Short-term HIIT and Fatmax training increase aerobic and metabolic fitness in men with class II and III obesity

Obesity

Volumn 23, Issue 10, 2015, Pages 1987-1994

  Lanzi, Stefano ^a,b   Codecasa, Franco ^c   Cornacchia, Mauro ^c   Maestrini, Sabrina ^c   Capodaglio, Paolo ^c   Brunani, Amelia ^c   Fanari, Paolo ^c   Salvadori, Alberto ^c   Malatesta, Davide ^a,b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c ISTITUTO AUXOLOGICO ITALIANO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCOSE; GLYCEROL; INSULIN; LACTIC ACID; BIOLOGICAL MARKER;

ADULT; AEROBIC FITNESS; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DISEASE SEVERITY; EXERCISE; FATTY ACID BLOOD LEVEL; FITNESS; GAS EXCHANGE; GLUCOSE BLOOD LEVEL; GLYCEROL BLOOD LEVEL; HIGH INTENSITY INTERVAL TRAINING; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LACTATE BLOOD LEVEL; MALE; MAXIMAL FAT OXIDATION TRAINING; METABOLIC FITNESS; OBESITY; OXIDATION KINETICS; TRAINING; WHOLE BODY FAT OXIDATION KINETIC; BLOOD; CLINICAL TRIAL; LIPID METABOLISM; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PHYSIOLOGY;

ADULT; BIOMARKERS; EXERCISE; FATTY ACIDS, NONESTERIFIED; HUMANS; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MIDDLE AGED; OBESITY; OXIDATION-REDUCTION; OXYGEN CONSUMPTION;

EID: 84942825643     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.21206     Document Type: Article

References (40)

