Evaluation of circulating betatrophin levels in gestational diabetes mellitus

Gynecological Endocrinology

Volumn 31, Issue 8, 2015, Pages 652-656

  Erol, Onur ^a   Ellidaʇ, Hamit Yaşar ^b   Ayik, Hülya ^a   Özel, Mustafa Kemal ^a   Derbent, Aysel Uysal ^a   Yilmaz, Necat ^b  

^a MH Antalya Training and Research Hospital   (Turkey)

^b NONE   (Turkey)

Author keywords

Betatrophin; gestational diabetes mellitus; insulin resistance

Indexed keywords

BETATROPHIN; GLUCOSE; HEMOGLOBIN A1C; INSULIN; PROTEIN; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; LIPASIN PROTEIN, HUMAN; PEPTIDE HORMONE;

ADULT; ARTICLE; BODY MASS; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; GESTATIONAL AGE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN TREATMENT; MATERNAL AGE; ORAL GLUCOSE TOLERANCE TEST; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SYSTOLIC BLOOD PRESSURE; WEIGHT GAIN; BLOOD; DIET RESTRICTION; PHYSIOLOGY; PREGNANCY; YOUNG ADULT;

ADULT; BLOOD GLUCOSE; BODY MASS INDEX; CASE-CONTROL STUDIES; DIABETES, GESTATIONAL; FASTING; FEMALE; GESTATIONAL AGE; HUMANS; INSULIN; INSULIN RESISTANCE; PEPTIDE HORMONES; PREGNANCY; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84942835999     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513590.2015.1056142     Document Type: Article

References (21)

1. Perkins JM, Dunn JP, Jagasia SM. Perspectives in gestational diabetes mellitus: a review of screening, diagnosis, and treatment. Clin Diabetes 2007; 25: 57-62
2. Metzger BE, Lowe LP, Dyer AR, et al.; HAPO Study Cooperative Research Group. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med 2008; 358: 1991-2002
3. Catalano PM. Trying to understand gestational diabetes. Diabet Med 2014; 31: 273-81
4. Prentki M, Nolan CJ. Islet beta cell failure in type 2 diabetes. J Clin Invest 2006; 116: 1802-12
5. Ouaamari A, Kawamori D, Dirice E, et al. Liver-derived systemic factors drive beta cell hyperplasia in insulin-resistant states. Cell Rep 2013; 3: 401-10
6. Kulkarni RN, Mizrachi EB, Ocana AG, Stewart AF. Human β-cell proliferation and intracellular signaling: driving in the dark without a road map. Diabetes 2012; 61: 2205-13
7. Zhang R. Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels. Biochem Biophys Res Commun 2012; 424: 786-92
8. Wang Y, Quagliarini F, Gusarova V, et al. Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis. Proc Natl Acad Sci USA 2013; 110: 16109-14
9. Ren G, Kim JY, Smas CM. Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism. Am J Physiol Endocrinol Metab 2012; 303: 334-51
10. Yi P, Park JS, Melton DA. Betatrophin: a hormone that controls pancreatic β cell proliferation. Cell 2013; 153: 747-58
11. Metzger BE, Gabbe SG, Persson B, et al. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care 2010; 33: 676-82
12. Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-19
13. Gusarova V, Alexa CA, Na E, et al. ANGPTL8/betatrophin does not control pancreatic beta cell expansion. Cell 2014; 159: 691-6
14. Jiao Y, Le Lay J, Yu M, et al. Elevated mouse hepatic betatrophin expression does not increase human β-cell replication in the transplant setting. Diabetes 2014; 63: 1283-8
15. Espes D, Lau J, Carlsson PO. Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes. Diabetologia 2014; 57: 50-3
16. Fu Z, Berhane F, Fite A, et al. Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity. Sci Rep 2014; 23: 5013. doi: 10.1038/srep05013
17. Chen X, Lu P, He W, et al. Circulating betatrophin levels are increased in patients with type 2 diabetes and associated with insulin resistance. J Clin Endocrinol Metab 2015; 100: E96-100
18. Hu H, Sun W, Yu S, et al. Increased circulating levels of betatrophin in newly diagnosed type 2 diabetic patients. Diabetes Care 2014; 37: 2718-22
19. Gómez-Ambrosi J, Pascual E, Catalán V, et al. Circulating betatrophin concentrations are decreased in human obesity and type 2 diabetes. J Clin Endocrinol Metab 2014; 99: E2004-9
20. Fenzl A, Itariu BK, Kosi L, et al. Circulating betatrophin correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulin-resistant individuals. Diabetologia 2014; 57: 1204-8
21. Fu Z, Abou-Samra AB, Zhang R. An explanation for recent discrepancies in levels of human circulating betatrophin. Diabetologia 2014; 57: 2232-4