaki, Y. , Ohta, H. , Iwatani, M. , Suzuki, M. , Ohgane, J. , Hattori, N. , Yanagimachi, R. , Wakayama, T. , and Shiota, K. Establishment of trophoblast stem cell lines from somatic cell nuclear-transferred embryos. Proc Natl Acad Sci U S A 106, 16293, 2009.
27. Bodnar, A. G. , Ouellette, M. , Frolkis, M. , Holt, S. E. , Chiu, C. P. , Morin, G. B. , Harley, C. B. , Shay, J. W. , Lichtsteiner, S. , and Wright, W. E. Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349, 1998.
28. Coutifaris, C. , Kao, L. C. , Sehdev, H. M. , Chin, U. , Babalola, G. O. , Blaschuk, O. W. , and Strauss, J. F. , 3rd. E-cadherin expression during the differentiation of human trophoblasts. Development 113, 767, 1991.
29. De Los Angeles, A. , and Daley, G. Q. Stem cells: reprogramming in situ. Nature 502, 309, 2013.
30. Gerami-Naini, B. , Dovzhenko, O. V. , Durning, M. , Wegner, F. H. , Thomson, J. A. , and Golos, T. G. Trophoblast differentiation in embryoid bodies derived from human embryonic stem cells. Endocrinology 145, 1517, 2004.
31. Lu, D. , Luo, C. , Zhang, C. , Li, Z. , and Long, M. Differential regulation of morphology and stemness of mouse embryonic stem cells by substrate stiffness and topography. Biomaterials 35, 3945, 2014.
32. Roper, S. , and Hemberger, M. Defining pathways that enforce cell lineage specification in early development and stem cells. Cell Cycle 8, 1515, 2009.
33. Strumpf, D. , Mao, C. A. , Yamanaka, Y. , Ralston, A. , Chawengsaksophak, K. , Beck, F. , and Rossant, J. Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development 132, 2093, 2005.
34. Roberts, R. M. , and Fisher, S. J. Trophoblast stem cells. Biol Reprod 84, 412, 2011.
35. Schiffmacher, A. T. , and Keefer, C. L. CDX2 regulates multiple trophoblast genes in bovine trophectoderm CT-1 cells. Mol Reprod Dev 80, 826, 2013.
36. Niwa, H. , Toyooka, Y. , Shimosato, D. , Strumpf, D. , Takahashi, K. , Yagi, R. , and Rossant, J. Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell 123, 917, 2005.
37. Hemberger, M. Epigenetic landscape required for placental development. Cell Mol Life Sci 64, 2422, 2007.
38. Miyoshi, H. , and Adachi, T. Topography design concept of a tissue engineering scaffold for controlling cell function and fate through actin cytoskeletal modulation. Tissue Eng Part B Rev 20, 609, 2014.
39. Boettiger, D. Mechanical control of integrin-mediated adhesion and signaling. Curr Opin Cell Biol 24, 592, 2012.
40. Kanchanawong, P. , Shtengel, G. , Pasapera, A. M. , Ramko, E. B. , Davidson, M. W. , Hess, H. F. , and Waterman, C. M. Nanoscale architecture of integrin-based cell adhesions. Nature 468, 580, 2010.
41. Halbleib, J. M. , and Nelson, W. J. Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes Dev 20, 3199, 2006.
42. Larue, L. , Ohsugi, M. , Hirchenhain, J. , and Kemler, R. Ecadherin null mutant embryos fail to form a trophectoderm epithelium. Proc Natl Acad Sci U S A 91, 8263, 1994.
43. Steinberg, M. S. Reconstruction of tissues by dissociated cells. Some morphogenetic tissue movements and the sorting out of embryonic cells may have a common explanation. Science 141, 401, 1963.
44. Steinberg, M. S. , and Takeichi, M. Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc Natl Acad Sci U S A 91, 206, 1994.
45. Pieters, T. , and van Roy, F. Role of cell-cell adhesion complexes in embryonic stem cell biology. J Cell Sci 127, 2603, 2014.