1. Houmard JA, Pories WJ, Dohm GL., Severe obesity: evidence for a deranged metabolic program in skeletal muscle? Exerc Sport Sci Rev 2012; 40: 204-210.
2. Dumortier M, Brandou F, Perez-Martin A, Fedou C, Mercier J, Brun JF., Low intensity endurance exercise targeted for lipid oxidation improves body composition and insulin sensitivity in patients with the metabolic syndrome. Diabetes Metab 2003; 29: 509-518.
3. Bordenave S, Metz L, Flavier S, et al., Training-induced improvement in lipid oxidation in type 2 diabetes mellitus is related to alterations in muscle mitochondrial activity. Effect of endurance training in type 2 diabetes. Diabetes Metab 2008; 34: 162-168.
4. Venables MC, Jeukendrup AE., Endurance training and obesity: effect on substrate metabolism and insulin sensitivity. Med Sci Sports Exerc 2008; 40: 495-502.
5. Gibala MJ, Little JP, Macdonald MJ, Hawley JA., Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol 2012; 590: 1077-1084.
6. Gillen JB, Gibala MJ., Is high-intensity interval training a time-efficient exercise strategy to improve health and fitness? Appl Physiol Nutr Metab 2014; 39: 409-412.
7. Weston KS, Wisloff U, Coombes JS., High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. Br J Sports Med 2014; 48: 1227-1234.
8. Whyte LJ, Gill JM, Cathcart AJ., Effect of 2 weeks of sprint interval training on health-related outcomes in sedentary overweight/obese men. Metabolism 2010; 59: 1421-1428.
9. Trilk JL, Singhal A, Bigelman KA, Cureton KJ., Effect of sprint interval training on circulatory function during exercise in sedentary, overweight/obese women. Eur J Appl Physiol 2011; 111: 1591-1597.
10. Gibala MJ, Little JP., Just HIT it! A time-efficient exercise strategy to improve muscle insulin sensitivity. J Physiol 2010; 588: 3341-3342.
11. Skleryk JR, Karagounis LG, Hawley JA, Sharman MJ, Laursen PB, Watson G., Two weeks of reduced-volume sprint interval or traditional exercise training does not improve metabolic functioning in sedentary obese men. Diabetes Obes Metab 2013; 15: 1146-1153.
12. Hood MS, Little JP, Tarnopolsky MA, Myslik F, Gibala MJ., Low-volume interval training improves muscle oxidative capacity in sedentary adults. Med Sci Sports Exerc 2011; 43: 1849-1856.
13. Astorino TA, Schubert MM, Palumbo E, et al., Magnitude and time course of changes in maximal oxygen uptake in response to distinct regimens of chronic interval training in sedentary women. Eur J Appl Physiol 2013; 113: 2361-2369.
14. Zouhal H, Jacob C, Delamarche P, Gratas-Delamarche A., Catecholamines and the effects of exercise, training and gender. Sports Med 2008; 38: 401-423.
15. Trapp EG, Chisholm DJ, Boutcher SH., Metabolic response of trained and untrained women during high-intensity intermittent cycle exercise. Am J Physiol Regul Integr Comp Physiol 2007; 293: R2370 -R 2375.
16. Boutcher SH., High-intensity intermittent exercise and fat loss. J Obes 2011; 2011: 868305.
17. Baillot A, Audet M, Baillargeon JP, et al., Impact of physical activity and fitness in class II and III obese individuals: a systematic review. Obes Rev 2014; 15: 721-739.
18. Nordby P, Saltin B, Helge JW., Whole-body fat oxidation determined by graded exercise and indirect calorimetry: a role for muscle oxidative capacity? Scand J Med Sci Sports 2006; 16: 209-214.
19. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (Committee Report). Diabetes Care 1998; 21 (Suppl 1): S5-S19.
20. Lanzi S, Codecasa F, Cornacchia M, et al., Fat oxidation, hormonal and plasma metabolite kinetics during a submaximal incremental test in lean and obese adults. PLoS One 2014; 9: e88707.
21. Bordenave S, Flavier S, Fedou C, Brun JF, Mercier J., Exercise calorimetry in sedentary patients: procedures based on short 3 min steps underestimate carbohydrate oxidation and overestimate lipid oxidation. Diabetes Metab 2007; 33: 379-384.
22. Little JP, Gillen JB, Percival ME, et al., Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. J Appl Physiol 2011; 111: 1554-1560.
23. Frayn KN., Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 1983; 55: 628-634.
24. Cheneviere X, Malatesta D, Peters EM, Borrani F., A mathematical model to describe fat oxidation kinetics during graded exercise. Med Sci Sports Exerc 2009; 41: 1615-1625.
25. Levy JC, Matthews DR, Hermans MP., Correct homeostasis model assessment (HOMA) evaluation uses the computer program. Diabetes Care 1998; 21: 2191-2192.
26. Helgerud J, Hoydal K, Wang E, et al., Aerobic high-intensity intervals improve VO2max more than moderate training. Med Sci Sports Exerc 2007; 39: 665-671.
27. Gibala MJ, Little JP, van Essen M, et al., Short-term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance. J Physiol 2006; 575: 901-911.
28. Egan B, Carson BP, Garcia-Roves PM, et al., Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle. J Physiol 2010; 588: 1779-1790.
29. de Glisezinski I, Moro C, Pillard F, et al., Aerobic training improves exercise-induced lipolysis in SCAT and lipid utilization in overweight men. Am J Physiol Endocrinol Metab 2003; 285: E984-E990.
30. Horowitz JF., Regulation of lipid mobilization and oxidation during exercise in obesity. Exerc Sport Sci Rev 2001; 29: 42-46.
31. Brun JF, Malatesta D, Sartorio A., Maximal lipid oxidation during exercise: A target for individualizing endurance training in obesity and diabetes? J Endocrinol Invest 2012; 35: 686-691.
32. Bajaj M, Suraamornkul S, Romanelli A, et al., Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients. Diabetes 2005; 54: 3148-3153.
33. van Aggel-Leijssen DP, Saris WH, Wagenmakers AJ, Senden JM, van Baak MA., Effect of exercise training at different intensities on fat metabolism of obese men. J Appl Physiol 2002; 92: 1300-1309.
34. Moro C, Bajpeyi S, Smith SR., Determinants of intramyocellular triglyceride turnover: implications for insulin sensitivity. Am J Physiol Endocrinol Metab 2008; 294: E203-E213.
35. Schenk S, Harber MP, Shrivastava CR, Burant CF, Horowitz JF., Improved insulin sensitivity after weight loss and exercise training is mediated by a reduction in plasma fatty acid mobilization, not enhanced oxidative capacity. J Physiol 2009; 587: 4949-4961.
36. Villareal DT, Banks MR, Patterson BW, Polonsky KS, Klein S., Weight loss therapy improves pancreatic endocrine function in obese older adults. Obesity (Silver Spring) 2008; 16: 1349-1354.
37. Boyd JC, Simpson CA, Jung ME, Gurd BJ., Reducing the intensity and volume of interval training diminishes cardiovascular adaptation but not mitochondrial biogenesis in overweight/obese men. PLoS One 2013; 8: e68091.
38. Houmard JA, Tanner CJ, Slentz CA, Duscha BD, McCartney JS, Kraus WE., Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol 2004; 96: 101-106.
39. Romijn JA, Coyle EF, Hibbert J, Wolfe RR., Comparison of indirect calorimetry and a new breath 13C/12C ratio method during strenuous exercise. Am J Physiol 1992; 263: E64-E71.
40. Kelley DE, Goodpaster B, Wing RR, Simoneau JA., Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am J Physiol 1999; 277: E1130-E1141.